Logos Global Management LP

In its 13F for Q2 2026 (holdings as of June 30, 2026, filed August 14, 2026), Logos Global Management LP reported 68 stock positions worth $2.3 billion. Its top holding was Erasca (ERAS) at 9.6% of the portfolio, followed by Abivax SA-ADR (ABVX, 5.9%) and Revolution Medicines (RVMD, 5.6%). Compared with Q1 2026, it opened 25 new positions, sold out of 20, added to 18 and reduced 19. The biggest buy was a new position in Biontech SE-ADR (BNTX) and the biggest sale Revolution Medicines (RVMD, shares −65%).

Most Recent 13F
Q2 2026
Location
San Francisco, CA
CIK
0001792126
Portfolio Value
$2.3B (Q2 2026)
SEC Filing
0001172661-26-003529 ↗ filed Aug 14, 2026

Holdings Value

0$500.0M$1.0B$1.5B$2.0B$2.5B Q1 2024: $950.2M Q1 2024 Q2 2024: $867.8M Q2 2024 Q3 2024: $892.7M Q3 2024 Q4 2024: $854.6M Q4 2024 Q1 2025: $562.5M Q1 2025 Q2 2025: $748.6M Q2 2025 Q3 2025: $1.0B Q3 2025 Q4 2025: $1.5B Q4 2025 Q1 2026: $1.9B Q1 2026 Q2 2026: $2.3B $2.3B Q2 2026

Holdings 68 stocks · $2.3B

ERAS Erasca Inc. 9.58% 12,150,000 $222.6M Add +9.0%
ABVX Abivax SA-ADR 5.87% 1,024,000 $136.5M Add +51.7%
RVMD Revolution Medicines Inc. 5.64% 700,000 $131.1M Reduce -65.0%
IDYA Ideaya Biosciences Inc. 4.81% 3,000,000 $111.8M Reduce -13.0%
BNTX Biontech SE-ADR 4.07% 1,015,000 $94.4M New
VERA Vera Therapeutics Inc. 4.06% 2,200,000 $94.4M New
TNGX Tango Therapeutics Inc. 3.84% 2,850,000 $89.1M Reduce -5.0%
PRAX Praxis Precision Medicines I 3.75% 260,000 $87.0M Reduce -8.8%
CLDX Celldex Therapeutics Inc. 3.36% 2,100,000 $78.1M Add +366.7%
DNTH Dianthus Therapeutics Inc. 3.36% 800,000 $78.0M Add +100.0%
CGON CG Oncology Inc. 3.06% 1,000,000 $71.0M Add +73.9%
IRON Disc Medicine Inc. 2.75% 875,000 $64.0M Add +56.3%
MAZE Maze Therapeutics Inc. 2.49% 1,935,000 $57.7M Add +56.7%
DYN Dyne Therapeutics Inc. 2.44% 2,550,000 $56.6M Add +82.1%
MLTX Moonlake Immunotherapeutics 2.24% 2,675,000 $52.1M Add +78.3%
OCUL Ocular Therapeutix Inc. 2.24% 5,300,000 $52.0M Add +37.7%
DSGN Design Therapeutics Inc. 1.87% 3,000,000 $43.4M Add +53.9%
OLMA Olema Pharmaceuticals Inc. 1.73% 3,208,875 $40.1M No change
BLTE Belite Bio Inc. - ADR 1.66% 250,000 $38.5M New
ACHV Achieve Life Sciences Inc. 1.52% 5,425,000 $35.4M New
TRVI Trevi Therapeutics Inc. 1.51% 1,880,000 $35.1M Reduce -21.7%
COGT Cogent Biosciences Inc. 1.50% 900,000 $34.8M New
AVBP Arrivent Biopharma Inc. 1.50% 1,000,000 $34.7M Add +185.7%
CBIO Crescent Biopharma Inc. 1.47% 1,900,000 $34.2M Add +293.8%
CMPS Compass Pathways PLC 1.37% 2,250,000 $31.8M New
MLYS Mineralys Therapeutics Inc. 1.22% 1,050,000 $28.3M New
REPL Replimune Group Inc. 1.19% 2,500,000 $27.7M New
XENE Xenon Pharmaceuticals Inc. 1.17% 450,000 $27.2M No change
GPCR Structure Therapeutics Inc. 1.16% 500,000 $26.8M No change
IMVT Immunovant Inc. 1.10% 665,000 $25.6M Reduce -38.1%
JBIO Jade Biosciences Inc. 1.08% 1,125,000 $25.0M Add +181.3%
ELVN Enliven Therapeutics Inc. 1.02% 465,000 $23.6M Reduce -13.9%
MANE Veradermics Inc. 0.95% 180,000 $22.1M Add +620.0%
AVTX Avalo Therapeutics Inc. 0.91% 1,150,000 $21.3M Add +283.3%
RCUS Arcus Biosciences Inc. 0.86% 650,000 $20.0M Reduce -45.8%
SMMT Summit Therapeutics Inc. 0.85% 1,350,000 $19.7M New
IMCR Immunocore Holdings PLC-ADR 0.82% 600,000 $19.1M Reduce -60.0%
LBRX LB Pharmaceuticals Inc. 0.82% 585,000 $19.0M Reduce -36.1%
NERV Minerva Neurosciences Inc. 0.79% 3,288,777 $18.3M Add +2.3%
FTH Faeth Therapeutics Inc. 0.78% 722,020 $18.1M Add +2306.7%
CRSP Crispr Therapeutics AG 0.70% 300,000 $16.4M New
DBVT DBV Technologies SA-Spon ADR 0.65% 915,000 $15.0M New
PBLS Parabilis Medicines Inc. 0.62% 525,000 $14.4M New
RYTM Rhythm Pharmaceuticals Inc. 0.60% 125,000 $13.9M Reduce -72.2%
VOR Vor Biopharma Inc. 0.52% 650,000 $12.0M Reduce -13.3%
SRRK Scholar Rock Holding Corp. 0.47% 200,000 $11.0M New
IMMX Immix Biopharma Inc. 0.44% 1,000,000 $10.3M Reduce -18.4%
QTTB Q32 Bio Inc. 0.44% 800,000 $10.2M New
ODTX Odyssey Therapeutics Inc. 0.42% 521,736 $9.8M New
ANNX Annexon Inc. 0.37% 1,500,000 $8.6M New
EDIT Editas Medicine Inc. 0.31% 2,222,000 $7.2M New
RLAY Relay Therapeutics Inc. 0.28% 350,000 $6.5M Reduce -53.3%
ACAD Acadia Pharmaceuticals Inc. 0.27% 250,000 $6.3M Reduce -66.7%
AMLX Amylyx Pharmaceuticals Inc. 0.27% 350,000 $6.3M Reduce -50.0%
HELP Cybin Inc. 0.21% 750,000 $5.0M New
OKUR Onkure Therapeutics Inc. Class A 0.19% 963,855 $4.4M New
TENX Tenax Therapeutics Inc. 0.19% 300,000 $4.4M Reduce -52.0%
DFTX Definium Therapeutics Inc. 0.16% 80,000 $3.8M New
UNCY Unicycive Therapeutics Inc. 0.10% 473,563 $2.2M No change
PTN Palatin Technologies Inc. 0.06% 130,000 $1.4M Reduce -7.1%
QURE Uniqure NV 0.06% 30,000 $1.4M New
JATT Jatt II Acquisition Corp. 0.05% 100,000 $1.1M New
RACC Research Alliance Corp. Class A 0.05% 100,000 $1.1M New
ACRS Aclaris Therapeutics Inc. 0.05% 200,000 $1.1M Reduce -60.0%
LGVN Longeveron Inc. 0.04% 1,287,000 $905K New
GUTS Fractyl Health Inc. 0.03% 1,000,000 $794K No change
SEPN Septerna Inc. 0.03% 23,548 $789K No change
AMAN Amanat Acquisition Corp. Class A 0.02% 50,000 $508K New

Portfolio Sells Q1 2026 → Q2 2026

RVMD Revolution Medicines Inc. Reduce -65.0% 5.64% −4.37
CNTA Centessa Pharmaceuticals Ltd. Sold out 0.00% −4.35
TERN Terns Pharmaceuticals Inc. Sold out 0.00% −4.07
CYTK Cytokinetics Inc. Sold out 0.00% −2.97
UTHR United Therapeutics Corp. Sold out 0.00% −2.44
MDGL Madrigal Pharmaceuticals Inc. Sold out 0.00% −2.29
BIIB Biogen Inc. Sold out 0.00% −1.89
TYRA Tyra Biosciences Inc. Sold out 0.00% −1.68
IMCR Immunocore Holdings PLC-ADR Reduce -60.0% 0.82% −1.51
RYTM Rhythm Pharmaceuticals Inc. Reduce -72.2% 0.60% −1.42
IDYA Ideaya Biosciences Inc. Reduce -13.0% 4.81% −1.11
NAMS Newamsterdam Pharma Co. NV Sold out 0.00% −0.99
PRAX Praxis Precision Medicines I Reduce -8.8% 3.75% −0.98
MIRM Mirum Pharmaceuticals Inc. Sold out 0.00% −0.95
PCVX Vaxcyte Inc. Sold out 0.00% −0.90
CMPX Compass Therapeutics Inc. Sold out 0.00% −0.86
JANX Janux Therapeutics Inc. Sold out 0.00% −0.72
ALKS Alkermes PLC Sold out 0.00% −0.64
ORIC Oric Pharmaceuticals Inc. Sold out 0.00% −0.62
ACAD Acadia Pharmaceuticals Inc. Reduce -66.7% 0.27% −0.59
RCUS Arcus Biosciences Inc. Reduce -45.8% 0.86% −0.47
SLNO Soleno Therapeutics Inc. Sold out 0.00% −0.43
LBRX LB Pharmaceuticals Inc. Reduce -36.1% 0.82% −0.34
CRVS Corvus Pharmaceuticals Inc. Sold out 0.00% −0.34
TENX Tenax Therapeutics Inc. Reduce -52.0% 0.19% −0.33
MGTX Meiragtx Holdings PLC Sold out 0.00% −0.31
VSTM Verastem Inc. Sold out 0.00% −0.27
IMVT Immunovant Inc. Reduce -38.1% 1.10% −0.27
AMLX Amylyx Pharmaceuticals Inc. Reduce -50.0% 0.27% −0.23
VOR Vor Biopharma Inc. Reduce -13.3% 0.52% −0.17
IMMX Immix Biopharma Inc. Reduce -18.4% 0.44% −0.13
IBIO Ibio Inc. Sold out 0.00% −0.13
RLAY Relay Therapeutics Inc. Reduce -53.3% 0.28% −0.10
PHVS Pharvaris NV Sold out 0.00% −0.09
ELVN Enliven Therapeutics Inc. Reduce -13.9% 1.02% −0.07
PTN Palatin Technologies Inc. Reduce -7.1% 0.06% −0.07
ACRS Aclaris Therapeutics Inc. Reduce -60.0% 0.05% −0.05
TRVI Trevi Therapeutics Inc. Reduce -21.7% 1.51% +0.04
TNGX Tango Therapeutics Inc. Reduce -5.0% 3.84% +0.60

Portfolio Buys Q1 2026 → Q2 2026

BNTX Biontech SE-ADR New 4.07% +4.07
VERA Vera Therapeutics Inc. New 4.06% +4.06
CLDX Celldex Therapeutics Inc. Add +366.7% 3.36% +2.63
ABVX Abivax SA-ADR Add +51.7% 5.87% +2.00
BLTE Belite Bio Inc. - ADR New 1.66% +1.66
DNTH Dianthus Therapeutics Inc. Add +100.0% 3.36% +1.63
ACHV Achieve Life Sciences Inc. New 1.52% +1.52
COGT Cogent Biosciences Inc. New 1.50% +1.50
CMPS Compass Pathways PLC New 1.37% +1.37
MLYS Mineralys Therapeutics Inc. New 1.22% +1.22
REPL Replimune Group Inc. New 1.19% +1.19
DYN Dyne Therapeutics Inc. Add +82.1% 2.44% +1.13
AVBP Arrivent Biopharma Inc. Add +185.7% 1.50% +1.08
CGON CG Oncology Inc. Add +73.9% 3.06% +1.05
CBIO Crescent Biopharma Inc. Add +293.8% 1.47% +1.02
IRON Disc Medicine Inc. Add +56.3% 2.75% +0.91
MANE Veradermics Inc. Add +620.0% 0.95% +0.87
SMMT Summit Therapeutics Inc. New 0.85% +0.85
MLTX Moonlake Immunotherapeutics Add +78.3% 2.24% +0.80
DSGN Design Therapeutics Inc. Add +53.9% 1.87% +0.80
JBIO Jade Biosciences Inc. Add +181.3% 1.08% +0.79
FTH Faeth Therapeutics Inc. Add +2306.7% 0.78% +0.73
CRSP Crispr Therapeutics AG New 0.70% +0.70
AVTX Avalo Therapeutics Inc. Add +283.3% 0.91% +0.68
DBVT DBV Technologies SA-Spon ADR New 0.65% +0.65
PBLS Parabilis Medicines Inc. New 0.62% +0.62
MAZE Maze Therapeutics Inc. Add +56.7% 2.49% +0.59
OCUL Ocular Therapeutix Inc. Add +37.7% 2.24% +0.56
SRRK Scholar Rock Holding Corp. New 0.47% +0.47
QTTB Q32 Bio Inc. New 0.44% +0.44
ODTX Odyssey Therapeutics Inc. New 0.42% +0.42
ANNX Annexon Inc. New 0.37% +0.37
EDIT Editas Medicine Inc. New 0.31% +0.31
ERAS Erasca Inc. Add +9.0% 9.58% +0.29
HELP Cybin Inc. New 0.21% +0.21
OKUR Onkure Therapeutics Inc. Class A New 0.19% +0.19
DFTX Definium Therapeutics Inc. New 0.16% +0.16
QURE Uniqure NV New 0.06% +0.06
JATT Jatt II Acquisition Corp. New 0.05% +0.05
RACC Research Alliance Corp. Class A New 0.05% +0.05
LGVN Longeveron Inc. New 0.04% +0.04
AMAN Amanat Acquisition Corp. Class A New 0.02% +0.02
NERV Minerva Neurosciences Inc. Add +2.3% 0.79% −0.21

Options Activity Q1 2026 → Q2 2026

TERN Terns Pharmaceuticals Inc. call Sold out 500,000 $26.4Mbefore exit
ELVN Enliven Therapeutics Inc. call Sold out 500,000 $19.6Mbefore exit
AVTX Avalo Therapeutics Inc. call Sold out 1,000,000 $14.9Mbefore exit

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 68$2.3BERAS, ABVX, RVMD, IDYA, BNTX
Q1 2026 63$1.9BRVMD, ERAS, IDYA, PRAX, CNTA
Q4 2025 63$1.5BRVMD, PRAX, IDYA, OLMA, CDTX
Q3 2025 52$1.0BRVMD, IDYA, AKRO, ARVN, OCUL
Q2 2025 44$748.6MIDYA, AKRO, RVMD, JAZZ, IRON
Q1 2025 38$562.5MIDYA, RVMD, AKRO, JANX, NUVL
Q4 2024 46$854.6MIDYA, JANX, RVMD, CYTK, VERA
Q3 2024 53$892.7MIDYA, GPCR, RVMD, IRON, JANX
Q2 2024Amended 50$867.8MIDYA, ARGX, MRUS, RVMD, GPCR
Q1 2024 49$950.2MIDYA, IMCR, IMVT, OCUL, SRPT