Mersana TherapeuticsMRSN

13F holders, Q4 2025 (December 31)
48holders +3
17new positions
15sold out
5famous investors
$28.86avg. 13F price*

At the end of Q4 2025, 48 institutions reported holding Mersana Therapeutics Inc. (MRSN) in their 13F filings, up 3 from Q3 2025. 17 opened new positions and 15 sold out. The largest holders were Nextech Invest Ltd. ($14.0M), Bain Capital Life Sciences Investors, LLC ($10.0M) and Vanguard Group Inc. ($6.1M). 5 famous investors held it, including Mario Gabelli (0.0% of GAMCO Investors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).

Company
Mersana Therapeutics Inc.
CUSIP
59045L205
Latest filing quarter
Q1 2026

History

Number of 13F holders

01020304050 Q2 2025: 2Q2 2025Q3 2025: 45Q3 2025Q4 2025: 48Q4 2025Q1 2026: 1Q1 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions17$13.0M
Exits15$5.8M

All 13F filers, Q3 2025 → Q4 2025: 550,565 shares bought and 1,434,049 shares sold, net −883,484 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 48 holders

Nextech Invest Ltd. 1.35% No change 482,689 $14.0M
Bain Capital Life Sciences Investors, LLC 0.77% No change 346,545 $10.0M
Vanguard Group Inc. 0.00% Reduce -30.5% 210,301 $6.1M
Rock Springs Capital Management LP 0.23% No change 152,586 $4.4M
Alamea Verwaltungs GmbH 2.25% Reduce -94.4% 24,165 $3.3M
Acadian Asset Management LLC 0.01% Reduce -22.1% 110,882 $3.2M
Affinity Asset Advisors, LLC 0.21% New 100,000 $2.9M
BlackRock, Inc. 0.00% Reduce -28.1% 69,210 $2.0M
Bank of America Corp. 0.00% Reduce -1.0% 65,749 $1.9M
Millennium Management 0.00% Reduce -18.8% 63,305 $1.8M
Groupe la Francaise 0.03% New 61,488 $1.8M
Rangeley Capital, LLC 1.44% New 57,098 $1.7M
Gabelli Funds LLC 0.01% New 47,300 $1.4M
Geode Capital Management, LLC 0.00% Add +5.5% 43,920 $1.3M
Credit Industriel Et Commercial 0.27% New 41,392 $1.2M
AQR Capital Management 0.00% Reduce -20.2% 37,264 $1.1M
Mackenzie Financial Corp. 0.00% Reduce -29.3% 33,834 $967K
Yakira Capital Management, Inc. 0.32% New 32,663 $945K
Citadel Advisors 0.00% New 22,493 $651K
State Street Corp. 0.00% Reduce -34.5% 19,543 $565K
Morgan Stanley 0.00% Reduce -61.7% 18,496 $535K
Deltec Asset Management LLC 0.09% New 18,000 $521K
Knott David M Jr 0.20% New 111,686 $438K
Ieq Capital, LLC 0.00% Reduce -15.0% 12,955 $375K
XTX Topco Ltd 0.01% New 11,948 $346K
Point72 Asset Management 0.00% New 10,364 $300K
GAMCO Investors 0.00% New 10,000 $289K
Northern Trust Corp. 0.00% New 8,586 $248K
OMERS ADMINISTRATION Corp 0.00% New 7,900 $229K
Equitec Proprietary Markets, LLC 0.79% New 5,593 $162K
Cwm, LLC 0.00% Reduce -20.6% 2,286 $66K
BNP Paribas Financial Markets 0.00% Add +105.3% 1,090 $32K
Group One Trading LLC 0.00% Add +11.7% 1,073 $31K
Mint Tower Capital Management B.V. 0.01% New 1,035 $30K
Tower Research Capital LLC (TRC) 0.00% Reduce -75.9% 376 $11K
UBS Group AG 0.00% Reduce -97.4% 221 $6K
Royal Bank of Canada 0.00% Reduce -75.7% 168 $5K
JPMorgan Chase & Co. 0.00% Reduce -98.2% 112 $3K
Osaic Holdings, Inc. 0.00% No change 103 $3K
Lion Point Capital, LP 0.01% Reduce -99.6% 100 $3K
Flagship Harbor Advisors, LLC 0.00% New 76 $2K
SBI Securities Co., Ltd. 0.00% Reduce -1.9% 53 $2K
Wells Fargo & Company 0.00% Reduce -96.8% 40 $1K
Huntington National Bank 0.00% No change 32 $926
SHP Wealth Management 0.00% — 25 $723
FMR LLC 0.00% Reduce -99.8% 8 $231
IFP Advisors, Inc 0.00% Reduce -40.0% 3 $87
Danske Bank A/S 0.00% No change 1 $29

"% of holder's portfolio" is MRSN's weight in each manager's 13F, not the share of Mersana Therapeutics Inc. the manager owns.