Oruka TherapeuticsORKA

13F holders, Q4 2024 (December 31)
66holders +24
26new positions
4sold out
2famous investors
$19.54avg. 13F price*

At the end of Q4 2024, 66 institutions reported holding Oruka Therapeutics Inc. (ORKA) in their 13F filings, up 24 from Q3 2024. 26 opened new positions and 4 sold out. The largest holders were FMR LLC ($106.9M), Fairmount Funds Management LLC ($65.4M) and Venrock Adviser, LLC ($63.7M). 2 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Oruka Therapeutics Inc.
CUSIP
687604108
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300 Q3 2024: 42Q3 2024Q4 2024: 66Q4 2024Q1 2025: 71Q1 2025Q2 2025: 81Q2 2025Q3 2025: 105Q3 2025Q4 2025: 143Q4 2025Q1 2026: 184Q1 2026Q2 2026: 255Q2 2026

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions26$31.7M
Exits4$6.6M

All 13F filers, Q3 2024 → Q4 2024: 8,635,911 shares bought and 2,139,496 shares sold, net +6,496,415 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 66 holders

FMR LLC 0.01% Add +17.7% 5,512,300 $106.9M
Fairmount Funds Management LLC 6.50% Add +5.0% 3,371,922 $65.4M
Venrock Adviser, LLC 4.37% Add +6.5% 3,285,620 $63.7M
RTW Investments, LP 0.57% Add +5.1% 1,945,649 $37.7M
Vanguard Group Inc. 0.00% Add +4161.2% 1,610,651 $31.2M
Commodore Capital LP 2.02% Add +3.6% 1,419,714 $27.5M
Braidwell LP 1.21% Add +122.5% 1,147,676 $27.1M
T. Rowe Price Associates Inc. 0.00% Add +374.5% 1,326,893 $25.7M
Janus Henderson Group PLC 0.01% Add +259.7% 849,410 $16.4M
Perceptive Advisors LLC 0.46% Reduce -31.5% 845,567 $16.4M
Paradigm Biocapital Advisors LP 0.55% Add +13.9% 819,660 $15.9M
BlackRock, Inc. 0.00% Add +3384.2% 751,431 $14.6M
Deep Track Capital, LP 0.55% Reduce -39.3% 750,000 $14.5M
Franklin Resources Inc. 0.00% No change 720,547 $14.0M
Frazier Life Sciences Management, L.P. 0.47% Add +22.2% 583,327 $11.3M
Polar Capital Holdings Plc 0.06% New 550,000 $10.7M
SR One Capital Management, LP 2.03% Add +14.7% 430,330 $8.3M
Redmile Group, LLC 0.56% No change 411,728 $8.0M
Morgan Stanley 0.00% Add +495.9% 405,998 $7.9M
Woodline Partners LP 0.05% Add +0.0% 390,969 $7.6M
Affinity Asset Advisors, LLC 1.22% Add +5.4% 368,698 $7.1M
Point72 Asset Management 0.02% Reduce -25.2% 360,732 $7.0M
Avidity Partners Management LP 0.68% Reduce -55.5% 352,124 $6.8M
Jefferies Financial Group Inc. 0.08% New 350,029 $6.8M
Geode Capital Management, LLC 0.00% Add +2348.6% 342,418 $6.6M
Cable Car Capital, LP 0.49% No change 333,371 $6.5M
Driehaus Capital Management LLC 0.05% No change 308,795 $6.0M
Blackstone Inc. 0.02% New 240,174 $4.7M
Great Point Partners LLC 2.09% Reduce -55.5% 228,803 $4.4M
Qube Research & Technologies Ltd 0.00% Add +267.7% 152,082 $2.9M
Wellington Management Group LLP 0.00% Add +15.8% 95,089 $1.8M
TD Asset Management Inc 0.00% No change 95,076 $1.8M
Barclays PLC 0.00% New 74,583 $1.4M
Adage Capital Partners Gp, L.L.C. 0.00% Reduce -65.4% 69,200 $1.3M
Northern Trust Corp. 0.00% New 64,044 $1.2M
Kennedy Capital Management LLC 0.03% New 60,494 $1.2M
Toronto Dominion Bank 0.00% New 58,332 $1.1M
Manufacturers Life Insurance Company, The 0.00% No change 42,298 $820K
Weiss Asset Management LP 0.02% New 40,000 $776K
683 Capital Management, LLC 0.07% New 33,875 $657K
Millennium Management 0.00% New 30,305 $588K
UBS Group AG 0.00% New 25,162 $488K
State Street Corp. 0.00% New 25,023 $485K
Ensign Peak Advisors, Inc 0.00% No change 25,000 $485K
Allostery Investments LP 0.76% — 20,000 $388K
B Group, Inc. 0.24% — 20,000 $388K
OMERS ADMINISTRATION Corp 0.00% New 19,800 $384K
Jane Street Group, LLC 0.00% New 17,706 $343K
Charles Schwab Investment Management Inc. 0.00% New 15,608 $303K
Squarepoint Ops LLC 0.00% New 12,175 $236K
Citigroup Inc. 0.00% Reduce -70.0% 8,028 $156K
China Universal Asset Management Co., Ltd. 0.01% New 7,421 $144K
AlphaCentric Advisors LLC 0.12% New 6,140 $119K
JPMorgan Chase & Co. 0.00% New 2,800 $54K
Mirae Asset Global Investments Co., Ltd. 0.00% New 1,166 $22K
GF Fund Management Co. LTD. 0.00% — 735 $14K
Tower Research Capital LLC (TRC) 0.00% Reduce -39.5% 584 $11K
BNP Paribas Financial Markets 0.00% New 468 $9K
Bank of America Corp. 0.00% Add +1220.0% 198 $4K
Activest Wealth Management 0.00% No change 166 $3K
Daiwa Securities Group Inc. 0.00% New 116 $2K
Royal Bank of Canada 0.00% New 55 $1K
Group One Trading LLC 0.00% New 23 $446
Parallel Advisors, LLC 0.00% No change 20 $388
National Bank of Canada 0.00% New 8 $155
Aster Capital Management (DIFC) Ltd 0.00% New 5 $97

"% of holder's portfolio" is ORKA's weight in each manager's 13F, not the share of Oruka Therapeutics Inc. the manager owns.