Oruka TherapeuticsORKA
13F holders, Q4 2025 (December 31)143holders +38
39new positions
8sold out
5famous investors
$30.31avg. 13F price*
At the end of Q4 2025, 143 institutions reported holding Oruka Therapeutics Inc. (ORKA) in their 13F filings, up 38 from Q3 2025. 39 opened new positions and 8 sold out. The largest holders were FMR LLC ($220.1M), Venrock Adviser, LLC ($125.7M) and Fairmount Funds Management LLC ($112.3M). 5 famous investors held it, including Andreas Halvorsen (0.2% of Viking Global Investors's portfolio), Steve Cohen (0.0% of Point72 Asset Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Oruka Therapeutics Inc.
- CUSIP
- 687604108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 39 | $104.0M |
| Exits | 8 | $2.4M |
All 13F filers, Q3 2025 → Q4 2025: 8,593,380 shares bought and 3,006,122 shares sold, net +5,587,258 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 143 holders
| FMR LLC | 0.01% | Add +0.1% | 7,261,384 | $220.1M |
| Venrock Adviser, LLC | 6.21% | No change | 4,148,428 | $125.7M |
| Fairmount Funds Management LLC | 8.55% | No change | 3,705,262 | $112.3M |
| BlackRock, Inc. | 0.00% | Add +60.5% | 3,539,415 | $107.3M |
| Viking Global Investors | 0.21% | No change | 2,666,690 | $80.8M |
| Vanguard Group Inc. | 0.00% | Add +38.1% | 2,453,530 | $74.4M |
| Deep Track Capital, LP | 1.49% | Reduce -18.6% | 2,161,510 | $65.5M |
| RTW Investments, LP | 0.62% | Add +5.8% | 2,058,148 | $62.4M |
| Commodore Capital LP | 3.54% | No change | 1,753,054 | $53.1M |
| Paradigm Biocapital Advisors LP | 1.39% | New | 1,710,316 | $51.8M |
| Remedium Capital Partners, LLC | 27.64% | — | 1,552,414 | $47.1M |
| Perceptive Advisors LLC | 0.82% | Add +16.4% | 1,476,501 | $44.8M |
| State Street Corp. | 0.00% | Add +112.2% | 1,383,847 | $41.9M |
| Avoro Capital Advisors LLC | 0.40% | No change | 1,333,340 | $40.4M |
| Blackstone Inc. | 0.15% | Add +37.0% | 1,165,408 | $35.3M |
| Polar Capital Holdings Plc | 0.14% | Reduce -5.2% | 978,288 | $29.7M |
| Geode Capital Management, LLC | 0.00% | Add +36.6% | 942,507 | $28.6M |
| Franklin Resources Inc. | 0.01% | Reduce -11.9% | 938,421 | $28.4M |
| Affinity Asset Advisors, LLC | 1.80% | Reduce -16.4% | 802,342 | $24.3M |
| Mercer Global Advisors Inc. | 0.03% | Reduce -12.6% | 745,277 | $22.6M |
| Citadel Advisors | 0.02% | Add +129.1% | 726,118 | $22.0M |
| Avidity Partners Management LP | 5.77% | No change | 660,424 | $20.0M |
| T. Rowe Price Associates Inc. | 0.00% | Add +3.6% | 649,346 | $19.7M |
| Point72 Asset Management | 0.03% | Reduce -42.1% | 600,000 | $18.2M |
| Woodline Partners LP | 0.07% | Add +0.0% | 574,553 | $17.4M |
| Cormorant Asset Management, LP | 0.92% | No change | 533,340 | $16.2M |
| Synergy Asset Management, LLC | 1.45% | New | 458,946 | $13.9M |
| SR One Capital Management, LP | 1.85% | No change | 430,330 | $13.0M |
| Candriam S.C.A. | 0.06% | Add +9.1% | 400,509 | $12.1M |
| Cable Car Capital, LP | 0.78% | Reduce -20.0% | 400,000 | $12.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +33.4% | 329,496 | $10.0M |
| Northern Trust Corp. | 0.00% | Add +27.9% | 280,904 | $8.5M |
| UBS Group AG | 0.00% | Add +213.1% | 271,013 | $8.2M |
| Soleus Capital Management, L.P. | 0.24% | New | 190,000 | $5.8M |
| Great Point Partners LLC | 1.80% | No change | 183,330 | $5.6M |
| Barclays PLC | 0.00% | Add +81.8% | 173,329 | $5.3M |
| Invesco Ltd. | 0.00% | Add +777.1% | 143,121 | $4.3M |
| Bank of America Corp. | 0.00% | Add +76.3% | 139,272 | $4.2M |
| Longaeva Partners L.P. | 0.47% | New | 128,110 | $3.9M |
| Moody Aldrich Partners LLC | 0.72% | New | 126,812 | $3.8M |
| Morgan Stanley | 0.00% | Reduce -9.4% | 122,198 | $3.7M |
| Deutsche Bank AG | 0.00% | Add +439.5% | 119,329 | $3.6M |
| Kalehua Capital Management LLC | 3.55% | — | 118,524 | $3.6M |
| Sio Capital Management, LLC | 0.59% | New | 118,126 | $3.6M |
| Bank of New York Mellon Corp | 0.00% | Add +61.6% | 114,173 | $3.5M |
| Alyeska Investment Group, L.P. | 0.01% | New | 100,000 | $3.0M |
| Goldman Sachs Group Inc. | 0.00% | Add +370.3% | 92,995 | $2.8M |
| Nuveen, LLC | 0.00% | Add +144.5% | 86,347 | $2.6M |
| Braidwell LP | 0.10% | Reduce -93.9% | 84,795 | $2.6M |
| Wellington Management Group LLP | 0.00% | Reduce -7.0% | 84,716 | $2.6M |
| Secure Asset Management, LLC | 0.39% | New | 81,664 | $2.5M |
| TD Asset Management Inc | 0.00% | Add +74.2% | 79,896 | $2.4M |
| D. E. Shaw & Co. | 0.00% | Reduce -19.9% | 76,415 | $2.3M |
| Aberdeen Group plc | 0.00% | No change | 75,680 | $2.3M |
| B Group, Inc. | 1.68% | No change | 75,000 | $2.3M |
| Palo Alto Investors LP | 0.25% | No change | 59,985 | $1.8M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +18.2% | 61,358 | $1.8M |
| Millennium Management | 0.00% | New | 58,723 | $1.8M |
| American Century Companies Inc. | 0.00% | Add +67.3% | 57,080 | $1.7M |
| Kennedy Capital Management LLC | 0.03% | Add +0.9% | 48,686 | $1.5M |
| Wells Fargo & Company | 0.00% | Add +107.4% | 43,261 | $1.3M |
| Swiss National Bank | 0.00% | New | 43,000 | $1.3M |
| Voya Investment Management LLC | 0.00% | New | 42,503 | $1.3M |
| Rhumbline Advisers | 0.00% | Add +35.3% | 41,017 | $1.2M |
| Alps Advisors Inc. | 0.01% | New | 39,751 | $1.2M |
| Rafferty Asset Management, LLC | 0.00% | Add +201.0% | 38,485 | $1.2M |
| Alliancebernstein L.P. | 0.00% | New | 37,800 | $1.1M |
| Verition Fund Management LLC | 0.01% | New | 35,710 | $1.1M |
| Financial Enhancement Group LLC | 0.14% | Reduce -4.7% | 31,293 | $1.1M |
| Two Sigma Investments, LP | 0.00% | No change | 28,566 | $866K |
| Schroder Investment Management Group | 0.00% | No change | 29,184 | $850K |
| Squarepoint Ops LLC | 0.00% | New | 27,671 | $839K |
| Voleon Capital Management LP | 0.02% | New | 23,548 | $714K |
| State of Wisconsin Investment Board | 0.00% | New | 22,968 | $696K |
| California State Teachers Retirement System | 0.00% | Add +1175.5% | 21,658 | $656K |
| MetLife Investment Management, LLC | 0.00% | Add +29.4% | 21,362 | $647K |
| ADAR1 Capital Management, LLC | 0.05% | No change | 20,840 | $632K |
| JPMorgan Chase & Co. | 0.00% | Add +41.0% | 20,417 | $619K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +53.3% | 20,152 | $608K |
| Hudson Bay Capital Management LP | 0.00% | New | 20,000 | $606K |
| Glenmede Trust Co. NA | 0.00% | — | 19,485 | $591K |
| Legal & General Group Plc | 0.00% | Add +656.7% | 18,744 | $568K |
| Brookwood Investment Group LLC | 0.06% | New | 16,569 | $502K |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 0.01% | No change | 15,406 | $467K |
| Envestnet Asset Management Inc. | 0.00% | New | 15,247 | $462K |
| AlphaQuest LLC | 0.03% | Add +38.5% | 14,901 | $452K |
| Intech Investment Management LLC | 0.00% | Add +18.4% | 14,813 | $449K |
| Profund Advisors LLC | 0.01% | New | 14,623 | $443K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | New | 14,244 | $432K |
| Resolute Capital Asset Partners LLC | 0.18% | Reduce -83.3% | 12,500 | $379K |
| Janus Henderson Group PLC | 0.00% | New | 12,100 | $367K |
| AlphaCentric Advisors LLC | 0.33% | — | 10,880 | $330K |
| Altfest L J & Co. Inc. | 0.04% | Reduce -18.4% | 10,857 | $329K |
| Allianz Asset Management GmbH | 0.00% | New | 10,300 | $312K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +38.7% | 10,207 | $309K |
| Citigroup Inc. | 0.00% | Add +191.6% | 9,828 | $298K |
| Sei Investments Co. | 0.00% | New | 9,676 | $293K |
| Brevan Howard Capital Management LP | 0.01% | New | 9,416 | $285K |
| ProShare Advisors LLC | 0.00% | New | 9,189 | $279K |
| Virtus Investment Advisers, LLC | 0.07% | New | 8,814 | $267K |
"% of holder's portfolio" is ORKA's weight in each manager's 13F, not the share of Oruka Therapeutics Inc. the manager owns.