Prothena Corp.PRTA
13F holders, Q1 2025 (March 31)161holders −9
15new positions
25sold out
4famous investors
$12.37avg. 13F price*
At the end of Q1 2025, 161 institutions reported holding Prothena Corp. PLC (PRTA) in their 13F filings, down 9 from Q4 2024. 15 opened new positions and 25 sold out. The largest holders were EcoR1 Capital, LLC ($143.4M), FMR LLC ($98.3M) and Wellington Management Group LLP ($64.3M). 4 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Prothena Corp. PLC
- CUSIP
- G72800108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 15 | $5.8M |
| Exits | 25 | $6.0M |
All 13F filers, Q4 2024 → Q1 2025: 1,270,477 shares bought and 2,476,065 shares sold, net −1,205,588 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 161 holders
| EcoR1 Capital, LLC | 8.53% | No change | 11,584,280 | $143.4M |
| FMR LLC | 0.01% | Reduce -1.6% | 7,941,402 | $98.3M |
| Wellington Management Group LLP | 0.01% | Add +1.3% | 5,199,528 | $64.3M |
| BlackRock, Inc. | 0.00% | Reduce -1.9% | 4,042,301 | $50.0M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -6.2% | 3,455,856 | $42.8M |
| Armistice Capital, LLC | 0.73% | Reduce -1.8% | 2,196,000 | $27.2M |
| Palo Alto Investors LP | 3.91% | Reduce -4.5% | 1,659,734 | $20.5M |
| State Street Corp. | 0.00% | Reduce -18.3% | 1,521,364 | $18.8M |
| Siren, L.L.C. | 0.90% | Add +16.7% | 1,283,555 | $15.9M |
| Vanguard Group Inc. | 0.00% | Reduce -9.6% | 1,269,271 | $15.7M |
| Geode Capital Management, LLC | 0.00% | Add +5.2% | 1,014,792 | $12.6M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -0.2% | 863,148 | $10.7M |
| Morgan Stanley | 0.00% | Add +0.1% | 719,988 | $8.9M |
| Boxer Capital Management, LLC | 2.57% | No change | 690,000 | $8.5M |
| Finepoint Capital LP | 1.34% | Reduce -2.6% | 640,071 | $7.9M |
| Federated Hermes, Inc. | 0.01% | Reduce -26.8% | 546,255 | $6.8M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -8.3% | 510,462 | $6.3M |
| Rock Springs Capital Management LP | 0.35% | Reduce -23.6% | 492,601 | $6.1M |
| Prosight Management, LP | 1.66% | Reduce -2.4% | 408,122 | $5.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +0.0% | 381,652 | $4.7M |
| Northern Trust Corp. | 0.00% | Reduce -7.6% | 373,703 | $4.6M |
| JPMorgan Chase & Co. | 0.00% | Reduce -4.0% | 371,965 | $4.6M |
| Mariner, LLC | 0.01% | Add +3.1% | 354,650 | $4.4M |
| Birchview Capital, LP | 3.58% | Add +9.3% | 332,974 | $4.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -2.3% | 319,607 | $4.0M |
| Nordea Investment Management AB | 0.00% | New | 307,987 | $3.7M |
| UBS Group AG | 0.00% | Reduce -34.1% | 244,479 | $3.0M |
| Renaissance Technologies | 0.00% | Add +18.8% | 239,900 | $3.0M |
| DCF Advisers, LLC | 1.30% | Add +88.4% | 195,000 | $2.4M |
| PDT Partners, LLC | 0.13% | Add +18.2% | 150,316 | $1.9M |
| Nuveen, LLC | 0.00% | — | 149,961 | $1.9M |
| Bank of New York Mellon Corp | 0.00% | Reduce -2.8% | 146,009 | $1.8M |
| Jane Street Group, LLC | 0.00% | Add +138.9% | 132,640 | $1.6M |
| Bank of America Corp. | 0.00% | Add +10.9% | 131,986 | $1.6M |
| Pinnacle Associates Ltd. | 0.02% | Reduce -2.7% | 100,259 | $1.2M |
| Deutsche Bank AG | 0.00% | Reduce -0.2% | 95,810 | $1.2M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | Reduce -0.4% | 91,482 | $1.1M |
| Citadel Advisors | 0.00% | Add +115.3% | 89,399 | $1.1M |
| Duncan Williams Asset Management, LLC | 0.39% | Add +27.7% | 88,339 | $1.1M |
| Barclays PLC | 0.00% | Reduce -20.8% | 83,381 | $1.0M |
| Hennion & Walsh Asset Management, Inc. | 0.04% | Add +48.5% | 77,637 | $961K |
| Susquehanna International Group, LLP | 0.00% | Add +205.7% | 77,243 | $956K |
| Susquehanna Fundamental Investments, LLC | 0.02% | Reduce -7.3% | 74,772 | $925K |
| SG Americas Securities, LLC | 0.00% | Add +92.9% | 72,559 | $898K |
| Swiss National Bank | 0.00% | No change | 68,700 | $850K |
| Rhumbline Advisers | 0.00% | Reduce -1.5% | 66,079 | $818K |
| Citigroup Inc. | 0.00% | Reduce -3.8% | 65,826 | $815K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -7.1% | 65,231 | $807K |
| TD Asset Management Inc | 0.00% | Reduce -3.1% | 62,694 | $776K |
| Norges Bank | 0.00% | No change | 57,454 | $711K |
| Millennium Management | 0.00% | Reduce -57.4% | 52,467 | $649K |
| Alliancebernstein L.P. | 0.00% | No change | 46,753 | $579K |
| Wells Fargo & Company | 0.00% | Reduce -13.1% | 45,889 | $568K |
| Rafferty Asset Management, LLC | 0.00% | Reduce -43.4% | 43,978 | $544K |
| Massachusetts Financial Services Co. | 0.00% | Reduce -2.2% | 43,816 | $542K |
| Legal & General Group Plc | 0.00% | Reduce -0.1% | 41,354 | $512K |
| ExodusPoint Capital Management, LP | 0.01% | New | 41,272 | $511K |
| Thrivent Financial for Lutherans | 0.00% | No change | 38,626 | $478K |
| Alps Advisors Inc. | 0.00% | Reduce -12.8% | 37,956 | $470K |
| Invesco Ltd. | 0.00% | Reduce -12.2% | 37,638 | $466K |
| American Century Companies Inc. | 0.00% | Add +14.6% | 34,836 | $431K |
| Intech Investment Management LLC | 0.00% | Add +49.1% | 33,375 | $413K |
| California State Teachers Retirement System | 0.00% | No change | 33,243 | $411K |
| Focused Wealth Management, Inc | 0.05% | No change | 32,129 | $398K |
| RBF Capital, LLC | 0.02% | No change | 29,200 | $361K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +0.2% | 27,334 | $340K |
| MetLife Investment Management, LLC | 0.00% | Reduce -1.8% | 25,402 | $314K |
| Edgewood Management LLC | 0.00% | No change | 24,060 | $298K |
| Ensign Peak Advisors, Inc | 0.00% | No change | 21,643 | $268K |
| Purkiss Capital Advisors LLC | 0.20% | Add +101.6% | 21,629 | $268K |
| Dark Forest Capital Management LP | 0.01% | New | 21,059 | $261K |
| Handelsbanken Fonder AB | 0.00% | No change | 20,900 | $259K |
| Corebridge Financial, Inc. | 0.00% | Reduce -1.5% | 20,831 | $258K |
| Franklin Resources Inc. | 0.00% | Add +0.3% | 19,747 | $244K |
| Foundation Wealth Management, LLC | 0.19% | No change | 19,471 | $241K |
| Janus Henderson Group PLC | 0.00% | No change | 18,047 | $237K |
| Jacobs Levy Equity Management, Inc. | 0.00% | New | 18,553 | $230K |
| D. E. Shaw & Co. | 0.00% | New | 17,803 | $220K |
| Man Group plc | 0.00% | Reduce -78.0% | 17,000 | $210K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +0.1% | 16,040 | $198K |
| Two Sigma Investments, LP | 0.00% | Reduce -58.2% | 16,033 | $198K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 15,386 | $190K |
| Shelton Capital Management | 0.00% | New | 15,233 | $189K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 14,000 | $180K |
| New York State Common Retirement Fund | 0.00% | No change | 14,279 | $177K |
| HRT Financial LP | 0.00% | New | 14,036 | $173K |
| Commonwealth Equity Services, LLC | 0.00% | New | 13,320 | $165K |
| Cresset Asset Management, LLC | 0.00% | Reduce -32.5% | 13,125 | $162K |
| HSBC Holdings PLC | 0.00% | Reduce -45.9% | 13,088 | $160K |
| Cary Street Partners Financial LLC | 0.00% | No change | 12,500 | $155K |
| Raymond James Financial Inc. | 0.00% | Reduce -4.8% | 12,487 | $155K |
| Virtus Investment Advisers, LLC | 0.04% | New | 11,891 | $147K |
| Voya Investment Management LLC | 0.00% | Reduce -8.9% | 11,684 | $145K |
| ProShare Advisors LLC | 0.00% | Reduce -19.9% | 11,632 | $144K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -5.4% | 10,797 | $134K |
| Creative Planning | 0.00% | Reduce -33.4% | 10,690 | $132K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | New | 10,164 | $126K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 10,113 | $125K |
| BNP Paribas Financial Markets | 0.00% | Reduce -90.2% | 9,577 | $119K |
| Chicago Partners Investment Group LLC | 0.00% | Add +29.6% | 14,512 | $106K |
| KLP Kapitalforvaltning As | 0.00% | Reduce -48.1% | 6,700 | $83K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 6,552 | $81K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 4,368 | $54K |
| Royal Bank of Canada | 0.00% | Reduce -37.5% | 4,318 | $53K |
| HighMark Wealth Management LLC | 0.01% | Reduce -81.9% | 2,018 | $25K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.5% | 1,801 | $24K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -88.7% | 1,894 | $23K |
| Amundi | 0.00% | Add +3.1% | 2,014 | $23K |
| Brooklyn Investment Group | 0.00% | Add +989.4% | 1,754 | $22K |
| Amalgamated Bank | 0.00% | No change | 1,440 | $18K |
| GF Fund Management Co. LTD. | 0.00% | Add +21.9% | 1,377 | $17K |
| Nisa Investment Advisors, LLC | 0.00% | Add +26.2% | 1,237 | $15K |
| Russell Investments Group, Ltd. | 0.00% | Add +35.5% | 1,194 | $15K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -1.0% | 962 | $12K |
| Farther Finance Advisors, LLC | 0.00% | Add +173.9% | 967 | $11K |
| Lindbrook Capital, LLC | 0.00% | Add +29.1% | 874 | $11K |
| Blue Trust, Inc. | 0.00% | No change | 711 | $9K |
| Cwm, LLC | 0.00% | Reduce -46.6% | 635 | $8K |
| HM Payson & Co. | 0.00% | Reduce -25.0% | 600 | $7K |
| Versant Capital Management, Inc | 0.00% | Reduce -15.6% | 531 | $7K |
| US Bancorp \de | 0.00% | Reduce -40.5% | 512 | $6K |
| PNC Financial Services Group, Inc. | 0.00% | Add +17.3% | 488 | $6K |
| GAMMA Investing LLC | 0.00% | Add +281.9% | 485 | $6K |
| Signaturefd, LLC | 0.00% | Add +2.3% | 360 | $4K |
| Sterling Capital Management LLC | 0.00% | Reduce -44.3% | 331 | $4K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +192.3% | 304 | $4K |
| Aster Capital Management (DIFC) Ltd | 0.00% | Reduce -21.2% | 227 | $4K |
| SVB Wealth LLC | 0.00% | New | 274 | $3K |
| Manchester Capital Management LLC | 0.00% | No change | 250 | $3K |
| Caitong International Asset Management Co., Ltd | 0.00% | Add +107.0% | 238 | $3K |
| Spire Wealth Management | 0.00% | New | 200 | $2K |
| Evelyn Partners Investment Management LLP | 0.00% | No change | 199 | $2K |
| Asset Dedication, LLC | 0.00% | No change | 184 | $2K |
| Daiwa Securities Group Inc. | 0.00% | No change | 195 | $2K |
| Osaic Holdings, Inc. | 0.00% | Reduce -37.8% | 161 | $2K |
| North Capital, Inc. | 0.00% | — | 159 | $2K |
| Sittner & Nelson, LLC | 0.00% | No change | 155 | $2K |
| IFP Advisors, Inc | 0.00% | No change | 132 | $2K |
| Albion Financial Group | 0.00% | No change | 125 | $2K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Add +460.0% | 112 | $1K |
| Gould Capital, LLC | 0.00% | No change | 100 | $1K |
| Harbor Investment Advisory, LLC | 0.00% | No change | 100 | $1K |
| CVA Family Office, LLC | 0.00% | No change | 72 | $891 |
| Parallel Advisors, LLC | 0.00% | No change | 70 | $866 |
| Truvestments Capital LLC | 0.00% | No change | 68 | $842 |
| Coldstream Capital Management Inc. | 0.00% | New | 51 | $632 |
| Rothschild Investment LLC | 0.00% | Add +28.6% | 45 | $557 |
| Larson Financial Group LLC | 0.00% | Add +35.5% | 42 | $520 |
| CIBC Private Wealth Group LLC | 0.00% | No change | 49 | $514 |
| Allworth Financial LP | 0.00% | Add +123.8% | 47 | $454 |
| Parkside Financial Bank & Trust | 0.00% | New | 30 | $372 |
| CoreCap Advisors, LLC | 0.00% | No change | 23 | $285 |
| Key Financial Inc | 0.00% | No change | 12 | $148 |
| Lowe Wealth Advisors, LLC | 0.00% | No change | 10 | $124 |
| Smartleaf Asset Management LLC | 0.00% | New | 9 | $118 |
| Clearstead Advisors, LLC | 0.00% | No change | 4 | $50 |
| Harbour Investments, Inc. | 0.00% | Add +200.0% | 3 | $37 |
| Valley Wealth Managers, Inc. | 0.00% | No change | 3 | $37 |
| Whittier Trust Co. of Nevada Inc. | 0.00% | No change | 3 | $37 |
| CBIZ Investment Advisory Services, LLC | 0.00% | No change | 2 | $25 |
| Covestor Ltd | 0.00% | No change | 4 | $0 |
"% of holder's portfolio" is PRTA's weight in each manager's 13F, not the share of Prothena Corp. PLC the manager owns.