Boxer Capital Management, LLC

In its 13F for Q2 2026 (holdings as of June 30, 2026, filed August 14, 2026), Boxer Capital Management, LLC reported 62 stock positions worth $1.3 billion. Its top holding was Tango Therapeutics (TNGX) at 25.6% of the portfolio, followed by Revolution Medicines (RVMD, 7.1%) and Abivax SA-ADR (ABVX, 6.1%). Compared with Q1 2026, it opened 12 new positions, sold out of 3, added to 17 and reduced 1. The biggest buy was Uniqure (QURE, shares +127%) and the biggest sale an exit from Terns Pharmaceuticals (TERN).

Most Recent 13F
Q2 2026
Location
San Diego, CA
CIK
0002018299
Portfolio Value
$1.3B (Q2 2026)
SEC Filing
0001213900-26-090024 ↗ filed Aug 14, 2026

Holdings Value

0$500.0M$1.0B$1.5B Q4 2024: $1.2B Q4 2024 Q1 2025: $332.4M Q1 2025 Q2 2025: $198.6M Q2 2025 Q3 2025: $313.7M Q3 2025 Q4 2025: $456.8M Q4 2025 Q1 2026: $761.7M Q1 2026 Q2 2026: $1.3B $1.3B Q2 2026

Holdings 62 stocks · $1.3B
TNGX Tango Therapeutics Inc. 25.61% 10,876,219 $340.0M No change
RVMD Revolution Medicines Inc. 7.05% 500,000 $93.6M No change
ABVX Abivax SA-ADR 6.07% 605,000 $80.6M Add +202.5%
QURE Uniqure NV 5.21% 1,503,300 $69.2M Add +127.1%
KOD Kodiak Sciences Inc. 4.34% 1,477,600 $57.6M Add +8.6%
KYMR Kymera Therapeutics Inc. 3.71% 429,100 $49.2M Add +30.4%
DFTX Definium Therapeutics Inc. 3.54% 998,500 $47.0M Add +66.8%
REPL Replimune Group Inc. 3.32% 3,983,000 $44.1M Add +239.0%
CELC Celcuity Inc. 3.28% 416,530 $43.6M Add +85.1%
QTTB Q32 Bio Inc. 3.02% 3,149,310 $40.1M New
CAPR Capricor Therapeutics Inc. 2.53% 1,395,156 $33.6M Add +136.5%
PGEN Precigen Inc. 2.21% 5,150,000 $29.4M Add +47.1%
CORT Corcept Therapeutics Inc. 2.20% 335,500 $29.2M Add +34.2%
SRZN Surrozen Inc. 2.03% 1,105,683 $27.0M Add +44.3%
PTGX Protagonist Therapeutics Inc. 1.57% 170,000 $20.8M No change
VIR Vir Biotechnology Inc. 1.43% 1,866,000 $19.0M No change
PCVX Vaxcyte Inc. 1.42% 325,000 $18.9M No change
URGN Urogen Pharma Ltd. 1.39% 500,000 $18.4M No change
CRVS Corvus Pharmaceuticals Inc. 1.24% 1,100,000 $16.4M No change
PTCT PTC Therapeutics Inc. 1.23% 200,000 $16.3M No change
PRAX Praxis Precision Medicines I 1.17% 46,457 $15.6M No change
AMLX Amylyx Pharmaceuticals Inc. 1.08% 800,000 $14.4M No change
OCUL Ocular Therapeutix Inc. 0.96% 1,300,000 $12.8M Add +271.4%
IRD Opus Genetics Inc. 0.87% 2,815,000 $11.6M Add +25.1%
PALI Palisade Bio Inc. 0.76% 4,799,875 $10.0M No change
APGE Apogee Therapeutics Inc. 0.70% 70,000 $9.3M No change
SYRE Spyre Therapeutics Inc. 0.67% 100,000 $8.9M New
COGT Cogent Biosciences Inc. 0.66% 225,000 $8.7M No change
CYTK Cytokinetics Inc. 0.64% 100,000 $8.5M No change
RLAY Relay Therapeutics Inc. 0.63% 450,000 $8.4M New
CBIO Crescent Biopharma Inc. 0.61% 453,686 $8.2M No change
CTNM Contineum Therapeutics Inc. Class A 0.61% 494,000 $8.1M No change
KZIA Kazia Therapeutics-Spon ADR 0.59% 560,000 $7.9M New
STTK Shattuck Labs Inc. 0.52% 1,000,000 $6.9M New
AVTX Avalo Therapeutics Inc. 0.52% 375,000 $6.9M Add +25.0%
FBRX Forte Biosciences Inc. 0.44% 274,500 $5.8M New
RLMD Relmada Therapeutics Inc. 0.44% 842,106 $5.8M No change
MLTX Moonlake Immunotherapeutics 0.40% 275,000 $5.4M No change
ZURA Zura Bio Ltd. 0.40% 900,000 $5.3M No change
HELP Cybin Inc. 0.39% 790,000 $5.2M Add +23.4%
ODTX Odyssey Therapeutics Inc. 0.39% 275,000 $5.1M New
IMTX Immatics NV 0.36% 475,000 $4.8M New
FTH Faeth Therapeutics Inc. 0.34% 180,505 $4.5M New
GPCR Structure Therapeutics Inc. 0.30% 75,000 $4.0M No change
ORIC Oric Pharmaceuticals Inc. 0.29% 350,000 $3.8M Add +98.3%
ANTX AN2 Therapeutics Inc. 0.27% 749,035 $3.6M No change
NMRA Neumora Therapeutics Inc. 0.26% 2,000,000 $3.4M New
INO Inovio Pharmaceuticals Inc. 0.24% 2,844,994 $3.1M Add +20.0%
ALLO Allogene Therapeutics Inc. 0.23% 1,500,000 $3.1M Reduce -45.0%
SLDB Solid Biosciences Inc. 0.23% 300,000 $3.0M No change
KPTI Karyopharm Therapeutics Inc. 0.22% 302,536 $3.0M No change
CLNN Clene Inc. 0.22% 477,515 $2.9M No change
SRPT Sarepta Therapeutics Inc. 0.20% 150,000 $2.7M No change
MPLT Maplight Therapeutics Inc. 0.20% 75,000 $2.7M New
NRIX Nurix Therapeutics Inc. 0.18% 100,000 $2.4M No change
LBRX LB Pharmaceuticals Inc. 0.17% 70,000 $2.3M No change
EDSA Edesa Biotech Inc. 0.13% 205,000 $1.7M New
IVVD Invivyd Inc. 0.10% 1,500,000 $1.3M No change
UPB Upstream Bio Inc. 0.08% 150,000 $1.0M No change
MIST Milestone Pharmaceuticals Inc. 0.07% 666,666 $893K No change
PEPG Pepgen Inc. 0.04% 272,892 $491K No change
RGNX Regenxbio Inc. 0.01% 15,000 $180K No change
Other holdings (1): bonds, preferreds, convertibles and warrants · $1K (not counted above)
SecurityClassShares / PrincipalValueChange
SRZNW Surrozen Inc.-CW25 *W EXP 08/01/203 66,666$1KNo change

Total filed on the 13F, all lines: $1.3B.

Portfolio Sells Q1 2026 → Q2 2026
TERN Terns Pharmaceuticals Inc. Sold out 0.00% −2.60
SLNO Soleno Therapeutics Inc. Sold out 0.00% −0.88
ALLO Allogene Therapeutics Inc. Reduce -45.0% 0.23% −0.64
KALV Kalvista Pharmaceuticals Inc. Sold out 0.00% −0.05

Portfolio Buys Q1 2026 → Q2 2026
QURE Uniqure NV Add +127.1% 5.21% +3.79
ABVX Abivax SA-ADR Add +202.5% 6.07% +3.15
QTTB Q32 Bio Inc. New 3.02% +3.02
REPL Replimune Group Inc. Add +239.0% 3.32% +2.14
DFTX Definium Therapeutics Inc. Add +66.8% 3.54% +2.05
CORT Corcept Therapeutics Inc. Add +34.2% 2.20% +0.87
SYRE Spyre Therapeutics Inc. New 0.67% +0.67
RLAY Relay Therapeutics Inc. New 0.63% +0.63
KZIA Kazia Therapeutics-Spon ADR New 0.59% +0.59
OCUL Ocular Therapeutix Inc. Add +271.4% 0.96% +0.57
STTK Shattuck Labs Inc. New 0.52% +0.52
FBRX Forte Biosciences Inc. New 0.44% +0.44
PGEN Precigen Inc. Add +47.1% 2.21% +0.43
ODTX Odyssey Therapeutics Inc. New 0.39% +0.39
IMTX Immatics NV New 0.36% +0.36
FTH Faeth Therapeutics Inc. New 0.34% +0.34
NMRA Neumora Therapeutics Inc. New 0.26% +0.26
MPLT Maplight Therapeutics Inc. New 0.20% +0.20
CAPR Capricor Therapeutics Inc. Add +136.5% 2.53% +0.18
EDSA Edesa Biotech Inc. New 0.13% +0.13
KYMR Kymera Therapeutics Inc. Add +30.4% 3.71% +0.11
ORIC Oric Pharmaceuticals Inc. Add +98.3% 0.29% −0.01
HELP Cybin Inc. Add +23.4% 0.39% −0.01
AVTX Avalo Therapeutics Inc. Add +25.0% 0.52% −0.07
CELC Celcuity Inc. Add +85.1% 3.28% −0.09
INO Inovio Pharmaceuticals Inc. Add +20.0% 0.24% −0.31
IRD Opus Genetics Inc. Add +25.1% 0.87% −0.47
SRZN Surrozen Inc. Add +44.3% 2.03% −0.90
KOD Kodiak Sciences Inc. Add +8.6% 4.34% −2.48

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 62$1.3BTNGX, RVMD, ABVX, QURE, KOD
Q1 2026 53$761.7MTNGX, KOD, RVMD, KYMR, CELC
Q4 2025 43$456.8MTNGX, RVMD, KOD, KYMR, CELC
Q3 2025Amended 32$313.7MTNGX, QURE, RVMD, KYMR, KOD
Q2 2025Amended 18$198.6MTNGX, RVMD, REPL, MRUS, KYMR
Q1 2025Amended 26$332.4MRVMD, NUVL, MRUS, RNAM, ANAB
Q4 2024 58$1.2BRVMD, SWTX, NUVL, MRUS, RNAM