Sage TherapeuticsSAGE
13F holders, Q2 2025 (June 30)192holders −6
37new positions
42sold out
6famous investors
$9.12avg. 13F price*
At the end of Q2 2025, 192 institutions reported holding Sage Therapeutics Inc. (SAGE) in their 13F filings, down 6 from Q1 2025. 37 opened new positions and 42 sold out. The largest holders were Madison Avenue Partners, LP ($55.4M), BlackRock, Inc. ($41.5M) and Vanguard Group Inc. ($29.8M). 6 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Sage Therapeutics Inc.
- CUSIP
- 78667J108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 37 | $70.8M |
| Exits | 42 | $67.2M |
All 13F filers, Q1 2025 → Q2 2025: 15,561,404 shares bought and 18,447,452 shares sold, net −2,886,048 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 192 holders
| Madison Avenue Partners, LP | 3.70% | Add +35.7% | 6,077,065 | $55.4M |
| BlackRock, Inc. | 0.00% | Reduce -2.5% | 4,545,458 | $41.5M |
| Vanguard Group Inc. | 0.00% | Reduce -35.7% | 3,265,802 | $29.8M |
| Hudson Bay Capital Management LP | 0.13% | Add +236.8% | 1,952,245 | $17.8M |
| D. E. Shaw & Co. | 0.02% | Reduce -8.2% | 1,917,284 | $17.5M |
| Balyasny Asset Management L.P. | 0.03% | Add +1234.9% | 1,518,170 | $13.8M |
| Geode Capital Management, LLC | 0.00% | Add +4.1% | 1,356,577 | $12.4M |
| Alpine Associates Management Inc. | 0.62% | New | 1,273,348 | $11.6M |
| State Street Corp. | 0.00% | Reduce -1.9% | 1,166,002 | $10.6M |
| 683 Capital Management, LLC | 1.13% | Add +15.0% | 1,150,000 | $10.5M |
| Marshall Wace, LLP | 0.01% | Reduce -34.9% | 1,147,571 | $10.5M |
| Renaissance Technologies | 0.01% | Add +44.6% | 1,113,400 | $10.2M |
| Toronto Dominion Bank | 0.02% | New | 1,082,120 | $9.9M |
| Qube Research & Technologies Ltd | 0.01% | New | 1,082,003 | $9.9M |
| Millennium Management | 0.01% | Add +223.9% | 1,002,709 | $9.1M |
| Harvest Management LLC | 3.94% | Add +22.4% | 889,200 | $8.1M |
| Dimensional Fund Advisors LP | 0.00% | Add +81.5% | 874,166 | $8.0M |
| AQR Capital Management | 0.01% | Reduce -24.9% | 861,366 | $7.9M |
| Rangeley Capital, LLC | 8.66% | Add +89.8% | 730,000 | $6.7M |
| ADAR1 Capital Management, LLC | 1.08% | Reduce -2.8% | 721,599 | $6.6M |
| Newtyn Management, LLC | 0.97% | New | 700,000 | $6.4M |
| Boussard & Gavaudan Investment Management LLP | 1.47% | Reduce -6.2% | 614,939 | $5.6M |
| Jacobs Levy Equity Management, Inc. | 0.02% | Reduce -17.6% | 581,753 | $5.3M |
| Nuveen, LLC | 0.00% | Reduce -7.2% | 555,036 | $5.1M |
| Morgan Stanley | 0.00% | Reduce -62.2% | 529,376 | $4.8M |
| Goldman Sachs Group Inc. | 0.00% | Add +18.5% | 519,107 | $4.7M |
| Northern Trust Corp. | 0.00% | Reduce -1.2% | 462,585 | $4.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +2.7% | 458,248 | $4.2M |
| Glazer Capital, LLC | 0.17% | New | 441,108 | $4.0M |
| OMERS ADMINISTRATION Corp | 0.03% | New | 424,300 | $3.9M |
| AQR Arbitrage LLC | 0.14% | New | 409,055 | $3.7M |
| Monaco Asset Management SAM | 1.27% | Reduce -17.0% | 366,619 | $3.3M |
| HRT Financial LP | 0.01% | Add +120.0% | 330,661 | $3.0M |
| Eisler Capital Management Ltd. | 0.10% | Add +94.2% | 330,150 | $3.0M |
| Y-Intercept (Hong Kong) Ltd | 0.07% | New | 303,888 | $2.8M |
| BCK Capital Management LP | 2.35% | New | 297,040 | $2.7M |
| Jump Financial, LLC | 0.03% | Add +53.4% | 289,341 | $2.6M |
| Two Sigma Investments, LP | 0.00% | Reduce -25.2% | 268,007 | $2.4M |
| Federated Hermes, Inc. | 0.00% | Reduce -79.3% | 246,804 | $2.3M |
| GABELLI & Co INVESTMENT ADVISERS, INC. | 0.32% | New | 224,450 | $2.0M |
| Trexquant Investment LP | 0.02% | Reduce -64.8% | 223,121 | $2.0M |
| Deutsche Bank AG | 0.00% | Reduce -3.6% | 215,905 | $2.0M |
| Gabelli Funds LLC | 0.01% | New | 200,777 | $1.8M |
| Invesco Ltd. | 0.00% | Add +23.3% | 200,332 | $1.8M |
| Two Sigma Advisers, LP | 0.00% | Reduce -38.8% | 198,799 | $1.8M |
| Susquehanna Fundamental Investments, LLC | 0.05% | Reduce -7.2% | 196,284 | $1.8M |
| Cubist Systematic Strategies, LLC | 0.02% | New | 192,258 | $1.8M |
| Verition Fund Management LLC | 0.01% | Add +7.2% | 184,445 | $1.7M |
| Bank of New York Mellon Corp | 0.00% | Add +6.0% | 183,012 | $1.7M |
| Yakira Capital Management, Inc. | 0.62% | New | 182,634 | $1.7M |
| Jane Street Group, LLC | 0.00% | Reduce -7.0% | 179,619 | $1.6M |
| Citadel Advisors | 0.00% | Reduce -83.0% | 178,337 | $1.6M |
| Ameriprise Financial Inc. | 0.00% | Add +158.7% | 169,860 | $1.5M |
| Slotnik Capital, LLC | 0.61% | New | 166,592 | $1.5M |
| Pinnacle Associates Ltd. | 0.02% | Reduce -28.6% | 156,004 | $1.4M |
| Graham Capital Management, L.P. | 0.04% | Add +67.0% | 154,051 | $1.4M |
| Bank of America Corp. | 0.00% | Reduce -28.5% | 145,799 | $1.3M |
| Franklin Resources Inc. | 0.00% | New | 144,917 | $1.3M |
| American Century Companies Inc. | 0.00% | Add +17.2% | 141,828 | $1.3M |
| Ieq Capital, LLC | 0.01% | Reduce -14.5% | 140,831 | $1.3M |
| Susquehanna International Group, LLP | 0.00% | Reduce -30.2% | 139,666 | $1.3M |
| JPMorgan Chase & Co. | 0.00% | Add +402.7% | 132,912 | $1.2M |
| Bardin Hill Management Partners LP | 0.70% | New | 121,519 | $1.1M |
| Tudor Investment Corporation | 0.01% | Reduce -24.2% | 108,377 | $988K |
| Barclays PLC | 0.00% | Add +67.2% | 99,618 | $909K |
| Bridgeway Capital Management, LLC | 0.02% | New | 95,000 | $866K |
| Rhumbline Advisers | 0.00% | Add +8.9% | 91,864 | $838K |
| UBS Group AG | 0.00% | Add +17.2% | 88,333 | $806K |
| AdvisorShares Investments LLC | 0.14% | No change | 83,642 | $763K |
| TIG Advisors, LLC | 0.04% | Reduce -97.0% | 83,200 | $759K |
| Nomura Holdings Inc. | 0.01% | Add +164.0% | 80,000 | $730K |
| Equitec Proprietary Markets, LLC | 2.36% | New | 63,900 | $583K |
| Headlands Technologies LLC | 0.07% | Add +1245.1% | 62,400 | $569K |
| Martingale Asset Management L P | 0.01% | Reduce -14.9% | 62,343 | $569K |
| STRS Ohio | 0.00% | No change | 62,200 | $567K |
| Schonfeld Strategic Advisors LLC | 0.00% | Add +50.0% | 60,000 | $547K |
| Alliancebernstein L.P. | 0.00% | No change | 59,900 | $546K |
| Virtu Financial LLC | 0.03% | New | 56,515 | $515K |
| Cerity Partners LLC | 0.00% | Add +6.5% | 53,300 | $486K |
| Group One Trading LLC | 0.01% | Reduce -12.4% | 50,286 | $459K |
| Skandinaviska Enskilda Banken AB (publ) | 0.00% | New | 50,000 | $456K |
| Public Employees Retirement System of Ohio | 0.00% | Add +100.1% | 49,788 | $454K |
| Citigroup Inc. | 0.00% | Add +9.8% | 47,849 | $436K |
| Cwm, LLC | 0.00% | Reduce -23.2% | 47,174 | $430K |
| ProShare Advisors LLC | 0.00% | Add +221.9% | 46,994 | $429K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.07% | Add +94.1% | 44,310 | $404K |
| T. Rowe Price Associates Inc. | 0.00% | Add +11.7% | 43,762 | $400K |
| Inspire Investing, LLC | 0.04% | Reduce -0.6% | 42,947 | $392K |
| Farallon Capital Management, L.L.C. | 0.00% | No change | 42,800 | $390K |
| Walleye Trading LLC | 0.01% | New | 42,376 | $386K |
| Polymer Capital Management (US) LLC | 0.06% | New | 42,157 | $384K |
| PDT Partners, LLC | 0.02% | Reduce -64.2% | 41,693 | $380K |
| Gsa Capital Partners LLP | 0.03% | Reduce -38.5% | 41,682 | $380K |
| Covestor Ltd | 0.21% | Add +99.6% | 39,473 | $360K |
| Wells Fargo & Company | 0.00% | Add +8.8% | 37,033 | $338K |
| Walleye Capital LLC | 0.00% | Add +195.4% | 35,290 | $322K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Reduce -22.0% | 34,046 | $313K |
| Mariner, LLC | 0.00% | Add +70.7% | 34,150 | $311K |
| MetLife Investment Management, LLC | 0.00% | Add +10.1% | 34,106 | $311K |
| Cannon Global Investment Management, LLC | 0.81% | New | 32,500 | $296K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -4.3% | 31,380 | $286K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -43.8% | 29,307 | $267K |
| Erste Asset Management GmbH | 0.00% | No change | 28,500 | $261K |
| Intech Investment Management LLC | 0.00% | Reduce -5.4% | 27,541 | $251K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | No change | 27,432 | $250K |
| ExodusPoint Capital Management, LP | 0.00% | Reduce -67.1% | 26,125 | $238K |
| Fiduciary Trust Co | 0.00% | No change | 25,999 | $237K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | New | 25,600 | $233K |
| Creative Planning | 0.00% | Reduce -47.9% | 25,143 | $229K |
| Quinn Opportunity Partners LLC | 0.02% | New | 24,888 | $227K |
| Values First Advisors, Inc. | 0.11% | Add +1.9% | 22,296 | $203K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 22,220 | $203K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +0.6% | 20,880 | $190K |
| Axq Capital, LP | 0.06% | New | 20,152 | $184K |
| Squarepoint Ops LLC | 0.00% | New | 19,389 | $177K |
| Wolverine Trading, LLC | 0.00% | Add +58.1% | 18,390 | $168K |
| AlphaQuest LLC | 0.02% | Add +321.8% | 17,003 | $155K |
| Pallas Capital Advisors LLC | 0.01% | Reduce -23.0% | 16,095 | $147K |
| Bank of Montreal | 0.00% | Reduce -4.3% | 15,467 | $141K |
| Voya Investment Management LLC | 0.00% | Reduce -68.6% | 15,328 | $140K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 15,164 | $138K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +30.8% | 13,963 | $127K |
| US Bancorp \de | 0.00% | Add +287.1% | 13,717 | $125K |
| Lazard Asset Management LLC | 0.00% | New | 13,232 | $120K |
| XTX Topco Ltd | 0.00% | Reduce -68.9% | 13,078 | $119K |
| Stifel Financial Corp. | 0.00% | Reduce -2.2% | 12,955 | $118K |
| Merit Financial Group, LLC | 0.00% | Add +17.4% | 12,876 | $117K |
| China Universal Asset Management Co., Ltd. | 0.01% | Add +2.0% | 12,577 | $115K |
| Prelude Capital Management, LLC | 0.01% | Reduce -20.4% | 12,229 | $112K |
| Quantinno Capital Management LP | 0.00% | New | 12,052 | $110K |
| New York State Common Retirement Fund | 0.00% | No change | 12,046 | $110K |
| Two Sigma Securities, LLC | 0.01% | New | 11,714 | $107K |
| GTS Securities LLC | 0.00% | Add +7.9% | 10,921 | $100K |
| Engineers Gate Manager LP | 0.00% | Reduce -74.4% | 10,868 | $99K |
| Clarius Group, LLC | 0.01% | No change | 10,000 | $91K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 8,938 | $82K |
| PenderFund Capital Management Ltd. | 0.04% | New | 8,300 | $76K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +43.8% | 7,185 | $66K |
| BNP Paribas Financial Markets | 0.00% | Reduce -91.6% | 6,061 | $55K |
| Essential Partners LLC | 0.02% | — | 5,924 | $54K |
| Royal Bank of Canada | 0.00% | Add +55.9% | 5,879 | $53K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 5,253 | $48K |
| Legal & General Group Plc | 0.00% | Reduce -46.9% | 5,175 | $47K |
| Osaic Holdings, Inc. | 0.00% | Add +0.4% | 4,183 | $38K |
| FMR LLC | 0.00% | Reduce -50.0% | 4,133 | $38K |
| California State Teachers Retirement System | 0.00% | No change | 4,034 | $37K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +101.9% | 2,782 | $25K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +17.6% | 2,419 | $22K |
| Clearstead Advisors, LLC | 0.00% | New | 1,924 | $18K |
| Caitong International Asset Management Co., Ltd | 0.01% | Add +397.1% | 1,864 | $17K |
| Amalgamated Bank | 0.00% | No change | 1,783 | $16K |
| GF Fund Management Co. LTD. | 0.00% | No change | 1,566 | $14K |
| PNC Financial Services Group, Inc. | 0.00% | Add +187.8% | 1,531 | $14K |
| Sterling Capital Management LLC | 0.00% | Add +55.4% | 1,464 | $13K |
| Parallel Advisors, LLC | 0.00% | No change | 1,384 | $13K |
| True Wealth Design, LLC | 0.00% | Add +52.5% | 1,191 | $11K |
| New England Capital Financial Advisors LLC | 0.00% | No change | 1,153 | $11K |
| Raymond James Financial Inc. | 0.00% | New | 1,054 | $10K |
| Princeton Global Asset Management LLC | 0.00% | No change | 1,000 | $9K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -15.2% | 962 | $9K |
| Brooklyn Investment Group | 0.00% | Add +18.1% | 788 | $7K |
| Tidemark, LLC | 0.00% | No change | 600 | $5K |
| Manchester Capital Management LLC | 0.00% | No change | 550 | $5K |
| Signaturefd, LLC | 0.00% | Reduce -34.7% | 535 | $5K |
| Versant Capital Management, Inc | 0.00% | Reduce -66.0% | 505 | $5K |
| IFP Advisors, Inc | 0.00% | New | 440 | $4K |
| Allworth Financial LP | 0.00% | Add +104.3% | 239 | $2K |
| Daiwa Securities Group Inc. | 0.00% | No change | 239 | $2K |
| Rothschild Investment LLC | 0.00% | Reduce -52.3% | 205 | $2K |
| GAMMA Investing LLC | 0.00% | Reduce -81.5% | 189 | $2K |
| Comerica Bank | 0.00% | No change | 120 | $1K |
| Tsfg, LLC | 0.00% | No change | 75 | $1K |
| Bell Investment Advisors, Inc | 0.00% | No change | 107 | $976 |
| TFC Financial Management, Inc. | 0.00% | No change | 100 | $912 |
| Atlantic Union Bankshares Corp | 0.00% | New | 100 | $912 |
| Fifth Third Bancorp | 0.00% | New | 84 | $766 |
| Parkside Financial Bank & Trust | 0.00% | New | 60 | $547 |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 0.00% | No change | 50 | $456 |
| Truvestments Capital LLC | 0.00% | No change | 39 | $356 |
| FSA Wealth Management LLC | 0.00% | No change | 35 | $319 |
| North Star Investment Management Corp. | 0.00% | No change | 14 | $128 |
| Jones Financial Companies LLLP | 0.00% | No change | 12 | $110 |
| SouthState Bank Corp | 0.00% | No change | 9 | $82 |
| Wolff Wiese Magana LLC | 0.00% | No change | 7 | $64 |
| Raffa Wealth Management, LLC | 0.00% | No change | 6 | $55 |
| ORG Partners LLC | 0.00% | No change | 5 | $45 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -40.0% | 3 | $27 |
| Blue Trust, Inc. | 0.00% | No change | 2 | $18 |
| Huntington National Bank | 0.00% | No change | 1 | $9 |
| First Horizon Advisors, Inc. | 0.00% | No change | 1 | $9 |
| Activest Wealth Management | 0.00% | No change | 1 | $9 |
| Bessemer Group Inc. | 0.00% | No change | 37 | $0 |
"% of holder's portfolio" is SAGE's weight in each manager's 13F, not the share of Sage Therapeutics Inc. the manager owns.