Sera Prognostics Inc. Class ASERA

13F holders, Q4 2025 (December 31)
57holders −5
5new positions
8sold out
3famous investors
$2.95avg. 13F price*

At the end of Q4 2025, 57 institutions reported holding Sera Prognostics Inc. Class A (SERA) in their 13F filings, down 5 from Q3 2025. 5 opened new positions and 8 sold out. The largest holders were Baker Bros. Advisors LP ($16.2M), Whetstone Capital Advisors, LLC ($10.2M) and Aberdeen Group plc ($6.7M). 3 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).

Company
Sera Prognostics Inc. Class A
CUSIP
81749D107
Latest filing quarter
Q2 2026

History

Number of 13F holders

020406080 Q1 2024: 52Q1 2024Q2 2024: 65Q2 2024Q3 2024: 61Q3 2024Q4 2024: 73Q4 2024Q1 2025: 71Q1 2025Q2 2025: 59Q2 2025Q3 2025: 62Q3 2025Q4 2025: 57Q4 2025Q1 2026: 56Q1 2026Q2 2026: 47Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions5$345K
Exits8$1.5M

All 13F filers, Q3 2025 → Q4 2025: 340,083 shares bought and 843,592 shares sold, net −503,509 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 57 holders

Baker Bros. Advisors LP 0.10% No change 5,498,170 $16.2M
Whetstone Capital Advisors, LLC 3.18% Reduce -4.8% 3,459,713 $10.2M
Aberdeen Group plc 0.01% No change 2,279,699 $6.7M
Vivo Capital, LLC 0.31% No change 1,650,440 $4.9M
Vanguard Group Inc. 0.00% Add +1.8% 1,239,449 $3.7M
Citadel Advisors 0.00% Add +8.2% 707,614 $2.1M
Captrust Financial Advisors 0.00% Reduce -10.9% 536,766 $1.6M
Geode Capital Management, LLC 0.00% Add +1.1% 334,639 $987K
AWM Investment Company, Inc. 0.06% No change 207,382 $612K
BlackRock, Inc. 0.00% Add +4.3% 186,751 $551K
State Street Corp. 0.00% No change 124,792 $368K
Millennium Management 0.00% Reduce -11.1% 113,178 $334K
Gsa Capital Partners LLP 0.03% Add +64.5% 107,235 $316K
Corient Private Wealth LP 0.00% No change 100,000 $290K
Northern Trust Corp. 0.00% Add +9.1% 96,535 $285K
Morgan Stanley 0.00% Reduce -3.6% 80,968 $239K
Bank of New York Mellon Corp 0.00% No change 75,267 $222K
Perigon Wealth Management, LLC 0.00% No change 72,685 $214K
Susquehanna International Group, LLP 0.00% Add +219.7% 71,532 $211K
Jane Street Group, LLC 0.00% New 68,826 $203K
Requisite Capital Management, LLC 0.03% No change 55,648 $164K
Twelve Points Wealth Management LLC 0.04% No change 43,388 $160K
Ballentine Partners, LLC 0.00% No change 49,664 $147K
Bridgeway Capital Management, LLC 0.00% No change 45,705 $135K
HighTower Advisors, LLC 0.00% No change 42,234 $125K
Barclays PLC 0.00% Add +267.4% 36,722 $108K
Squarepoint Ops LLC 0.00% Reduce -61.0% 36,322 $107K
Qube Research & Technologies Ltd 0.00% Add +20.3% 28,982 $85K
Goldman Sachs Group Inc. 0.00% Reduce -47.9% 28,599 $84K
Birch Hill Investment Advisors LLC 0.00% No change 27,293 $81K
UBS Group AG 0.00% Add +2.7% 25,195 $74K
Cetera Investment Advisers 0.00% New 25,000 $74K
Dimensional Fund Advisors LP 0.00% Add +2.3% 22,934 $67K
Two Sigma Investments, LP 0.00% Reduce -30.8% 21,964 $65K
Lido Advisors, LLC 0.00% Reduce -25.0% 16,623 $50K
FMR LLC 0.00% No change 14,845 $44K
Wagner Wealth Management, LLC 0.01% Add +2.3% 12,686 $37K
Riverview Capital Advisers, LLC 0.01% Reduce -0.5% 12,669 $37K
Focus Partners Wealth 0.00% No change 12,156 $36K
Charles Schwab Investment Management Inc. 0.00% Reduce -0.1% 12,085 $36K
Point72 Asset Management 0.00% New 11,403 $34K
Abel Hall, LLC 0.01% No change 11,037 $33K
Wealth Enhancement Advisory Services, LLC 0.00% New 10,639 $31K
Deutsche Bank AG 0.00% No change 8,729 $26K
Geneos Wealth Management Inc. 0.00% Add +73.3% 7,800 $23K
Bank of America Corp. 0.00% Reduce -14.2% 4,670 $14K
Cwm, LLC 0.00% Reduce -0.1% 1,006 $3K
Tower Research Capital LLC (TRC) 0.00% New 945 $3K
Optiver Holding B.V. 0.00% No change 412 $1K
Torren Management, LLC 0.00% — 389 $1K
Fortitude Family Office, LLC 0.00% No change 301 $888
BNP Paribas Financial Markets 0.00% No change 236 $696
JPMorgan Chase & Co. 0.00% No change 222 $655
Citigroup Inc. 0.00% Add +3900.0% 200 $590
Nisa Investment Advisors, LLC 0.00% No change 129 $381
SBI Securities Co., Ltd. 0.00% Reduce -12.5% 7 $21
Royal Bank of Canada 0.00% Reduce -98.2% 40 $0

"% of holder's portfolio" is SERA's weight in each manager's 13F, not the share of Sera Prognostics Inc. Class A the manager owns.