SynlogicSYBX

13F holders, Q3 2025 (September 30)
23holders +4
7new positions
3sold out
2famous investors
$1.67avg. 13F price*

At the end of Q3 2025, 23 institutions reported holding Synlogic Inc. (SYBX) in their 13F filings, up 4 from Q2 2025. 7 opened new positions and 3 sold out. The largest holders were Cable Car Capital, LP ($5.5M), NEA Management Company, LLC ($4.9M) and Vanguard Group Inc. ($332K). 2 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Synlogic Inc.
CUSIP
87166L209
Latest filing quarter
Q2 2026

History

Number of 13F holders

0510152025 Q1 2024: 17Q1 2024Q2 2024: 17Q2 2024Q3 2024: 17Q3 2024Q4 2024: 18Q4 2024Q1 2025: 18Q1 2025Q2 2025: 19Q2 2025Q3 2025: 23Q3 2025Q4 2025: 25Q4 2025Q1 2026: 2Q1 2026Q2 2026: 1Q2 2026

Total Exit/New Position Q2 2025 → Q3 2025

InstitutionsTotal Value
New Positions7$100K
Exits3$59K

All 13F filers, Q2 2025 → Q3 2025: 90,266 shares bought and 206,848 shares sold, net −116,582 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 23 holders

Cable Car Capital, LP 4.14% No change 3,312,219 $5.5M
NEA Management Company, LLC 0.27% No change 2,922,772 $4.9M
Vanguard Group Inc. 0.00% Add +7.3% 196,461 $332K
Geode Capital Management, LLC 0.00% Add +2.1% 67,665 $114K
Renaissance Technologies 0.00% Add +65.9% 39,510 $66K
Citadel Advisors 0.00% New 29,011 $49K
Ikarian Capital, LLC 0.01% No change 20,422 $35K
BlackRock, Inc. 0.00% No change 19,757 $33K
Northern Trust Corp. 0.00% New 19,469 $32K
XTX Topco Ltd 0.00% New 11,173 $19K
State Street Corp. 0.00% No change 10,176 $17K
FMR LLC 0.00% Reduce -96.8% 5,323 $9K
Morgan Stanley 0.00% Reduce -2.7% 1,095 $2K
SBI Securities Co., Ltd. 0.00% Reduce -5.5% 103 $172
Bank of America Corp. 0.00% Reduce -7.3% 64 $107
BNP Paribas Financial Markets 0.00% No change 24 $40
Jones Financial Companies LLLP 0.00% New 20 $35
Hilltop National Bank 0.00% No change 20 $33
Wells Fargo & Company 0.00% New 5 $8
JPMorgan Chase & Co. 0.00% No change 1 $2
Barclays PLC 0.00% New 1 $2
Danske Bank A/S 0.00% No change 1 $2
Citigroup Inc. 0.00% New 1 $2

"% of holder's portfolio" is SYBX's weight in each manager's 13F, not the share of Synlogic Inc. the manager owns.