SynlogicSYBX
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 25 institutions reported holding Synlogic Inc. (SYBX) in their 13F filings, up 2 from Q3 2025. 5 opened new positions and 3 sold out. The largest holders were Cable Car Capital, LP ($3.7M), NEA Management Company, LLC ($3.3M) and Vanguard Group Inc. ($225K). 2 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Synlogic Inc.
- CUSIP
- 87166L209
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 5 | $61K |
| Exits | 3 | $45 |
All 13F filers, Q3 2025 → Q4 2025: 225,068 shares bought and 482 shares sold, net +224,586 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 25 holders
| Cable Car Capital, LP | 0.24% | No change | 3,312,219 | $3.7M |
| NEA Management Company, LLC | 0.17% | No change | 2,922,772 | $3.3M |
| Vanguard Group Inc. | 0.00% | Add +2.3% | 201,060 | $225K |
| Citadel Advisors | 0.00% | Add +388.1% | 141,608 | $159K |
| Renaissance Technologies | 0.00% | Add +116.7% | 85,627 | $96K |
| Geode Capital Management, LLC | 0.00% | Add +5.9% | 71,645 | $80K |
| DRW Securities, LLC | 0.00% | New | 24,363 | $27K |
| Ikarian Capital, LLC | 0.00% | Reduce -2.2% | 19,966 | $22K |
| BlackRock, Inc. | 0.00% | No change | 19,757 | $22K |
| Northern Trust Corp. | 0.00% | No change | 19,469 | $22K |
| Jane Street Group, LLC | 0.00% | New | 14,998 | $17K |
| XTX Topco Ltd | 0.00% | Add +28.9% | 14,398 | $16K |
| Susquehanna International Group, LLP | 0.00% | New | 11,623 | $13K |
| State Street Corp. | 0.00% | No change | 10,176 | $11K |
| FMR LLC | 0.00% | No change | 5,323 | $6K |
| UBS Group AG | 0.00% | New | 2,531 | $3K |
| Morgan Stanley | 0.00% | No change | 1,095 | $1K |
| Flagship Harbor Advisors, LLC | 0.00% | New | 1,033 | $1K |
| SBI Securities Co., Ltd. | 0.00% | No change | 103 | $115 |
| Bank of America Corp. | 0.00% | Add +3.1% | 66 | $73 |
| BNP Paribas Financial Markets | 0.00% | No change | 24 | $27 |
| Hilltop National Bank | 0.00% | No change | 20 | $22 |
| JPMorgan Chase & Co. | 0.00% | No change | 1 | $1 |
| Danske Bank A/S | 0.00% | No change | 1 | $1 |
| Citigroup Inc. | 0.00% | No change | 1 | $1 |
"% of holder's portfolio" is SYBX's weight in each manager's 13F, not the share of Synlogic Inc. the manager owns.