10X Genomics Inc. Class ATXG
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 323 institutions reported holding 10X Genomics Inc. Class A (TXG) in their 13F filings, up 6 from Q3 2025. 53 opened new positions and 57 sold out. The largest holders were Vanguard Group Inc. ($212.3M), ARK Investment Management ($206.6M) and FMR LLC ($194.4M). 8 famous investors held it, including Cathie Wood (1.4% of ARK Investment Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- 10X Genomics Inc. Class A
- CUSIP
- 88025U109
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 53 | $100.0M |
| Exits | 57 | $26.6M |
All 13F filers, Q3 2025 → Q4 2025: 17,445,988 shares bought and 17,149,856 shares sold, net +296,132 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 323 holders
| Vanguard Group Inc. | 0.00% | Reduce -1.9% | 13,017,914 | $212.3M |
| ARK Investment Management | 1.37% | Add +6.6% | 12,667,369 | $206.6M |
| FMR LLC | 0.01% | Add +40.9% | 11,917,482 | $194.4M |
| BlackRock, Inc. | 0.00% | Add +5.9% | 10,014,462 | $163.3M |
| Sumitomo Mitsui Trust Group, Inc. | 0.05% | Add +2.1% | 5,492,189 | $89.6M |
| Amova Asset Management Americas, Inc. | 1.03% | Add +2.0% | 5,486,153 | $89.4M |
| Quantinno Capital Management LP | 0.15% | Add +33.6% | 4,667,203 | $76.1M |
| Morgan Stanley | 0.00% | Add +13.5% | 3,196,893 | $52.1M |
| Goldman Sachs Group Inc. | 0.01% | Add +15.4% | 3,087,267 | $50.4M |
| Geode Capital Management, LLC | 0.00% | Add +2.9% | 2,789,784 | $45.5M |
| Jacobs Levy Equity Management, Inc. | 0.17% | Reduce -10.4% | 2,639,999 | $43.1M |
| AQR Capital Management | 0.02% | Reduce -5.4% | 2,579,051 | $41.9M |
| State Street Corp. | 0.00% | Reduce -0.3% | 2,512,519 | $41.0M |
| Bank of America Corp. | 0.00% | Reduce -46.2% | 1,837,520 | $30.0M |
| Renaissance Technologies | 0.04% | Add +48.4% | 1,550,539 | $25.3M |
| Dimensional Fund Advisors LP | 0.01% | Add +100.9% | 1,517,581 | $24.8M |
| Capital World Investors | 0.00% | No change | 1,452,300 | $23.7M |
| Wellington Management Group LLP | 0.00% | Reduce -66.2% | 1,448,765 | $23.6M |
| Casdin Capital, LLC | 1.42% | New | 1,400,000 | $22.8M |
| T. Rowe Price Investment Management, Inc. | 0.01% | Reduce -4.7% | 1,279,503 | $20.9M |
| Two Sigma Advisers, LP | 0.04% | Add +5.4% | 1,264,900 | $20.6M |
| Millennium Management | 0.01% | Reduce -77.2% | 1,242,366 | $20.3M |
| Voloridge Investment Management, LLC | 0.07% | Reduce -7.0% | 1,228,703 | $20.0M |
| Two Sigma Investments, LP | 0.03% | Add +95.4% | 1,155,691 | $18.8M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -3.4% | 1,106,322 | $18.0M |
| Northern Trust Corp. | 0.00% | Reduce -4.4% | 993,380 | $16.2M |
| JPMorgan Chase & Co. | 0.00% | Reduce -13.5% | 928,426 | $15.1M |
| UBS Group AG | 0.00% | Add +13.4% | 861,000 | $14.0M |
| Freshford Capital Management, LLC | 5.45% | New | 833,302 | $13.6M |
| Ieq Capital, LLC | 0.04% | Reduce -6.8% | 760,096 | $12.4M |
| Trexquant Investment LP | 0.11% | Reduce -27.2% | 752,634 | $12.3M |
| ARCH Venture Management, LLC | 1.85% | New | 737,539 | $12.0M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.03% | Add +123.5% | 709,579 | $11.6M |
| Federated Hermes, Inc. | 0.02% | Reduce -1.0% | 644,908 | $10.5M |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 0.71% | Add +31.9% | 632,079 | $10.3M |
| Clough Capital Partners L P | 0.90% | New | 610,374 | $10.0M |
| Janus Henderson Group PLC | 0.00% | Reduce -41.5% | 545,826 | $8.9M |
| Russell Investments Group, Ltd. | 0.01% | Reduce -5.9% | 533,947 | $8.7M |
| Simplify Asset Management Inc. | 0.13% | New | 485,977 | $7.9M |
| Sands Capital Alternatives, LLC | 1.52% | No change | 481,770 | $7.9M |
| Man Group plc | 0.01% | Reduce -33.9% | 393,064 | $6.4M |
| Algert Global LLC | 0.10% | Reduce -32.1% | 390,280 | $6.4M |
| Ameriprise Financial Inc. | 0.00% | Add +12.0% | 383,169 | $6.2M |
| Bank of New York Mellon Corp | 0.00% | Reduce -7.4% | 350,964 | $5.7M |
| Wells Fargo & Company | 0.00% | Add +42.5% | 344,950 | $5.6M |
| Invesco Ltd. | 0.00% | Add +21.2% | 334,300 | $5.5M |
| Nomura Holdings Inc. | 0.02% | New | 325,783 | $5.3M |
| Bellevue Group AG | 0.10% | Add +2.6% | 322,060 | $5.3M |
| Barclays PLC | 0.00% | Reduce -37.1% | 317,982 | $5.2M |
| Susquehanna Portfolio Strategies, LLC | 0.08% | No change | 298,230 | $4.9M |
| American Century Companies Inc. | 0.00% | Add +14.4% | 271,654 | $4.4M |
| Vestmark Advisory Solutions, Inc. | 0.06% | Reduce -1.4% | 270,668 | $4.4M |
| Franklin Resources Inc. | 0.00% | Reduce -28.5% | 250,016 | $4.1M |
| Principal Financial Group Inc. | 0.00% | Add +53.5% | 249,007 | $4.1M |
| Qube Research & Technologies Ltd | 0.01% | Add +123.0% | 245,636 | $4.0M |
| Nuveen, LLC | 0.00% | Add +3.5% | 236,403 | $3.9M |
| CenterBook Partners LP | 0.18% | New | 230,772 | $3.8M |
| Ossiam | 0.07% | No change | 229,300 | $3.7M |
| Canada Pension Plan Investment Board | 0.00% | Add +18.9% | 229,300 | $3.7M |
| Lazard Asset Management LLC | 0.01% | Add +80.7% | 228,745 | $3.7M |
| Pictet Asset Management Holding SA | 0.00% | Reduce -3.6% | 229,227 | $3.7M |
| Summit Trail Advisors, LLC | 0.06% | Reduce -1.9% | 220,386 | $3.6M |
| Tao Capital Management LP | 2.96% | No change | 210,862 | $3.4M |
| Quantedge Capital Pte Ltd | 1.59% | New | 203,953 | $3.3M |
| Swiss National Bank | 0.00% | Add +4.8% | 203,000 | $3.3M |
| Caprock Group, LLC | 0.07% | Add +59.4% | 190,913 | $3.1M |
| Focus Partners Wealth | 0.00% | Add +334.4% | 189,059 | $3.1M |
| Osaic Holdings, Inc. | 0.00% | Add +16.1% | 183,363 | $3.0M |
| Stifel Financial Corp. | 0.00% | Reduce -5.0% | 182,624 | $3.0M |
| HRT Financial LP | 0.01% | New | 181,152 | $3.0M |
| Bridgewater Associates | 0.01% | New | 177,734 | $2.9M |
| D. E. Shaw & Co. | 0.00% | Add +7.1% | 174,468 | $2.8M |
| Jump Financial, LLC | 0.04% | Add +100.7% | 171,192 | $2.8M |
| Harvard Management Co. Inc. | 0.13% | No change | 170,000 | $2.8M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +14.3% | 169,589 | $2.8M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.00% | New | 169,075 | $2.8M |
| Exome Asset Management LLC | 1.32% | No change | 163,658 | $2.7M |
| Financial Consulate, Inc. | 0.35% | No change | 156,457 | $2.6M |
| Corient Private Wealth LP | 0.00% | Add +129.9% | 149,027 | $2.4M |
| Rhumbline Advisers | 0.00% | Reduce -11.9% | 143,440 | $2.3M |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +17.6% | 118,706 | $2.3M |
| Citigroup Inc. | 0.00% | Reduce -48.0% | 135,955 | $2.2M |
| Citadel Advisors | 0.00% | New | 130,820 | $2.1M |
| Cerity Partners LLC | 0.00% | Reduce -3.1% | 129,251 | $2.1M |
| Public Employees Retirement System of Ohio | 0.01% | Add +7.3% | 127,250 | $2.1M |
| Deerfield Management Company, L.P. | 0.03% | Reduce -51.5% | 126,574 | $2.1M |
| California State Teachers Retirement System | 0.00% | Add +41.6% | 126,293 | $2.1M |
| Alliancebernstein L.P. | 0.00% | No change | 126,200 | $2.1M |
| Cwm, LLC | 0.01% | Reduce -0.7% | 124,970 | $2.0M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +3.4% | 121,427 | $2.0M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -22.6% | 118,371 | $1.9M |
| Royal Bank of Canada | 0.00% | Reduce -92.4% | 108,112 | $1.8M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Add +7.3% | 108,215 | $1.8M |
| Fortis Group Advisors, LLC | 0.28% | Add +311.5% | 82,918 | $1.7M |
| Legal & General Group Plc | 0.00% | Reduce -12.4% | 101,896 | $1.7M |
| Fred Alger Management, LLC | 0.01% | Add +55.5% | 101,683 | $1.7M |
| Deutsche Bank AG | 0.00% | Reduce -38.1% | 101,629 | $1.7M |
| Acadian Asset Management LLC | 0.00% | Add +12.7% | 98,271 | $1.6M |
| Gotham Asset Management | 0.01% | Add +400.3% | 94,717 | $1.5M |
| Engineers Gate Manager LP | 0.02% | Reduce -55.0% | 93,378 | $1.5M |
"% of holder's portfolio" is TXG's weight in each manager's 13F, not the share of 10X Genomics Inc. Class A the manager owns.