Zenas BiopharmaZBIO
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 119 institutions reported holding Zenas Biopharma Inc. (ZBIO) in their 13F filings, up 39 from Q3 2025. 41 opened new positions and 8 sold out. The largest holders were FMR LLC ($279.7M), SR One Capital Management, LP ($182.9M) and Enavate Sciences Gp, LLC ($142.3M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Cliff Asness (0.0% of AQR Capital Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Zenas Biopharma Inc.
- CUSIP
- 98937L105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 41 | $107.9M |
| Exits | 8 | $42.3M |
All 13F filers, Q3 2025 → Q4 2025: 9,619,850 shares bought and 3,213,664 shares sold, net +6,406,186 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 119 holders
| FMR LLC | 0.01% | Add +59.8% | 7,704,255 | $279.7M |
| SR One Capital Management, LP | 25.90% | Add +2.6% | 5,037,854 | $182.9M |
| Enavate Sciences Gp, LLC | 28.08% | Add +4.2% | 3,919,159 | $142.3M |
| NEA Management Company, LLC | 6.52% | Add +28.9% | 3,523,219 | $127.9M |
| Federated Hermes, Inc. | 0.16% | Add +45.9% | 2,715,578 | $98.6M |
| Fairmount Funds Management LLC | 6.11% | Add +16.7% | 2,209,025 | $80.2M |
| NVP Associates, LLC | 26.16% | No change | 1,838,482 | $66.8M |
| BlackRock, Inc. | 0.00% | Add +43.9% | 1,767,518 | $64.2M |
| Vanguard Group Inc. | 0.00% | Add +25.0% | 1,453,065 | $52.8M |
| Novo Holdings A/S | 4.09% | Reduce -27.5% | 1,450,000 | $52.6M |
| Royalty Pharma Sub-Manager, LLC | 26.77% | — | 1,263,150 | $45.9M |
| Polar Capital Holdings Plc | 0.18% | New | 1,057,609 | $38.4M |
| Wellington Management Group LLP | 0.01% | Reduce -0.3% | 855,334 | $31.1M |
| Vivo Capital, LLC | 2.00% | Reduce -27.9% | 853,495 | $31.0M |
| EcoR1 Capital, LLC | 1.31% | New | 789,500 | $28.7M |
| ArrowMark Colorado Holdings LLC | 0.60% | Reduce -8.9% | 751,161 | $27.3M |
| Pivotal bioVenture Partners Investment Advisor LLC | 8.31% | Reduce -24.0% | 591,991 | $21.5M |
| Geode Capital Management, LLC | 0.00% | Add +25.2% | 588,393 | $21.4M |
| Rock Springs Capital Management LP | 0.94% | Reduce -13.5% | 502,077 | $18.2M |
| State Street Corp. | 0.00% | Add +16.1% | 438,294 | $15.9M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -1.4% | 369,248 | $13.4M |
| NEXTBio Capital Management LP | 6.86% | — | 321,983 | $11.7M |
| Point72 Asset Management | 0.02% | New | 368,400 | $9.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +19.5% | 213,193 | $7.7M |
| Balyasny Asset Management L.P. | 0.01% | New | 193,153 | $7.0M |
| Invesco Ltd. | 0.00% | Add +28.9% | 187,968 | $6.8M |
| Skandinaviska Enskilda Banken AB (publ) | 0.02% | New | 163,860 | $5.9M |
| Northern Trust Corp. | 0.00% | Add +16.6% | 155,366 | $5.6M |
| Voloridge Investment Management, LLC | 0.02% | New | 133,439 | $4.8M |
| Goldman Sachs Group Inc. | 0.00% | New | 130,698 | $4.7M |
| Morgan Stanley | 0.00% | Add +44.6% | 128,335 | $4.7M |
| Eversept Partners, LP | 0.25% | Reduce -23.8% | 121,016 | $4.4M |
| Superstring Capital Management LP | 1.62% | Reduce -13.8% | 83,353 | $3.0M |
| AQR Capital Management | 0.00% | Add +218.2% | 78,220 | $2.8M |
| UBS Group AG | 0.00% | Add +95.8% | 69,495 | $2.5M |
| Bank of New York Mellon Corp | 0.00% | Add +24.3% | 51,802 | $1.9M |
| Schroder Investment Management Group | 0.00% | Reduce -55.0% | 50,636 | $1.9M |
| Nuveen, LLC | 0.00% | Add +147.8% | 50,850 | $1.8M |
| Millennium Management | 0.00% | Reduce -31.6% | 49,160 | $1.8M |
| Bank of America Corp. | 0.00% | Add +218.4% | 47,160 | $1.7M |
| Alps Advisors Inc. | 0.01% | Add +119.9% | 44,077 | $1.6M |
| Barclays PLC | 0.00% | Add +50.3% | 34,377 | $1.2M |
| Swiss National Bank | 0.00% | New | 31,600 | $1.1M |
| Citadel Advisors | 0.00% | New | 24,459 | $888K |
| Rhumbline Advisers | 0.00% | Add +3.5% | 21,946 | $797K |
| JPMorgan Chase & Co. | 0.00% | Add +231.8% | 21,726 | $789K |
| Wells Fargo & Company | 0.00% | Add +69.8% | 21,151 | $768K |
| Alliancebernstein L.P. | 0.00% | No change | 18,350 | $666K |
| California State Teachers Retirement System | 0.00% | Add +1271.3% | 15,701 | $570K |
| Squarepoint Ops LLC | 0.00% | New | 15,541 | $564K |
| Two Sigma Investments, LP | 0.00% | Reduce -25.9% | 15,100 | $548K |
| Voya Investment Management LLC | 0.00% | New | 14,725 | $535K |
| Susquehanna International Group, LLP | 0.00% | New | 13,678 | $497K |
| China Universal Asset Management Co., Ltd. | 0.04% | New | 13,314 | $483K |
| Legal & General Group Plc | 0.00% | Add +862.1% | 13,027 | $473K |
| Deutsche Bank AG | 0.00% | Add +4.5% | 12,781 | $464K |
| Creative Planning | 0.00% | Add +3.3% | 12,273 | $446K |
| XTX Topco Ltd | 0.01% | New | 12,183 | $442K |
| Los Angeles Capital Management LLC | 0.00% | New | 14,447 | $432K |
| State of Wisconsin Investment Board | 0.00% | New | 10,221 | $371K |
| Voleon Capital Management LP | 0.01% | New | 10,187 | $370K |
| MetLife Investment Management, LLC | 0.00% | No change | 10,100 | $367K |
| Schonfeld Strategic Advisors LLC | 0.00% | New | 9,127 | $331K |
| Gsa Capital Partners LLP | 0.03% | New | 8,956 | $325K |
| Intech Investment Management LLC | 0.00% | New | 8,863 | $322K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +17.7% | 8,780 | $319K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | New | 8,400 | $305K |
| Janus Henderson Group PLC | 0.00% | New | 7,900 | $287K |
| Mariner, LLC | 0.00% | New | 7,676 | $279K |
| VARCOV Co. | 0.11% | — | 7,335 | $266K |
| BNP Paribas Financial Markets | 0.00% | Add +126.9% | 7,138 | $259K |
| Marshall Wace, LLP | 0.00% | New | 7,100 | $258K |
| Virtus Investment Advisers, LLC | 0.06% | New | 6,554 | $238K |
| Manufacturers Life Insurance Company, The | 0.00% | New | 6,256 | $227K |
| New York State Common Retirement Fund | 0.00% | No change | 6,200 | $225K |
| Brevan Howard Capital Management LP | 0.00% | New | 6,173 | $224K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -0.3% | 5,824 | $211K |
| ProShare Advisors LLC | 0.00% | New | 5,820 | $211K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 4,499 | $163K |
| KLP Kapitalforvaltning As | 0.00% | New | 3,400 | $123K |
| STRS Ohio | 0.00% | No change | 2,800 | $102K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | New | 2,608 | $95K |
| Citigroup Inc. | 0.00% | Add +1150.5% | 2,351 | $85K |
| Cwm, LLC | 0.00% | Add +48.3% | 2,178 | $79K |
| Simplex Trading, LLC | 0.00% | New | 1,974 | $72K |
| Ameritas Investment Partners, Inc. | 0.00% | Reduce -14.9% | 1,368 | $50K |
| Russell Investments Group, Ltd. | 0.00% | No change | 1,345 | $49K |
| Sterling Capital Management LLC | 0.00% | Reduce -3.0% | 1,087 | $39K |
| GF Fund Management Co. LTD. | 0.00% | New | 1,054 | $38K |
| US Bancorp \de | 0.00% | Reduce -7.2% | 884 | $32K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -42.7% | 795 | $29K |
| Amalgamated Bank | 0.00% | Add +13.2% | 593 | $22K |
| Royal Bank of Canada | 0.00% | Reduce -95.4% | 544 | $20K |
| Signaturefd, LLC | 0.00% | Add +17.2% | 389 | $14K |
| GAMMA Investing LLC | 0.00% | Reduce -2.2% | 179 | $6K |
| Daiwa Securities Group Inc. | 0.00% | New | 179 | $6K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 115 | $4K |
| Torren Management, LLC | 0.00% | — | 95 | $3K |
| J.Safra Asset Management Corp | 0.00% | New | 92 | $3K |
| Farther Finance Advisors, LLC | 0.00% | Add +258.3% | 86 | $3K |
"% of holder's portfolio" is ZBIO's weight in each manager's 13F, not the share of Zenas Biopharma Inc. the manager owns.