Novo Holdings A/S

In its 13F for Q2 2026 (holdings as of June 30, 2026, filed August 14, 2026), Novo Holdings A/S reported 25 stock positions worth $1.7 billion. Its top holding was Edgewise Therapeutics (EWTX) at 12.6% of the portfolio, followed by ASML Holding NV-NY Reg SHS (ASML, 11.0%) and Hemab Therapeutics (COAG, 8.9%). Compared with Q1 2026, it opened 6 new positions, sold out of 3, added to 2 and reduced 8. The biggest buy was a new position in Hemab Therapeutics (COAG) and the biggest sale an exit from Apogee Therapeutics (APGE).

Most Recent 13F
Q2 2026
Location
HELLERUP, G7
CIK
0001388325
Portfolio Value
$1.7B (Q2 2026)
SEC Filing
0001388325-26-000042 ↗ filed Aug 14, 2026

Holdings Value

0$500.0M$1.0B$1.5B$2.0B$2.5B Q1 2024: $1.4B Q1 2024 Q2 2024: $1.9B Q2 2024 Q3 2024: $2.0B Q3 2024 Q4 2024: $1.7B Q4 2024 Q1 2025: $1.3B Q1 2025 Q2 2025: $1.4B Q2 2025 Q3 2025: $1.6B Q3 2025 Q4 2025: $1.3B Q4 2025 Q1 2026: $1.2B Q1 2026 Q2 2026: $1.7B $1.7B Q2 2026

Holdings 25 stocks · $1.7B

EWTX Edgewise Therapeutics Inc. 12.62% 5,350,000 $217.4M No change
ASML ASML Holding NV-NY Reg SHS filed as ASML HLDG NV 10.97% 94,946 $188.9M No change
COAG Hemab Therapeutics Holdings 8.92% 4,180,550 $153.6M New
BN Brookfield Corp. 8.68% 3,496,245 $149.5M No change
MPLT Maplight Therapeutics Inc. 7.67% 3,686,622 $132.1M No change
MIRM Mirum Pharmaceuticals Inc. 7.65% 1,125,000 $131.7M Reduce -15.1%
AVLN Avalyn Pharma Inc. 7.42% 3,883,289 $127.8M New
CRM Salesforce Inc. 3.58% 393,187 $61.6M No change
AVBP Arrivent Biopharma Inc. 3.03% 1,500,000 $52.1M Reduce -22.8%
ELVN Enliven Therapeutics Inc. 2.95% 1,000,000 $50.8M Reduce -21.9%
CRNX Crinetics Pharmaceuticals Inc. 2.87% 1,320,000 $49.4M Reduce -14.8%
PHVS Pharvaris NV 2.81% 1,400,000 $48.4M Reduce -20.0%
FND Floor & Decor Holdings Inc. Class A 2.75% 797,000 $47.3M New
PCVX Vaxcyte Inc. 2.70% 800,000 $46.5M Reduce -7.0%
FDMT 4D Molecular Therapeutics Inc. 2.51% 3,249,178 $43.2M Reduce -11.0%
VRDN Viridian Therapeutics Inc. 2.28% 2,135,000 $39.2M Add +6.8%
CLDX Celldex Therapeutics Inc. 2.21% 1,025,000 $38.1M Reduce -14.6%
ALMS Alumis Inc. 1.80% 1,100,000 $31.0M New
XENE Xenon Pharmaceuticals Inc. 1.70% 485,438 $29.3M No change
BABA Alibaba Group Holding-SP ADR 1.43% 257,327 $24.7M No change
DYN Dyne Therapeutics Inc. 1.24% 960,394 $21.3M New
BBOT Bridgebio Oncology Therapeut 1.00% 2,250,000 $17.1M Add +2.9%
INSM Insmed Inc. 0.75% 120,723 $12.9M New
MQ Marqeta Inc. 0.42% 441,558 $7.2M No change
LNZA Lanzatech Global Inc. 0.06% 158,148 $1.1M No change

Portfolio Sells Q1 2026 → Q2 2026

APGE Apogee Therapeutics Inc. Sold out 0.00% −3.07
BMRN Biomarin Pharmaceutical Inc. Sold out 0.00% −3.02
MIRM Mirum Pharmaceuticals Inc. Reduce -15.1% 7.65% −2.27
CRNX Crinetics Pharmaceuticals Inc. Reduce -14.8% 2.87% −1.69
PCVX Vaxcyte Inc. Reduce -7.0% 2.70% −1.35
PHVS Pharvaris NV Reduce -20.0% 2.81% −1.19
ELVN Enliven Therapeutics Inc. Reduce -21.9% 2.95% −1.12
CLDX Celldex Therapeutics Inc. Reduce -14.6% 2.21% −0.87
AVBP Arrivent Biopharma Inc. Reduce -22.8% 3.03% −0.60
VALN Valneva SE - ADR Sold out 0.00% −0.54
FDMT 4D Molecular Therapeutics Inc. Reduce -11.0% 2.51% −0.24

Portfolio Buys Q1 2026 → Q2 2026

COAG Hemab Therapeutics Holdings New 8.92% +8.92
AVLN Avalyn Pharma Inc. New 7.42% +7.42
FND Floor & Decor Holdings Inc. Class A New 2.75% +2.75
ALMS Alumis Inc. New 1.80% +1.80
DYN Dyne Therapeutics Inc. New 1.24% +1.24
INSM Insmed Inc. New 0.75% +0.75
BBOT Bridgebio Oncology Therapeut Add +2.9% 1.00% −0.59
VRDN Viridian Therapeutics Inc. Add +6.8% 2.28% −0.89

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 25$1.7BEWTX, ASML, COAG, BN, MPLT
Q1 2026 22$1.2BEWTX, BN, ASML, MIRM, MPLT
Q4 2025 24$1.3BBN, EWTX, ASML, MIRM, CRM
Q3 2025 27$1.6BVTI, BN, ASML, MIRM, EWTX
Q2 2025 29$1.4BVTI, BN, ASML, CRM, MIRM
Q1 2025 31$1.3BVTI, BN, EWTX, ASML, CRM
Q4 2024 34$1.7BVTI, BN, TEM, EWTX, ASML
Q3 2024 37$2.0BVTI, TEM, BN, EWTX, CORT
Q2 2024Amended 38$1.9BVTI, BN, TEM, ASML, CRM
Q1 2024 35$1.4BASML, BN, CRM, EPC, CORT