AlphaCentric Advisors LLC

In its 13F for Q2 2024 (holdings as of June 30, 2024, filed July 25, 2024), AlphaCentric Advisors LLC reported 217 stock positions worth $135.8 million. Its top holding was United Therapeutics (UTHR) at 3.4% of the portfolio, followed by Biocryst Pharmaceuticals (BCRX, 3.1%) and Rithm Capital (RITM, 3.1%). Compared with Q1 2024, it opened 35 new positions, sold out of 46, added to 55 and reduced 86. The biggest buy was Sarepta Therapeutics (SRPT, shares +2688%) and the biggest sale an exit from Urogen Pharma (URGN).

Most Recent 13F
Q2 2026
Location
SAN JUAN, PR
CIK
0001913464
Portfolio Value
$135.8M (Q2 2024)
SEC Filing
0001162044-24-000737 ↗ filed Jul 25, 2024

Holdings Value

0$50.0M$100.0M$150.0M$200.0M Q1 2024: $165.8M Q1 2024 Q2 2024: $135.8M $135.8M Q2 2024 Q3 2024: $134.5M Q3 2024 Q4 2024: $100.2M Q4 2024 Q4 2025: $100.3M Q4 2025 Q1 2026: $100.1M Q1 2026 Q2 2026: $118.0M Q2 2026

Holdings 217 stocks · $135.8M

UTHR United Therapeutics Corp. 3.40% 14,500 $4.6M Reduce -9.4%
BCRX Biocryst Pharmaceuticals Inc. 3.07% 675,000 $4.2M No change
RITM Rithm Capital Corp. 3.06% 380,966 $4.2M Reduce -9.5%
PFE Pfizer Inc. 2.88% 140,000 $3.9M Reduce -20.0%
HRMY Harmony Biosciences Holdings 2.71% 122,000 $3.7M No change
PCRX Pacira Biosciences Inc. 2.48% 117,500 $3.4M No change
ARGX Argenx SE - ADR 2.30% 7,250 $3.1M Reduce -9.4%
LKFT Lakefront Biotherapeutic-ADR filed as GALAPAGOS NV 1.98% 108,500 $2.7M Add +3.3%
MTG Mgic Investment Corp. 1.82% 114,379 $2.5M No change
EFC Ellington Financial Inc. 1.79% 201,602 $2.4M Reduce -9.0%
MIRM Mirum Pharmaceuticals Inc. 1.61% 64,000 $2.2M Reduce -31.9%
DX Dynex Capital Inc. 1.60% 181,492 $2.2M No change
ONC Beone Medicines Ltd.-ADR filed as BEIGENE LTD 1.58% 15,000 $2.1M Reduce -10.4%
QURE Uniqure NV 1.52% 460,000 $2.1M No change
FOLD Amicus Therapeutics Inc. 1.48% 202,500 $2.0M Add +15.7%
DCGO Docgo Inc. 1.48% 650,000 $2.0M No change
RWT Redwood Trust Inc. 1.38% 288,343 $1.9M No change
MFA Mfa Financial Inc. 1.31% 167,725 $1.8M No change
CLDX Celldex Therapeutics Inc. 1.29% 47,500 $1.8M Add +23.4%
CERE Cerevel Therapeutics Holding 1.28% 42,500 $1.7M No change
CHRS Coherus Oncology Inc. 1.27% 1,000,000 $1.7M No change
ACAD Acadia Pharmaceuticals Inc. 1.20% 100,000 $1.6M Add +122.2%
AVBP Arrivent Biopharma Inc. 1.17% 86,000 $1.6M Add +3.6%
RPRX Royalty Pharma PLC Class A 1.17% 60,000 $1.6M No change
QQQ Invesco QQQ Trust Series 1 1.15% 3,257 $1.6M Add +188.7%
QQQM Invesco Nasdaq 100 ETF 1.15% 7,899 $1.6M Add +188.3%
DVAX Dynavax Technologies Corp. 1.07% 130,000 $1.5M Add +6.1%
MITT TPG Mortgage Investment Trus 1.02% 208,879 $1.4M No change
MDT Medtronic PLC 1.01% 17,500 $1.4M Reduce -14.6%
ITCI Intra-Cellular Therapies Inc. 1.01% 20,000 $1.4M No change
BMRN Biomarin Pharmaceutical Inc. 1.00% 16,500 $1.4M Add +6.5%
GSK GSK PLC-Spon ADR 0.99% 35,000 $1.3M No change
ELS Equity Lifestyle Properties 0.99% 20,611 $1.3M No change
ACT Enact Holdings Inc. 0.96% 42,367 $1.3M No change
EXAS Exact Sciences Corp. 0.93% 30,000 $1.3M Add +3.5%
BCYC Bicycle Therapeutics PLC-ADR 0.89% 60,000 $1.2M No change
AXSM Axsome Therapeutics Inc. 0.89% 15,000 $1.2M Reduce -53.9%
SNPS Synopsys Inc. 0.88% 2,000 $1.2M Reduce -20.0%
SRPT Sarepta Therapeutics Inc. 0.87% 7,500 $1.2M Add +2688.1%
JAZZ Jazz Pharmaceuticals PLC 0.86% 11,000 $1.2M Add +29.4%
ADAM Adamas Trust Inc. 0.86% 200,963 $1.2M No change
TWO HARBORS INV CORP (TWO 6.25 01/15/26) 0.85% 1,205,000 $1.2M Reduce -62.4%
STXS Stereotaxis Inc. 0.80% 600,000 $1.1M No change
GPCR Structure Therapeutics Inc. 0.75% 26,000 $1.0M Reduce -5.5%
AMPH Amphastar Pharmaceuticals Inc. 0.74% 25,000 $1.0M New
KPTI Karyopharm Therapeutics Inc. 0.72% 1,125,000 $976K No change
RWT HOLDINGS INC (RWT 5.75 10/01/25) filed as RWT HLDGS INC 0.72% 1,000,000 $975K No change
TRML Tourmaline Bio Inc. 0.71% 75,000 $965K Add +22.8%
NBIX Neurocrine Biosciences Inc. 0.71% 7,000 $964K No change
IMVT Immunovant Inc. 0.71% 36,500 $964K Reduce -4.0%
PENNYMAC CORP (PMT 5.5 11/01/24) 0.70% 965,000 $957K Reduce -50.9%
ROIV Roivant Sciences Ltd. 0.68% 88,000 $930K Reduce -2.2%
ENOV Enovis Corp. 0.67% 20,000 $904K New
ISRG Intuitive Surgical Inc. 0.66% 2,000 $890K Reduce -33.3%
VKTX Viking Therapeutics Inc. 0.64% 16,500 $875K Reduce -8.3%
PTGX Protagonist Therapeutics Inc. 0.64% 25,000 $866K No change
SNY Sanofi-ADR 0.63% 17,500 $849K Add +16.7%
CATX Perspective Therapeutics Inc. 0.60% 82,000 $818K New
VRNA Verona Pharma Ltd. 0.60% 56,000 $810K No change
AGNC AGNC Investment Corp. 0.59% 84,646 $808K No change
NVDA Nvidia Corp. 0.55% 6,009 $742K Add +783.7%
NARI Inari Medical Inc. 0.53% 15,000 $722K Reduce -76.2%
EMBC Embecta Corp. 0.52% 56,500 $706K Reduce -49.3%
DYN Dyne Therapeutics Inc. 0.52% 20,000 $706K No change
SYM Symbotic Inc. 0.52% 20,000 $703K Reduce -20.0%
VALN Valneva SE - ADR 0.48% 88,252 $649K Add +42.3%
ARAY Accuray Inc. 0.47% 350,000 $637K No change
SGMT Sagimet Biosciences Inc. Class A 0.47% 185,000 $633K No change
RVNC Revance Therapeutics Inc. 0.46% 245,000 $630K No change
ONIT Onity Group Inc. 0.45% 25,567 $613K No change
VYNE THERAPEUTICS INC 0.45% 310,500 $612K Reduce -30.2%
PRCT Procept Biorobotics Corp. 0.45% 10,000 $611K Reduce -60.0%
SOUN Soundhound AI Inc. Class A 0.44% 150,000 $593K Reduce -25.0%
AVAV Aerovironment Inc. 0.42% 3,150 $574K Reduce -60.6%
SHY iShares 1-3 Year Treasury Bo 0.42% 7,016 $573K Add +28.6%
CABA Cabaletta Bio Inc. 0.39% 70,000 $524K Add +7.7%
BBJP JPMorgan Betabuilders Japan 0.36% 8,623 $487K Reduce -1.4%
REDWOOD TRUST INC (RWT 7.75 06/15/27) 0.36% 500,000 $486K No change
EWA iShares MSCI Australia ETF 0.36% 19,853 $485K Reduce -4.1%
IEI iShares 3-7 Year Treasury Bo 0.36% 4,186 $483K Add +29.1%
IWD iShares Russell 1000 Value E 0.35% 2,762 $482K Reduce -68.2%
RPV Invesco S&P 500 Pure Value E 0.35% 5,715 $477K Reduce -68.0%
HIG Hartford Insurance Group Inc. 0.34% 4,653 $468K Add +99.6%
AUPH Aurinia Pharmaceuticals Inc. 0.34% 80,000 $457K No change
COST Costco Wholesale Corp. 0.33% 534 $454K Add +70.6%
RSG Republic Services Inc. 0.31% 2,158 $419K Add +86.2%
NUVB Nuvation Bio Inc. 0.29% 135,000 $394K No change
IEF iShares 7-10 Year Treasury B 0.29% 4,188 $392K Add +30.1%
L Loews Corp. 0.29% 5,226 $391K Add +30.2%
JPM JPMorgan Chase & Co. 0.28% 1,884 $381K Add +94.4%
ACGL Arch Capital Group Ltd. 0.28% 3,710 $374K Add +23.9%
PBP Invesco S&P 500 Buywrite ETF 0.26% 16,023 $355K Reduce -0.6%
CWB SS SPDR BB Conv Sec ETF 0.26% 4,925 $355K Reduce -0.9%
PFF iShares Preferred & Income S 0.26% 11,157 $352K Add +0.7%
EMB iShares JP Morgan Usd Emergi 0.26% 3,973 $352K Reduce -1.6%
BKLN Invesco Senior Loan ETF 0.26% 16,683 $351K Reduce -1.1%
EMHY iShares J.P. Morgan Em High 0.26% 9,446 $350K Reduce -2.3%
VYM Vanguard High DVD Yield ETF 0.26% 2,936 $348K Reduce -4.9%
DWX State Street SPDR S&P Intern 0.25% 9,964 $343K Reduce -3.4%
DAL Delta Air Lines Inc. 0.25% 7,165 $340K Reduce -9.7%

Show all 217 holdings

Portfolio Sells Q1 2024 → Q2 2024

URGN Urogen Pharma Ltd. Sold out 0.00% −1.30
CORT Corcept Therapeutics Inc. Sold out 0.00% −1.29
NARI Inari Medical Inc. Reduce -76.2% 0.53% −1.29
CATX Perspective Therapeutics Inc. Sold out 0.00% −1.26
TWO HARBORS INV CORP (TWO 6.25 01/15/26) Reduce -62.4% 0.85% −0.98
KALV Kalvista Pharmaceuticals Inc. Reduce -98.1% 0.02% −0.91
AXSM Axsome Therapeutics Inc. Reduce -53.9% 0.89% −0.68
RPV Invesco S&P 500 Pure Value E Reduce -68.0% 0.35% −0.60
IWD iShares Russell 1000 Value E Reduce -68.2% 0.35% −0.58
DCPH Deciphera Pharmaceuticals Inc. Sold out 0.00% −0.57
LUNR Intuitive Machines Inc. Sold out 0.00% −0.57
RRX Regal Rexnord Corp. Sold out 0.00% −0.54
ALNT Allient Inc. Sold out 0.00% −0.54
PENNYMAC CORP (PMT 5.5 11/01/24) Reduce -50.9% 0.70% −0.47
GMED Globus Medical Inc. Class A Sold out 0.00% −0.40
VYNE THERAPEUTICS INC Reduce -30.2% 0.45% −0.37
EMBC Embecta Corp. Reduce -49.3% 0.52% −0.37
AVAV Aerovironment Inc. Reduce -60.6% 0.42% −0.32
AGMIT MERGER SUB LLC (MITT 6.75 09/15/24) Sold out 0.00% −0.30
PRCT Procept Biorobotics Corp. Reduce -60.0% 0.45% −0.30
MBB iShares MBS ETF Sold out 0.00% −0.28
SOUN Soundhound AI Inc. Class A Reduce -25.0% 0.44% −0.27
CAH Cardinal Health Inc. Reduce -85.2% 0.05% −0.26
VKTX Viking Therapeutics Inc. Reduce -8.3% 0.64% −0.25
COOP Mr Cooper Group Inc. Sold out 0.00% −0.23
NNDM Nano Dimension Ltd. - ADR Sold out 0.00% −0.17
SYM Symbotic Inc. Reduce -20.0% 0.52% −0.16
BSX Boston Scientific Corp. Sold out 0.00% −0.14
AZO AutoZone Inc. Sold out 0.00% −0.14
ORLY O'reilly Automotive Inc. Sold out 0.00% −0.13
UBER Uber Technologies Inc. Sold out 0.00% −0.12
MNST Monster Beverage Corp. Sold out 0.00% −0.11
MCD McDonald's Corp. Sold out 0.00% −0.11
LW Lamb Weston Holdings Inc. Sold out 0.00% −0.10
URI United Rentals Inc. Reduce -59.1% 0.08% −0.10
MDLZ Mondelez International Inc. Class A Sold out 0.00% −0.10
MGM MGM Resorts International Reduce -70.2% 0.05% −0.10
AAL American Airlines Group Inc. Sold out 0.00% −0.10
PCAR Paccar Inc. Reduce -31.1% 0.22% −0.09
SJM The JM Smucker Co. Sold out 0.00% −0.09
PHM Pultegroup Inc. Reduce -44.7% 0.14% −0.09
EWW iShares MSCI Mexico ETF Sold out 0.00% −0.08
HSY The Hershey Co. Sold out 0.00% −0.08
EPHE iShares MSCI Philippines ETF Sold out 0.00% −0.08
EWZ iShares MSCI Brazil ETF Sold out 0.00% −0.07
CI The Cigna Group Sold out 0.00% −0.07
ISRG Intuitive Surgical Inc. Reduce -33.3% 0.66% −0.07
APO Apollo Global Management Inc. Sold out 0.00% −0.07
MDT Medtronic PLC Reduce -14.6% 1.01% −0.06
HUM Humana Inc. Sold out 0.00% −0.06

Portfolio Buys Q1 2024 → Q2 2024

SRPT Sarepta Therapeutics Inc. Add +2688.1% 0.87% +0.85
QQQ Invesco QQQ Trust Series 1 Add +188.7% 1.15% +0.85
QQQM Invesco Nasdaq 100 ETF Add +188.3% 1.15% +0.84
AMPH Amphastar Pharmaceuticals Inc. New 0.74% +0.74
ACAD Acadia Pharmaceuticals Inc. Add +122.2% 1.20% +0.69
ENOV Enovis Corp. New 0.67% +0.67
CATX Perspective Therapeutics Inc. New 0.60% +0.60
NVDA Nvidia Corp. Add +783.7% 0.55% +0.51
CLDX Celldex Therapeutics Inc. Add +23.4% 1.29% +0.32
AVBP Arrivent Biopharma Inc. Add +3.6% 1.17% +0.28
JAZZ Jazz Pharmaceuticals PLC Add +29.4% 0.86% +0.25
FOLD Amicus Therapeutics Inc. Add +15.7% 1.48% +0.24
HIG Hartford Insurance Group Inc. Add +99.6% 0.34% +0.20
COST Costco Wholesale Corp. Add +70.6% 0.33% +0.20
SNY Sanofi-ADR Add +16.7% 0.63% +0.19
BMRN Biomarin Pharmaceutical Inc. Add +6.5% 1.00% +0.18
VALN Valneva SE - ADR Add +42.3% 0.48% +0.18
RSG Republic Services Inc. Add +86.2% 0.31% +0.17
JPM JPMorgan Chase & Co. Add +94.4% 0.28% +0.16
DVAX Dynavax Technologies Corp. Add +6.1% 1.07% +0.16
SYF Synchrony Financial Add +153.3% 0.22% +0.16
SHY iShares 1-3 Year Treasury Bo Add +28.6% 0.42% +0.15
APH Amphenol Corp. Class A New 0.14% +0.14
CTAS Cintas Corp. New 0.14% +0.14
TJX TJX Companies Inc. New 0.14% +0.14
BRO Brown & Brown Inc. New 0.13% +0.13
TMUS T-Mobile US Inc. New 0.13% +0.13
CIM Chimera Investment Corp. New 0.13% +0.13
IEI iShares 3-7 Year Treasury Bo Add +29.1% 0.36% +0.13
KGC Kinross Gold Corp. Add +143.4% 0.16% +0.12
ACGL Arch Capital Group Ltd. Add +23.9% 0.28% +0.11
IEF iShares 7-10 Year Treasury B Add +30.1% 0.29% +0.10
PR Permian Resources Corp. Class A Add +102.7% 0.18% +0.10
L Loews Corp. Add +30.2% 0.29% +0.10
EZA iShares MSCI South Africa Et New 0.10% +0.10
FXI iShares China Large-Cap ETF New 0.09% +0.09
THC Tenet Healthcare Corp. Add +66.2% 0.14% +0.09
DVA Davita Inc. Add +75.2% 0.15% +0.08
FTI Technipfmc PLC Add +97.0% 0.13% +0.08
TRGP Targa Resources Corp. New 0.08% +0.08
FANG Diamondback Energy Inc. New 0.07% +0.07
MET Metlife Inc. New 0.07% +0.07
MCK McKesson Corp. Add +53.7% 0.14% +0.07
AIZ Assurant Inc. Add +97.8% 0.13% +0.07
UHS Universal Health Services-B New 0.07% +0.07
WRB WR Berkley Corp. New 0.07% +0.07
AIG American International Group New 0.07% +0.07
CB Chubb Ltd. New 0.07% +0.07
APP AppLovin Corp. Class A New 0.06% +0.06
IMTX Immatics NV Add +14.3% 0.17% +0.06

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 259$118.0MGILD, VRTX, INVH, AZN, ROIV
Q1 2026 252$100.1MGILD, RPV, IWD, AZN, VRTX
Q4 2025 249$100.3MGILD, INVH, MBB, EEFT, VRTX
Q4 2024 209$100.2MLLY, UNH, JNJ, SHY, ABBV
Q3 2024 230$134.5MRITM, HRMY, LKFT, MRK, EFC
Q2 2024 217$135.8MUTHR, BCRX, RITM, PFE, HRMY
Q1 2024 228$165.8MPFE, RITM, HRMY, UTHR, PCRX