AlphaCentric Advisors LLC

In its 13F for Q1 2024 (holdings as of March 31, 2024, filed April 24, 2024), AlphaCentric Advisors LLC reported 228 stock positions worth $165.8 million. Its top holding was Pfizer (PFE) at 2.9% of the portfolio, followed by Rithm Capital (RITM, 2.8%) and Harmony Biosciences (HRMY, 2.5%). Compared with Q4 2023, it opened 38 new positions, sold out of 26, added to 43 and reduced 118. The biggest buy was a new position in United Therapeutics (UTHR) and the biggest sale an exit from Immunogen (IMGN).

Most Recent 13F
Q2 2026
Location
SAN JUAN, PR
CIK
0001913464
Portfolio Value
$165.8M (Q1 2024)
SEC Filing
0001162044-24-000403 ↗ filed Apr 24, 2024

Holdings Value

0$50.0M$100.0M$150.0M$200.0M Q1 2024: $165.8M $165.8M Q1 2024 Q2 2024: $135.8M Q2 2024 Q3 2024: $134.5M Q3 2024 Q4 2024: $100.2M Q4 2024 Q4 2025: $100.3M Q4 2025 Q1 2026: $100.1M Q1 2026 Q2 2026: $118.0M Q2 2026

Holdings 228 stocks · $165.8M

PFE Pfizer Inc. 2.93% 175,000 $4.9M Add +118.8%
RITM Rithm Capital Corp. 2.83% 420,966 $4.7M Add +5.0%
HRMY Harmony Biosciences Holdings 2.47% 122,000 $4.1M No change
UTHR United Therapeutics Corp. 2.22% 16,000 $3.7M New
PCRX Pacira Biosciences Inc. 2.07% 117,500 $3.4M No change
BCRX Biocryst Pharmaceuticals Inc. 2.07% 675,000 $3.4M No change
LKFT Lakefront Biotherapeutic-ADR filed as GALAPAGOS NV 2.04% 105,000 $3.4M No change
ARGX Argenx SE - ADR 1.90% 8,000 $3.1M Add +3.2%
TWO HARBORS INV CORP (TWO 6.25 01/15/26) 1.84% 3,205,000 $3.0M No change
NARI Inari Medical Inc. 1.82% 63,000 $3.0M Add +1160.0%
DCGO Docgo Inc. 1.58% 650,000 $2.6M Add +109.7%
ONC Beone Medicines Ltd.-ADR filed as BEIGENE LTD 1.58% 16,750 $2.6M Add +123.3%
EFC Ellington Financial Inc. 1.58% 221,602 $2.6M No change
AXSM Axsome Therapeutics Inc. 1.56% 32,500 $2.6M New
MTG Mgic Investment Corp. 1.54% 114,379 $2.6M Add +44.1%
QURE Uniqure NV 1.44% 460,000 $2.4M Add +9.3%
CHRS Coherus Oncology Inc. 1.44% 1,000,000 $2.4M No change
MIRM Mirum Pharmaceuticals Inc. 1.42% 94,000 $2.4M Add +88.0%
DX Dynex Capital Inc. 1.36% 181,492 $2.3M No change
URGN Urogen Pharma Ltd. 1.30% 143,898 $2.2M Reduce -7.2%
CORT Corcept Therapeutics Inc. 1.29% 85,000 $2.1M New
CATX Perspective Therapeutics Inc. 1.26% 1,756,756 $2.1M New
FOLD Amicus Therapeutics Inc. 1.24% 175,000 $2.1M Add +25.0%
EXAS Exact Sciences Corp. 1.21% 29,000 $2.0M New
PENNYMAC CORP (PMT 5.5 11/01/24) 1.17% 1,965,000 $1.9M No change
MFA Mfa Financial Inc. 1.15% 167,725 $1.9M Add +17.5%
RWT Redwood Trust Inc. 1.11% 288,343 $1.8M Add +96.7%
RPRX Royalty Pharma PLC Class A 1.10% 60,000 $1.8M Add +50.0%
CERE Cerevel Therapeutics Holding 1.08% 42,500 $1.8M Add +70.0%
MDT Medtronic PLC 1.08% 20,500 $1.8M No change
KPTI Karyopharm Therapeutics Inc. 1.02% 1,125,000 $1.7M No change
CLDX Celldex Therapeutics Inc. 0.97% 38,500 $1.6M New
RPV Invesco S&P 500 Pure Value E 0.95% 17,834 $1.6M New
STXS Stereotaxis Inc. 0.94% 600,000 $1.6M No change
IWD iShares Russell 1000 Value E 0.94% 8,671 $1.6M New
KALV Kalvista Pharmaceuticals Inc. 0.93% 130,000 $1.5M Reduce -5.1%
DVAX Dynavax Technologies Corp. 0.92% 122,500 $1.5M Add +22.5%
GSK GSK PLC-Spon ADR 0.91% 35,000 $1.5M No change
BCYC Bicycle Therapeutics PLC-ADR 0.90% 60,000 $1.5M New
AVBP Arrivent Biopharma Inc. 0.89% 83,000 $1.5M New
EMBC Embecta Corp. 0.89% 111,500 $1.5M Reduce -44.3%
VKTX Viking Therapeutics Inc. 0.89% 18,000 $1.5M New
ADAM Adamas Trust Inc. 0.87% 200,963 $1.4M No change
SNPS Synopsys Inc. 0.86% 2,500 $1.4M Add +19.1%
TRML Tourmaline Bio Inc. 0.84% 61,100 $1.4M New
ITCI Intra-Cellular Therapies Inc. 0.83% 20,000 $1.4M No change
VYNE THERAPEUTICS INC 0.82% 445,000 $1.4M Reduce -33.4%
BMRN Biomarin Pharmaceutical Inc. 0.82% 15,500 $1.4M Add +10.7%
ELS Equity Lifestyle Properties 0.80% 20,611 $1.3M No change
ACT Enact Holdings Inc. 0.80% 42,367 $1.3M No change
MITT TPG Mortgage Investment Trus 0.77% 208,879 $1.3M No change
PRCT Procept Biorobotics Corp. 0.75% 25,000 $1.2M New
IMVT Immunovant Inc. 0.74% 38,000 $1.2M No change
AVAV Aerovironment Inc. 0.74% 8,000 $1.2M New
RVNC Revance Therapeutics Inc. 0.73% 245,000 $1.2M Add +11.4%
ISRG Intuitive Surgical Inc. 0.72% 3,000 $1.2M Reduce -20.0%
GPCR Structure Therapeutics Inc. 0.71% 27,500 $1.2M Reduce -8.3%
SOUN Soundhound AI Inc. Class A 0.71% 200,000 $1.2M No change
SYM Symbotic Inc. 0.68% 25,000 $1.1M No change
CABA Cabaletta Bio Inc. 0.67% 65,000 $1.1M New
JAZZ Jazz Pharmaceuticals PLC 0.62% 8,500 $1.0M Reduce -19.1%
SGMT Sagimet Biosciences Inc. Class A 0.60% 185,000 $1.0M New
RWT HOLDINGS INC (RWT 5.75 10/01/25) filed as RWT HLDGS INC 0.59% 1,000,000 $970K Reduce -56.2%
NBIX Neurocrine Biosciences Inc. 0.58% 7,000 $965K New
ROIV Roivant Sciences Ltd. 0.57% 90,000 $949K Add +63.6%
DCPH Deciphera Pharmaceuticals Inc. 0.57% 60,000 $944K New
LUNR Intuitive Machines Inc. 0.57% 150,000 $938K New
VRNA Verona Pharma Ltd. 0.54% 56,000 $901K No change
RRX Regal Rexnord Corp. 0.54% 5,000 $901K New
ALNT Allient Inc. 0.54% 25,000 $892K New
ARAY Accuray Inc. 0.52% 350,000 $865K New
AGNC AGNC Investment Corp. 0.51% 84,646 $838K No change
ACAD Acadia Pharmaceuticals Inc. 0.50% 45,000 $832K Add +73.1%
SNY Sanofi-ADR 0.44% 15,000 $729K New
PTGX Protagonist Therapeutics Inc. 0.44% 25,000 $723K Reduce -16.7%
ONIT Onity Group Inc. filed as OCWEN FINL CORP 0.42% 25,567 $691K Reduce -9.3%
GMED Globus Medical Inc. Class A 0.40% 12,500 $671K New
DYN Dyne Therapeutics Inc. 0.34% 20,000 $568K New
PCAR Paccar Inc. 0.31% 4,146 $514K Reduce -10.2%
BBJP JPMorgan Betabuilders Japan 0.31% 8,747 $512K Reduce -8.4%
EWA iShares MSCI Australia ETF 0.31% 20,694 $510K Add +2.5%
CAH Cardinal Health Inc. 0.31% 4,546 $509K Reduce -10.0%
QQQ Invesco QQQ Trust Series 1 0.30% 1,128 $501K Reduce -78.0%
QQQM Invesco Nasdaq 100 ETF 0.30% 2,740 $501K Reduce -78.0%
AGMIT MERGER SUB LLC (MITT 6.75 09/15/24) 0.30% 500,000 $497K No change
VALN Valneva SE - ADR 0.30% 62,004 $495K Add +80.8%
NUVB Nuvation Bio Inc. 0.30% 135,000 $491K Reduce -70.0%
REDWOOD TRUST INC (RWT 7.75 06/15/27) 0.29% 500,000 $481K No change
MBB iShares MBS ETF 0.28% 5,000 $462K New
SHY iShares 1-3 Year Treasury Bo 0.27% 5,458 $446K Reduce -51.9%
AUPH Aurinia Pharmaceuticals Inc. 0.24% 80,000 $401K Add +60.0%
COOP Mr Cooper Group Inc. 0.23% 4,931 $384K Reduce -77.2%
DAL Delta Air Lines Inc. 0.23% 7,932 $380K Reduce -11.8%
PHM Pultegroup Inc. 0.23% 3,132 $378K Reduce -11.8%
IEI iShares 3-7 Year Treasury Bo 0.23% 3,242 $375K Reduce -29.0%
VYM Vanguard High DVD Yield ETF 0.23% 3,088 $374K Reduce -8.0%
REM iShares Mortgage Real Estate 0.22% 15,954 $371K Add +1.1%
CWB SS SPDR BB Conv Sec ETF 0.22% 4,972 $363K Reduce -5.2%
DWX State Street SPDR S&P Intern 0.22% 10,316 $363K Reduce -1.0%
PBP Invesco S&P 500 Buywrite ETF 0.22% 16,127 $363K Reduce -3.5%

Show all 228 holdings

Portfolio Sells Q4 2023 → Q1 2024

IMGN Immunogen Inc. Sold out 0.00% −2.54
WBA Walgreens Boots Alliance Inc. Sold out 0.00% −2.10
ABVX Abivax SA-ADR Sold out 0.00% −1.92
IRWD Ironwood Pharmaceuticals Inc. Sold out 0.00% −1.88
EMBC Embecta Corp. Reduce -44.3% 0.89% −1.65
AMLX Amylyx Pharmaceuticals Inc. Sold out 0.00% −1.49
QQQM Invesco Nasdaq 100 ETF Reduce -78.0% 0.30% −1.11
QQQ Invesco QQQ Trust Series 1 Reduce -78.0% 0.30% −1.11
RWT HOLDINGS INC (RWT 5.75 10/01/25) Reduce -56.2% 0.59% −0.85
VSTM Verastem Inc. Sold out 0.00% −0.82
KRTX Karuna Therapeutics Inc. Sold out 0.00% −0.74
COOP Mr Cooper Group Inc. Reduce -77.2% 0.23% −0.71
MBLY Mobileye Global Inc. Class A Sold out 0.00% −0.58
OMCL Omnicell Inc. Sold out 0.00% −0.51
IRTC Irhythm Holdings Inc. Sold out 0.00% −0.36
SHY iShares 1-3 Year Treasury Bo Reduce -51.9% 0.27% −0.36
HOS Hornbeck Offshore Services I Sold out 0.00% −0.34
GILD Gilead Sciences Inc. Reduce -58.8% 0.15% −0.31
URGN Urogen Pharma Ltd. Reduce -7.2% 1.30% −0.26
VTRS Viatris Inc. Sold out 0.00% −0.25
JAZZ Jazz Pharmaceuticals PLC Reduce -19.1% 0.62% −0.25
VYNE THERAPEUTICS INC Reduce -33.4% 0.82% −0.22
KALV Kalvista Pharmaceuticals Inc. Reduce -5.1% 0.93% −0.20
ONIT Onity Group Inc. Reduce -9.3% 0.42% −0.17
DPRO Draganfly Inc. Sold out 0.00% −0.16
NUVB Nuvation Bio Inc. Reduce -70.0% 0.30% −0.16
CBAY Cymabay Therapeutics Inc. Sold out 0.00% −0.16
NNDM Nano Dimension Ltd. - ADR Reduce -50.0% 0.17% −0.15
IEI iShares 3-7 Year Treasury Bo Reduce -29.0% 0.23% −0.13
ISRG Intuitive Surgical Inc. Reduce -20.0% 0.72% −0.13
GPCR Structure Therapeutics Inc. Reduce -8.3% 0.71% −0.11
MQY BlackRock Muniyield Quality Sold out 0.00% −0.04
HUM Humana Inc. Reduce -11.9% 0.06% −0.04
MHD BlackRock Muniholdings Fund Sold out 0.00% −0.04
MUC BlackRock Munihold Ca QLTY Sold out 0.00% −0.04
MUJ BlackRock Munihold NJ QLTY Sold out 0.00% −0.04
BLE BlackRock Muni Inc. TR II Sold out 0.00% −0.04
XMUIX BlackRock Municipal Income Sold out 0.00% −0.04
NOTE Fiscalnote Holdings Inc. Sold out 0.00% −0.04
CCL Carnival Corp. Reduce -11.9% 0.09% −0.04
CAH Cardinal Health Inc. Reduce -10.0% 0.31% −0.04
CWB SS SPDR BB Conv Sec ETF Reduce -5.2% 0.22% −0.03
EIM Eaton Vance Municipal Bond Sold out 0.00% −0.03
NMCO Nuveen Municipal Credit Opp Sold out 0.00% −0.03
NDMO Nuveen Dynamic Municipal Opp Sold out 0.00% −0.03
PMM Franklin Managed Municipal I Sold out 0.00% −0.03
EMB iShares JP Morgan Usd Emergi Reduce -3.3% 0.22% −0.03
DWX State Street SPDR S&P Intern Reduce -1.0% 0.22% −0.03
CHTR Charter Communications Inc. Class A Reduce -12.3% 0.04% −0.03
ASXC Asensus Surgical Inc. Reduce -16.7% 0.03% −0.03

Portfolio Buys Q4 2023 → Q1 2024

UTHR United Therapeutics Corp. New 2.22% +2.22
NARI Inari Medical Inc. Add +1160.0% 1.82% +1.61
AXSM Axsome Therapeutics Inc. New 1.56% +1.56
PFE Pfizer Inc. Add +118.8% 2.93% +1.38
CORT Corcept Therapeutics Inc. New 1.29% +1.29
CATX Perspective Therapeutics Inc. New 1.26% +1.26
EXAS Exact Sciences Corp. New 1.21% +1.21
CLDX Celldex Therapeutics Inc. New 0.97% +0.97
RPV Invesco S&P 500 Pure Value E New 0.95% +0.95
IWD iShares Russell 1000 Value E New 0.94% +0.94
BCYC Bicycle Therapeutics PLC-ADR New 0.90% +0.90
AVBP Arrivent Biopharma Inc. New 0.89% +0.89
VKTX Viking Therapeutics Inc. New 0.89% +0.89
TRML Tourmaline Bio Inc. New 0.84% +0.84
PRCT Procept Biorobotics Corp. New 0.75% +0.75
AVAV Aerovironment Inc. New 0.74% +0.74
ONC Beone Medicines Ltd.-ADR Add +123.3% 1.58% +0.67
CABA Cabaletta Bio Inc. New 0.67% +0.67
SGMT Sagimet Biosciences Inc. Class A New 0.60% +0.60
NBIX Neurocrine Biosciences Inc. New 0.58% +0.58
DCPH Deciphera Pharmaceuticals Inc. New 0.57% +0.57
LUNR Intuitive Machines Inc. New 0.57% +0.57
RRX Regal Rexnord Corp. New 0.54% +0.54
ALNT Allient Inc. New 0.54% +0.54
ARAY Accuray Inc. New 0.52% +0.52
MTG Mgic Investment Corp. Add +44.1% 1.54% +0.51
SNY Sanofi-ADR New 0.44% +0.44
MIRM Mirum Pharmaceuticals Inc. Add +88.0% 1.42% +0.43
DCGO Docgo Inc. Add +109.7% 1.58% +0.42
GMED Globus Medical Inc. Class A New 0.40% +0.40
RWT Redwood Trust Inc. Add +96.7% 1.11% +0.38
CERE Cerevel Therapeutics Holding Add +70.0% 1.08% +0.37
RPRX Royalty Pharma PLC Class A Add +50.0% 1.10% +0.34
DYN Dyne Therapeutics Inc. New 0.34% +0.34
MBB iShares MBS ETF New 0.28% +0.28
ROIV Roivant Sciences Ltd. Add +63.6% 0.57% +0.16
AZO AutoZone Inc. New 0.14% +0.14
SNPS Synopsys Inc. Add +19.1% 0.86% +0.14
HCA HCA Healthcare Inc. New 0.13% +0.13
CBOE Cboe Global Markets Inc. New 0.12% +0.12
IMTX Immatics NV New 0.11% +0.11
IEF iShares 7-10 Year Treasury B Add +140.3% 0.18% +0.10
EPHE iShares MSCI Philippines ETF New 0.08% +0.08
EWM iShares MSCI Malaysia ETF New 0.07% +0.07
MFA Mfa Financial Inc. Add +17.5% 1.15% +0.07
BNY Bank of New York Mellon Corp. New 0.06% +0.06
ANET Arista Networks Inc. New 0.06% +0.06
VRDN Viridian Therapeutics Inc. New 0.06% +0.06
VALN Valneva SE - ADR Add +80.8% 0.30% +0.06
EIDO iShares MSCI Indonesia ETF New 0.05% +0.05

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 259$118.0MGILD, VRTX, INVH, AZN, ROIV
Q1 2026 252$100.1MGILD, RPV, IWD, AZN, VRTX
Q4 2025 249$100.3MGILD, INVH, MBB, EEFT, VRTX
Q4 2024 209$100.2MLLY, UNH, JNJ, SHY, ABBV
Q3 2024 230$134.5MRITM, HRMY, LKFT, MRK, EFC
Q2 2024 217$135.8MUTHR, BCRX, RITM, PFE, HRMY
Q1 2024 228$165.8MPFE, RITM, HRMY, UTHR, PCRX