AlphaCentric Advisors LLC
In its 13F for Q3 2024 (holdings as of September 30, 2024, filed October 30, 2024), AlphaCentric Advisors LLC reported 230 stock positions worth $134.5 million. Its top holding was Rithm Capital (RITM) at 3.2% of the portfolio, followed by Harmony Biosciences (HRMY, 2.9%) and Lakefront Biotherapeutic-ADR (LKFT, 2.3%). Compared with Q2 2024, it opened 28 new positions, sold out of 15, added to 29 and reduced 140. The biggest buy was a new position in Merck (MRK) and the biggest sale an exit from Biocryst Pharmaceuticals (BCRX).
- Most Recent 13F
- Q2 2026
- Location
- SAN JUAN, PR
- CIK
- 0001913464
- Portfolio Value
- $134.5M (Q3 2024)
- SEC Filing
- 0001162044-24-001177 ↗ filed Oct 30, 2024
Holdings Value
Holdings 230 stocks · $134.5M
| RITM Rithm Capital Corp. | 3.21% | 380,966 | $4.3M | No change |
| HRMY Harmony Biosciences Holdings | 2.88% | 97,000 | $3.9M | Reduce -20.5% |
| LKFT Lakefront Biotherapeutic-ADR filed as GALAPAGOS NV | 2.32% | 108,500 | $3.1M | No change |
| MRK Merck & Co. Inc. | 2.03% | 24,000 | $2.7M | New |
| EFC Ellington Financial Inc. | 1.93% | 201,602 | $2.6M | No change |
| NBIX Neurocrine Biosciences Inc. | 1.93% | 22,500 | $2.6M | Add +221.4% |
| MTG Mgic Investment Corp. | 1.89% | 99,379 | $2.5M | Reduce -13.1% |
| ARGX Argenx SE - ADR | 1.81% | 4,500 | $2.4M | Reduce -37.9% |
| INDV Indivior Ltd. | 1.76% | 242,500 | $2.4M | New |
| DX Dynex Capital Inc. | 1.72% | 181,492 | $2.3M | No change |
| BMRN Biomarin Pharmaceutical Inc. | 1.70% | 32,500 | $2.3M | Add +97.0% |
| SRPT Sarepta Therapeutics Inc. | 1.67% | 18,000 | $2.2M | Add +140.0% |
| DVAX Dynavax Technologies Corp. | 1.67% | 201,500 | $2.2M | Add +55.0% |
| UTHR United Therapeutics Corp. | 1.67% | 6,250 | $2.2M | Reduce -56.9% |
| RWT Redwood Trust Inc. | 1.66% | 288,343 | $2.2M | No change |
| FOLD Amicus Therapeutics Inc. | 1.63% | 205,000 | $2.2M | Add +1.2% |
| MFA Mfa Financial Inc. | 1.59% | 167,725 | $2.1M | No change |
| ATEC Alphatec Holdings Inc. | 1.53% | 370,000 | $2.1M | New |
| EXAS Exact Sciences Corp. | 1.52% | 30,000 | $2.0M | No change |
| QQQ Invesco QQQ Trust Series 1 | 1.52% | 4,182 | $2.0M | Add +28.4% |
| QQQM Invesco Nasdaq 100 ETF | 1.52% | 10,158 | $2.0M | Add +28.6% |
| RPRX Royalty Pharma PLC Class A | 1.42% | 67,500 | $1.9M | Add +12.5% |
| MIRM Mirum Pharmaceuticals Inc. | 1.30% | 45,000 | $1.8M | Reduce -29.7% |
| JAZZ Jazz Pharmaceuticals PLC | 1.28% | 15,500 | $1.7M | Add +40.9% |
| MITT TPG Mortgage Investment Trus | 1.17% | 208,879 | $1.6M | No change |
| ACT Enact Holdings Inc. | 1.14% | 42,367 | $1.5M | No change |
| ELS Equity Lifestyle Properties | 1.09% | 20,611 | $1.5M | No change |
| ITCI Intra-Cellular Therapies Inc. | 1.09% | 20,000 | $1.5M | No change |
| AMPH Amphastar Pharmaceuticals Inc. | 1.08% | 30,000 | $1.5M | Add +20.0% |
| VRNA Verona Pharma Ltd. | 1.07% | 50,000 | $1.4M | Reduce -10.7% |
| GSK GSK PLC-Spon ADR | 1.06% | 35,000 | $1.4M | No change |
| APLS Apellis Pharmaceuticals Inc. | 1.02% | 47,500 | $1.4M | New |
| ADAM Adamas Trust Inc. | 0.95% | 200,963 | $1.3M | No change |
| RVNC Revance Therapeutics Inc. | 0.95% | 245,000 | $1.3M | No change |
| ONC Beone Medicines Ltd.-ADR filed as BEIGENE LTD | 0.92% | 5,500 | $1.2M | Reduce -63.3% |
| STXS Stereotaxis Inc. | 0.91% | 600,000 | $1.2M | No change |
| ENOV Enovis Corp. | 0.88% | 27,500 | $1.2M | Add +37.5% |
| TWO HARBORS INV CORP (TWO 6.25 01/15/26) | 0.88% | 1,205,000 | $1.2M | No change |
| ROIV Roivant Sciences Ltd. | 0.86% | 100,000 | $1.2M | Add +13.6% |
| GPCR Structure Therapeutics Inc. | 0.85% | 26,000 | $1.1M | No change |
| TAK Takeda Pharmaceutic-SP ADR | 0.85% | 80,000 | $1.1M | New |
| PTGX Protagonist Therapeutics Inc. | 0.84% | 25,000 | $1.1M | No change |
| CATX Perspective Therapeutics Inc. | 0.79% | 80,000 | $1.1M | Reduce -2.4% |
| CLDX Celldex Therapeutics Inc. | 0.76% | 30,000 | $1.0M | Reduce -36.8% |
| PFE Pfizer Inc. | 0.75% | 35,000 | $1.0M | Reduce -75.0% |
| SNY Sanofi-ADR | 0.75% | 17,500 | $1.0M | No change |
| IMVT Immunovant Inc. | 0.74% | 35,000 | $998K | Reduce -4.1% |
| LNTH Lantheus Holdings Inc. | 0.73% | 9,000 | $988K | New |
| PENNYMAC CORP (PMT 5.5 11/01/24) | 0.71% | 965,000 | $961K | No change |
| AXSM Axsome Therapeutics Inc. | 0.70% | 10,500 | $944K | Reduce -30.0% |
| KPTI Karyopharm Therapeutics Inc. | 0.69% | 1,125,000 | $934K | No change |
| AGNC AGNC Investment Corp. | 0.66% | 84,646 | $885K | No change |
| BCYC Bicycle Therapeutics PLC-ADR | 0.63% | 37,500 | $849K | Reduce -37.5% |
| ONIT Onity Group Inc. | 0.61% | 25,567 | $817K | No change |
| PEN Penumbra Inc. | 0.58% | 4,000 | $777K | New |
| NVDA Nvidia Corp. | 0.54% | 5,981 | $726K | Reduce -0.5% |
| VALN Valneva SE - ADR | 0.53% | 118,000 | $717K | Add +33.7% |
| NUVL Nuvalent Inc. Class A | 0.53% | 7,000 | $716K | New |
| MLTX Moonlake Immunotherapeutics | 0.52% | 14,000 | $706K | New |
| CYTK Cytokinetics Inc. | 0.49% | 12,500 | $660K | New |
| PRCT Procept Biorobotics Corp. | 0.48% | 8,000 | $641K | Reduce -20.0% |
| ARAY Accuray Inc. | 0.47% | 350,000 | $630K | No change |
| ACAD Acadia Pharmaceuticals Inc. | 0.46% | 40,000 | $615K | Reduce -60.0% |
| ISRG Intuitive Surgical Inc. | 0.46% | 1,250 | $614K | Reduce -37.5% |
| SYM Symbotic Inc. | 0.45% | 25,000 | $610K | Add +25.0% |
| CGNX Cognex Corp. | 0.45% | 15,000 | $608K | New |
| ROK Rockwell Automation Inc. | 0.45% | 2,250 | $604K | New |
| SOUN Soundhound AI Inc. Class A | 0.43% | 125,000 | $583K | Reduce -16.7% |
| HIG Hartford Insurance Group Inc. | 0.39% | 4,451 | $523K | Reduce -4.3% |
| EWA iShares MSCI Australia ETF | 0.39% | 19,248 | $522K | Reduce -3.0% |
| SGMT Sagimet Biosciences Inc. Class A | 0.38% | 185,000 | $512K | No change |
| EMBC Embecta Corp. | 0.38% | 36,000 | $508K | Reduce -36.3% |
| SNPS Synopsys Inc. | 0.38% | 1,000 | $506K | Reduce -50.0% |
| VYNE THERAPEUTICS INC | 0.38% | 268,485 | $505K | Reduce -13.5% |
| AVAV Aerovironment Inc. | 0.37% | 2,500 | $501K | Reduce -20.6% |
| APGE Apogee Therapeutics Inc. | 0.37% | 8,500 | $499K | New |
| BBJP JPMorgan Betabuilders Japan | 0.37% | 8,363 | $496K | Reduce -3.0% |
| KROS Keros Therapeutics Inc. | 0.35% | 8,000 | $465K | New |
| MDT Medtronic PLC | 0.33% | 5,000 | $450K | Reduce -71.4% |
| COST Costco Wholesale Corp. | 0.33% | 499 | $442K | Reduce -6.5% |
| RSG Republic Services Inc. | 0.30% | 2,020 | $406K | Reduce -6.4% |
| ACGL Arch Capital Group Ltd. | 0.30% | 3,587 | $401K | Reduce -3.3% |
| L Loews Corp. | 0.29% | 4,953 | $392K | Reduce -5.2% |
| JPM JPMorgan Chase & Co. | 0.28% | 1,800 | $380K | Reduce -4.5% |
| IEF iShares 7-10 Year Treasury B | 0.28% | 3,823 | $375K | Reduce -8.7% |
| IEI iShares 3-7 Year Treasury Bo | 0.28% | 3,126 | $374K | Reduce -25.3% |
| SHY iShares 1-3 Year Treasury Bo | 0.28% | 4,482 | $373K | Reduce -36.1% |
| CWB SS SPDR BB Conv Sec ETF | 0.28% | 4,834 | $370K | Reduce -1.9% |
| PFF iShares Preferred & Income S | 0.28% | 11,136 | $370K | Reduce -0.2% |
| EMHY iShares J.P. Morgan Em High | 0.27% | 9,401 | $367K | Reduce -0.5% |
| EMB iShares JP Morgan Usd Emergi | 0.27% | 3,908 | $366K | Reduce -1.6% |
| INSM Insmed Inc. | 0.27% | 5,000 | $365K | New |
| VYM Vanguard High DVD Yield ETF | 0.27% | 2,815 | $361K | Reduce -4.1% |
| PBP Invesco S&P 500 Buywrite ETF | 0.27% | 15,794 | $361K | Reduce -1.4% |
| DWX State Street SPDR S&P Intern | 0.27% | 9,375 | $360K | Reduce -5.9% |
| DYN Dyne Therapeutics Inc. | 0.27% | 10,000 | $359K | Reduce -50.0% |
| BKLN Invesco Senior Loan ETF | 0.27% | 17,016 | $358K | Add +2.0% |
| REM iShares Mortgage Real Estate | 0.26% | 14,926 | $354K | Add +5.3% |
| DAL Delta Air Lines Inc. | 0.26% | 6,951 | $353K | Reduce -3.0% |
| AVBP Arrivent Biopharma Inc. | 0.26% | 15,000 | $353K | Reduce -82.6% |
Portfolio Sells Q2 2024 → Q3 2024
| BCRX Biocryst Pharmaceuticals Inc. | Sold out | 0.00% | −3.07 |
| PCRX Pacira Biosciences Inc. | Sold out | 0.00% | −2.48 |
| PFE Pfizer Inc. | Reduce -75.0% | 0.75% | −2.13 |
| UTHR United Therapeutics Corp. | Reduce -56.9% | 1.67% | −1.74 |
| QURE Uniqure NV | Sold out | 0.00% | −1.52 |
| DCGO Docgo Inc. | Sold out | 0.00% | −1.48 |
| CERE Cerevel Therapeutics Holding | Sold out | 0.00% | −1.28 |
| CHRS Coherus Oncology Inc. | Reduce -67.0% | 0.26% | −1.02 |
| AVBP Arrivent Biopharma Inc. | Reduce -82.6% | 0.26% | −0.91 |
| ACAD Acadia Pharmaceuticals Inc. | Reduce -60.0% | 0.46% | −0.74 |
| RWT HOLDINGS INC (RWT 5.75 10/01/25) | Sold out | 0.00% | −0.72 |
| MDT Medtronic PLC | Reduce -71.4% | 0.33% | −0.68 |
| ONC Beone Medicines Ltd.-ADR | Reduce -63.3% | 0.92% | −0.66 |
| TRML Tourmaline Bio Inc. | Reduce -92.7% | 0.11% | −0.61 |
| CLDX Celldex Therapeutics Inc. | Reduce -36.8% | 0.76% | −0.54 |
| NARI Inari Medical Inc. | Sold out | 0.00% | −0.53 |
| SNPS Synopsys Inc. | Reduce -50.0% | 0.38% | −0.50 |
| ARGX Argenx SE - ADR | Reduce -37.9% | 1.81% | −0.48 |
| VKTX Viking Therapeutics Inc. | Reduce -78.8% | 0.16% | −0.48 |
| CABA Cabaletta Bio Inc. | Sold out | 0.00% | −0.39 |
| REDWOOD TRUST INC (RWT 7.75 06/15/27) | Sold out | 0.00% | −0.36 |
| IWD iShares Russell 1000 Value E | Sold out | 0.00% | −0.35 |
| RPV Invesco S&P 500 Pure Value E | Sold out | 0.00% | −0.35 |
| AUPH Aurinia Pharmaceuticals Inc. | Sold out | 0.00% | −0.34 |
| MIRM Mirum Pharmaceuticals Inc. | Reduce -29.7% | 1.30% | −0.31 |
| BCYC Bicycle Therapeutics PLC-ADR | Reduce -37.5% | 0.63% | −0.26 |
| DYN Dyne Therapeutics Inc. | Reduce -50.0% | 0.27% | −0.25 |
| ISRG Intuitive Surgical Inc. | Reduce -37.5% | 0.46% | −0.20 |
| AXSM Axsome Therapeutics Inc. | Reduce -30.0% | 0.70% | −0.19 |
| SHY iShares 1-3 Year Treasury Bo | Reduce -36.1% | 0.28% | −0.14 |
| EMBC Embecta Corp. | Reduce -36.3% | 0.38% | −0.14 |
| TUR iShares MSCI Turkey ETF | Sold out | 0.00% | −0.09 |
| IEI iShares 3-7 Year Treasury Bo | Reduce -25.3% | 0.28% | −0.08 |
| VYNE THERAPEUTICS INC | Reduce -13.5% | 0.38% | −0.08 |
| AVAV Aerovironment Inc. | Reduce -20.6% | 0.37% | −0.05 |
| EWY iShares MSCI South Korea ETF | Reduce -44.1% | 0.05% | −0.04 |
| PR Permian Resources Corp. Class A | Reduce -1.3% | 0.15% | −0.03 |
| MCK McKesson Corp. | Reduce -6.7% | 0.11% | −0.03 |
| KALV Kalvista Pharmaceuticals Inc. | Sold out | 0.00% | −0.02 |
| VTYX Ventyx Biosciences Inc. | Sold out | 0.00% | −0.02 |
| SMCI Super Micro Computer Inc. | Reduce -3.9% | 0.02% | −0.02 |
| CPRT Copart Inc. | Reduce -6.7% | 0.14% | −0.01 |
| PCAR Paccar Inc. | Reduce -3.1% | 0.20% | −0.01 |
| F Ford Motor Co. | Reduce -2.3% | 0.06% | −0.01 |
| APH Amphenol Corp. Class A | Reduce -6.4% | 0.13% | −0.01 |
| FANG Diamondback Energy Inc. | Reduce -2.6% | 0.06% | −0.01 |
| ROP Roper Technologies Inc. | Reduce -6.8% | 0.14% | −0.01 |
| IEF iShares 7-10 Year Treasury B | Reduce -8.7% | 0.28% | −0.01 |
| ESTC Elastic NV | Reduce -2.9% | 0.02% | −0.01 |
| CRWD CrowdStrike Holdings Inc. Class A | Reduce -2.0% | 0.02% | −0.01 |
Portfolio Buys Q2 2024 → Q3 2024
| MRK Merck & Co. Inc. | New | 2.03% | +2.03 |
| INDV Indivior Ltd. | New | 1.76% | +1.76 |
| ATEC Alphatec Holdings Inc. | New | 1.53% | +1.53 |
| NBIX Neurocrine Biosciences Inc. | Add +221.4% | 1.93% | +1.22 |
| APLS Apellis Pharmaceuticals Inc. | New | 1.02% | +1.02 |
| TAK Takeda Pharmaceutic-SP ADR | New | 0.85% | +0.85 |
| SRPT Sarepta Therapeutics Inc. | Add +140.0% | 1.67% | +0.80 |
| LNTH Lantheus Holdings Inc. | New | 0.73% | +0.73 |
| BMRN Biomarin Pharmaceutical Inc. | Add +97.0% | 1.70% | +0.70 |
| DVAX Dynavax Technologies Corp. | Add +55.0% | 1.67% | +0.59 |
| PEN Penumbra Inc. | New | 0.58% | +0.58 |
| NUVL Nuvalent Inc. Class A | New | 0.53% | +0.53 |
| MLTX Moonlake Immunotherapeutics | New | 0.52% | +0.52 |
| CYTK Cytokinetics Inc. | New | 0.49% | +0.49 |
| CGNX Cognex Corp. | New | 0.45% | +0.45 |
| ROK Rockwell Automation Inc. | New | 0.45% | +0.45 |
| JAZZ Jazz Pharmaceuticals PLC | Add +40.9% | 1.28% | +0.42 |
| APGE Apogee Therapeutics Inc. | New | 0.37% | +0.37 |
| QQQM Invesco Nasdaq 100 ETF | Add +28.6% | 1.52% | +0.37 |
| QQQ Invesco QQQ Trust Series 1 | Add +28.4% | 1.52% | +0.37 |
| AMPH Amphastar Pharmaceuticals Inc. | Add +20.0% | 1.08% | +0.35 |
| KROS Keros Therapeutics Inc. | New | 0.35% | +0.35 |
| INSM Insmed Inc. | New | 0.27% | +0.27 |
| RPRX Royalty Pharma PLC Class A | Add +12.5% | 1.42% | +0.25 |
| CDNS Cadence Design SYS Inc. | New | 0.25% | +0.25 |
| VERA Vera Therapeutics Inc. | New | 0.25% | +0.25 |
| JSPR Jasper Therapeutics Inc. | New | 0.24% | +0.24 |
| ENOV Enovis Corp. | Add +37.5% | 0.88% | +0.21 |
| KNSA Kiniksa Pharmaceuticals Inte | New | 0.21% | +0.21 |
| DXCM Dexcom Inc. | New | 0.21% | +0.21 |
| ROIV Roivant Sciences Ltd. | Add +13.6% | 0.86% | +0.17 |
| MYO Myomo Inc. | New | 0.15% | +0.15 |
| FOLD Amicus Therapeutics Inc. | Add +1.2% | 1.63% | +0.15 |
| VRDN Viridian Therapeutics Inc. | Add +20.0% | 0.25% | +0.13 |
| RKLB Rocket Lab USA Inc. | New | 0.11% | +0.11 |
| THD iShares MSCI Thailand ETF | New | 0.10% | +0.10 |
| EPHE iShares MSCI Philippines ETF | New | 0.10% | +0.10 |
| EIDO iShares MSCI Indonesia ETF | New | 0.10% | +0.10 |
| PGNY Progyny Inc. | New | 0.09% | +0.09 |
| LUNR Intuitive Machines Inc. | New | 0.09% | +0.09 |
| WIP State Street SPDR Ftse Inter | New | 0.08% | +0.08 |
| VALN Valneva SE - ADR | Add +33.7% | 0.53% | +0.06 |
| IMTX Immatics NV | Add +25.0% | 0.21% | +0.04 |
| REM iShares Mortgage Real Estate | Add +5.3% | 0.26% | +0.03 |
| FXI iShares China Large-Cap ETF | Add +2.4% | 0.11% | +0.02 |
| EPU iShares MSCI Peru and Global | Add +9.7% | 0.10% | +0.02 |
| EWP iShares MSCI Spain ETF | Add +1.1% | 0.09% | +0.01 |
| EWQ iShares MSCI France ETF | Add +6.4% | 0.08% | +0.01 |
| EWI iShares MSCI Italy ETF | Add +1.7% | 0.08% | +0.01 |
| EWD iShares MSCI Sweden ETF | Add +1.2% | 0.08% | +0.01 |
All Filings
| Quarter | Positions | 13F Reported Value | Top Holdings |
|---|---|---|---|
| Q2 2026 | 259 | $118.0M | GILD, VRTX, INVH, AZN, ROIV |
| Q1 2026 | 252 | $100.1M | GILD, RPV, IWD, AZN, VRTX |
| Q4 2025 | 249 | $100.3M | GILD, INVH, MBB, EEFT, VRTX |
| Q4 2024 | 209 | $100.2M | LLY, UNH, JNJ, SHY, ABBV |
| Q3 2024 | 230 | $134.5M | RITM, HRMY, LKFT, MRK, EFC |
| Q2 2024 | 217 | $135.8M | UTHR, BCRX, RITM, PFE, HRMY |
| Q1 2024 | 228 | $165.8M | PFE, RITM, HRMY, UTHR, PCRX |