Atlas Venture Life Science Advisors, LLC

In its 13F for Q3 2024 (holdings as of September 30, 2024, filed November 13, 2024), Atlas Venture Life Science Advisors, LLC reported 14 stock positions worth $1.1 billion. Its top holding was Dyne Therapeutics (DYN) at 26.7% of the portfolio, followed by Kymera Therapeutics (KYMR, 21.5%) and Third Harmonic Bio (THRD, 13.7%). Compared with Q2 2024, it sold out of 1 and reduced 3. The biggest sale was an exit from Replimune (REPL).

Most Recent 13F
Q2 2026
Location
CAMBRIDGE, MA
CIK
0001917529
Portfolio Value
$1.1B (Q3 2024)
SEC Filing
0001104659-24-116967 ↗ filed Nov 13, 2024

Holdings Value

0$500.0M$1.0B$1.5B Q1 2024: $1.1B Q1 2024 Q2 2024: $949.6M Q2 2024 Q3 2024: $1.1B $1.1B Q3 2024 Q4 2024: $819.7M Q4 2024 Q1 2025: $521.8M Q1 2025 Q2 2025: $662.4M Q2 2025 Q3 2025: $752.6M Q3 2025 Q4 2025: $865.2M Q4 2025 Q1 2026: $790.0M Q1 2026 Q2 2026: $881.3M Q2 2026

Holdings 14 stocks · $1.1B
DYN Dyne Therapeutics Inc. 26.71% 8,020,136 $288.1M No change
KYMR Kymera Therapeutics Inc. 21.48% 4,896,462 $231.7M Reduce -8.5%
THRD Third Harmonic Bio Inc. 13.70% 10,907,859 $147.8M No change
IRON Disc Medicine Inc. 11.43% 2,509,456 $123.3M No change
QTTB Q32 Bio Inc. 8.65% 2,092,106 $93.3M No change
DAWN Day One Biopharmaceuticals I 8.30% 6,430,257 $89.6M No change
KRRO Korro Bio Inc. 3.52% 1,137,149 $38.0M No change
GBIO Generation Bio Co. 1.90% 8,279,484 $20.5M No change
VIGL Vigil Neuroscience Inc. 1.84% 5,836,874 $19.8M No change
TECX Tectonic Therapeutic Inc. 1.06% 378,447 $11.5M No change
IKENA ONCOLOGY INC 0.80% 5,018,178 $8.7M No change
AEROVATE THERAPEUTICS INC 0.35% 1,799,232 $3.8M No change
DNTH Dianthus Therapeutics Inc. 0.20% 76,979 $2.1M Reduce -43.8%
SPRO Spero Therapeutics Inc. 0.05% 402,885 $540K Reduce -24.7%

Portfolio Sells Q2 2024 → Q3 2024
REPL Replimune Group Inc. Sold out 0.00% −1.99
DNTH Dianthus Therapeutics Inc. Reduce -43.8% 0.20% −0.18
SPRO Spero Therapeutics Inc. Reduce -24.7% 0.05% −0.02
KYMR Kymera Therapeutics Inc. Reduce -8.5% 21.48% +4.67

Portfolio Buys Q2 2024 → Q3 2024
None this quarter.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 7$881.3MKYMR, DYN, SION, KLRA, IRON
Q1 2026 6$790.0MKYMR, DYN, SION, IRON, QTTB
Q4 2025 8$865.2MKYMR, DYN, SION, IRON, DAWN
Q3 2025 9$752.6MKYMR, IRON, DYN, SION, KRRO
Q2 2025 11$662.4MKYMR, IRON, DYN, SION, THRD
Q1 2025 13$521.8MKYMR, IRON, DYN, DAWN, SION
Q4 2024 13$819.7MKYMR, DYN, IRON, THRD, DAWN
Q3 2024 14$1.1BDYN, KYMR, THRD, IRON, QTTB
Q2 2024 15$949.6MDYN, KYMR, THRD, IRON, DAWN
Q1 2024 16$1.1BDYN, KYMR, IRON, DAWN, THRD