Atlas Venture Life Science Advisors, LLC

In its 13F for Q4 2024 (holdings as of December 31, 2024, filed February 6, 2025), Atlas Venture Life Science Advisors, LLC reported 13 stock positions worth $819.7 million. Its top holding was Kymera Therapeutics (KYMR) at 24.0% of the portfolio, followed by Dyne Therapeutics (DYN, 23.1%) and Disc Medicine (IRON, 19.4%). Compared with Q3 2024, it sold out of 1 and reduced 4. The biggest sale was Dyne Therapeutics (DYN, shares −0%).

Most Recent 13F
Q2 2026
Location
CAMBRIDGE, MA
CIK
0001917529
Portfolio Value
$819.7M (Q4 2024)
SEC Filing
0001104659-25-010152 ↗ filed Feb 6, 2025

Holdings Value

0$500.0M$1.0B$1.5B Q1 2024: $1.1B Q1 2024 Q2 2024: $949.6M Q2 2024 Q3 2024: $1.1B Q3 2024 Q4 2024: $819.7M $819.7M Q4 2024 Q1 2025: $521.8M Q1 2025 Q2 2025: $662.4M Q2 2025 Q3 2025: $752.6M Q3 2025 Q4 2025: $865.2M Q4 2025 Q1 2026: $790.0M Q1 2026 Q2 2026: $881.3M Q2 2026

Holdings 13 stocks · $819.7M
KYMR Kymera Therapeutics Inc. 24.03% 4,896,462 $197.0M No change
DYN Dyne Therapeutics Inc. 23.05% 8,019,354 $188.9M Reduce -0.0%
IRON Disc Medicine Inc. 19.41% 2,509,456 $159.1M No change
THRD Third Harmonic Bio Inc. 13.06% 10,402,286 $107.0M Reduce -4.6%
DAWN Day One Biopharmaceuticals I 9.94% 6,430,257 $81.5M No change
KRRO Korro Bio Inc. 5.28% 1,137,149 $43.3M No change
VIGL Vigil Neuroscience Inc. 1.21% 5,836,874 $9.9M No change
GBIO Generation Bio Co. 1.07% 8,279,484 $8.8M No change
IKENA ONCOLOGY INC 1.00% 5,018,178 $8.2M No change
QTTB Q32 Bio Inc. 0.88% 2,092,106 $7.2M No change
AEROVATE THERAPEUTICS INC 0.58% 1,799,232 $4.8M No change
TECX Tectonic Therapeutic Inc. 0.44% 78,447 $3.6M Reduce -79.3%
SPRO Spero Therapeutics Inc. 0.04% 305,255 $314K Reduce -24.2%

Portfolio Sells Q3 2024 → Q4 2024
DYN Dyne Therapeutics Inc. Reduce -0.0% 23.05% −3.66
THRD Third Harmonic Bio Inc. Reduce -4.6% 13.06% −0.64
TECX Tectonic Therapeutic Inc. Reduce -79.3% 0.44% −0.62
DNTH Dianthus Therapeutics Inc. Sold out 0.00% −0.20
SPRO Spero Therapeutics Inc. Reduce -24.2% 0.04% −0.01

Portfolio Buys Q3 2024 → Q4 2024
None this quarter.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 7$881.3MKYMR, DYN, SION, KLRA, IRON
Q1 2026 6$790.0MKYMR, DYN, SION, IRON, QTTB
Q4 2025 8$865.2MKYMR, DYN, SION, IRON, DAWN
Q3 2025 9$752.6MKYMR, IRON, DYN, SION, KRRO
Q2 2025 11$662.4MKYMR, IRON, DYN, SION, THRD
Q1 2025 13$521.8MKYMR, IRON, DYN, DAWN, SION
Q4 2024 13$819.7MKYMR, DYN, IRON, THRD, DAWN
Q3 2024 14$1.1BDYN, KYMR, THRD, IRON, QTTB
Q2 2024 15$949.6MDYN, KYMR, THRD, IRON, DAWN
Q1 2024 16$1.1BDYN, KYMR, IRON, DAWN, THRD