| VRTX Vertex Pharmaceuticals Inc. | 7.25% | 681,908 | $304.5M | Add +0.1% |
| ARGX Argenx SE - ADR | 5.44% | 313,000 | $228.6M | Reduce -32.2% |
| REGN Regeneron Pharmaceuticals | 5.12% | 278,674 | $215.3M | Add +1900.8% |
| SRRK Scholar Rock Holding Corp. | 4.19% | 3,584,573 | $176.2M | Reduce -11.6% |
| GILD Gilead Sciences Inc. | 3.88% | 1,169,879 | $163.0M | Add +2117.7% |
| RVMD Revolution Medicines Inc. | 3.57% | 1,544,456 | $150.2M | Reduce -69.2% |
| IONS Ionis Pharmaceuticals Inc. | 3.25% | 1,818,665 | $136.6M | Reduce -62.1% |
| ISRG Intuitive Surgical Inc. | 3.14% | 286,654 | $132.1M | Reduce -11.0% |
| VRDN Viridian Therapeutics Inc. | 3.13% | 6,726,144 | $131.6M | Add +54.3% |
| KRYS Krystal Biotech Inc. | 2.96% | 481,785 | $124.5M | Add +17.4% |
| CRNX Crinetics Pharmaceuticals Inc. | 2.84% | 3,280,000 | $119.1M | Add +81088.1% |
| ABT Abbott Laboratories | 2.81% | 1,151,635 | $118.2M | Reduce -12.6% |
| NUVL Nuvalent Inc. Class A | 2.57% | 1,053,268 | $107.9M | Add +1.5% |
| AMGN Amgen Inc. | 2.47% | 295,358 | $103.9M | Add +1497.5% |
| BSX Boston Scientific Corp. | 2.19% | 1,466,894 | $92.0M | Reduce -5.9% |
| ELVN Enliven Therapeutics Inc. | 2.17% | 2,320,867 | $91.0M | New |
| IMCR Immunocore Holdings PLC-ADR | 2.01% | 2,796,803 | $84.3M | No change |
| MDT Medtronic PLC | 1.97% | 957,329 | $83.0M | Add +24.9% |
| ALNY Alnylam Pharmaceuticals Inc. | 1.85% | 234,543 | $77.6M | Reduce -47.4% |
| RLAY Relay Therapeutics Inc. | 1.85% | 7,795,242 | $77.6M | Reduce -6.6% |
| SYK Stryker Corp. | 1.70% | 217,237 | $71.4M | Reduce -39.8% |
| PCVX Vaxcyte Inc. | 1.65% | 1,190,697 | $69.2M | New |
| VERA Vera Therapeutics Inc. | 1.64% | 1,710,771 | $68.8M | Add +0.7% |
| EW Edwards Lifesciences Corp. | 1.60% | 839,451 | $67.2M | Reduce -19.5% |
| DMRA Damora Therapeutics Inc. | 1.42% | 2,298,000 | $59.5M | New |
| TNGX Tango Therapeutics Inc. | 1.19% | 2,400,000 | $50.2M | Reduce -38.9% |
| IDXX Idexx Laboratories Inc. | 1.19% | 89,131 | $50.1M | Reduce -5.7% |
| RARE Ultragenyx Pharmaceutical Inc. | 1.19% | 2,380,000 | $49.9M | Add +92148.1% |
| DXCM Dexcom Inc. | 1.18% | 788,766 | $49.5M | Reduce -6.9% |
| JBIO Jade Biosciences Inc. | 1.17% | 3,501,502 | $49.2M | Add +4.8% |
| EWTX Edgewise Therapeutics Inc. | 1.15% | 1,528,518 | $48.1M | No change |
| UNH Unitedhealth Group Inc. | 0.95% | 148,203 | $40.1M | Reduce -15.4% |
| DHR Danaher Corp. | 0.91% | 202,164 | $38.3M | Add +3.9% |
| CLDX Celldex Therapeutics Inc. | 0.91% | 1,200,000 | $38.1M | Reduce -66.8% |
| RMD Resmed Inc. | 0.85% | 159,346 | $35.8M | Reduce -1.2% |
| PODD Insulet Corp. | 0.82% | 163,656 | $34.3M | Reduce -12.3% |
| TMO Thermo Fisher Scientific Inc. | 0.75% | 64,412 | $31.7M | Reduce -1.0% |
| LLY Eli Lilly & Co. | 0.74% | 33,932 | $31.2M | Reduce -0.2% |
| GEHC GE Healthcare Technology | 0.71% | 416,887 | $29.7M | Reduce -1.8% |
| IRON Disc Medicine Inc. | 0.70% | 459,314 | $29.4M | New |
| JNJ Johnson & Johnson | 0.69% | 119,102 | $29.1M | Reduce -6.1% |
| ANNX Annexon Inc. | 0.68% | 5,157,290 | $28.6M | No change |
| CI The Cigna Group | 0.62% | 98,263 | $26.2M | Reduce -10.7% |
| ORKA Oruka Therapeutics Inc. | 0.59% | 507,008 | $24.9M | New |
| MRK Merck & Co. Inc. | 0.59% | 206,591 | $24.9M | Add +124.3% |
| ALGN Align Technology Inc. | 0.57% | 139,680 | $23.9M | Reduce -1.3% |
| STE Steris PLC | 0.53% | 99,878 | $22.1M | Reduce -1.8% |
| GMED Globus Medical Inc. Class A | 0.51% | 247,261 | $21.3M | Reduce -5.9% |
| GLUE Monte Rosa Therapeutics Inc. | 0.49% | 1,250,000 | $20.6M | New |
| ABBV Abbvie Inc. | 0.48% | 93,567 | $20.3M | Reduce -30.6% |
| COO The Cooper Cos Inc. | 0.46% | 272,184 | $19.5M | Reduce -6.8% |
| MCK McKesson Corp. | 0.46% | 22,352 | $19.3M | Reduce -10.9% |
| BDX Becton Dickinson and Co. | 0.46% | 121,887 | $19.2M | Reduce -54.1% |
| HCA HCA Healthcare Inc. | 0.43% | 37,765 | $17.9M | Reduce -14.0% |
| GKOS Glaukos Corp. | 0.37% | 145,703 | $15.7M | Reduce -44.4% |
| ELV Elevance Health Inc. | 0.37% | 52,518 | $15.4M | Reduce -24.6% |
| ZBH Zimmer Biomet Holdings Inc. | 0.33% | 155,571 | $14.1M | Reduce -34.8% |
| PRCT Procept Biorobotics Corp. | 0.30% | 502,286 | $12.6M | Reduce -2.5% |
| LIVN Livanova PLC | 0.28% | 186,185 | $11.8M | New |
| HUM Humana Inc. | 0.27% | 64,498 | $11.2M | Reduce -11.7% |
| TMDX Transmedics Group Inc. | 0.24% | 101,139 | $10.1M | Add +3.3% |
| VEEV Veeva Systems Inc. Class A | 0.24% | 56,517 | $9.9M | Reduce -29.8% |
| CNC Centene Corp. | 0.20% | 261,066 | $8.5M | Reduce -4.6% |
| TEVA Teva Pharmaceutical-SP ADR | 0.18% | 250,082 | $7.5M | Reduce -23.7% |
| THC Tenet Healthcare Corp. | 0.17% | 38,269 | $7.2M | Reduce -4.9% |
| TXG 10X Genomics Inc. Class A | 0.17% | 329,492 | $7.0M | Add +2.3% |
| CVS CVS Health Corp. | 0.15% | 89,363 | $6.4M | Reduce -18.1% |
| NTRA Natera Inc. | 0.15% | 31,694 | $6.3M | Reduce -43.4% |
| WAY Waystar Holding Corp. | 0.15% | 256,139 | $6.2M | Add +6.0% |
| MDLN Medline Inc. Class A | 0.14% | 136,635 | $6.1M | Add +16.1% |
| INSP Inspire Medical Systems Inc. | 0.12% | 99,735 | $5.1M | Reduce -1.0% |
| PRVA Privia Health Group Inc. | 0.11% | 226,703 | $4.7M | Reduce -49.4% |
| PEN Penumbra Inc. | 0.10% | 12,267 | $4.0M | Reduce -90.9% |
| RNA Atrium Therapeutics Inc. | 0.08% | 263,096 | $3.5M | New |
| PFE Pfizer Inc. | 0.07% | 107,635 | $3.0M | Add +89.3% |
| ILMN Illumina Inc. | 0.06% | 20,223 | $2.5M | Reduce -11.8% |
| KMTS Kestra Medical Technologies | 0.05% | 115,590 | $2.3M | Reduce -0.1% |
| OMDA Omada Health Inc. | 0.05% | 157,938 | $2.0M | Reduce -11.2% |
| BBIO Bridgebio Pharma Inc. | 0.04% | 25,377 | $1.9M | Add +5.3% |
| BNTX Biontech SE-ADR | 0.04% | 20,851 | $1.9M | Reduce -52.4% |
| RPRX Royalty Pharma PLC Class A | 0.04% | 38,296 | $1.8M | Add +190.1% |
| SPY SS SPDR S&P 500 ETF Trust-US | 0.04% | 2,700 | $1.8M | Reduce -12.9% |
| INSM Insmed Inc. | 0.04% | 10,034 | $1.6M | Reduce -27.9% |
| MDGL Madrigal Pharmaceuticals Inc. | 0.04% | 3,040 | $1.6M | Add +5.4% |
| MASI Masimo Corp. | 0.04% | 8,753 | $1.6M | Reduce -91.0% |
| PTGX Protagonist Therapeutics Inc. | 0.04% | 14,447 | $1.5M | Reduce -12.7% |
| UTHR United Therapeutics Corp. | 0.03% | 2,077 | $1.2M | Reduce -46.7% |
| ONC Beone Medicines Ltd.-ADR | 0.03% | 3,812 | $1.1M | Add +101.7% |
| PHR Phreesia Inc. | 0.03% | 130,992 | $1.1M | Reduce -28.5% |
| ADPT Adaptive Biotechnologies | 0.03% | 76,181 | $1.1M | Reduce -74.4% |
| BMY Bristol-Myers Squibb Co. | 0.02% | 17,038 | $1.0M | Reduce -74.6% |
| EHC Encompass Health Corp. | 0.02% | 9,829 | $951K | Reduce -48.5% |
| NAMS Newamsterdam Pharma Co. NV | 0.02% | 27,661 | $885K | Reduce -23.9% |
| AAPL Apple Inc. | 0.02% | 3,320 | $843K | No change |
| BLLN Billiontoone Inc. Class A | 0.02% | 10,554 | $833K | Reduce -0.3% |
| MLYS Mineralys Therapeutics Inc. | 0.02% | 29,374 | $796K | Add +48.2% |
| EQNR Equinor ASA-Spon ADR | 0.02% | 17,573 | $742K | New |
| XOM Exxon Mobil Corp. | 0.02% | 4,370 | $741K | New |
| BP BP PLC-Spons ADR | 0.02% | 15,644 | $735K | New |
| SHEL Shell PLC-ADR | 0.02% | 7,844 | $729K | New |
| BBNX Beta Bionics Inc. | 0.02% | 72,152 | $723K | Reduce -0.2% |
| BIIB Biogen Inc. | 0.02% | 3,653 | $670K | Add +2.5% |
| LEGN Legend Biotech Corp.-ADR | 0.02% | 35,886 | $649K | Reduce -43.9% |
| CSCO Cisco Systems Inc. | 0.01% | 8,000 | $621K | No change |
| NBIX Neurocrine Biosciences Inc. | 0.01% | 4,646 | $612K | Reduce -99.7% |
| BABA Alibaba Group Holding-SP ADR | 0.01% | 4,700 | $590K | No change |
| CYTK Cytokinetics Inc. | 0.01% | 8,841 | $583K | Reduce -4.2% |
| CERT Certara Inc. | 0.01% | 99,442 | $567K | No change |
| PRAX Praxis Precision Medicines I | 0.01% | 1,757 | $566K | New |
| PG The Procter & Gamble Co. | 0.01% | 3,900 | $563K | No change |
| MA Mastercard Inc. Class A | 0.01% | 1,100 | $550K | No change |
| COR Cencora Inc. | 0.01% | 1,716 | $539K | Add +229.4% |
| AXSM Axsome Therapeutics Inc. | 0.01% | 3,181 | $538K | Reduce -88.5% |
| GDX Vaneck Gold Miners ETF | 0.01% | 5,750 | $528K | Reduce -62.9% |
| AGMB Agomab Therapeutics NV | 0.01% | 50,000 | $525K | New |
| BLK BlackRock Inc. | 0.01% | 450 | $433K | No change |
| V Visa Inc. Class A | 0.01% | 1,400 | $423K | No change |
| CNTA Centessa Pharmaceuticals Ltd. | 0.01% | 9,030 | $359K | New |
| DNLI Denali Therapeutics Inc. | 0.01% | 17,766 | $341K | Add +148.9% |
| GPCR Structure Therapeutics Inc. | 0.01% | 6,803 | $328K | Reduce -95.3% |
| JD Jd.com Inc.-ADR | 0.01% | 11,000 | $325K | No change |
| ALKS Alkermes PLC | 0.01% | 8,870 | $314K | Add +34.5% |
| GRMN Garmin Ltd. | 0.01% | 1,321 | $306K | Reduce -23.5% |
| SMMT Summit Therapeutics Inc. | 0.01% | 15,858 | $301K | Add +11.2% |
| ACN Accenture PLC Class A | 0.01% | 1,500 | $297K | No change |
| ADBE Adobe Inc. | 0.01% | 1,200 | $292K | No change |
| AMZN Amazon.com Inc. | 0.01% | 1,353 | $282K | Reduce -61.8% |
| TVTX Travere Therapeutics Inc. | 0.01% | 8,899 | $264K | Add +132.5% |
| HALO Halozyme Therapeutics Inc. | 0.01% | 3,857 | $249K | New |
| OLMA Olema Pharmaceuticals Inc. | 0.01% | 16,443 | $245K | Add +321.4% |
| CRSP Crispr Therapeutics AG | 0.01% | 5,016 | $239K | Add +166.8% |
| TEM Tempus AI Inc. Class A | 0.01% | 4,950 | $224K | Add +3.6% |
| CAH Cardinal Health Inc. | 0.00% | 863 | $182K | Reduce -88.8% |
| PTCT PTC Therapeutics Inc. | 0.00% | 1,935 | $132K | Reduce -71.4% |
| IQV Iqvia Holdings Inc. | 0.00% | 740 | $126K | Reduce -98.2% |
| ASND Ascendis Pharma A/S | 0.00% | 536 | $123K | Reduce -97.8% |
| ABVX Abivax SA-ADR | 0.00% | 1,048 | $117K | New |
| CAI Caris Life Sciences Inc. | 0.00% | 6,418 | $115K | No change |
| ARWR Arrowhead Pharmaceuticals Inc. | 0.00% | 1,545 | $97K | Reduce -86.6% |
| GOOGL Alphabet Inc. Class A | 0.00% | 314 | $90K | Reduce -84.8% |
| RYTM Rhythm Pharmaceuticals Inc. | 0.00% | 1,016 | $88K | Reduce -86.5% |
| A Agilent Technologies Inc. | 0.00% | 664 | $76K | Add +89.7% |
| LH Labcorp Holdings Inc. | 0.00% | 280 | $75K | Reduce -95.1% |
| NVDA Nvidia Corp. | 0.00% | 408 | $71K | Reduce -89.6% |
| MSFT Microsoft Corp. | 0.00% | 172 | $64K | Reduce -86.6% |
| ZTS Zoetis Inc. | 0.00% | 533 | $63K | Reduce -26.9% |
| BBOT Bridgebio Oncology Therapeut | 0.00% | 6,982 | $62K | New |
| INCY Incyte Corp. | 0.00% | 486 | $46K | Reduce -89.8% |
| MTD Mettler-Toledo International | 0.00% | 36 | $45K | Reduce -5.3% |
| WVE Wave Life Sciences Ltd. | 0.00% | 5,261 | $38K | Reduce -99.7% |
| ORCL Oracle Corp. | 0.00% | 191 | $28K | Reduce -5.9% |
| DGX Quest Diagnostics Inc. | 0.00% | 131 | $26K | Reduce -98.2% |
| QCOM Qualcomm Inc. | 0.00% | 197 | $25K | Reduce -5.7% |
| RXRX Recursion Pharmaceuticals-A | 0.00% | 4,627 | $14K | Reduce -6.0% |
| QGEN Qiagen N.V. | 0.00% | 243 | $10K | New |