Rhythm PharmaceuticalsRYTM
13F holders, Q2 2026 (June 30)At the end of Q2 2026, 304 institutions reported holding Rhythm Pharmaceuticals Inc. (RYTM) in their 13F filings, up 19 from Q1 2026. 61 opened new positions and 41 sold out. The largest holders were Ra Capital Management, L.P. ($740.2M), BlackRock, Inc. ($683.6M) and Baker Bros. Advisors LP ($622.3M). 9 famous investors held it, including Stanley Druckenmiller (0.5% of Duquesne Family Office's portfolio), Ken Griffin (0.1% of Citadel Advisors's portfolio) and Steve Cohen (0.1% of Point72 Asset Management's portfolio).
- Company
- Rhythm Pharmaceuticals Inc.
- CUSIP
- 76243J105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 61 | $159.8M |
| Exits | 41 | $97.2M |
All 13F filers, Q1 2026 → Q2 2026: 8,513,201 shares bought and 5,547,792 shares sold, net +2,965,409 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 304 holders
| Ra Capital Management, L.P. | 6.44% | No change | 6,666,837 | $740.2M |
| BlackRock, Inc. | 0.01% | Reduce -1.3% | 6,156,902 | $683.6M |
| Baker Bros. Advisors LP | 3.13% | No change | 5,604,483 | $622.3M |
| Primecap Management Co. | 0.21% | Reduce -7.3% | 3,168,853 | $351.8M |
| Vanguard Portfolio Management LLC | 0.02% | Add +3.2% | 3,136,895 | $348.3M |
| Vanguard Capital Management LLC | 0.01% | Add +1.3% | 3,005,977 | $333.8M |
| JPMorgan Chase & Co. | 0.02% | Add +70.7% | 2,652,746 | $292.2M |
| Perceptive Advisors LLC | 4.47% | Add +8.9% | 2,586,295 | $287.2M |
| State Street Corp. | 0.01% | Add +13.3% | 2,573,529 | $285.7M |
| T. Rowe Price Associates Inc. | 0.03% | Add +55.1% | 2,566,171 | $284.9M |
| Westfield Capital Management Co. LP | 0.80% | Add +14.5% | 2,208,595 | $245.2M |
| Goldman Sachs Group Inc. | 0.02% | Add +8.2% | 2,126,502 | $236.1M |
| Federated Hermes, Inc. | 0.29% | Add +38.8% | 1,785,716 | $198.3M |
| Polar Capital Holdings Plc | 0.52% | Add +3.0% | 1,663,632 | $184.7M |
| Geode Capital Management, LLC | 0.01% | Add +8.3% | 1,533,698 | $170.3M |
| Capital Research Global Investors | 0.02% | Add +37.4% | 1,532,303 | $170.1M |
| Citadel Advisors | 0.08% | Reduce -10.9% | 1,263,652 | $140.3M |
| Checkpoint Capital L.P. | 33.79% | Reduce -3.4% | 1,186,000 | $131.7M |
| Siren, L.L.C. | 2.56% | Add +56.6% | 1,136,275 | $126.2M |
| Morgan Stanley | 0.01% | Add +58.0% | 1,112,240 | $123.5M |
| FMR LLC | 0.01% | Reduce -39.3% | 1,025,840 | $113.9M |
| Pictet Asset Management Holding SA | 0.10% | Add +43.6% | 957,785 | $106.3M |
| Jupiter Topco LLC | 0.04% | — | 925,490 | $102.8M |
| Woodline Partners LP | 0.26% | No change | 758,891 | $84.3M |
| Alliancebernstein L.P. | 0.03% | Reduce -1.7% | 894,723 | $77.8M |
| Clearbridge Investments, LLC | 0.06% | Add +14.3% | 696,473 | $77.3M |
| Rock Springs Capital Management LP | 3.75% | Add +0.4% | 692,598 | $76.9M |
| Norges Bank | 0.01% | — | 685,844 | $76.1M |
| Franklin Resources Inc. | 0.01% | Reduce -8.0% | 577,033 | $64.1M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +5.0% | 552,738 | $61.4M |
| Integral Health Asset Management, LLC | 2.51% | Reduce -8.3% | 550,000 | $61.1M |
| Invesco Ltd. | 0.00% | Add +49.1% | 543,271 | $60.3M |
| Northern Trust Corp. | 0.01% | Add +8.4% | 540,332 | $60.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Reduce -4.9% | 514,850 | $57.2M |
| Wellington Management Group LLP | 0.01% | Add +78.5% | 488,747 | $54.3M |
| Vanguard Fiduciary Trust Co. | 0.01% | Add +5.6% | 445,723 | $49.5M |
| Loomis Sayles & Co. L P | 0.06% | Reduce -6.7% | 434,102 | $48.2M |
| Candriam S.C.A. | 0.22% | Reduce -6.7% | 433,025 | $48.0M |
| Squarepoint Ops LLC | 0.09% | Add +60.8% | 422,921 | $47.0M |
| Point72 Asset Management | 0.07% | Reduce -51.1% | 414,210 | $46.0M |
| Sofinnova Investments, Inc. | 2.42% | Reduce -9.3% | 408,027 | $45.3M |
| Ameriprise Financial Inc. | 0.01% | Add +4.6% | 401,634 | $44.6M |
| Adage Capital Partners Gp, L.L.C. | 0.06% | Reduce -45.3% | 397,000 | $44.1M |
| Bank of New York Mellon Corp | 0.01% | Add +34.4% | 394,044 | $43.8M |
| Braidwell LP | 1.63% | Add +22.7% | 381,128 | $42.3M |
| Artisan Partners Limited Partnership | 0.06% | Reduce -9.2% | 354,816 | $39.4M |
| Bank of America Corp. | 0.00% | Reduce -48.2% | 325,470 | $36.1M |
| Orbimed Advisors LLC | 0.68% | Add +2.8% | 322,900 | $35.9M |
| Millennium Management | 0.02% | Reduce -29.9% | 316,719 | $35.2M |
| Silverarc Capital Management, LLC | 3.85% | Add +1.8% | 311,461 | $34.6M |
| Voya Investment Management LLC | 0.03% | Add +16.8% | 272,974 | $30.3M |
| Capital World Investors | 0.00% | Add +91.4% | 221,450 | $24.6M |
| Duquesne Family Office | 0.52% | New | 203,618 | $22.6M |
| Nuveen, LLC | 0.01% | Add +73.0% | 203,078 | $22.5M |
| BNP Paribas Financial Markets | 0.01% | Reduce -20.4% | 197,374 | $21.9M |
| Kennedy Capital Management LLC | 0.38% | Add +193.6% | 193,215 | $21.5M |
| Assenagon Asset Management S.A. | 0.03% | New | 186,491 | $20.7M |
| Schroder Investment Management Group | 0.01% | Add +21.9% | 160,518 | $17.7M |
| First Turn Management, LLC | 1.83% | New | 154,018 | $17.1M |
| New York State Common Retirement Fund | 0.02% | Add +18.3% | 148,152 | $16.4M |
| UBS Group AG | 0.00% | Reduce -37.7% | 144,378 | $16.0M |
| Nicholas Investment Partners, LP | 1.00% | New | 139,270 | $15.5M |
| ADAR1 Capital Management, LLC | 0.72% | Reduce -35.6% | 136,158 | $15.1M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.03% | Reduce -10.5% | 135,867 | $15.1M |
| Qube Research & Technologies Ltd | 0.02% | Reduce -51.6% | 134,410 | $14.9M |
| NEXTBio Capital Management LP | 6.73% | Add +4.5% | 131,758 | $14.6M |
| Driehaus Capital Management LLC | 0.08% | Reduce -70.4% | 129,285 | $14.4M |
| SummitTX Capital, L.P. | 0.37% | Reduce -23.7% | 126,401 | $14.0M |
| Logos Global Management LP | 0.60% | Reduce -72.2% | 125,000 | $13.9M |
| Opaleye Management Inc. | 1.23% | Reduce -0.4% | 122,500 | $13.6M |
| Segall Bryant & Hamill, LLC | 0.16% | New | 121,866 | $13.5M |
| Deutsche Bank AG | 0.00% | Reduce -18.6% | 115,232 | $12.8M |
| Longaeva Partners L.P. | 0.35% | New | 110,074 | $12.2M |
| Swiss National Bank | 0.01% | Reduce -2.2% | 109,700 | $12.2M |
| PFM Health Sciences, LP | 0.98% | Reduce -25.7% | 101,550 | $11.3M |
| Aberdeen Group plc | 0.01% | Add +19.6% | 94,946 | $10.5M |
| Axiom Investors LLC | 0.08% | Reduce -5.3% | 86,880 | $9.6M |
| Russell Investments Group, Ltd. | 0.01% | Reduce -25.1% | 86,709 | $9.6M |
| First Light Asset Management, LLC | 0.58% | Reduce -1.6% | 85,765 | $9.5M |
| Algert Global LLC | 0.11% | Add +42.6% | 83,431 | $9.3M |
| Granahan Investment Management, LLC | 0.33% | Add +7.2% | 83,270 | $9.2M |
| Neuberger Berman Group LLC | 0.01% | Add +13.1% | 83,035 | $9.2M |
| Sphera Funds Management LTD. | 1.28% | New | 80,400 | $8.9M |
| WCM Investment Management, LLC | 0.02% | Reduce -0.1% | 80,552 | $8.9M |
| Atom Investors LP | 0.73% | Add +28.9% | 73,465 | $8.2M |
| Silvercrest Asset Management Group LLC | 0.05% | Add +56.6% | 73,432 | $8.2M |
| Rhumbline Advisers | 0.01% | Add +5.0% | 73,333 | $8.1M |
| Wells Fargo & Company | 0.00% | Add +111.5% | 72,147 | $8.0M |
| Prudential Financial Inc. | 0.01% | Add +129.0% | 69,145 | $7.7M |
| Capital Fund Management S.A. | 0.05% | New | 68,548 | $7.6M |
| Renaissance Technologies | 0.01% | Reduce -73.5% | 68,281 | $7.6M |
| Picton Mahoney Asset Management | 0.07% | Add +30.8% | 65,880 | $7.3M |
| California State Teachers Retirement System | 0.01% | Reduce -2.7% | 64,031 | $7.1M |
| Blue Owl Capital Holdings LP | 1.04% | No change | 61,455 | $6.8M |
| ExodusPoint Capital Management, LP | 0.06% | Add +244.0% | 61,147 | $6.8M |
| AQR Capital Management | 0.00% | Reduce -0.1% | 59,208 | $6.6M |
| Citigroup Inc. | 0.00% | Add +373.0% | 58,347 | $6.5M |
| Raymond James Financial Inc. | 0.00% | Add +16.3% | 58,069 | $6.4M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +12.6% | 57,170 | $6.3M |
| Trexquant Investment LP | 0.04% | New | 56,248 | $6.2M |
"% of holder's portfolio" is RYTM's weight in each manager's 13F, not the share of Rhythm Pharmaceuticals Inc. the manager owns.