Camber Capital Management LP

In its 13F for Q2 2025 (holdings as of June 30, 2025, filed August 14, 2025), Camber Capital Management LP reported 23 stock positions worth $717.9 million. Its top holding was Zimmer Biomet (ZBH) at 12.7% of the portfolio, followed by Baxter International (BAX, 12.0%) and Humana (HUM, 10.2%). Compared with Q1 2025, it opened 4 new positions, sold out of 9, added to 1 and reduced 16. The biggest buy was a new position in Icon (ICLR) and the biggest sale an exit from PTC Therapeutics (PTCT).

Most Recent 13F
Q2 2025
Location
BOSTON, MA
CIK
0001444043
Portfolio Value
$717.9M (Q2 2025)
SEC Filing
0001654954-25-009644 ↗ filed Aug 14, 2025

Holdings Value

0$1.0B$2.0B$3.0B Q1 2024: $2.8B Q1 2024 Q2 2024: $2.6B Q2 2024 Q3 2024: $2.6B Q3 2024 Q4 2024: $2.5B Q4 2024 Q1 2025: $1.6B Q1 2025 Q2 2025: $717.9M $717.9M Q2 2025

Holdings 23 stocks · $717.9M

ZBH Zimmer Biomet Holdings Inc. 12.71% 1,000,000 $91.2M Reduce -55.6%
BAX Baxter International Inc. 12.02% 2,850,000 $86.3M Reduce -50.4%
HUM Humana Inc. 10.22% 300,000 $73.3M Reduce -58.6%
CVS CVS Health Corp. 10.09% 1,050,000 $72.4M Reduce -53.3%
GMED Globus Medical Inc. Class A 6.58% 800,000 $47.2M Reduce -36.0%
ICLR Icon PLC 6.08% 300,000 $43.6M New
ASND Ascendis Pharma A/S 6.01% 250,000 $43.1M Reduce -28.6%
MRK Merck & Co. Inc. 5.51% 500,000 $39.6M New
PFE Pfizer Inc. 5.06% 1,500,000 $36.4M Reduce -40.0%
BMRN Biomarin Pharmaceutical Inc. 4.59% 600,000 $33.0M Add +20.0%
UNH Unitedhealth Group Inc. 4.35% 100,000 $31.2M New
VTRS Viatris Inc. 3.42% 2,750,000 $24.6M Reduce -63.3%
BKD Brookdale Senior Living Inc. 2.08% 2,150,000 $15.0M Reduce -65.6%
ZIMV Zimvie Inc. 2.08% 1,600,000 $15.0M Reduce -15.1%
APLS Apellis Pharmaceuticals Inc. 2.05% 850,000 $14.7M New
MYGN Myriad Genetics Inc. 1.48% 2,000,000 $10.6M Reduce -14.9%
EVH Evolent Health Inc. Class A 1.33% 850,000 $9.6M Reduce -71.7%
CON Concentra Group Holdings Par 1.15% 400,000 $8.2M Reduce -75.0%
INGN Inogen Inc. 0.95% 975,000 $6.9M No change
DNLI Denali Therapeutics Inc. 0.78% 400,000 $5.6M Reduce -68.0%
TBPH Theravance Biopharma Inc. 0.69% 450,000 $5.0M Reduce -55.0%
ANAB Anaptysbio Inc. 0.39% 125,000 $2.8M Reduce -83.3%
OSUR Orasure Technologies Inc. 0.38% 900,000 $2.7M No change

Options reported separately and not counted above: SPY puts ($308.9M), GSK calls ($38.4M).

Portfolio Sells Q1 2025 → Q2 2025

PTCT PTC Therapeutics Inc. Sold out 0.00% −4.77
CI The Cigna Group Sold out 0.00% −4.11
QGEN Qiagen N.V. Sold out 0.00% −3.51
SRPT Sarepta Therapeutics Inc. Sold out 0.00% −3.19
ZBH Zimmer Biomet Holdings Inc. Reduce -55.6% 12.71% −3.18
HUM Humana Inc. Reduce -58.6% 10.22% −1.75
IONS Ionis Pharmaceuticals Inc. Sold out 0.00% −1.36
MLTX Moonlake Immunotherapeutics Sold out 0.00% −1.08
CON Concentra Group Holdings Par Reduce -75.0% 1.15% −1.02
VTRS Viatris Inc. Reduce -63.3% 3.42% −0.66
TXG 10X Genomics Inc. Class A Sold out 0.00% −0.54
ANAB Anaptysbio Inc. Reduce -83.3% 0.39% −0.48
EVH Evolent Health Inc. Class A Reduce -71.7% 1.33% −0.44
BKD Brookdale Senior Living Inc. Reduce -65.6% 2.08% −0.36
GPCR Structure Therapeutics Inc. Sold out 0.00% −0.32
DNLI Denali Therapeutics Inc. Reduce -68.0% 0.78% −0.28
BAX Baxter International Inc. Reduce -50.4% 12.02% −0.26
GMAB Genmab A/S -SP ADR Sold out 0.00% −0.06
TBPH Theravance Biopharma Inc. Reduce -55.0% 0.69% +0.13
MYGN Myriad Genetics Inc. Reduce -14.9% 1.48% +0.18
CVS CVS Health Corp. Reduce -53.3% 10.09% +0.58
ZIMV Zimvie Inc. Reduce -15.1% 2.08% +0.81
GMED Globus Medical Inc. Class A Reduce -36.0% 6.58% +0.87
PFE Pfizer Inc. Reduce -40.0% 5.06% +1.11
ASND Ascendis Pharma A/S Reduce -28.6% 6.01% +2.61

Portfolio Buys Q1 2025 → Q2 2025

ICLR Icon PLC New 6.08% +6.08
MRK Merck & Co. Inc. New 5.51% +5.51
UNH Unitedhealth Group Inc. New 4.35% +4.35
BMRN Biomarin Pharmaceutical Inc. Add +20.0% 4.59% +2.39
APLS Apellis Pharmaceuticals Inc. New 2.05% +2.05

Options Activity Q1 2025 → Q2 2025

SPY SS SPDR S&P 500 ETF Trust-US put Reduce -66.7% 500,000 $308.9M
PFE Pfizer Inc. call Sold out 6,800,000 $172.3Mbefore exit
XBI SS SPDR S&P Biotech ETF put Sold out 2,000,000 $162.2Mbefore exit

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2025 23$717.9MZBH, BAX, HUM, CVS, GMED
Q1 2025 28$1.6BZBH, BAX, HUM, CVS, GMED
Q4 2024 35$2.5BMDT, VTRS, ZBH, HUM, PTCT
Q3 2024 31$2.6BZBH, MDT, BAX, VTRS, GMED
Q2 2024 34$2.6BZBH, BAX, MDT, UHS, GMED
Q1 2024 33$2.8BZBH, UHS, BAX, THC, VTRS