Camber Capital Management LP In its 13F for Q4 2024 (holdings as of December 31, 2024, filed February 14, 2025), Camber Capital Management LP reported 35 stock positions worth $2.5 billion . Its top holding was Medtronic (MDT) at 8.7% of the portfolio, followed by Viatris (VTRS, 7.4% ) and Zimmer Biomet (ZBH, 6.7% ). Compared with Q3 2024, it opened 8 new positions, sold out of 4, added to 8 and reduced 6. The biggest buy was a new position in Pfizer (PFE) and the biggest sale Baxter International (BAX, shares −29% ).
Location BOSTON, MA
CIK 0001444043
Portfolio Value $2.5B (Q4 2024) Holdings 35 stocks · $2.5B Holdings quarter Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024 Q1 2024
Stock % Of Portfolio ▼ Shares Held Total Value Change vs Q3 2024 MDT Medtronic PLC 8.65% 2,750,000 $219.7M No change VTRS Viatris Inc. 7.35% 15,000,000 $186.8M No change ZBH Zimmer Biomet Holdings Inc. 6.68% 1,605,000 $169.5M Reduce -35.8% HUM Humana Inc. 6.49% 650,000 $164.9M Add +225.0% PTCT PTC Therapeutics Inc. 5.69% 3,200,000 $144.4M Reduce -8.6% JAZZ Jazz Pharmaceuticals PLC 5.58% 1,150,000 $141.6M No change BAX Baxter International Inc. 5.31% 4,625,000 $134.9M Reduce -28.9% CVS CVS Health Corp. 5.30% 3,000,000 $134.7M Add +100.0% PFE Pfizer Inc. 5.22% 5,000,000 $132.7M New SRPT Sarepta Therapeutics Inc. 4.79% 1,000,000 $121.6M Add +29.0% ASND Ascendis Pharma A/S 4.34% 800,000 $110.1M Add +14.3% GMED Globus Medical Inc. Class A 3.99% 1,225,000 $101.3M Reduce -43.0% GSK GSK PLC-Spon ADR 3.33% 2,500,000 $84.5M Reduce -16.7% BKD Brookdale Senior Living Inc. 2.76% 13,935,000 $70.1M No change CON Concentra Group Holdings Par 2.73% 3,500,000 $69.2M Add +77.2% QGEN Qiagen NV 2.63% 1,500,000 $66.8M No change DNLI Denali Therapeutics Inc. 1.81% 2,250,000 $45.9M Add +12.5% EVH Evolent Health Inc. Class A 1.77% 4,000,000 $45.0M Add +185.7% ALKS Alkermes PLC 1.70% 1,500,000 $43.1M Add +650.0% MYGN Myriad Genetics Inc. 1.67% 3,100,000 $42.5M Reduce -21.5% MEDP Medpace Holdings Inc. 1.64% 125,000 $41.5M No change CI The Cigna Group 1.63% 150,000 $41.4M New ZIMV Zimvie Inc. 1.50% 2,725,000 $38.0M No change BMRN Biomarin Pharmaceutical Inc. 1.16% 450,000 $29.6M New MLTX Moonlake Immunotherapeutics 0.94% 441,000 $23.9M No change IONS Ionis Pharmaceuticals Inc. 0.86% 625,000 $21.9M New HLF Herbalife Ltd. 0.79% 3,000,000 $20.1M No change INGN Inogen Inc. 0.72% 2,000,000 $18.3M No change ANAB Anaptysbio Inc. 0.65% 1,250,000 $16.6M New OSUR Orasure Technologies Inc. 0.60% 4,250,000 $15.3M No change TXG 10X Genomics Inc. Class A 0.57% 1,000,000 $14.4M New MRUS Merus NV 0.41% 250,000 $10.5M New TBPH Theravance Biopharma Inc. 0.37% 1,000,000 $9.4M No change GPCR Structure Therapeutics Inc. 0.32% 300,000 $8.1M New GMAB Genmab A/S -SP ADR 0.04% 50,000 $1.0M No change
Options reported separately and not counted above: SPY puts ($1.5B), GSK calls ($169.1M), PFE calls ($132.7M).
Other holdings (1): bonds, preferreds, convertibles and warrants · $17.2M (not counted above) Total filed on the 13F, all lines: $2.6B.
Portfolio Sells Q3 2024 → Q4 2024 Portfolio Sells quarter Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024 Q1 2024
Stock Change vs Q3 2024 % Of Portfolio Change To Portfolio ▲ BAX Baxter International Inc. Reduce -28.9% 5.31% −4.36 ZBH Zimmer Biomet Holdings Inc. Reduce -35.8% 6.68% −3.90 SEM Select Medical Holdings Corp. Sold out 0.00% −2.90 MYGN Myriad Genetics Inc. Reduce -21.5% 1.67% −2.57 GMED Globus Medical Inc. Class A Reduce -43.0% 3.99% −2.04 GSK GSK PLC-Spon ADR Reduce -16.7% 3.33% −1.48 UHS Universal Health Services-B Sold out 0.00% −1.12 BCYC Bicycle Therapeutics PLC-ADR Sold out 0.00% −0.81 SKIN Skinhealth Systems Inc. Sold out 0.00% −0.08 PTCT PTC Therapeutics Inc. Reduce -8.6% 5.69% +0.60
Portfolio Buys Q3 2024 → Q4 2024 Portfolio Buys quarter Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024 Q1 2024
Stock Change vs Q3 2024 % Of Portfolio Change To Portfolio ▼ PFE Pfizer Inc. New 5.22% +5.22 HUM Humana Inc. Add +225.0% 6.49% +4.01 CI The Cigna Group New 1.63% +1.63 CVS CVS Health Corp. Add +100.0% 5.30% +1.61 ALKS Alkermes PLC Add +650.0% 1.70% +1.48 BMRN Biomarin Pharmaceutical Inc. New 1.16% +1.16 CON Concentra Group Holdings Par Add +77.2% 2.73% +1.00 SRPT Sarepta Therapeutics Inc. Add +29.0% 4.79% +1.00 IONS Ionis Pharmaceuticals Inc. New 0.86% +0.86 ANAB Anaptysbio Inc. New 0.65% +0.65 TXG 10X Genomics Inc. Class A New 0.57% +0.57 MRUS Merus NV New 0.41% +0.41 GPCR Structure Therapeutics Inc. New 0.32% +0.32 ASND Ascendis Pharma A/S Add +14.3% 4.34% +0.24 EVH Evolent Health Inc. Class A Add +185.7% 1.77% +0.22 DNLI Denali Therapeutics Inc. Add +12.5% 1.81% −0.48
Options Activity Q3 2024 → Q4 2024 Security Type Change vs Q3 2024 Underlying Shares Value ▼ SPY SS SPDR S&P 500 ETF Trust-US put Add +150.0% 2,500,000 $1.5B GSK GSK PLC-Spon ADR call New 5,000,000 $169.1M PFE Pfizer Inc. call New 5,000,000 $132.7M
Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.
All Filings Quarter Positions 13F Reported Value Top Holdings Q2 2025 23 $717.9M ZBH, BAX, HUM, CVS, GMED Q1 2025 28 $1.6B ZBH, BAX, HUM, CVS, GMED Q4 2024 35 $2.5B MDT, VTRS, ZBH, HUM, PTCT Q3 2024 31 $2.6B ZBH, MDT, BAX, VTRS, GMED Q2 2024 34 $2.6B ZBH, BAX, MDT, UHS, GMED Q1 2024 33 $2.8B ZBH, UHS, BAX, THC, VTRS