Column Group LLC
In its 13F for Q3 2025 (holdings as of September 30, 2025, filed November 14, 2025), Column Group LLC reported 5 stock positions worth $81.0 million. Its top holding was Oric Pharmaceuticals (ORIC) at 52.5% of the portfolio, followed by Surrozen (SRZN, 23.9%) and Tenaya Therapeutics (TNYA, 18.3%). Compared with Q2 2025, it reduced 1. The biggest sale was Rapt Therapeutics (shares −88%).
- Most Recent 13F
- Q2 2026
- Location
- San Francisco, CA
- CIK
- 0001833486
- Portfolio Value
- $81.0M (Q3 2025)
- SEC Filing
- 0001193125-25-282923 ↗ filed Nov 14, 2025
Holdings Value
Holdings 5 stocks · $81.0M
| ORIC Oric Pharmaceuticals Inc. | 52.48% | 3,540,777 | $42.5M | No change |
| SRZN Surrozen Inc. | 23.88% | 1,499,773 | $19.3M | No change |
| TNYA Tenaya Therapeutics Inc. | 18.35% | 9,400,290 | $14.9M | No change |
| RAPT THERAPEUTICS INC | 5.29% | 166,075 | $4.3M | Reduce -87.5% |
| RVMD Revolution Medicines Inc. | 0.00% | 46 | $2K | No change |
Portfolio Sells Q2 2025 → Q3 2025
| RAPT THERAPEUTICS INC | Reduce -87.5% | 5.29% | −10.88 |
Portfolio Buys Q2 2025 → Q3 2025
| None this quarter. | |||
All Filings
| Quarter | Positions | 13F Reported Value | Top Holdings |
|---|---|---|---|
| Q2 2026 | 3 | $88.1M | SRZN, ORIC, RVMD |
| Q1 2026 | 3 | $100.7M | SRZN, ORIC, RVMD |
| Q4 2025 | 5 | $82.8M | SRZN, ORIC, TNYA, RAPT THERAPEUTICS INC, RVMD |
| Q3 2025 | 5 | $81.0M | ORIC, SRZN, TNYA, RAPT THERAPEUTICS INC, RVMD |
| Q2 2025 | 5 | $65.7M | ORIC, SRZN, RAPT THERAPEUTICS INC, TNYA, RVMD |
| Q1 2025 | 5 | $44.2M | ORIC, SRZN, TNYA, RAPT THERAPEUTICS INC, RVMD |
| Q4 2024 | 5 | $55.7M | ORIC, TNYA, SRZN, RAPT THERAPEUTICS INC, RVMD |
| Q3 2024 | 6 | $69.6M | ORIC, TNYA, SRZN, RAPT THERAPEUTICS INC, SGMT |
| Q2 2024 | 6 | $71.3M | TNYA, ORIC, SRZN, RAPT THERAPEUTICS INC, SGMT |
| Q1 2024 | 7 | $160.5M | TNYA, ORIC, NGM, RAPT THERAPEUTICS INC, SRZN |