Column Group LLC

In its 13F for Q1 2026 (holdings as of March 31, 2026, filed May 18, 2026), Column Group LLC reported 3 stock positions worth $100.7 million. Its top holding was Surrozen (SRZN) at 55.4% of the portfolio, followed by Oric Pharmaceuticals (ORIC, 44.5%) and Revolution Medicines (RVMD, 0.0%). Compared with Q4 2025, it sold out of 2 and added to 1. The biggest buy was Surrozen (SRZN, shares +4%) and the biggest sale an exit from Tenaya Therapeutics (TNYA).

Most Recent 13F
Q2 2026
Location
San Francisco, CA
CIK
0001833486
Portfolio Value
$100.7M (Q1 2026)
SEC Filing
0001193125-26-227853 ↗ filed May 18, 2026

Holdings Value

0$50.0M$100.0M$150.0M$200.0M Q1 2024: $160.5M Q1 2024 Q2 2024: $71.3M Q2 2024 Q3 2024: $69.6M Q3 2024 Q4 2024: $55.7M Q4 2024 Q1 2025: $44.2M Q1 2025 Q2 2025: $65.7M Q2 2025 Q3 2025: $81.0M Q3 2025 Q4 2025: $82.8M Q4 2025 Q1 2026: $100.7M $100.7M Q1 2026 Q2 2026: $88.1M Q2 2026

Holdings 3 stocks · $100.7M
SRZN Surrozen Inc. 55.45% 1,916,950 $55.8M Add +3.5%
ORIC Oric Pharmaceuticals Inc. 44.55% 3,540,777 $44.9M No change
RVMD Revolution Medicines Inc. 0.00% 46 $4K No change

Portfolio Sells Q4 2025 → Q1 2026
TNYA Tenaya Therapeutics Inc. Sold out 0.00% −8.08
RAPT THERAPEUTICS INC Sold out 0.00% −6.39

Portfolio Buys Q4 2025 → Q1 2026
SRZN Surrozen Inc. Add +3.5% 55.45% +4.91

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 3$88.1MSRZN, ORIC, RVMD
Q1 2026 3$100.7MSRZN, ORIC, RVMD
Q4 2025 5$82.8MSRZN, ORIC, TNYA, RAPT THERAPEUTICS INC, RVMD
Q3 2025 5$81.0MORIC, SRZN, TNYA, RAPT THERAPEUTICS INC, RVMD
Q2 2025 5$65.7MORIC, SRZN, RAPT THERAPEUTICS INC, TNYA, RVMD
Q1 2025 5$44.2MORIC, SRZN, TNYA, RAPT THERAPEUTICS INC, RVMD
Q4 2024 5$55.7MORIC, TNYA, SRZN, RAPT THERAPEUTICS INC, RVMD
Q3 2024 6$69.6MORIC, TNYA, SRZN, RAPT THERAPEUTICS INC, SGMT
Q2 2024 6$71.3MTNYA, ORIC, SRZN, RAPT THERAPEUTICS INC, SGMT
Q1 2024 7$160.5MTNYA, ORIC, NGM, RAPT THERAPEUTICS INC, SRZN