Cormorant Asset Management, LP

In its 13F for Q2 2025 (holdings as of June 30, 2025, filed August 14, 2025), Cormorant Asset Management, LP reported 42 stock positions worth $1.3 billion. Its top holding was Moonlake Immunotherapeutics (MLTX) at 29.9% of the portfolio, followed by Eyepoint (EYPT, 5.8%) and Bridgebio Pharma (BBIO, 5.1%). Compared with Q1 2025, it opened 3 new positions, sold out of 3, added to 4 and reduced 16. The biggest buy was a new position in Verona Pharma (VRNA) and the biggest sale Janux Therapeutics (JANX, shares −25%).

Most Recent 13F
Q2 2026
Location
BOSTON, MA
CIK
0001583977
Portfolio Value
$1.3B (Q2 2025)
SEC Filing
0001583977-25-000007 ↗ filed Aug 14, 2025

Holdings Value

0$500.0M$1.0B$1.5B$2.0B$2.5B Q1 2024: $2.3B Q1 2024 Q2 2024: $1.7B Q2 2024 Q3 2024: $1.9B Q3 2024 Q4 2024: $1.8B Q4 2024 Q1 2025: $1.3B Q1 2025 Q2 2025: $1.3B $1.3B Q2 2025 Q3 2025: $1.4B Q3 2025 Q4 2025: $1.8B Q4 2025 Q1 2026: $2.0B Q1 2026 Q2 2026: $2.0B Q2 2026

Holdings 42 stocks · $1.3B

MLTX Moonlake Immunotherapeutics 29.86% 8,494,151 $400.9M No change
EYPT Eyepoint Inc. 5.84% 8,325,000 $78.3M No change
BBIO Bridgebio Pharma Inc. 5.15% 1,600,000 $69.1M Reduce -20.0%
PRAX Praxis Precision Medicines I 5.09% 1,625,000 $68.3M Reduce -6.9%
MRUS Merus NV 4.39% 1,120,000 $58.9M Add +51.4%
EWTX Edgewise Therapeutics Inc. 4.15% 4,251,992 $55.7M Add +3.7%
INSM Insmed Inc. 4.05% 540,000 $54.3M Add +2.9%
ACLX Arcellx Inc. 3.92% 800,000 $52.7M Reduce -23.8%
NAMS Newamsterdam Pharma Co. NV 2.93% 2,175,000 $39.4M Reduce -23.0%
JANX Janux Therapeutics Inc. 2.58% 1,500,000 $34.6M Reduce -25.0%
RAPP Rapport Therapeutics Inc. 2.49% 2,940,921 $33.4M No change
VRNA Verona Pharma Ltd. 2.47% 350,000 $33.1M New
BBOT Bridgebio Oncology Therapeut filed as HELIX ACQUISITION CORP II 2.30% 2,909,000 $30.9M No change
DRUG Bright Minds Biosciences Inc. 2.06% 1,059,331 $27.7M No change
CNTA Centessa Pharmaceuticals Ltd. 2.04% 2,086,600 $27.4M Reduce -7.7%
PHVS Pharvaris NV 1.91% 1,454,660 $25.6M Reduce -0.8%
GHRS GH Research PLC 1.82% 2,009,482 $24.5M No change
SPRY Ars Pharmaceuticals Inc. 1.43% 1,100,000 $19.2M Reduce -31.3%
CRBP Corbus Pharmaceuticals Holdi 1.22% 2,375,000 $16.4M No change
ABVX Abivax SA-ADR 1.21% 2,130,000 $16.3M No change
CGON CG Oncology Inc. 1.21% 625,000 $16.3M Reduce -19.4%
ARQT Arcutis Biotherapeutics Inc. 1.04% 1,000,000 $14.0M Reduce -25.9%
CRGX Cargo Therapeutics Inc. 1.04% 3,381,277 $13.9M No change
TARS Tarsus Pharmaceuticals Inc. 0.91% 300,000 $12.2M Reduce -25.0%
CRNX Crinetics Pharmaceuticals Inc. 0.86% 400,000 $11.5M Reduce -33.3%
MTSR Metsera Inc. 0.85% 400,000 $11.4M No change
AARD Aardvark Therapeutics Inc. 0.81% 800,189 $10.8M No change
AXSM Axsome Therapeutics Inc. 0.78% 100,000 $10.4M Reduce -60.0%
BIOA Bioage Labs Inc. 0.66% 2,140,605 $8.8M Reduce -18.6%
ENGN Engene Holdings Inc. 0.63% 2,323,595 $8.5M No change
MBX MBX Biosciences Inc. 0.59% 700,000 $8.0M No change
CABA Cabaletta Bio Inc. 0.57% 5,000,000 $7.6M New
ALMS Alumis Inc. 0.48% 2,147,396 $6.4M No change
BMEA Biomea Fusion Inc. 0.48% 3,570,872 $6.4M No change
KRRO Korro Bio Inc. 0.43% 465,000 $5.8M Add +22.3%
PCVX Vaxcyte Inc. 0.42% 175,000 $5.7M No change
RNAM Avidity Biosciences Inc. 0.42% 200,000 $5.7M Reduce -50.0%
ELVN Enliven Therapeutics Inc. 0.30% 200,000 $4.0M Reduce -20.0%
STOK Stoke Therapeutics Inc. 0.21% 254,161 $2.9M No change
KALA Kala Bio Inc. 0.21% 603,027 $2.9M No change
VYNE THERAPEUTICS INC 0.17% 1,370,938 $2.3M New
BHVN Biohaven Ltd. 0.01% 10,000 $141K No change

Portfolio Sells Q1 2025 → Q2 2025

JANX Janux Therapeutics Inc. Reduce -25.0% 2.58% −1.51
NAMS Newamsterdam Pharma Co. NV Reduce -23.0% 2.93% −1.44
AXSM Axsome Therapeutics Inc. Reduce -60.0% 0.78% −1.43
ACLX Arcellx Inc. Reduce -23.8% 3.92% −1.29
CRNX Crinetics Pharmaceuticals Inc. Reduce -33.3% 0.86% −0.67
TARS Tarsus Pharmaceuticals Inc. Reduce -25.0% 0.91% −0.65
RYTM Rhythm Pharmaceuticals Inc. Sold out 0.00% −0.60
OKUR Onkure Therapeutics Inc. Class A Sold out 0.00% −0.60
ARQT Arcutis Biotherapeutics Inc. Reduce -25.9% 1.04% −0.55
RNAM Avidity Biosciences Inc. Reduce -50.0% 0.42% −0.47
CNTA Centessa Pharmaceuticals Ltd. Reduce -7.7% 2.04% −0.42
PLRX Pliant Therapeutics Inc. Sold out 0.00% −0.31
CGON CG Oncology Inc. Reduce -19.4% 1.21% −0.23
SPRY Ars Pharmaceuticals Inc. Reduce -31.3% 1.43% −0.09
BIOA Bioage Labs Inc. Reduce -18.6% 0.66% −0.09
BBIO Bridgebio Pharma Inc. Reduce -20.0% 5.15% −0.09
ELVN Enliven Therapeutics Inc. Reduce -20.0% 0.30% −0.07
PRAX Praxis Precision Medicines I Reduce -6.9% 5.09% +0.09
PHVS Pharvaris NV Reduce -0.8% 1.91% +0.16

Portfolio Buys Q1 2025 → Q2 2025

VRNA Verona Pharma Ltd. New 2.47% +2.47
MRUS Merus NV Add +51.4% 4.39% +2.03
INSM Insmed Inc. Add +2.9% 4.05% +1.02
CABA Cabaletta Bio Inc. New 0.57% +0.57
VYNE THERAPEUTICS INC New 0.17% +0.17
KRRO Korro Bio Inc. Add +22.3% 0.43% −0.07
EWTX Edgewise Therapeutics Inc. Add +3.7% 4.15% −2.68

Options Activity Q1 2025 → Q2 2025

NAMS Newamsterdam Pharma Co. NV call Sold out 250,000 $5.1Mbefore exit
JANX Janux Therapeutics Inc. call Sold out 150,000 $4.0Mbefore exit

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 50$2.0BPRAX, BBOT, PBLS, RAPP, ERAS
Q1 2026 46$2.0BPRAX, BBOT, EYPT, EWTX, ERAS
Q4 2025 32$1.8BPRAX, BBOT, ABVX, EYPT, RAPP
Q3 2025 36$1.4BBBOT, ABVX, EYPT, RAPP, BBIO
Q2 2025 42$1.3BMLTX, EYPT, BBIO, PRAX, MRUS
Q1 2025 42$1.3BMLTX, EWTX, BBIO, ACLX, PRAX
Q4 2024 48$1.8BMLTX, PRAX, JANX, ACLX, EWTX
Q3 2024 45$1.9BMLTX, PCVX, ACLX, LBPH, EWTX
Q2 2024 47$1.7BMLTX, CRBP, ACLX, PCVX, LBPH
Q1 2024 56$2.3BMLTX, EYPT, ACLX, ALPN, BBIO