MBX BiosciencesMBX
13F holders, Q2 2026 (June 30)172holders +15
35new positions
21sold out
3famous investors
$55.18avg. 13F price*
At the end of Q2 2026, 172 institutions reported holding MBX Biosciences Inc. (MBX) in their 13F filings, up 15 from Q1 2026. 35 opened new positions and 21 sold out. The largest holders were Frazier Life Sciences Management, L.P. ($367.2M), FMR LLC ($293.8M) and Wellington Management Group LLP ($274.8M). 3 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- MBX Biosciences Inc.
- CUSIP
- 55287L101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 35 | $176.3M |
| Exits | 21 | $53.8M |
All 13F filers, Q1 2026 → Q2 2026: 9,919,290 shares bought and 6,989,099 shares sold, net +2,930,191 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 172 holders
| Frazier Life Sciences Management, L.P. | 8.01% | No change | 6,652,013 | $367.2M |
| FMR LLC | 0.01% | Add +81.3% | 5,322,885 | $293.8M |
| Wellington Management Group LLP | 0.05% | Add +56.0% | 4,977,523 | $274.8M |
| NEA Management Company, LLC | 12.56% | No change | 3,614,486 | $199.5M |
| Orbimed Advisors LLC | 3.59% | Reduce -5.8% | 3,428,736 | $189.3M |
| BlackRock, Inc. | 0.00% | Add +13.0% | 3,323,672 | $183.5M |
| Paradigm Biocapital Advisors LP | 2.59% | New | 2,508,015 | $138.4M |
| NVP Associates, LLC | 35.93% | No change | 2,136,335 | $117.9M |
| Deep Track Capital, LP | 1.41% | Reduce -37.2% | 1,732,569 | $95.6M |
| Polar Capital Holdings Plc | 0.25% | Reduce -0.8% | 1,608,514 | $88.8M |
| Vanguard Capital Management LLC | 0.00% | Reduce -0.0% | 1,477,388 | $81.6M |
| Aaron Wealth Advisors LLC | 3.27% | Reduce -0.0% | 1,167,799 | $64.5M |
| Driehaus Capital Management LLC | 0.34% | Add +3.8% | 1,056,579 | $58.3M |
| Kynam Capital Management, LP | 2.85% | No change | 934,799 | $51.6M |
| Woodline Partners LP | 0.15% | Add +0.0% | 900,092 | $49.7M |
| Eventide Asset Management, LLC | 0.64% | Reduce -1.9% | 873,492 | $48.2M |
| State Street Corp. | 0.00% | Add +9.8% | 864,466 | $47.7M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -20.8% | 814,807 | $45.0M |
| Parkman Healthcare Partners LLC | 4.54% | Add +0.0% | 800,173 | $44.2M |
| Geode Capital Management, LLC | 0.00% | Add +15.3% | 773,072 | $42.7M |
| Braidwell LP | 1.51% | Reduce -52.4% | 710,880 | $39.2M |
| TCG Crossover Management, LLC | 0.86% | No change | 650,000 | $35.9M |
| Cormorant Asset Management, LP | 1.56% | Reduce -50.9% | 550,000 | $30.4M |
| Soleus Capital Management, L.P. | 0.98% | Add +188.0% | 515,279 | $28.4M |
| Goldman Sachs Group Inc. | 0.00% | Add +0.2% | 459,005 | $25.3M |
| Marshall Wace, LLP | 0.02% | Add +540.9% | 401,885 | $22.2M |
| EcoR1 Capital, LLC | 1.06% | Reduce -50.0% | 388,500 | $21.4M |
| Vanguard Portfolio Management LLC | 0.00% | Add +18.2% | 346,717 | $19.1M |
| Bank of America Corp. | 0.00% | Add +939.8% | 298,927 | $16.5M |
| Rock Springs Capital Management LP | 0.80% | Add +3.6% | 298,218 | $16.5M |
| Candriam S.C.A. | 0.07% | Reduce -1.5% | 289,893 | $16.0M |
| UBS Group AG | 0.00% | Reduce -21.4% | 272,747 | $15.1M |
| Opaleye Management Inc. | 1.30% | No change | 260,000 | $14.4M |
| Franklin Resources Inc. | 0.00% | New | 252,665 | $13.9M |
| Schonfeld Strategic Advisors LLC | 0.07% | Add +100.8% | 248,670 | $13.7M |
| Morgan Stanley | 0.00% | Add +687.5% | 248,558 | $13.7M |
| Northern Trust Corp. | 0.00% | Add +17.1% | 246,678 | $13.6M |
| Dimensional Fund Advisors LP | 0.00% | Add +399.9% | 233,700 | $12.9M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +8.5% | 233,095 | $12.9M |
| Millennium Management | 0.01% | Reduce -59.9% | 226,151 | $12.5M |
| Tetragon Partners GP Ltd | 1.83% | Add +39.9% | 203,543 | $11.2M |
| Vanguard Fiduciary Trust Co. | 0.00% | Add +18.4% | 201,429 | $11.1M |
| Caligan Partners LP | 0.53% | Reduce -76.4% | 200,000 | $11.0M |
| D. E. Shaw & Co. | 0.01% | Reduce -36.7% | 182,767 | $10.1M |
| JPMorgan Chase & Co. | 0.00% | Reduce -5.1% | 139,611 | $7.5M |
| KVP Capital Advisors, LP | 4.92% | No change | 121,524 | $6.7M |
| Two Sigma Investments, LP | 0.00% | Reduce -1.4% | 113,475 | $6.3M |
| Burkehill Global Management, LP | 0.21% | No change | 100,000 | $5.5M |
| Nuveen, LLC | 0.00% | Add +20.7% | 98,733 | $5.5M |
| TD Asset Management Inc | 0.00% | Reduce -17.6% | 95,598 | $5.3M |
| Elmind Capital, LP | 1.26% | Reduce -56.9% | 91,000 | $5.0M |
| Bank of New York Mellon Corp | 0.00% | Add +10.8% | 88,927 | $4.9M |
| Prudential Financial Inc. | 0.01% | New | 88,045 | $4.9M |
| Barclays PLC | 0.00% | Add +642.1% | 87,854 | $4.8M |
| Affinity Asset Advisors, LLC | 0.21% | Reduce -50.0% | 75,000 | $4.1M |
| PFM Health Sciences, LP | 0.34% | Reduce -1.3% | 70,971 | $3.9M |
| Boothbay Fund Management, LLC | 0.08% | Reduce -66.2% | 70,353 | $3.9M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -27.1% | 66,112 | $3.6M |
| Moore Capital Management, LP | 0.08% | New | 64,893 | $3.6M |
| Rhenman & Partners Asset Management AB | 0.32% | New | 62,000 | $3.4M |
| Invesco Ltd. | 0.00% | Add +84.1% | 50,678 | $2.8M |
| Alps Advisors Inc. | 0.01% | Add +31.4% | 48,012 | $2.7M |
| Platinum Investment Management Ltd. | 0.59% | No change | 43,597 | $2.4M |
| Swiss National Bank | 0.00% | Reduce -3.4% | 42,900 | $2.4M |
| Ensign Peak Advisors, Inc | 0.00% | New | 42,156 | $2.3M |
| Algert Global LLC | 0.03% | Add +16.8% | 42,070 | $2.3M |
| Creative Planning | 0.00% | Add +9.9% | 39,524 | $2.2M |
| Rhumbline Advisers | 0.00% | Add +9.8% | 37,196 | $2.1M |
| Deutsche Bank AG | 0.00% | Add +38.1% | 31,693 | $1.7M |
| Wells Fargo & Company | 0.00% | Add +163.1% | 28,313 | $1.6M |
| Exchange Traded Concepts, LLC | 0.01% | Reduce -20.0% | 27,421 | $1.5M |
| Susquehanna International Group, LLP | 0.00% | Add +181.3% | 26,684 | $1.5M |
| Voya Investment Management LLC | 0.00% | New | 26,132 | $1.4M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | New | 25,800 | $1.4M |
| Teachers Retirement System of the State of Kentucky | 0.01% | New | 25,377 | $1.4M |
| Citigroup Inc. | 0.00% | Add +86.1% | 25,122 | $1.4M |
| California State Teachers Retirement System | 0.00% | Add +2.7% | 23,376 | $1.3M |
| American Century Companies Inc. | 0.00% | Add +159.9% | 22,680 | $1.3M |
| AQR Capital Management | 0.00% | Reduce -17.5% | 22,591 | $1.2M |
| Legal & General Group Plc | 0.00% | Add +11.5% | 21,583 | $1.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +194.9% | 21,344 | $1.2M |
| Cerity Partners LLC | 0.00% | Reduce -0.8% | 20,997 | $1.2M |
| Vanguard Global Advisers, LLC | 0.00% | Add +18.4% | 18,969 | $1.0M |
| MetLife Investment Management, LLC | 0.00% | Add +13.9% | 18,250 | $1.0M |
| Russell Investments Group, Ltd. | 0.00% | Add +371.0% | 18,162 | $1.0M |
| Koa Wealth Management, LLC | 0.64% | Reduce -4.5% | 17,113 | $945K |
| Alliancebernstein L.P. | 0.00% | Add +1.6% | 31,000 | $925K |
| State of Wisconsin Investment Board | 0.00% | Reduce -17.1% | 15,971 | $882K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | No change | 14,752 | $814K |
| Optimize Financial Inc. | 0.29% | Reduce -0.3% | 14,458 | $798K |
| Sound Capital Solutions LLC | 0.19% | — | 14,458 | $798K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +7.3% | 14,292 | $789K |
| DAFNA Capital Management LLC | 0.12% | Reduce -93.3% | 11,809 | $652K |
| HighVista Strategies LLC | 0.15% | Add +1.4% | 11,634 | $642K |
| New York State Common Retirement Fund | 0.00% | Add +22.2% | 11,000 | $607K |
| Jupiter Topco LLC | 0.00% | — | 10,300 | $568K |
| Fred Alger Management, LLC | 0.00% | New | 9,877 | $545K |
| BNP Paribas Financial Markets | 0.00% | Reduce -5.0% | 9,860 | $544K |
| State Board of Administration of Florida Retirement System | 0.00% | New | 9,777 | $540K |
| Virtus Investment Advisers, LLC | 0.12% | Add +0.9% | 9,215 | $509K |
"% of holder's portfolio" is MBX's weight in each manager's 13F, not the share of MBX Biosciences Inc. the manager owns.