Deerfield Management Company, L.P.
In its 13F for Q1 2024 (holdings as of March 31, 2024, filed May 15, 2024), Deerfield Management Company, L.P. reported 353 stock positions worth $5.2 billion. Its top holding was Nuvalent Class A (NUVL) at 28.8% of the portfolio, followed by Viatris (VTRS, 4.9%) and Centene (CNC, 3.6%). Compared with Q4 2023, it opened 223 new positions, sold out of 76, added to 64 and reduced 45. The biggest buy was Larimar Therapeutics (LRMR, shares +25%) and the biggest sale an exit from Rayzebio (RYZB).
- Most Recent 13F
- Q2 2026
- Location
- New York, NY
- CIK
- 0001009258
- Portfolio Value
- $5.2B (Q1 2024)
- SEC Filing
- 0000950159-24-000176 ↗ filed May 15, 2024
Holdings Value
Holdings 353 stocks · $5.2B
| NUVL Nuvalent Inc. Class A | 28.80% | 19,991,024 | $1.5B | No change |
| VTRS Viatris Inc. | 4.90% | 21,395,052 | $255.5M | Add +7.7% |
| CNC Centene Corp. | 3.58% | 2,381,044 | $186.9M | Add +19.5% |
| LRMR Larimar Therapeutics Inc. | 3.09% | 21,231,974 | $161.2M | Add +25.3% |
| AHCO Adapthealth Corp. | 2.93% | 13,257,940 | $152.6M | Reduce -2.6% |
| CPRX Catalyst Pharmaceuticals Inc. | 2.79% | 9,130,817 | $145.5M | Add +2.7% |
| OSCR Oscar Health Inc. Class A | 2.67% | 9,373,097 | $139.4M | Reduce -16.7% |
| FUSN Fusion Pharmaceuticals Inc. | 2.62% | 6,401,000 | $136.5M | No change |
| ACH Accendra Health Inc. filed as OWENS & MINOR INC NEW | 2.59% | 4,877,588 | $135.2M | Reduce -6.7% |
| MRUS Merus NV | 2.29% | 2,649,401 | $119.3M | Reduce -12.3% |
| KURA Kura Oncology Inc. | 2.21% | 5,411,571 | $115.4M | Add +1.9% |
| IDYA Ideaya Biosciences Inc. | 2.21% | 2,630,292 | $115.4M | No change |
| SPRY Ars Pharmaceuticals Inc. | 2.17% | 11,077,927 | $113.2M | No change |
| BKD Brookdale Senior Living Inc. | 1.98% | 15,612,264 | $103.2M | Add +5.5% |
| RVMD Revolution Medicines Inc. | 1.91% | 3,090,073 | $99.6M | No change |
| NBIX Neurocrine Biosciences Inc. | 1.83% | 691,004 | $95.3M | Reduce -22.9% |
| SGRY Surgery Partners Inc. | 1.82% | 3,186,803 | $95.1M | Add +51.4% |
| DCPH Deciphera Pharmaceuticals Inc. | 1.55% | 5,127,270 | $80.7M | Reduce -11.4% |
| HLVX Hillevax Inc. | 1.28% | 4,004,231 | $66.6M | No change |
| SWTX Springworks Therapeutics Inc. | 1.21% | 1,283,176 | $63.2M | Reduce -50.4% |
| EHAB Enhabit Inc. | 1.12% | 4,997,746 | $58.2M | No change |
| NKTX Nkarta Inc. | 1.08% | 5,194,087 | $56.1M | Add +52.8% |
| BIO Bio-Rad Laboratories-A | 1.01% | 152,378 | $52.7M | Add +0.5% |
| BNTX Biontech SE-ADR | 1.01% | 569,574 | $52.5M | New |
| EWTX Edgewise Therapeutics Inc. | 1.01% | 2,874,586 | $52.4M | Reduce -26.9% |
| IART Integra Lifesciences Holding | 1.00% | 1,473,090 | $52.2M | Add +30.5% |
| LKFT Lakefront Biotherapeutic-ADR filed as GALAPAGOS NV | 0.87% | 1,411,000 | $45.4M | Add +126.8% |
| GPCR Structure Therapeutics Inc. | 0.85% | 1,033,680 | $44.3M | Add +25.6% |
| IRON Disc Medicine Inc. | 0.79% | 665,535 | $41.4M | Add +43.3% |
| ALHC Alignment Healthcare Inc. | 0.79% | 8,270,697 | $41.0M | Add +137.1% |
| VKTX Viking Therapeutics Inc. | 0.73% | 463,501 | $38.0M | Reduce -63.8% |
| KYTX Kyverna Therapeutics Inc. | 0.70% | 1,462,337 | $36.3M | New |
| EMBC Embecta Corp. | 0.69% | 2,726,135 | $36.2M | Add +96.9% |
| CATX Perspective Therapeutics Inc. | 0.64% | 28,177,636 | $33.5M | New |
| SLDB Solid Biosciences Inc. | 0.58% | 2,260,398 | $30.1M | New |
| DAWN Day One Biopharmaceuticals I | 0.56% | 1,765,312 | $29.2M | Add +0.2% |
| CNMD Conmed Corp. | 0.52% | 338,165 | $27.1M | Add +13130.2% |
| BCRX Biocryst Pharmaceuticals Inc. | 0.49% | 4,995,000 | $25.4M | Add +10.0% |
| INMD Inmode Ltd. | 0.48% | 1,166,704 | $25.2M | New |
| ACCD Accolade Inc. | 0.48% | 2,382,102 | $25.0M | New |
| PHVS Pharvaris NV | 0.47% | 1,061,592 | $24.5M | Add +30.7% |
| AUTL Autolus Therapeutics PLC | 0.45% | 3,639,000 | $23.2M | New |
| APGE Apogee Therapeutics Inc. | 0.42% | 329,000 | $21.9M | New |
| CABA Cabaletta Bio Inc. | 0.41% | 1,258,650 | $21.5M | Reduce -37.3% |
| DCGO Docgo Inc. | 0.40% | 5,104,387 | $20.6M | Reduce -4.1% |
| CSTL Castle Biosciences Inc. | 0.39% | 928,017 | $20.6M | Reduce -3.9% |
| PRLD Prelude Therapeutics Inc. | 0.38% | 4,133,000 | $19.6M | No change |
| VTYX Ventyx Biosciences Inc. | 0.37% | 3,542,000 | $19.5M | New |
| CGEM Cullinan Therapeutics Inc. | 0.37% | 1,138,531 | $19.4M | New |
| PODD Insulet Corp. | 0.36% | 110,061 | $18.9M | Reduce -38.5% |
| VSTM Verastem Inc. | 0.35% | 1,538,461 | $18.2M | No change |
| QDEL Quidelortho Corp. | 0.32% | 348,000 | $16.7M | No change |
| GH Guardant Health Inc. | 0.31% | 791,735 | $16.3M | No change |
| FATE Fate Therapeutics Inc. | 0.31% | 2,190,408 | $16.1M | New |
| NAMS Newamsterdam Pharma Co. NV | 0.30% | 667,000 | $15.8M | New |
| LNTH Lantheus Holdings Inc. | 0.29% | 240,187 | $14.9M | New |
| ENGN Engene Holdings Inc. | 0.26% | 800,000 | $13.6M | New |
| TNGX Tango Therapeutics Inc. | 0.23% | 1,540,000 | $12.2M | No change |
| EYPT Eyepoint Inc. | 0.23% | 579,594 | $12.0M | New |
| COGT Cogent Biosciences Inc. | 0.20% | 1,534,345 | $10.3M | Add +40.9% |
| ITOS Iteos Therapeutics Inc. | 0.19% | 723,000 | $9.9M | No change |
| REPL Replimune Group Inc. | 0.13% | 802,984 | $6.6M | Reduce -55.7% |
| ALEC Alector Inc. | 0.12% | 1,072,845 | $6.5M | Add +0.5% |
| PRME Prime Medicine Inc. | 0.12% | 885,314 | $6.2M | No change |
| GUTS Fractyl Health Inc. | 0.12% | 834,254 | $6.2M | New |
| WGS Genedx Holdings Corp. | 0.11% | 643,110 | $5.9M | No change |
| STLN Starling Oncology Inc. filed as THE ONCOLOGY INSTITUTE INC | 0.10% | 3,360,052 | $5.3M | No change |
| ANNX Annexon Inc. | 0.08% | 583,913 | $4.2M | No change |
| CALC Calcimedica Inc. | 0.08% | 1,000,000 | $4.2M | New |
| VIGL Vigil Neuroscience Inc. | 0.06% | 980,311 | $3.3M | Reduce -16.5% |
| BIOMX INC | 0.05% | 6,110,098 | $2.7M | New |
| SINGULAR GENOMICS SYSTEMS IN | 0.05% | 4,984,871 | $2.6M | No change |
| CMAXQ Caremax Inc. | 0.05% | 529,108 | $2.6M | No change |
| CGON CG Oncology Inc. | 0.04% | 47,540 | $2.1M | New |
| DXC DXC Technology Co. | 0.03% | 62,245 | $1.3M | New |
| DRI Darden Restaurants Inc. | 0.02% | 6,335 | $1.1M | New |
| PRGS Progress Software Corp. | 0.02% | 19,394 | $1.0M | New |
| AMZN Amazon.com Inc. | 0.02% | 5,219 | $941K | Add +121.0% |
| EA Electronic Arts Inc. | 0.02% | 6,602 | $876K | New |
| APG Api Group Corp. | 0.02% | 22,264 | $874K | New |
| NVDA Nvidia Corp. | 0.02% | 949 | $857K | Reduce -17.2% |
| SNX TD Synnex Corp. | 0.02% | 7,188 | $813K | New |
| PII Polaris Inc. | 0.02% | 7,960 | $797K | New |
| OWL Blue Owl Capital Inc. | 0.02% | 41,712 | $787K | Add +129.0% |
| MNKD Mannkind Corp. | 0.01% | 167,278 | $758K | New |
| NABL N-Able Inc. | 0.01% | 57,956 | $757K | Add +315.8% |
| WHR Whirlpool Corp. | 0.01% | 6,147 | $735K | New |
| SKYT Skywater Technology Inc. | 0.01% | 71,580 | $728K | New |
| ZTS Zoetis Inc. | 0.01% | 4,189 | $709K | New |
| DRS Leonardo DRS Inc. | 0.01% | 31,888 | $704K | New |
| CDMO Avid Bioservices Inc. | 0.01% | 101,789 | $682K | Add +157.2% |
| FCN Fti Consulting Inc. | 0.01% | 3,242 | $682K | New |
| AGYS Agilysys Inc. | 0.01% | 7,999 | $674K | New |
| ACLS Axcelis Technologies Inc. | 0.01% | 5,969 | $666K | New |
| ITW Illinois Tool Works | 0.01% | 2,470 | $663K | Add +194.8% |
| AMED Amedisys Inc. | 0.01% | 6,978 | $643K | New |
| ATRC Atricure Inc. | 0.01% | 20,740 | $631K | New |
| PAG Penske Automotive Group Inc. | 0.01% | 3,859 | $625K | New |
| FTNT Fortinet Inc. | 0.01% | 9,021 | $616K | New |
| GTLS Chart Industries Inc. | 0.01% | 3,720 | $613K | New |
Other holdings (14): bonds, preferreds, convertibles and warrants · $535.1M (not counted above)
| Security | Class | Shares / Principal | Value | Change |
|---|---|---|---|---|
| BROOKDALE SENIOR LIVING (BKD 2 10/15/26) | NOTE 2.000%10/1 · principal | 161,905,000 | $158.4M | Add +10.9% |
| INSMED INC (INSM 1.75 01/15/25) | NOTE 1.750% 1/1 · principal | 116,954,000 | $124.4M | No change |
| ACCOLADE INC (ACCD 0.5 04/01/26) | NOTE 0.500% 4/0 · principal | 132,598,000 | $117.5M | No change |
| INTEGRA LIFESCIENCES HLD (IART 0.5 08/15/25) | NOTE 0.500% 8/1 · principal | 103,215,000 | $98.7M | New |
| LANTHEUS HOLDINGS INC (LNTH 2.625 12/15/27) | NOTE 2.625%12/1 · principal | 25,255,000 | $28.0M | New |
| NEOGENOMICS INC (NEO 1.25 05/01/25) | NOTE 1.250% 5/0 · principal | 6,500,000 | $6.3M | No change |
| NAMSW Newamsterdam Pharma Co. NV-27 | *W EXP 99/99/999 | 92,787 | $1.0M | No change |
| TLSIW Medtech Acquisition Corp.-CW | *W EXP 08/10/202 | 333,333 | $333K | No change |
| STLNW Oncology Institute Inc. CW-22 | *W EXP 99/99/999 | 1,250,000 | $250K | No change |
| QSIAW Quantum-Si Inc. -CW27 | *W EXP 06/10/202 | 333,333 | $81K | No change |
| NUVB.WS Nuvation Bio Inc. -CW27 | *W EXP 02/10/202 | 166,666 | $50K | No change |
| BFLYW Butterfly Network Inc. -CW25 | *W EXP 02/12/202 | 733,333 | $33K | No change |
| CMXWQ Caremax-CW | *W EXP 06/08/202 | 672,000 | $11K | No change |
| SRZNW Surrozen Inc.-CW25 | *W EXP 08/01/203 | 166,666 | $5K | No change |
Total filed on the 13F, all lines: $5.7B.
Portfolio Sells Q4 2023 → Q1 2024
| RYZB Rayzebio Inc. | Sold out | 0.00% | −1.47 |
| BAX Baxter International Inc. | Reduce -99.5% | 0.01% | −1.23 |
| SWTX Springworks Therapeutics Inc. | Reduce -50.4% | 1.21% | −1.00 |
| NBIX Neurocrine Biosciences Inc. | Reduce -22.9% | 1.83% | −0.94 |
| CABA Cabaletta Bio Inc. | Reduce -37.3% | 0.41% | −0.66 |
| DCPH Deciphera Pharmaceuticals Inc. | Reduce -11.4% | 1.55% | −0.64 |
| PODD Insulet Corp. | Reduce -38.5% | 0.36% | −0.55 |
| DCGO Docgo Inc. | Reduce -4.1% | 0.40% | −0.30 |
| REPL Replimune Group Inc. | Reduce -55.7% | 0.13% | −0.23 |
| CSTL Castle Biosciences Inc. | Reduce -3.9% | 0.39% | −0.09 |
| VIGL Vigil Neuroscience Inc. | Reduce -16.5% | 0.06% | −0.03 |
| NYXH Nyxoah SA | Sold out | 0.00% | −0.02 |
| TRS Trimas Corp. | Sold out | 0.00% | −0.01 |
| PPC Pilgrim's Pride Corp. | Sold out | 0.00% | −0.01 |
| JNJ Johnson & Johnson | Sold out | 0.00% | −0.01 |
| MUR Murphy Oil Corp. | Sold out | 0.00% | −0.01 |
| ANDE The Andersons Inc. | Sold out | 0.00% | −0.01 |
| METC Ramaco Resources Inc. Class A | Reduce -54.8% | 0.01% | −0.01 |
| DXCM Dexcom Inc. | Sold out | 0.00% | −0.01 |
| MLAB Mesa Laboratories Inc. | Sold out | 0.00% | −0.01 |
| JNPR Juniper Networks Inc. | Sold out | 0.00% | −0.01 |
| HSTM Healthstream Inc. | Sold out | 0.00% | −0.01 |
| IDCC Interdigital Inc. | Sold out | 0.00% | −0.01 |
| EEFT Euronet Worldwide Inc. | Sold out | 0.00% | −0.01 |
| MCS Marcus Corporation | Sold out | 0.00% | −0.01 |
| SMP Standard Motor Prods | Sold out | 0.00% | −0.01 |
| AVY Avery Dennison Corp. | Sold out | 0.00% | −0.01 |
| FMC FMC Corp. | Sold out | 0.00% | −0.01 |
| DVA Davita Inc. | Sold out | 0.00% | −0.01 |
| AROC Archrock Inc. | Sold out | 0.00% | −0.01 |
| UVE Universal Insurance Holdings | Sold out | 0.00% | −0.01 |
| CTRE Caretrust REIT Inc. | Sold out | 0.00% | −0.01 |
| MRK Merck & Co. Inc. | Sold out | 0.00% | −0.01 |
| UTZ Utz Brands Inc. | Sold out | 0.00% | −0.01 |
| MSA Msa Safety Inc. | Reduce -43.0% | 0.01% | −0.01 |
| KWR Quaker Chemical Corporation | Sold out | 0.00% | −0.01 |
| WWD Woodward Inc. | Reduce -59.5% | 0.00% | −0.01 |
| ACAD Acadia Pharmaceuticals Inc. | Sold out | 0.00% | −0.01 |
| ALNY Alnylam Pharmaceuticals Inc. | Sold out | 0.00% | −0.01 |
| IPG Interpublic Group of Cos Inc. | Sold out | 0.00% | −0.01 |
| MDGL Madrigal Pharmaceuticals Inc. | Sold out | 0.00% | −0.01 |
| TGT Target Corp. | Sold out | 0.00% | −0.01 |
| SAH Sonic Automotive Inc. Class A | Sold out | 0.00% | −0.01 |
| MMS Maximus Inc. | Reduce -53.5% | 0.00% | −0.01 |
| VC Visteon Corp. | Reduce -44.6% | 0.00% | −0.01 |
| ADM Archer-Daniels-Midland Co. | Sold out | 0.00% | −0.01 |
| NUE Nucor Corp. | Sold out | 0.00% | −0.01 |
| ARVN Arvinas Inc. | Sold out | 0.00% | −0.01 |
| VGR Vector Group Ltd. | Sold out | 0.00% | −0.01 |
| BDN Brandywine Realty Trust | Sold out | 0.00% | −0.01 |
Portfolio Buys Q4 2023 → Q1 2024
| LRMR Larimar Therapeutics Inc. | Add +25.3% | 3.09% | +1.28 |
| BNTX Biontech SE-ADR | New | 1.01% | +1.01 |
| KYTX Kyverna Therapeutics Inc. | New | 0.70% | +0.70 |
| CATX Perspective Therapeutics Inc. | New | 0.64% | +0.64 |
| SLDB Solid Biosciences Inc. | New | 0.58% | +0.58 |
| NKTX Nkarta Inc. | Add +52.8% | 1.08% | +0.55 |
| CNMD Conmed Corp. | Add +13130.2% | 0.52% | +0.51 |
| INMD Inmode Ltd. | New | 0.48% | +0.48 |
| ACCD Accolade Inc. | New | 0.48% | +0.48 |
| AUTL Autolus Therapeutics PLC | New | 0.45% | +0.45 |
| KURA Kura Oncology Inc. | Add +1.9% | 2.21% | +0.42 |
| APGE Apogee Therapeutics Inc. | New | 0.42% | +0.42 |
| VTYX Ventyx Biosciences Inc. | New | 0.37% | +0.37 |
| CGEM Cullinan Therapeutics Inc. | New | 0.37% | +0.37 |
| FATE Fate Therapeutics Inc. | New | 0.31% | +0.31 |
| NAMS Newamsterdam Pharma Co. NV | New | 0.30% | +0.30 |
| LNTH Lantheus Holdings Inc. | New | 0.29% | +0.29 |
| LKFT Lakefront Biotherapeutic-ADR | Add +126.8% | 0.87% | +0.28 |
| ENGN Engene Holdings Inc. | New | 0.26% | +0.26 |
| SGRY Surgery Partners Inc. | Add +51.4% | 1.82% | +0.24 |
| EYPT Eyepoint Inc. | New | 0.23% | +0.23 |
| IRON Disc Medicine Inc. | Add +43.3% | 0.79% | +0.17 |
| GUTS Fractyl Health Inc. | New | 0.12% | +0.12 |
| CNC Centene Corp. | Add +19.5% | 3.58% | +0.12 |
| ALHC Alignment Healthcare Inc. | Add +137.1% | 0.79% | +0.08 |
| CALC Calcimedica Inc. | New | 0.08% | +0.08 |
| EMBC Embecta Corp. | Add +96.9% | 0.69% | +0.08 |
| GPCR Structure Therapeutics Inc. | Add +25.6% | 0.85% | +0.06 |
| BIOMX INC | New | 0.05% | +0.05 |
| COGT Cogent Biosciences Inc. | Add +40.9% | 0.20% | +0.05 |
| CGON CG Oncology Inc. | New | 0.04% | +0.04 |
| DXC DXC Technology Co. | New | 0.03% | +0.03 |
| DRI Darden Restaurants Inc. | New | 0.02% | +0.02 |
| PRGS Progress Software Corp. | New | 0.02% | +0.02 |
| APG Api Group Corp. | New | 0.02% | +0.02 |
| EA Electronic Arts Inc. | New | 0.02% | +0.02 |
| SNX TD Synnex Corp. | New | 0.02% | +0.02 |
| PII Polaris Inc. | New | 0.02% | +0.02 |
| MNKD Mannkind Corp. | New | 0.01% | +0.01 |
| WHR Whirlpool Corp. | New | 0.01% | +0.01 |
| SKYT Skywater Technology Inc. | New | 0.01% | +0.01 |
| ZTS Zoetis Inc. | New | 0.01% | +0.01 |
| DRS Leonardo DRS Inc. | New | 0.01% | +0.01 |
| FCN Fti Consulting Inc. | New | 0.01% | +0.01 |
| AGYS Agilysys Inc. | New | 0.01% | +0.01 |
| ACLS Axcelis Technologies Inc. | New | 0.01% | +0.01 |
| AMED Amedisys Inc. | New | 0.01% | +0.01 |
| ATRC Atricure Inc. | New | 0.01% | +0.01 |
| PAG Penske Automotive Group Inc. | New | 0.01% | +0.01 |
| GTLS Chart Industries Inc. | New | 0.01% | +0.01 |
Notes & Other Activity Q4 2023 → Q1 2024
| GLAUKOS CORP (GKOS 2.75 06/15/27) | NOTE 2.750% 6/1 · principal | Sold out | 271,452,000 | $414.9Mbefore exit |
| INVITAE CORP (NVTA 4.5 03/15/28 A) | DEBT 4.500% 3/1 · principal | Sold out | 217,766,000 | $187.0Mbefore exit |
| NATERA INC (NTRA 2.25 05/01/27) | NOTE 2.250% 5/0 · principal | Sold out | 101,042,000 | $172.4Mbefore exit |
| BROOKDALE SENIOR LIVING (BKD 2 10/15/26) | NOTE 2.000%10/1 · principal | Add +10.9% | 161,905,000 | $158.4M |
| INTEGRA LIFESCIENCES HLD (IART 0.5 08/15/25) | NOTE 0.500% 8/1 · principal | New | 103,215,000 | $98.7M |
| LANTHEUS HOLDINGS INC (LNTH 2.625 12/15/27) | NOTE 2.625%12/1 · principal | New | 25,255,000 | $28.0M |
| SOMALOGIC INC | *W EXP 08/31/202 | Sold out | 120,000 | $14Kbefore exit |
Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.
All Filings
| Quarter | Positions | 13F Reported Value | Top Holdings |
|---|---|---|---|
| Q2 2026 | 69 | $8.0B | NUVL, RVMD, PRAX, VTRS, CNC |
| Q1 2026 | 69 | $7.2B | NUVL, COGT, PRAX, VTRS, UTHR |
| Q4 2025 | 135 | $6.8B | NUVL, COGT, PRAX, CNC, VTRS |
| Q3 2025 | 138 | $6.0B | NUVL, CNC, MRUS, VTRS, UTHR |
| Q2 2025 | 110 | $4.9B | NUVL, OSCR, VTRS, MRUS, CNC |
| Q1 2025 | 109 | $4.4B | NUVL, VTRS, NBIX, CNC, OSCR |
| Q4 2024 | 93 | $4.7B | NUVL, VTRS, CNC, OSCR, RVMD |
| Q3 2024 | 430 | $6.0B | NUVL, VTRS, CNC, MRUS, OSCR |
| Q2 2024 | 418 | $5.2B | NUVL, VTRS, CNC, MRUS, LRMR |
| Q1 2024 | 353 | $5.2B | NUVL, VTRS, CNC, LRMR, AHCO |