Deerfield Management Company, L.P.

In its 13F for Q2 2024 (holdings as of June 30, 2024, filed August 14, 2024), Deerfield Management Company, L.P. reported 418 stock positions worth $5.2 billion. Its top holding was Nuvalent Class A (NUVL) at 29.3% of the portfolio, followed by Viatris (VTRS, 4.4%) and Centene (CNC, 3.4%). Compared with Q1 2024, it opened 225 new positions, sold out of 160, added to 125 and reduced 41. The biggest buy was a new position in Waystar (WAY) and the biggest sale an exit from Fusion Pharmaceuticals (FUSN).

Most Recent 13F
Q2 2026
Location
New York, NY
CIK
0001009258
Portfolio Value
$5.2B (Q2 2024)
SEC Filing
0000950159-24-000249 ↗ filed Aug 14, 2024

Holdings Value

0$2.0B$4.0B$6.0B$8.0B$10.0B Q1 2024: $5.2B Q1 2024 Q2 2024: $5.2B $5.2B Q2 2024 Q3 2024: $6.0B Q3 2024 Q4 2024: $4.7B Q4 2024 Q1 2025: $4.4B Q1 2025 Q2 2025: $4.9B Q2 2025 Q3 2025: $6.0B Q3 2025 Q4 2025: $6.8B Q4 2025 Q1 2026: $7.2B Q1 2026 Q2 2026: $8.0B Q2 2026

Holdings 418 stocks · $5.2B

NUVL Nuvalent Inc. Class A 29.30% 19,991,024 $1.5B No change
VTRS Viatris Inc. 4.39% 21,395,496 $227.4M Add +0.0%
CNC Centene Corp. 3.40% 2,650,122 $175.7M Add +11.3%
MRUS Merus NV 3.14% 2,749,401 $162.7M Add +3.8%
LRMR Larimar Therapeutics Inc. 2.97% 21,231,974 $153.9M No change
CPRX Catalyst Pharmaceuticals Inc. 2.73% 9,127,305 $141.4M Reduce -0.0%
AHCO Adapthealth Corp. 2.56% 13,257,940 $132.6M No change
RVMD Revolution Medicines Inc. 2.32% 3,090,073 $119.9M No change
SGRY Surgery Partners Inc. 2.16% 4,707,287 $112.0M Add +47.7%
KURA Kura Oncology Inc. 2.15% 5,411,571 $111.4M No change
OSCR Oscar Health Inc. Class A 2.13% 6,959,787 $110.1M Reduce -25.8%
BKD Brookdale Senior Living Inc. 2.06% 15,612,264 $106.6M No change
WAY Waystar Holding Corp. 2.06% 4,952,004 $106.5M New
GILD Gilead Sciences Inc. 1.98% 1,491,000 $102.3M New
NBIX Neurocrine Biosciences Inc. 1.84% 691,004 $95.1M No change
SPRY Ars Pharmaceuticals Inc. 1.82% 11,077,927 $94.3M No change
ACH Accendra Health Inc. filed as OWENS & MINOR INC NEW 1.66% 6,371,440 $86.0M Add +30.6%
ALHC Alignment Healthcare Inc. 1.65% 10,901,485 $85.2M Add +31.8%
IDYA Ideaya Biosciences Inc. 1.42% 2,097,113 $73.6M Reduce -20.3%
HLVX Hillevax Inc. 1.12% 4,004,231 $57.9M No change
CVS CVS Health Corp. 1.11% 975,000 $57.6M New
CGEM Cullinan Therapeutics Inc. 1.11% 3,280,237 $57.2M Add +188.1%
BAX Baxter International Inc. 1.02% 1,577,647 $52.8M Add +25590.4%
EWTX Edgewise Therapeutics Inc. 1.00% 2,874,586 $51.8M No change
BCRX Biocryst Pharmaceuticals Inc. 0.97% 8,135,804 $50.3M Add +62.9%
BNTX Biontech SE-ADR 0.92% 594,000 $47.7M Add +4.3%
IRON Disc Medicine Inc. 0.89% 1,023,265 $46.1M Add +53.8%
EHAB Enhabit Inc. 0.86% 4,997,746 $44.6M No change
CNMD Conmed Corp. 0.85% 631,264 $43.8M Add +86.7%
IART Integra Lifesciences Holding 0.83% 1,467,632 $42.8M Reduce -0.4%
BIO Bio-Rad Laboratories-A 0.80% 151,714 $41.4M Reduce -0.4%
DAWN Day One Biopharmaceuticals I 0.78% 2,923,137 $40.3M Add +65.6%
LKFT Lakefront Biotherapeutic-ADR filed as GALAPAGOS NV 0.68% 1,411,000 $35.0M No change
EMBC Embecta Corp. 0.66% 2,726,135 $34.1M No change
GPCR Structure Therapeutics Inc. 0.64% 844,407 $33.2M Reduce -18.3%
COGT Cogent Biosciences Inc. 0.61% 3,744,263 $31.6M Add +144.0%
ALNY Alnylam Pharmaceuticals Inc. 0.56% 119,800 $29.1M New
CATX Perspective Therapeutics Inc. 0.54% 2,817,763 $28.1M New
PHVS Pharvaris NV 0.51% 1,397,279 $26.3M Add +31.6%
MREO Mereo Biopharma Group PL-ADR 0.47% 6,710,429 $24.2M New
PODD Insulet Corp. 0.44% 112,433 $22.7M Add +2.2%
NKTX Nkarta Inc. 0.43% 3,799,143 $22.5M Reduce -26.9%
DCGO Docgo Inc. 0.43% 7,195,956 $22.2M Add +41.0%
INMD Inmode Ltd. 0.41% 1,166,704 $21.3M No change
PACS Pacs Group Inc. 0.38% 663,851 $19.6M New
LNTH Lantheus Holdings Inc. 0.37% 240,218 $19.3M Add +0.0%
CSTL Castle Biosciences Inc. 0.37% 874,609 $19.0M Reduce -5.8%
NAMS Newamsterdam Pharma Co. NV 0.32% 869,250 $16.7M Add +30.3%
PRLD Prelude Therapeutics Inc. 0.30% 4,133,000 $15.7M No change
KYTX Kyverna Therapeutics Inc. 0.29% 1,983,000 $14.9M Add +35.6%
FHTX Foghorn Therapeutics Inc. 0.28% 2,518,500 $14.5M New
CGON CG Oncology Inc. 0.26% 433,540 $13.7M Add +812.0%
VTYX Ventyx Biosciences Inc. 0.26% 5,829,570 $13.5M Add +64.6%
TNGX Tango Therapeutics Inc. 0.26% 1,540,000 $13.2M No change
APGE Apogee Therapeutics Inc. 0.25% 329,000 $12.9M No change
AUTL Autolus Therapeutics PLC 0.24% 3,639,000 $12.7M No change
ACCD Accolade Inc. 0.24% 3,475,000 $12.4M Add +45.9%
FATE Fate Therapeutics Inc. 0.23% 3,555,871 $11.7M Add +62.3%
TXG 10X Genomics Inc. Class A 0.22% 597,000 $11.6M New
ITOS Iteos Therapeutics Inc. 0.21% 723,000 $10.7M No change
SLDB Solid Biosciences Inc. 0.19% 1,743,398 $9.9M Reduce -22.9%
EYPT Eyepoint Inc. 0.15% 877,790 $7.6M Add +51.5%
ALEC Alector Inc. 0.10% 1,148,326 $5.2M Add +7.0%
PRME Prime Medicine Inc. 0.09% 896,960 $4.6M Add +1.3%
PHR Phreesia Inc. 0.08% 192,347 $4.1M New
CALC Calcimedica Inc. 0.08% 1,000,000 $4.0M No change
GUTS Fractyl Health Inc. 0.07% 834,254 $3.6M No change
CABA Cabaletta Bio Inc. 0.07% 464,252 $3.5M Reduce -63.1%
ANNX Annexon Inc. 0.06% 583,913 $2.9M No change
AEROVATE THERAPEUTICS INC 0.05% 1,411,608 $2.3M New
KWR Quaker Chemical Corporation 0.04% 13,015 $2.2M New
DRI Darden Restaurants Inc. 0.04% 14,344 $2.2M Add +126.4%
JBL Jabil Inc. 0.04% 19,662 $2.1M New
BIOMX INC 0.04% 6,110,098 $2.1M No change
LOW Lowe's Cos Inc. 0.03% 8,113 $1.8M New
USAP Universal Stainless & Alloy 0.03% 65,060 $1.8M New
ZTS Zoetis Inc. 0.03% 10,078 $1.7M Add +140.6%
INOD Innodata Inc. 0.03% 111,814 $1.7M Add +309.5%
CVGW Calavo Growers Inc. 0.03% 70,514 $1.6M Add +566.9%
HUMA Humacyte Inc. 0.03% 322,851 $1.5M New
STLN Starling Oncology Inc. filed as THE ONCOLOGY INSTITUTE INC 0.03% 3,360,052 $1.5M No change
HXL Hexcel Corp. 0.03% 23,879 $1.5M Add +354.1%
CMAXQ Caremax Inc. 0.03% 530,232 $1.5M Add +0.2%
RMD Resmed Inc. 0.03% 7,576 $1.5M New
COO The Cooper Cos Inc. 0.03% 16,609 $1.4M Add +222.9%
MATW Matthews Intl Corp. Class A 0.03% 57,723 $1.4M Add +364.1%
INTU Intuit Inc. 0.03% 2,197 $1.4M New
CSV Carriage Services Inc. 0.03% 53,584 $1.4M Add +198.0%
TDY Teledyne Technologies Inc. 0.03% 3,656 $1.4M Add +274.6%
OMIC Singular Genomics Systems Inc. 0.03% 166,162 $1.4M No change
TMDX Transmedics Group Inc. 0.03% 9,298 $1.4M New
USNA Usana Health Sciences Inc. 0.03% 29,742 $1.3M Add +297.0%
CRMT America's Car-Mart Inc. 0.03% 22,267 $1.3M Add +459.9%
MAN Manpowergroup Inc. 0.03% 19,104 $1.3M Add +147.1%
VYX NCR Voyix Corp. 0.03% 107,398 $1.3M New
BCSF Bain Capital Specialty Finan 0.03% 79,569 $1.3M Add +213.8%
NVDA Nvidia Corp. 0.02% 10,400 $1.3M Add +9.6%
ZBRA Zebra Technologies Corp. Class A 0.02% 4,147 $1.3M New
RVTY Revvity Inc. 0.02% 12,058 $1.3M Add +200.5%
CDMO Avid Bioservices Inc. 0.02% 176,586 $1.3M Add +73.5%

Show all 418 holdings

Other holdings (15): bonds, preferreds, convertibles and warrants · $835.1M (not counted above)
SecurityClassShares / PrincipalValueChange
INSMED INC (INSM 1.75 01/15/25) NOTE 1.750% 1/1 · principal 151,408,000$258.7MAdd +29.5%
INTEGRA LIFESCIENCES HLD (IART 0.5 08/15/25) NOTE 0.500% 8/1 · principal 174,364,000$164.5MAdd +68.9%
BROOKDALE SENIOR LIVING (BKD 2 10/15/26) NOTE 2.000%10/1 · principal 161,905,000$163.3MNo change
ACCOLADE INC (ACCD 0.5 04/01/26) NOTE 0.500% 4/0 · principal 132,598,000$115.5MNo change
MIRUM PHARMACEUTICALS (MIRM 4 05/01/29) NOTE 4.000% 5/0 · principal 70,000,000$93.8MNew
LANTHEUS HOLDINGS INC (LNTH 2.625 12/15/27) NOTE 2.625%12/1 · principal 25,255,000$31.5MNo change
NEOGENOMICS INC (NEO 1.25 05/01/25) NOTE 1.250% 5/0 · principal 6,500,000$6.3MNo change
NAMSW Newamsterdam Pharma Co. NV-27 *W EXP 99/99/999 92,787$809KNo change
TLSIW Medtech Acquisition Corp.-CW *W EXP 08/10/202 333,333$543KNo change
QSIAW Quantum-Si Inc. -CW27 *W EXP 06/10/202 333,333$42KNo change
STLNW Oncology Institute Inc. CW-22 *W EXP 99/99/999 1,250,000$33KNo change
NUVB.WS Nuvation Bio Inc. -CW27 *W EXP 02/10/202 166,666$27KNo change
BFLYW Butterfly Network Inc. -CW25 *W EXP 02/12/202 733,333$17KNo change
CMXWQ Caremax-CW *W EXP 06/08/202 672,000$9KNo change
SRZNW Surrozen Inc.-CW25 *W EXP 08/01/203 166,666$3KNo change

Total filed on the 13F, all lines: $6.0B.

Portfolio Sells Q1 2024 → Q2 2024

FUSN Fusion Pharmaceuticals Inc. Sold out 0.00% −2.62
DCPH Deciphera Pharmaceuticals Inc. Sold out 0.00% −1.55
SWTX Springworks Therapeutics Inc. Sold out 0.00% −1.21
IDYA Ideaya Biosciences Inc. Reduce -20.3% 1.42% −0.79
VKTX Viking Therapeutics Inc. Sold out 0.00% −0.73
NKTX Nkarta Inc. Reduce -26.9% 0.43% −0.64
CATX Perspective Therapeutics Inc. Sold out 0.00% −0.64
OSCR Oscar Health Inc. Class A Reduce -25.8% 2.13% −0.55
SLDB Solid Biosciences Inc. Reduce -22.9% 0.19% −0.39
VSTM Verastem Inc. Sold out 0.00% −0.35
CABA Cabaletta Bio Inc. Reduce -63.1% 0.07% −0.34
QDEL Quidelortho Corp. Sold out 0.00% −0.32
GH Guardant Health Inc. Sold out 0.00% −0.31
ENGN Engene Holdings Inc. Sold out 0.00% −0.26
BIO Bio-Rad Laboratories-A Reduce -0.4% 0.80% −0.21
GPCR Structure Therapeutics Inc. Reduce -18.3% 0.64% −0.21
IART Integra Lifesciences Holding Reduce -0.4% 0.83% −0.18
REPL Replimune Group Inc. Reduce -96.3% 0.01% −0.12
WGS Genedx Holdings Corp. Sold out 0.00% −0.11
VIGL Vigil Neuroscience Inc. Sold out 0.00% −0.06
CPRX Catalyst Pharmaceuticals Inc. Reduce -0.0% 2.73% −0.06
CSTL Castle Biosciences Inc. Reduce -5.8% 0.37% −0.03
DXC DXC Technology Co. Reduce -78.1% 0.01% −0.02
AMZN Amazon.com Inc. Sold out 0.00% −0.02
APG Api Group Corp. Sold out 0.00% −0.02
EA Electronic Arts Inc. Sold out 0.00% −0.02
SNX TD Synnex Corp. Sold out 0.00% −0.02
PII Polaris Inc. Sold out 0.00% −0.02
NABL N-Able Inc. Sold out 0.00% −0.01
SKYT Skywater Technology Inc. Sold out 0.00% −0.01
DRS Leonardo DRS Inc. Sold out 0.00% −0.01
FCN Fti Consulting Inc. Sold out 0.00% −0.01
AMED Amedisys Inc. Sold out 0.00% −0.01
PAG Penske Automotive Group Inc. Sold out 0.00% −0.01
SRCL Stericycle Inc. Sold out 0.00% −0.01
V Visa Inc. Class A Sold out 0.00% −0.01
AAPL Apple Inc. Sold out 0.00% −0.01
SCI Service Corp. International Sold out 0.00% −0.01
SWKS Skyworks Solutions Inc. Sold out 0.00% −0.01
ENV Envestnet Inc. Sold out 0.00% −0.01
HCSG Healthcare Services Group Sold out 0.00% −0.01
IMNM Immunome Inc. Sold out 0.00% −0.01
OWL Blue Owl Capital Inc. Reduce -69.3% 0.00% −0.01
GCO Genesco Inc. Sold out 0.00% −0.01
BBY Best Buy Co. Inc. Sold out 0.00% −0.01
AMPY Amplify Energy Corp. Sold out 0.00% −0.01
BJ Bj's Wholesale Club Holdings Sold out 0.00% −0.01
AGIO Agios Pharmaceuticals Inc. Sold out 0.00% −0.01
EIG Employers Holdings Inc. Sold out 0.00% −0.01
GES Guess? Inc. Sold out 0.00% −0.01

Portfolio Buys Q1 2024 → Q2 2024

WAY Waystar Holding Corp. New 2.06% +2.06
GILD Gilead Sciences Inc. New 1.98% +1.98
CVS CVS Health Corp. New 1.11% +1.11
BAX Baxter International Inc. Add +25590.4% 1.02% +1.01
ALHC Alignment Healthcare Inc. Add +31.8% 1.65% +0.86
MRUS Merus NV Add +3.8% 3.14% +0.85
CGEM Cullinan Therapeutics Inc. Add +188.1% 1.11% +0.73
ALNY Alnylam Pharmaceuticals Inc. New 0.56% +0.56
CATX Perspective Therapeutics Inc. New 0.54% +0.54
BCRX Biocryst Pharmaceuticals Inc. Add +62.9% 0.97% +0.48
MREO Mereo Biopharma Group PL-ADR New 0.47% +0.47
COGT Cogent Biosciences Inc. Add +144.0% 0.61% +0.41
PACS Pacs Group Inc. New 0.38% +0.38
SGRY Surgery Partners Inc. Add +47.7% 2.16% +0.34
CNMD Conmed Corp. Add +86.7% 0.85% +0.33
FHTX Foghorn Therapeutics Inc. New 0.28% +0.28
CGON CG Oncology Inc. Add +812.0% 0.26% +0.22
TXG 10X Genomics Inc. Class A New 0.22% +0.22
DAWN Day One Biopharmaceuticals I Add +65.6% 0.78% +0.22
IRON Disc Medicine Inc. Add +53.8% 0.89% +0.10
LNTH Lantheus Holdings Inc. Add +0.0% 0.37% +0.09
PHR Phreesia Inc. New 0.08% +0.08
PODD Insulet Corp. Add +2.2% 0.44% +0.08
AEROVATE THERAPEUTICS INC New 0.05% +0.05
KWR Quaker Chemical Corporation New 0.04% +0.04
JBL Jabil Inc. New 0.04% +0.04
PHVS Pharvaris NV Add +31.6% 0.51% +0.04
LOW Lowe's Cos Inc. New 0.03% +0.03
USAP Universal Stainless & Alloy New 0.03% +0.03
DCGO Docgo Inc. Add +41.0% 0.43% +0.03
HUMA Humacyte Inc. New 0.03% +0.03
INOD Innodata Inc. Add +309.5% 0.03% +0.03
RMD Resmed Inc. New 0.03% +0.03
INTU Intuit Inc. New 0.03% +0.03
TMDX Transmedics Group Inc. New 0.03% +0.03
VYX NCR Voyix Corp. New 0.03% +0.03
CVGW Calavo Growers Inc. Add +566.9% 0.03% +0.03
ZBRA Zebra Technologies Corp. Class A New 0.02% +0.02
EPC Edgewell Personal Care Co. New 0.02% +0.02
AMAL Amalgamated Financial Corp. New 0.02% +0.02
YELP Yelp Inc. New 0.02% +0.02
AROC Archrock Inc. New 0.02% +0.02
KMT Kennametal Inc. New 0.02% +0.02
TTC Toro Co. New 0.02% +0.02
TFX Teleflex Inc. New 0.02% +0.02
OSG Octave Specialty Group Inc. New 0.02% +0.02
SNOW Snowflake Inc. New 0.02% +0.02
DRI Darden Restaurants Inc. Add +126.4% 0.04% +0.02
PRDO Perdoceo Education Corp. New 0.02% +0.02
HXL Hexcel Corp. Add +354.1% 0.03% +0.02

Notes & Other Activity Q1 2024 → Q2 2024

INSMED INC (INSM 1.75 01/15/25) NOTE 1.750% 1/1 · principal Add +29.5% 151,408,000 $258.7M
INTEGRA LIFESCIENCES HLD (IART 0.5 08/15/25) NOTE 0.500% 8/1 · principal Add +68.9% 174,364,000 $164.5M
MIRUM PHARMACEUTICALS (MIRM 4 05/01/29) NOTE 4.000% 5/0 · principal New 70,000,000 $93.8M

Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 69$8.0BNUVL, RVMD, PRAX, VTRS, CNC
Q1 2026 69$7.2BNUVL, COGT, PRAX, VTRS, UTHR
Q4 2025 135$6.8BNUVL, COGT, PRAX, CNC, VTRS
Q3 2025 138$6.0BNUVL, CNC, MRUS, VTRS, UTHR
Q2 2025 110$4.9BNUVL, OSCR, VTRS, MRUS, CNC
Q1 2025 109$4.4BNUVL, VTRS, NBIX, CNC, OSCR
Q4 2024 93$4.7BNUVL, VTRS, CNC, OSCR, RVMD
Q3 2024 430$6.0BNUVL, VTRS, CNC, MRUS, OSCR
Q2 2024 418$5.2BNUVL, VTRS, CNC, MRUS, LRMR
Q1 2024 353$5.2BNUVL, VTRS, CNC, LRMR, AHCO