Prelude TherapeuticsPRLD
13F holders, Q2 2026 (June 30)75holders +20
34new positions
13sold out
3famous investors
$5.33avg. 13F price*
At the end of Q2 2026, 75 institutions reported holding Prelude Therapeutics Inc. (PRLD) in their 13F filings, up 20 from Q1 2026. 34 opened new positions and 13 sold out. The largest holders were Orbimed Advisors LLC ($73.2M), Baker Bros. Advisors LP ($54.0M) and Ra Capital Management, L.P. ($34.5M). 3 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Prelude Therapeutics Inc.
- CUSIP
- 74065P101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 34 | $61.3M |
| Exits | 13 | $5.7M |
All 13F filers, Q1 2026 → Q2 2026: 20,927,327 shares bought and 2,099,763 shares sold, net +18,827,564 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 75 holders
| Orbimed Advisors LLC | 1.39% | Add +25.8% | 13,724,571 | $73.2M |
| Baker Bros. Advisors LP | 0.27% | No change | 10,123,824 | $54.0M |
| Ra Capital Management, L.P. | 0.30% | New | 6,475,882 | $34.5M |
| Soleus Capital Management, L.P. | 0.62% | New | 3,378,378 | $18.0M |
| Kynam Capital Management, LP | 0.71% | Add +51.6% | 2,415,087 | $12.9M |
| Vanguard Capital Management LLC | 0.00% | Add +63.3% | 2,009,445 | $10.7M |
| BlackRock, Inc. | 0.00% | Add +458.4% | 1,797,501 | $9.6M |
| Sphera Funds Management LTD. | 0.78% | Add +82.7% | 1,019,832 | $5.4M |
| Two Sigma Investments, LP | 0.00% | Add +7.5% | 993,369 | $5.3M |
| ADAR1 Capital Management, LLC | 0.23% | Add +489.5% | 900,900 | $4.8M |
| Millennium Management | 0.00% | Add +120.8% | 844,993 | $4.5M |
| Geode Capital Management, LLC | 0.00% | Add +178.3% | 841,862 | $4.5M |
| Adage Capital Partners Gp, L.L.C. | 0.01% | New | 766,095 | $4.1M |
| Acadian Asset Management LLC | 0.00% | Add +19.5% | 611,359 | $3.3M |
| Morgan Stanley | 0.00% | Add +56.4% | 503,860 | $2.7M |
| State Street Corp. | 0.00% | Add +210.2% | 428,787 | $2.3M |
| UBS Group AG | 0.00% | Add +394.2% | 318,797 | $1.7M |
| Vanguard Fiduciary Trust Co. | 0.00% | Add +81.0% | 284,886 | $1.5M |
| Renaissance Technologies | 0.00% | Add +2.2% | 281,200 | $1.5M |
| Northern Trust Corp. | 0.00% | Add +380.1% | 240,599 | $1.3M |
| Vanguard Portfolio Management LLC | 0.00% | New | 193,920 | $1.0M |
| Marshall Wace, LLP | 0.00% | Reduce -46.9% | 190,692 | $1.0M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | Add +15.2% | 125,606 | $669K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -48.9% | 120,834 | $644K |
| Hillsdale Investment Management Inc. | 0.01% | New | 81,400 | $434K |
| Bank of New York Mellon Corp | 0.00% | New | 68,187 | $363K |
| Charles Schwab Investment Management Inc. | 0.00% | New | 67,622 | $360K |
| Bridgeway Capital Management, LLC | 0.01% | Add +20.6% | 64,500 | $344K |
| Squarepoint Ops LLC | 0.00% | New | 59,540 | $317K |
| Panagora Asset Management Inc. | 0.00% | New | 47,574 | $254K |
| Mariner, LLC | 0.00% | New | 45,261 | $241K |
| Nuveen, LLC | 0.00% | New | 37,023 | $197K |
| Dimensional Fund Advisors LP | 0.00% | No change | 35,210 | $187K |
| Invesco Ltd. | 0.00% | New | 34,742 | $185K |
| Cerity Partners LLC | 0.00% | No change | 32,875 | $175K |
| State of Wyoming | 0.02% | New | 32,862 | $175K |
| Graham Capital Management, L.P. | 0.01% | Add +162.4% | 29,770 | $159K |
| Deutsche Bank AG | 0.00% | New | 27,824 | $148K |
| Wells Fargo & Company | 0.00% | New | 25,325 | $135K |
| Bank of America Corp. | 0.00% | Reduce -57.8% | 23,875 | $127K |
| T. Rowe Price Associates Inc. | 0.00% | New | 22,758 | $122K |
| Citadel Advisors | 0.00% | Reduce -81.9% | 22,554 | $120K |
| Rhumbline Advisers | 0.00% | New | 22,074 | $118K |
| Vanguard Global Advisers, LLC | 0.00% | Add +249.7% | 16,210 | $86K |
| ExodusPoint Capital Management, LP | 0.00% | New | 15,475 | $82K |
| Barclays PLC | 0.00% | Add +68.9% | 14,529 | $77K |
| New York State Common Retirement Fund | 0.00% | New | 14,200 | $76K |
| HSBC Holdings PLC | 0.00% | No change | 13,652 | $74K |
| Mangrove Partners Im, LLC | 0.00% | New | 13,352 | $71K |
| Qube Research & Technologies Ltd | 0.00% | Reduce -20.1% | 13,110 | $70K |
| Citigroup Inc. | 0.00% | Add +260560.0% | 13,033 | $69K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | New | 12,784 | $68K |
| Gsa Capital Partners LLP | 0.00% | New | 12,672 | $68K |
| JPMorgan Chase & Co. | 0.00% | Add +21735.5% | 13,538 | $67K |
| Spark Investment Management LLC | 0.11% | New | 10,600 | $56K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | New | 10,492 | $56K |
| Alliancebernstein L.P. | 0.00% | New | 10,530 | $36K |
| Los Angeles Capital Management LLC | 0.00% | New | 6,430 | $34K |
| FMR LLC | 0.00% | Reduce -6.3% | 5,629 | $30K |
| STRS Ohio | 0.00% | New | 5,500 | $29K |
| BNP Paribas Financial Markets | 0.00% | Add +4220.0% | 4,104 | $22K |
| Group One Trading LLC | 0.00% | No change | 3,907 | $21K |
| Legal & General Group Plc | 0.00% | New | 2,699 | $14K |
| Royal Bank of Canada | 0.00% | Add +14.0% | 2,658 | $14K |
| Ameritas Investment Partners, Inc. | 0.00% | New | 2,520 | $13K |
| Tower Research Capital LLC (TRC) | 0.00% | New | 2,377 | $13K |
| Russell Investments Group, Ltd. | 0.00% | New | 2,220 | $12K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 1,634 | $9K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 1,171 | $6K |
| Quarry LP | 0.00% | New | 755 | $4K |
| Fortitude Family Office, LLC | 0.00% | No change | 230 | $1K |
| Sterling Capital Management LLC | 0.00% | New | 97 | $517 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -99.2% | 22 | $117 |
| Caitong International Asset Management Co., Ltd | 0.00% | New | 18 | $96 |
| Optiver Holding B.V. | 0.00% | Reduce -80.0% | 4 | $21 |
"% of holder's portfolio" is PRLD's weight in each manager's 13F, not the share of Prelude Therapeutics Inc. the manager owns.