First Light Asset Management, LLC

In its 13F for Q1 2024 (holdings as of March 31, 2024, filed May 15, 2024), First Light Asset Management, LLC reported 50 stock positions worth $1.3 billion. Its top holding was Crinetics Pharmaceuticals (CRNX) at 6.1% of the portfolio, followed by Alphatec (ATEC, 5.7%) and Natera (NTRA, 4.6%). Compared with Q4 2023, it opened 12 new positions, sold out of 37, added to 18 and reduced 18. The biggest buy was Natera (NTRA, shares +296%) and the biggest sale an exit from Karuna Therapeutics (KRTX).

Most Recent 13F
Q2 2026
Location
Edina, MN
CIK
0001600004
Portfolio Value
$1.3B (Q1 2024)
SEC Filing
0001999371-24-006153 ↗ filed May 15, 2024

Holdings Value

0$500.0M$1.0B$1.5B$2.0B Q1 2024: $1.3B $1.3B Q1 2024 Q2 2024: $1.1B Q2 2024 Q3 2024: $1.2B Q3 2024 Q4 2024: $1.0B Q4 2024 Q1 2025: $875.7M Q1 2025 Q2 2025: $771.3M Q2 2025 Q3 2025: $1.1B Q3 2025 Q4 2025: $1.3B Q4 2025 Q1 2026: $1.1B Q1 2026 Q2 2026: $1.6B Q2 2026

Holdings 50 stocks · $1.3B

CRNX Crinetics Pharmaceuticals Inc. 6.06% 1,690,177 $79.1M Reduce -15.0%
ATEC Alphatec Holdings Inc. 5.72% 5,418,631 $74.7M Reduce -9.3%
NTRA Natera Inc. 4.60% 656,708 $60.1M Add +295.9%
XENE Xenon Pharmaceuticals Inc. 4.35% 1,320,172 $56.8M Reduce -19.8%
PLRX Pliant Therapeutics Inc. 4.03% 3,534,993 $52.7M Reduce -1.6%
TMDX Transmedics Group Inc. 4.03% 711,682 $52.6M Reduce -5.7%
SWAV Shockwave Medical Inc. 4.03% 161,484 $52.6M Add +35.0%
NEO Neogenomics Inc. 3.97% 3,302,165 $51.9M Reduce -15.9%
IRTC Irhythm Holdings Inc. 3.74% 420,892 $48.8M Add +176.8%
FNA Paragon 28 Inc. 3.60% 3,802,968 $47.0M Reduce -0.4%
TCMD Tactile Systems Technology I 3.29% 2,641,975 $42.9M Reduce -7.6%
ATRC Atricure Inc. 3.22% 1,382,860 $42.1M Add +2.5%
SIBN Si-Bone Inc. 3.10% 2,473,165 $40.5M Reduce -2.9%
RARE Ultragenyx Pharmaceutical Inc. 2.83% 790,446 $36.9M Add +6.2%
CNTA Centessa Pharmaceuticals Ltd. 2.60% 3,002,045 $33.9M New
RCM R1 RCM Inc. 2.52% 2,552,325 $32.9M Add +212.8%
OSCR Oscar Health Inc. Class A 2.39% 2,102,554 $31.3M Add +117.3%
PHLT Performant Healthcare Inc. 2.37% 10,515,127 $30.9M Add +8.7%
INSP Inspire Medical Systems Inc. 2.30% 139,951 $30.1M Add +58.1%
BCYC Bicycle Therapeutics PLC-ADR 2.27% 1,193,051 $29.7M Reduce -23.1%
STVN Stevanato Group SPA 2.05% 835,985 $26.8M Add +14.5%
PODD Insulet Corp. 1.99% 151,264 $25.9M New
MODN Model N Inc. 1.95% 894,241 $25.5M Reduce -42.0%
AVTR Avantor Inc. 1.67% 850,695 $21.8M Add +5728.3%
PRVA Privia Health Group Inc. 1.66% 1,103,601 $21.6M New
ANAB Anaptysbio Inc. 1.63% 944,110 $21.3M Reduce -23.7%
SCTL Societal Cdmo Inc. 1.63% 19,676,396 $21.3M No change
OPRX Optimizerx Corp. 1.62% 1,737,584 $21.1M Add +0.6%
ALPN Alpine Immune Sciences Inc. 1.52% 501,243 $19.9M New
VERA Vera Therapeutics Inc. 1.44% 436,133 $18.8M New
TNDM Tandem Diabetes Care Inc. 1.29% 475,077 $16.8M Add +31.9%
TELA Tela Bio Inc. 1.20% 2,754,028 $15.6M Add +7.8%
IDYA Ideaya Biosciences Inc. 1.13% 335,471 $14.7M Reduce -3.0%
KRMD Koru Medical Systems Inc. 0.94% 5,220,990 $12.3M Add +1.1%
PRTA Prothena Corp. PLC 0.84% 444,953 $11.0M Reduce -59.1%
NARI Inari Medical Inc. 0.79% 213,940 $10.3M New
EVH Evolent Health Inc. Class A 0.72% 288,181 $9.4M Add +252.6%
PEN Penumbra Inc. 0.65% 37,955 $8.5M New
THC Tenet Healthcare Corp. 0.64% 79,523 $8.4M Reduce -59.1%
INSM Insmed Inc. 0.59% 282,766 $7.7M Reduce -56.2%
GPCR Structure Therapeutics Inc. 0.49% 149,113 $6.4M New
AXGN Axogen Inc. 0.47% 765,886 $6.2M Add +177.0%
LIVN Livanova PLC 0.44% 102,792 $5.8M New
HCAT Health Catalyst Inc. 0.42% 734,681 $5.5M Reduce -27.6%
PCVX Vaxcyte Inc. 0.32% 60,284 $4.1M New
GH Guardant Health Inc. 0.30% 189,765 $3.9M Add +31.7%
VTYX Ventyx Biosciences Inc. 0.26% 624,842 $3.4M New
DYN Dyne Therapeutics Inc. 0.23% 105,948 $3.0M New
SLP Simulations Plus Inc. 0.09% 28,741 $1.2M Reduce -16.6%
SONENDO INC 0.04% 5,143,615 $545K No change

Portfolio Sells Q4 2023 → Q1 2024

KRTX Karuna Therapeutics Inc. Sold out 0.00% −7.31
PRTA Prothena Corp. PLC Reduce -59.1% 0.84% −2.34
XENE Xenon Pharmaceuticals Inc. Reduce -19.8% 4.35% −1.75
AXONICS INC Sold out 0.00% −1.60
ATEC Alphatec Holdings Inc. Reduce -9.3% 5.72% −1.54
BMRN Biomarin Pharmaceutical Inc. Sold out 0.00% −1.44
MODN Model N Inc. Reduce -42.0% 1.95% −1.39
BHVN Biohaven Ltd. Sold out 0.00% −1.32
SIBN Si-Bone Inc. Reduce -2.9% 3.10% −1.20
PLRX Pliant Therapeutics Inc. Reduce -1.6% 4.03% −1.20
NEO Neogenomics Inc. Reduce -15.9% 3.97% −1.14
INSM Insmed Inc. Reduce -56.2% 0.59% −1.02
KIDS Orthopediatrics Corp. Sold out 0.00% −0.78
TMDX Transmedics Group Inc. Reduce -5.7% 4.03% −0.76
OLMA Olema Pharmaceuticals Inc. Sold out 0.00% −0.71
THC Tenet Healthcare Corp. Reduce -59.1% 0.64% −0.54
ANAB Anaptysbio Inc. Reduce -23.7% 1.63% −0.50
HALO Halozyme Therapeutics Inc. Sold out 0.00% −0.40
HCAT Health Catalyst Inc. Reduce -27.6% 0.42% −0.33
FNA Paragon 28 Inc. Reduce -0.4% 3.60% −0.22
TECH Bio-Techne Corp. Sold out 0.00% −0.20
IWO iShares Russell 2000 Growth Sold out 0.00% −0.12
EXEL Exelixis Inc. Sold out 0.00% −0.04
ELV Elevance Health Inc. Sold out 0.00% −0.03
NVS Novartis AG-Sponsored ADR Sold out 0.00% −0.03
SLP Simulations Plus Inc. Reduce -16.6% 0.09% −0.03
SNN Smith & Nephew PLC -Spon ADR Sold out 0.00% −0.03
CNC Centene Corp. Sold out 0.00% −0.03
FMS Fresenius Medical Care-ADR Sold out 0.00% −0.03
HUM Humana Inc. Sold out 0.00% −0.03
ENOV Enovis Corp. Sold out 0.00% −0.03
ABBV Abbvie Inc. Sold out 0.00% −0.03
SNY Sanofi-ADR Sold out 0.00% −0.03
GSK GSK PLC-Spon ADR Sold out 0.00% −0.03
GILD Gilead Sciences Inc. Sold out 0.00% −0.03
TAK Takeda Pharmaceutic-SP ADR Sold out 0.00% −0.03
VTRS Viatris Inc. Sold out 0.00% −0.03
MDT Medtronic PLC Sold out 0.00% −0.03
JNJ Johnson & Johnson Sold out 0.00% −0.03
IART Integra Lifesciences Holding Sold out 0.00% −0.03
HCA HCA Healthcare Inc. Sold out 0.00% −0.03
QDEL Quidelortho Corp. Sold out 0.00% −0.03
QGEN Qiagen NV Sold out 0.00% −0.02
UTHR United Therapeutics Corp. Sold out 0.00% −0.02
XRAY Dentsply Sirona Inc. Sold out 0.00% −0.02
BIIB Biogen Inc. Sold out 0.00% −0.02
LH Laboratory CRP of Amer Hldgs Sold out 0.00% −0.02
PDCO Patterson Cos Inc. Sold out 0.00% −0.02
RVTY Revvity Inc. Sold out 0.00% −0.02
BAYRY Bayer AG-Sponsored ADR Sold out 0.00% −0.02

Portfolio Buys Q4 2023 → Q1 2024

NTRA Natera Inc. Add +295.9% 4.60% +3.76
CNTA Centessa Pharmaceuticals Ltd. New 2.60% +2.60
IRTC Irhythm Holdings Inc. Add +176.8% 3.74% +2.43
SWAV Shockwave Medical Inc. Add +35.0% 4.03% +2.19
PODD Insulet Corp. New 1.99% +1.99
RCM R1 RCM Inc. Add +212.8% 2.52% +1.82
OSCR Oscar Health Inc. Class A Add +117.3% 2.39% +1.68
PRVA Privia Health Group Inc. New 1.66% +1.66
AVTR Avantor Inc. Add +5728.3% 1.67% +1.64
ALPN Alpine Immune Sciences Inc. New 1.52% +1.52
VERA Vera Therapeutics Inc. New 1.44% +1.44
INSP Inspire Medical Systems Inc. Add +58.1% 2.30% +0.85
NARI Inari Medical Inc. New 0.79% +0.79
PEN Penumbra Inc. New 0.65% +0.65
EVH Evolent Health Inc. Class A Add +252.6% 0.72% +0.51
GPCR Structure Therapeutics Inc. New 0.49% +0.49
STVN Stevanato Group SPA Add +14.5% 2.05% +0.45
LIVN Livanova PLC New 0.44% +0.44
TNDM Tandem Diabetes Care Inc. Add +31.9% 1.29% +0.43
AXGN Axogen Inc. Add +177.0% 0.47% +0.32
PCVX Vaxcyte Inc. New 0.32% +0.32
VTYX Ventyx Biosciences Inc. New 0.26% +0.26
DYN Dyne Therapeutics Inc. New 0.23% +0.23
GH Guardant Health Inc. Add +31.7% 0.30% −0.01
RARE Ultragenyx Pharmaceutical Inc. Add +6.2% 2.83% −0.04
PHLT Performant Healthcare Inc. Add +8.7% 2.37% −0.06
KRMD Koru Medical Systems Inc. Add +1.1% 0.94% −0.08
TELA Tela Bio Inc. Add +7.8% 1.20% −0.17
OPRX Optimizerx Corp. Add +0.6% 1.62% −0.37
ATRC Atricure Inc. Add +2.5% 3.22% −0.65

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 31$1.6BNEO, SIBN, AXGN, APGE, PVLA
Q1 2026 35$1.1BAXGN, PVLA, NEO, SIBN, CNTA
Q4 2025 33$1.3BAXGN, NEO, SIBN, PVLA, CNTA
Q3 2025 41$1.1BAXGN, PHLT, CNTA, NEO, AMLX
Q2 2025 38$771.3MANAB, CNTA, PHLT, NEO, AXGN
Q1 2025 37$875.7MANAB, AXGN, CNTA, NEO, TWST
Q4 2024 36$1.0BFNA, CNTA, AXGN, ATRC, TWST
Q3 2024 38$1.2BCNTA, FNA, EVH, AXGN, ATRC
Q2 2024 44$1.1BFNA, ATEC, CRNX, NEO, XENE
Q1 2024 50$1.3BCRNX, ATEC, NTRA, XENE, PLRX