Xenon PharmaceuticalsXENE
13F holders, Q2 2026 (June 30)315holders +25
46new positions
22sold out
9famous investors
$60.32avg. 13F price*
At the end of Q2 2026, 315 institutions reported holding Xenon Pharmaceuticals Inc. (XENE) in their 13F filings, up 25 from Q1 2026. 46 opened new positions and 22 sold out. The largest holders were FMR LLC ($582.4M), BlackRock, Inc. ($454.1M) and Avoro Capital Advisors LLC ($348.7M). 9 famous investors held it, including Stanley Druckenmiller (0.3% of Duquesne Family Office's portfolio), Paul Tudor Jones (0.1% of Tudor Investment Corporation's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Xenon Pharmaceuticals Inc.
- CUSIP
- 98420N105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 46 | $169.7M |
| Exits | 22 | $209.6M |
All 13F filers, Q1 2026 → Q2 2026: 16,005,203 shares bought and 15,127,913 shares sold, net +877,290 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 315 holders
| FMR LLC | 0.03% | Reduce -10.8% | 9,647,998 | $582.4M |
| BlackRock, Inc. | 0.01% | Add +33.4% | 7,522,482 | $454.1M |
| Avoro Capital Advisors LLC | 3.13% | No change | 5,777,777 | $348.7M |
| Polar Capital Holdings Plc | 0.78% | Add +3.8% | 4,570,556 | $275.9M |
| Driehaus Capital Management LLC | 1.55% | Reduce -1.6% | 4,418,557 | $266.7M |
| Jupiter Topco LLC | 0.10% | — | 4,186,519 | $252.7M |
| T. Rowe Price Associates Inc. | 0.02% | Add +144.3% | 3,248,219 | $196.1M |
| JPMorgan Chase & Co. | 0.01% | Add +36.1% | 2,617,360 | $157.4M |
| Capital International Investors | 0.03% | Reduce -11.7% | 2,361,639 | $142.5M |
| T. Rowe Price Investment Management, Inc. | 0.09% | Add +127.8% | 2,168,581 | $130.9M |
| State Street Corp. | 0.00% | Add +14.5% | 1,969,629 | $118.9M |
| Two Sigma Investments, LP | 0.08% | Add +171.1% | 1,642,848 | $99.2M |
| Deerfield Management Company, L.P. | 1.21% | No change | 1,615,696 | $97.5M |
| Affinity Asset Advisors, LLC | 4.79% | Reduce -4.8% | 1,595,000 | $96.3M |
| Westfield Capital Management Co. LP | 0.30% | Add +7.5% | 1,507,294 | $91.0M |
| Alliancebernstein L.P. | 0.03% | Add +11.3% | 1,562,276 | $90.8M |
| Franklin Resources Inc. | 0.02% | Add +12.3% | 1,437,712 | $86.8M |
| Wellington Management Group LLP | 0.01% | Reduce -70.5% | 1,425,492 | $86.0M |
| Citadel Advisors | 0.05% | Reduce -47.2% | 1,401,242 | $84.6M |
| Geode Capital Management, LLC | 0.00% | Add +25.4% | 1,370,114 | $82.7M |
| Siren, L.L.C. | 1.62% | No change | 1,318,564 | $79.6M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.08% | Reduce -3.8% | 1,290,731 | $77.9M |
| Pictet Asset Management Holding SA | 0.07% | Add +74.7% | 1,187,723 | $71.6M |
| Braidwell LP | 2.62% | Reduce -15.5% | 1,131,452 | $68.3M |
| Nuveen, LLC | 0.01% | Add +297.2% | 993,126 | $59.9M |
| Invesco Ltd. | 0.00% | Add +1428.6% | 903,458 | $54.5M |
| Orbimed Advisors LLC | 1.02% | Reduce -15.8% | 892,471 | $53.9M |
| Caligan Partners LP | 2.59% | Reduce -36.1% | 889,944 | $53.7M |
| American Century Companies Inc. | 0.02% | Add +30.2% | 884,319 | $53.4M |
| Federated Hermes, Inc. | 0.08% | Reduce -9.1% | 883,737 | $53.3M |
| Capital World Investors | 0.01% | Add +2.7% | 862,775 | $52.1M |
| Goldman Sachs Group Inc. | 0.00% | Add +0.5% | 773,625 | $46.7M |
| Vanguard Portfolio Management LLC | 0.00% | Add +38.0% | 749,651 | $45.2M |
| Vestal Point Capital, LP | 0.99% | Add +9.4% | 700,000 | $42.3M |
| Alyeska Investment Group, L.P. | 0.11% | Reduce -46.3% | 697,692 | $42.1M |
| Marshall Wace, LLP | 0.04% | New | 689,342 | $41.6M |
| Rock Springs Capital Management LP | 2.01% | Reduce -10.4% | 683,907 | $41.3M |
| Northern Trust Corp. | 0.00% | Add +27.2% | 671,566 | $40.5M |
| Panagora Asset Management Inc. | 0.12% | New | 664,031 | $40.1M |
| First Turn Management, LLC | 3.88% | Reduce -23.7% | 600,200 | $36.2M |
| Tudor Investment Corporation | 0.14% | Add +10.1% | 545,387 | $32.9M |
| Loomis Sayles & Co. L P | 0.04% | Reduce -6.7% | 527,273 | $31.8M |
| Octagon Capital Advisors LP | 2.71% | No change | 490,000 | $29.6M |
| Novo Holdings A/S | 1.70% | No change | 485,438 | $29.3M |
| Candriam S.C.A. | 0.13% | Reduce -2.9% | 462,768 | $27.9M |
| TimesSquare Capital Management, LLC | 0.40% | Add +25.7% | 451,593 | $27.3M |
| Logos Global Management LP | 1.17% | No change | 450,000 | $27.2M |
| Trails Edge Capital Partners, LP | 4.22% | No change | 440,000 | $26.6M |
| Bank of New York Mellon Corp | 0.00% | Add +6.4% | 421,518 | $25.4M |
| Algert Global LLC | 0.30% | Add +58.9% | 419,773 | $25.3M |
| Aberdeen Group plc | 0.03% | Reduce -33.0% | 408,736 | $24.7M |
| Morgan Stanley | 0.00% | Reduce -14.3% | 406,257 | $24.5M |
| Fiera Capital Corp | 0.09% | Reduce -42.8% | 405,638 | $24.5M |
| Bank of America Corp. | 0.00% | Add +52.3% | 404,067 | $24.4M |
| Parkman Healthcare Partners LLC | 2.46% | Reduce -20.1% | 397,379 | $24.0M |
| Nicholas Investment Partners, LP | 1.54% | Add +60.2% | 395,844 | $23.9M |
| Millennium Management | 0.02% | Add +86.7% | 376,777 | $22.7M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -0.1% | 374,748 | $22.6M |
| Baker Bros. Advisors LP | 0.11% | No change | 370,208 | $22.3M |
| Jones Hill Capital LP | 4.72% | New | 367,900 | $22.2M |
| Ameriprise Financial Inc. | 0.00% | Add +303.7% | 318,548 | $19.2M |
| Man Group plc | 0.03% | New | 310,617 | $18.7M |
| Adage Capital Partners Gp, L.L.C. | 0.03% | Reduce -36.2% | 300,000 | $18.1M |
| Soleus Capital Management, L.P. | 0.56% | Reduce -8.6% | 267,000 | $16.1M |
| Jump Financial, LLC | 0.15% | Add +67.4% | 260,730 | $15.7M |
| DAFNA Capital Management LLC | 2.89% | No change | 250,772 | $15.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +31.9% | 249,473 | $15.1M |
| State of Wisconsin Investment Board | 0.03% | Reduce -2.2% | 248,821 | $15.0M |
| Nan Fung Trinity (hk) Ltd. | 1.48% | No change | 247,765 | $15.0M |
| Duquesne Family Office | 0.33% | No change | 238,600 | $14.4M |
| Allspring Global Investments Holdings, LLC | 0.02% | Reduce -4.8% | 234,412 | $14.1M |
| Redmile Group, LLC | 0.93% | Reduce -12.7% | 229,374 | $13.8M |
| Schonfeld Strategic Advisors LLC | 0.07% | Reduce -30.0% | 227,330 | $13.7M |
| D. E. Shaw & Co. | 0.01% | Add +1082.3% | 223,922 | $13.5M |
| Patient Square Capital LP | 2.06% | Reduce -3.1% | 220,000 | $13.3M |
| New York State Common Retirement Fund | 0.02% | Add +11.7% | 210,471 | $12.7M |
| Jennison Associates LLC | 0.01% | Reduce -84.2% | 208,060 | $12.6M |
| Neuberger Berman Group LLC | 0.01% | Add +58.4% | 206,604 | $12.5M |
| Trexquant Investment LP | 0.08% | Add +200.6% | 202,455 | $12.2M |
| DNB Asset Management AS | 0.03% | Add +10.7% | 200,451 | $12.1M |
| Integral Health Asset Management, LLC | 0.50% | No change | 200,000 | $12.1M |
| Eversept Partners, LP | 0.65% | Add +51.7% | 196,532 | $11.9M |
| Balyasny Asset Management L.P. | 0.02% | Reduce -17.3% | 193,407 | $11.7M |
| Deutsche Bank AG | 0.00% | Add +17.5% | 191,126 | $11.5M |
| Renaissance Technologies | 0.02% | Reduce -37.7% | 187,110 | $11.3M |
| Silverarc Capital Management, LLC | 1.25% | Reduce -5.5% | 186,821 | $11.3M |
| Boothbay Fund Management, LLC | 0.22% | Reduce -32.2% | 183,343 | $11.1M |
| NEXTBio Capital Management LP | 5.09% | No change | 183,225 | $11.1M |
| Wells Fargo & Company | 0.00% | Add +50.4% | 173,945 | $10.5M |
| ADAR1 Capital Management, LLC | 0.48% | Reduce -27.2% | 166,550 | $10.1M |
| Peregrine Capital Management LLC | 0.32% | Add +15.2% | 164,894 | $10.0M |
| Swiss National Bank | 0.01% | Add +3.2% | 162,700 | $9.8M |
| Foresite Capital Management IV, LLC | 3.33% | No change | 160,000 | $9.7M |
| Woodline Partners LP | 0.03% | Add +3.3% | 155,302 | $9.4M |
| Russell Investments Group, Ltd. | 0.01% | Add +18.4% | 153,227 | $9.2M |
| HSBC Holdings PLC | 0.00% | Add +24.6% | 151,474 | $9.1M |
| Susquehanna Portfolio Strategies, LLC | 0.13% | Add +620.5% | 133,059 | $8.0M |
| Point72 Asset Management | 0.01% | New | 130,378 | $7.9M |
| Granahan Investment Management, LLC | 0.28% | Add +23.9% | 129,443 | $7.8M |
| KBC Group NV | 0.02% | No change | 129,010 | $7.8M |
"% of holder's portfolio" is XENE's weight in each manager's 13F, not the share of Xenon Pharmaceuticals Inc. the manager owns.