First Light Asset Management, LLC

In its 13F for Q3 2024 (holdings as of September 30, 2024, filed November 14, 2024), First Light Asset Management, LLC reported 38 stock positions worth $1.2 billion. Its top holding was Centessa Pharmaceuticals (CNTA) at 7.9% of the portfolio, followed by Paragon 28 (FNA, 5.6%) and Evolent Health Class A (EVH, 5.4%). Compared with Q2 2024, it opened 5 new positions, sold out of 11, added to 14 and reduced 19. The biggest buy was Centessa Pharmaceuticals (CNTA, shares +24%) and the biggest sale Alphatec (ATEC, shares −97%).

Most Recent 13F
Q2 2026
Location
Edina, MN
CIK
0001600004
Portfolio Value
$1.2B (Q3 2024)
SEC Filing
0001839882-24-039271 ↗ filed Nov 14, 2024

Holdings Value

0$500.0M$1.0B$1.5B$2.0B Q1 2024: $1.3B Q1 2024 Q2 2024: $1.1B Q2 2024 Q3 2024: $1.2B $1.2B Q3 2024 Q4 2024: $1.0B Q4 2024 Q1 2025: $875.7M Q1 2025 Q2 2025: $771.3M Q2 2025 Q3 2025: $1.1B Q3 2025 Q4 2025: $1.3B Q4 2025 Q1 2026: $1.1B Q1 2026 Q2 2026: $1.6B Q2 2026

Holdings 38 stocks · $1.2B

CNTA Centessa Pharmaceuticals Ltd. 7.90% 5,940,132 $95.0M Add +24.3%
FNA Paragon 28 Inc. 5.64% 10,154,643 $67.8M Add +24.2%
EVH Evolent Health Inc. Class A 5.41% 2,298,261 $65.0M Add +59.0%
AXGN Axogen Inc. 4.77% 4,090,296 $57.3M Add +22.3%
ATRC Atricure Inc. 4.35% 1,865,536 $52.3M Reduce -5.0%
INSM Insmed Inc. 4.18% 688,910 $50.3M Add +25.0%
CRNX Crinetics Pharmaceuticals Inc. 4.01% 943,611 $48.2M Reduce -21.4%
XENE Xenon Pharmaceuticals Inc. 3.87% 1,181,662 $46.5M Reduce -9.5%
NEO Neogenomics Inc. 3.78% 3,076,555 $45.4M Reduce -18.7%
DYN Dyne Therapeutics Inc. 3.76% 1,257,285 $45.2M Add +228.8%
TNDM Tandem Diabetes Care Inc. 3.62% 1,025,307 $43.5M Add +44.7%
RARE Ultragenyx Pharmaceutical Inc. 3.49% 755,102 $41.9M Reduce -21.6%
PHLT Performant Healthcare Inc. 3.49% 11,210,400 $41.9M Add +6.6%
TMDX Transmedics Group Inc. 3.47% 265,734 $41.7M Reduce -11.6%
OSCR Oscar Health Inc. Class A 3.12% 1,765,892 $37.5M Reduce -5.4%
PODD Insulet Corp. 3.08% 159,082 $37.0M Reduce -26.2%
HCAT Health Catalyst Inc. 2.91% 4,296,490 $35.0M Add +8.6%
ANAB Anaptysbio Inc. 2.64% 948,131 $31.8M Add +21.7%
CDMO Avid Bioservices Inc. 2.62% 2,771,853 $31.5M New
VERA Vera Therapeutics Inc. 2.59% 705,234 $31.2M Reduce -29.9%
PLRX Pliant Therapeutics Inc. 2.40% 2,575,546 $28.9M Reduce -24.3%
RGEN Repligen Corp. 2.05% 165,873 $24.7M New
NTRA Natera Inc. 1.95% 184,939 $23.5M Reduce -49.9%
GPCR Structure Therapeutics Inc. 1.85% 506,222 $22.2M Reduce -14.3%
BCYC Bicycle Therapeutics PLC-ADR 1.82% 967,006 $21.9M Reduce -30.2%
SIBN Si-Bone Inc. 1.78% 1,526,215 $21.3M Reduce -38.3%
KYMR Kymera Therapeutics Inc. 1.60% 406,348 $19.2M New
KRMD Koru Medical Systems Inc. 1.27% 5,598,925 $15.3M Add +11.1%
GH Guardant Health Inc. 1.24% 648,993 $14.9M Add +55.6%
OPRX Optimizerx Corp. 1.16% 1,811,611 $14.0M Reduce -0.8%
RLAY Relay Therapeutics Inc. 0.91% 1,542,406 $10.9M New
AVTR Avantor Inc. 0.77% 359,150 $9.3M Reduce -39.8%
MOH Molina Healthcare Inc. 0.76% 26,528 $9.1M New
ASND Ascendis Pharma A/S 0.64% 51,723 $7.7M Add +43.0%
NARI Inari Medical Inc. 0.60% 174,590 $7.2M Reduce -63.0%
EXAS Exact Sciences Corp. 0.39% 69,447 $4.7M Reduce -44.6%
ATEC Alphatec Holdings Inc. 0.06% 138,006 $767K Reduce -97.4%
SONENDO INC 0.02% 5,886,207 $254K Add +14.4%

Portfolio Sells Q2 2024 → Q3 2024

ATEC Alphatec Holdings Inc. Reduce -97.4% 0.06% −4.82
LIVN Livanova PLC Sold out 0.00% −3.41
RCM R1 RCM Inc. Sold out 0.00% −2.71
NTRA Natera Inc. Reduce -49.9% 1.95% −1.55
TCMD Tactile Systems Technology I Sold out 0.00% −1.40
NARI Inari Medical Inc. Reduce -63.0% 0.60% −1.39
SIBN Si-Bone Inc. Reduce -38.3% 1.78% −1.03
PCVX Vaxcyte Inc. Sold out 0.00% −0.92
NEO Neogenomics Inc. Reduce -18.7% 3.78% −0.82
PLRX Pliant Therapeutics Inc. Reduce -24.3% 2.40% −0.80
PODD Insulet Corp. Reduce -26.2% 3.08% −0.73
SVRA Savara Inc. Sold out 0.00% −0.71
CRNX Crinetics Pharmaceuticals Inc. Reduce -21.4% 4.01% −0.70
PEN Penumbra Inc. Sold out 0.00% −0.68
BCYC Bicycle Therapeutics PLC-ADR Reduce -30.2% 1.82% −0.64
VERA Vera Therapeutics Inc. Reduce -29.9% 2.59% −0.60
XENE Xenon Pharmaceuticals Inc. Reduce -9.5% 3.87% −0.59
HUM Humana Inc. Sold out 0.00% −0.53
CNC Centene Corp. Sold out 0.00% −0.52
TMDX Transmedics Group Inc. Reduce -11.6% 3.47% −0.50
STVN Stevanato Group SPA Sold out 0.00% −0.44
OPRX Optimizerx Corp. Reduce -0.8% 1.16% −0.44
AVTR Avantor Inc. Reduce -39.8% 0.77% −0.33
INSP Inspire Medical Systems Inc. Sold out 0.00% −0.33
GPCR Structure Therapeutics Inc. Reduce -14.3% 1.85% −0.18
SLP Simulations Plus Inc. Sold out 0.00% −0.12
EXAS Exact Sciences Corp. Reduce -44.6% 0.39% −0.07
RARE Ultragenyx Pharmaceutical Inc. Reduce -21.6% 3.49% +0.02
ATRC Atricure Inc. Reduce -5.0% 4.35% +0.43
OSCR Oscar Health Inc. Class A Reduce -5.4% 3.12% +0.53

Portfolio Buys Q2 2024 → Q3 2024

CNTA Centessa Pharmaceuticals Ltd. Add +24.3% 7.90% +4.12
EVH Evolent Health Inc. Class A Add +59.0% 5.41% +2.98
AXGN Axogen Inc. Add +22.3% 4.77% +2.65
CDMO Avid Bioservices Inc. New 2.62% +2.62
DYN Dyne Therapeutics Inc. Add +228.8% 3.76% +2.57
RGEN Repligen Corp. New 2.05% +2.05
KYMR Kymera Therapeutics Inc. New 1.60% +1.60
TNDM Tandem Diabetes Care Inc. Add +44.7% 3.62% +1.12
INSM Insmed Inc. Add +25.0% 4.18% +0.95
ANAB Anaptysbio Inc. Add +21.7% 2.64% +0.93
RLAY Relay Therapeutics Inc. New 0.91% +0.91
PHLT Performant Healthcare Inc. Add +6.6% 3.49% +0.82
MOH Molina Healthcare Inc. New 0.76% +0.76
FNA Paragon 28 Inc. Add +24.2% 5.64% +0.74
HCAT Health Catalyst Inc. Add +8.6% 2.91% +0.69
ASND Ascendis Pharma A/S Add +43.0% 0.64% +0.21
GH Guardant Health Inc. Add +55.6% 1.24% +0.18
KRMD Koru Medical Systems Inc. Add +11.1% 1.27% +0.10
SONENDO INC Add +14.4% 0.02% −0.01

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 31$1.6BNEO, SIBN, AXGN, APGE, PVLA
Q1 2026 35$1.1BAXGN, PVLA, NEO, SIBN, CNTA
Q4 2025 33$1.3BAXGN, NEO, SIBN, PVLA, CNTA
Q3 2025 41$1.1BAXGN, PHLT, CNTA, NEO, AMLX
Q2 2025 38$771.3MANAB, CNTA, PHLT, NEO, AXGN
Q1 2025 37$875.7MANAB, AXGN, CNTA, NEO, TWST
Q4 2024 36$1.0BFNA, CNTA, AXGN, ATRC, TWST
Q3 2024 38$1.2BCNTA, FNA, EVH, AXGN, ATRC
Q2 2024 44$1.1BFNA, ATEC, CRNX, NEO, XENE
Q1 2024 50$1.3BCRNX, ATEC, NTRA, XENE, PLRX