Kalehua Capital Management LLC
In its 13F for Q1 2026 (holdings as of March 31, 2026, filed May 15, 2026), Kalehua Capital Management LLC reported 25 stock positions worth $141.3 million. Its top holding was Alpha Architect 1-3 MNTH Box (BOXX) at 18.0% of the portfolio, followed by X4 Pharmaceuticals (XFOR, 10.9%) and Surrozen (SRZN, 7.9%). Compared with Q4 2025, it opened 9 new positions, sold out of 3, added to 1 and reduced 3. The biggest buy was a new position in Veradermics (MANE) and the biggest sale Alpha Architect 1-3 MNTH Box (BOXX, shares −5%).
- Most Recent 13F
- Q2 2026
- Location
- DALLAS, TX
- CIK
- 0002106181
- Portfolio Value
- $141.3M (Q1 2026)
- SEC Filing
- 0002106181-26-000005 ↗ filed May 15, 2026
Holdings Value
Holdings 25 stocks · $141.3M
| BOXX Alpha Architect 1-3 MNTH Box | 17.96% | 218,278 | $25.4M | Reduce -5.4% |
| XFOR X4 Pharmaceuticals Inc. | 10.88% | 3,722,840 | $15.4M | No change |
| SRZN Surrozen Inc. | 7.94% | 385,178 | $11.2M | No change |
| MANE Veradermics Inc. | 6.51% | 145,695 | $9.2M | New |
| RLAY Relay Therapeutics Inc. | 6.35% | 901,457 | $9.0M | No change |
| SION Sionna Therapeutics Inc. | 5.59% | 197,072 | $7.9M | No change |
| ACRS Aclaris Therapeutics Inc. | 4.86% | 1,832,365 | $6.9M | New |
| IKT Inhibikase Therapeutics Inc. | 4.54% | 3,821,890 | $6.4M | Add +118.4% |
| ORKA Oruka Therapeutics Inc. | 4.11% | 118,524 | $5.8M | No change |
| PHVS Pharvaris NV | 3.97% | 198,772 | $5.6M | No change |
| QURE Uniqure NV | 3.37% | 291,109 | $4.8M | New |
| SEPN Septerna Inc. | 3.31% | 194,544 | $4.7M | No change |
| CMPS Compass Pathways PLC | 3.21% | 819,692 | $4.5M | No change |
| LONA Leonabio Inc. | 2.86% | 393,701 | $4.0M | No change |
| DMRA Damora Therapeutics Inc. | 2.55% | 139,000 | $3.6M | New |
| GOSS Gossamer Bio Inc. | 2.38% | 10,236,293 | $3.4M | New |
| MLTX Moonlake Immunotherapeutics | 2.32% | 175,734 | $3.3M | No change |
| TYRA Tyra Biosciences Inc. | 2.02% | 74,465 | $2.9M | No change |
| PEPG Pepgen Inc. | 1.25% | 1,000,000 | $1.8M | New |
| TIL Instil Bio Inc. | 1.07% | 183,030 | $1.5M | New |
| TNYA Tenaya Therapeutics Inc. | 0.98% | 2,000,000 | $1.4M | No change |
| KRRO Korro Bio Inc. | 0.88% | 109,376 | $1.2M | New |
| KLRS Kalaris Therapeutics Inc. | 0.55% | 135,585 | $782K | Reduce -3.1% |
| DMAC Diamedica Therapeutics Inc. | 0.30% | 62,488 | $423K | Reduce -34.5% |
| LOOP Loop Industries Inc. | 0.26% | 347,539 | $361K | New |
Portfolio Sells Q4 2025 → Q1 2026
| BOXX Alpha Architect 1-3 MNTH Box | Reduce -5.4% | 17.96% | −8.32 |
| ALLO Allogene Therapeutics Inc. | Sold out | 0.00% | −3.45 |
| ORIC Oric Pharmaceuticals Inc. | Sold out | 0.00% | −2.16 |
| VRCA Verrica Pharmaceuticals Inc. | Sold out | 0.00% | −1.94 |
| KLRS Kalaris Therapeutics Inc. | Reduce -3.1% | 0.55% | −0.61 |
| DMAC Diamedica Therapeutics Inc. | Reduce -34.5% | 0.30% | −0.45 |
Portfolio Buys Q4 2025 → Q1 2026
| MANE Veradermics Inc. | New | 6.51% | +6.51 |
| ACRS Aclaris Therapeutics Inc. | New | 4.86% | +4.86 |
| QURE Uniqure NV | New | 3.37% | +3.37 |
| DMRA Damora Therapeutics Inc. | New | 2.55% | +2.55 |
| GOSS Gossamer Bio Inc. | New | 2.38% | +2.38 |
| PEPG Pepgen Inc. | New | 1.25% | +1.25 |
| TIL Instil Bio Inc. | New | 1.07% | +1.07 |
| IKT Inhibikase Therapeutics Inc. | Add +118.4% | 4.54% | +0.99 |
| KRRO Korro Bio Inc. | New | 0.88% | +0.88 |
| LOOP Loop Industries Inc. | New | 0.26% | +0.26 |