Kynam Capital Management, LP

In its 13F for Q3 2024 (holdings as of September 30, 2024, filed November 14, 2024), Kynam Capital Management, LP reported 24 stock positions worth $1.3 billion. Its top holding was Natera (NTRA) at 20.1% of the portfolio, followed by Vaxcyte (PCVX, 9.2%) and Celldex Therapeutics (CLDX, 9.1%). Compared with Q2 2024, it opened 2 new positions, added to 17 and reduced 4. The biggest buy was CG Oncology (CGON, shares +3185%) and the biggest sale Protagonist Therapeutics (PTGX, shares −43%).

Most Recent 13F
Q2 2026
Location
PRINCETON, NJ
CIK
0001907884
Portfolio Value
$1.3B (Q3 2024)
SEC Filing
0001085146-24-005812 ↗ filed Nov 14, 2024

Holdings Value

0$500.0M$1.0B$1.5B$2.0B Q1 2024: $898.9M Q1 2024 Q2 2024: $955.2M Q2 2024 Q3 2024: $1.3B $1.3B Q3 2024 Q4 2024: $1.5B Q4 2024 Q1 2025: $1.2B Q1 2025 Q2 2025: $928.8M Q2 2025 Q3 2025: $1.3B Q3 2025 Q4 2025: $1.5B Q4 2025 Q1 2026: $1.6B Q1 2026 Q2 2026: $1.8B Q2 2026

Holdings 24 stocks · $1.3B

NTRA Natera Inc. 20.09% 2,042,471 $259.3M Add +1.4%
PCVX Vaxcyte Inc. 9.20% 1,039,288 $118.8M Add +38.0%
CLDX Celldex Therapeutics Inc. 9.11% 3,458,609 $117.6M Add +2.0%
SNDX Syndax Pharmaceuticals Inc. 8.72% 5,842,925 $112.5M Add +2.1%
COGT Cogent Biosciences Inc. 7.73% 9,239,731 $99.8M Reduce -0.2%
DVAX Dynavax Technologies Corp. 7.19% 8,332,687 $92.8M Add +17.6%
VERA Vera Therapeutics Inc. 5.40% 1,576,549 $69.7M Add +2.1%
BCRX Biocryst Pharmaceuticals Inc. 5.35% 9,085,368 $69.0M Add +2.9%
CGON CG Oncology Inc. 5.18% 1,770,805 $66.8M Add +3184.7%
VRDN Viridian Therapeutics Inc. 4.43% 2,511,295 $57.1M Add +43.5%
WVE Wave Life Sciences Ltd. 3.11% 4,899,497 $40.2M Add +23.2%
BEAM Beam Therapeutics Inc. 2.47% 1,302,085 $31.9M New
TSVT 2SEVENTY Bio Inc. 2.18% 5,953,825 $28.1M No change
LQDA Liquidia Corp. 1.76% 2,266,328 $22.7M Add +147.3%
PTGX Protagonist Therapeutics Inc. 1.59% 456,369 $20.5M Reduce -43.0%
TVTX Travere Therapeutics Inc. 1.49% 1,371,511 $19.2M Reduce -32.2%
IRWD Ironwood Pharmaceuticals Inc. 1.18% 3,685,563 $15.2M Add +124.5%
ENGN Engene Holdings Inc. 0.89% 1,736,227 $11.5M New
TYRA Tyra Biosciences Inc. 0.85% 467,947 $11.0M Reduce -17.4%
AMARIN CORP PLC 0.60% 12,414,628 $7.8M Add +2.1%
STRO Sutro Biopharma Inc. Com SHS 0.55% 2,066,447 $7.1M Add +2.1%
CRBU Caribou Biosciences Inc. 0.36% 2,356,147 $4.6M Add +43.1%
SLRN Acelyrin Inc. 0.32% 847,366 $4.2M Add +1.9%
BNR Burning Rock Biotech Ltd.-ADR 0.25% 989,217 $3.2M Add +1.5%

Options reported separately and not counted above: VRTX puts ($14.0M).

Portfolio Sells Q2 2024 → Q3 2024

PTGX Protagonist Therapeutics Inc. Reduce -43.0% 1.59% −1.31
COGT Cogent Biosciences Inc. Reduce -0.2% 7.73% −0.44
TVTX Travere Therapeutics Inc. Reduce -32.2% 1.49% −0.25
TYRA Tyra Biosciences Inc. Reduce -17.4% 0.85% −0.10

Portfolio Buys Q2 2024 → Q3 2024

CGON CG Oncology Inc. Add +3184.7% 5.18% +5.00
PCVX Vaxcyte Inc. Add +38.0% 9.20% +3.25
BEAM Beam Therapeutics Inc. New 2.47% +2.47
VRDN Viridian Therapeutics Inc. Add +43.5% 4.43% +2.04
WVE Wave Life Sciences Ltd. Add +23.2% 3.11% +1.04
ENGN Engene Holdings Inc. New 0.89% +0.89
LQDA Liquidia Corp. Add +147.3% 1.76% +0.60
CRBU Caribou Biosciences Inc. Add +43.1% 0.36% +0.08
IRWD Ironwood Pharmaceuticals Inc. Add +124.5% 1.18% +0.06
SLRN Acelyrin Inc. Add +1.9% 0.32% −0.06
STRO Sutro Biopharma Inc. Com SHS Add +2.1% 0.55% −0.07
AMARIN CORP PLC Add +2.1% 0.60% −0.27
BCRX Biocryst Pharmaceuticals Inc. Add +2.9% 5.35% −0.36
BNR Burning Rock Biotech Ltd.-ADR Add +1.5% 0.25% −0.41
VERA Vera Therapeutics Inc. Add +2.1% 5.40% −0.45
DVAX Dynavax Technologies Corp. Add +17.6% 7.19% −1.13
NTRA Natera Inc. Add +1.4% 20.09% −2.75
SNDX Syndax Pharmaceuticals Inc. Add +2.1% 8.72% −3.58
CLDX Celldex Therapeutics Inc. Add +2.0% 9.11% −4.02

Options Activity Q2 2024 → Q3 2024

SPY SS SPDR S&P 500 ETF Trust-US put Sold out 200,000 $109.1Mbefore exit
INSM Insmed Inc. call Sold out 1,000,000 $67.0Mbefore exit
VRTX Vertex Pharmaceuticals Inc. put Reduce -90.9% 30,000 $14.0M
ALNY Alnylam Pharmaceuticals Inc. put Sold out 43,000 $10.4Mbefore exit

Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 32$1.8BCLDX, SNDX, PCVX, COGT, VERA
Q1 2026 36$1.6BSNDX, CLDX, PCVX, COGT, VERA
Q4 2025 35$1.5BCOGT, VERA, SNDX, CLDX, PCVX
Q3 2025 35$1.3BCLDX, SNDX, VERA, COGT, PCVX
Q2 2025 31$928.8MCLDX, PCVX, VERA, SNDX, BCRX
Q1 2025 31$1.2BNTRA, PCVX, CLDX, SNDX, BCRX
Q4 2024 29$1.5BNTRA, PCVX, CLDX, SNDX, DVAX
Q3 2024 24$1.3BNTRA, PCVX, CLDX, SNDX, COGT
Q2 2024 22$955.2MNTRA, CLDX, SNDX, DVAX, COGT
Q1 2024 21$898.9MNTRA, SNDX, CLDX, VERA, COGT