Novo Holdings A/S

In its 13F for Q4 2024 (holdings as of December 31, 2024, filed February 14, 2025), Novo Holdings A/S reported 34 stock positions worth $1.7 billion. Its top holding was VG Morningstar TS MKT ETF-US (VTI) at 18.2% of the portfolio, followed by Brookfield (BN, 9.7%) and Tempus AI Class A (TEM, 8.3%). Compared with Q3 2024, it opened 3 new positions, sold out of 6, added to 6 and reduced 6. The biggest buy was a new position in Recursion Pharmaceuticals-A (RXRX) and the biggest sale an exit from Corcept Therapeutics (CORT).

Most Recent 13F
Q2 2026
Location
HELLERUP, G7
CIK
0001388325
Portfolio Value
$1.7B (Q4 2024)
SEC Filing
0000950123-25-002801 ↗ filed Feb 14, 2025

Holdings Value

0$500.0M$1.0B$1.5B$2.0B$2.5B Q1 2024: $1.4B Q1 2024 Q2 2024: $1.9B Q2 2024 Q3 2024: $2.0B Q3 2024 Q4 2024: $1.7B $1.7B Q4 2024 Q1 2025: $1.3B Q1 2025 Q2 2025: $1.4B Q2 2025 Q3 2025: $1.6B Q3 2025 Q4 2025: $1.3B Q4 2025 Q1 2026: $1.2B Q1 2026 Q2 2026: $1.7B Q2 2026

Holdings 34 stocks · $1.7B

VTI VG Morningstar TS MKT ETF-US 18.22% 1,038,550 $301.0M No change
BN Brookfield Corp. 9.73% 2,798,830 $160.8M Reduce -19.8%
TEM Tempus AI Inc. Class A 8.33% 4,074,419 $137.6M No change
EWTX Edgewise Therapeutics Inc. 8.08% 5,000,000 $133.5M Reduce -9.9%
ASML ASML Holding NV-NY Reg SHS 6.96% 165,836 $114.9M Add +24.4%
CRM Salesforce Inc. 5.95% 293,901 $98.3M Reduce -20.3%
RXRX Recursion Pharmaceuticals-A 4.14% 10,114,633 $68.4M New
MIRM Mirum Pharmaceuticals Inc. 3.76% 1,500,000 $62.0M No change
PCVX Vaxcyte Inc. 3.72% 750,000 $61.4M No change
INSM Insmed Inc. 3.03% 724,666 $50.0M No change
CRNX Crinetics Pharmaceuticals Inc. 2.97% 960,215 $49.1M Reduce -4.0%
VRDN Viridian Therapeutics Inc. 2.61% 2,250,000 $43.1M Reduce -5.7%
AVBP Arrivent Biopharma Inc. 2.45% 1,520,627 $40.5M Add +1.0%
BABA Alibaba Group Holding-SP ADR 2.32% 452,327 $38.4M Reduce -9.7%
PHVS Pharvaris NV 2.00% 1,725,000 $33.1M No change
BMRN Biomarin Pharmaceutical Inc. 1.95% 490,000 $32.2M No change
MRUS Merus NV 1.91% 750,000 $31.5M Add +7.1%
CLDX Celldex Therapeutics Inc. 1.53% 1,000,000 $25.3M Add +3.8%
CRGX Cargo Therapeutics Inc. 1.45% 1,663,724 $24.0M Add +7.8%
FOLD Amicus Therapeutics Inc. 1.43% 2,500,000 $23.6M No change
LANZATECH GLOBAL INC 1.31% 15,814,845 $21.7M No change
BPMC Blueprint Medicines Corp. 0.92% 175,000 $15.3M No change
RCKT Rocket Pharmaceuticals Inc. 0.84% 1,100,000 $13.8M No change
VERV Verve Therapeutics Inc. 0.82% 2,400,000 $13.5M No change
ZBIO Zenas Biopharma Inc. 0.79% 1,600,000 $13.1M Add +39.1%
CBLL Ceribell Inc. 0.52% 328,809 $8.5M New
FDMT 4D Molecular Therapeutics Inc. 0.51% 1,500,000 $8.4M No change
LXEO Lexeo Therapeutics Inc. 0.45% 1,122,581 $7.4M No change
KYTX Kyverna Therapeutics Inc. 0.42% 1,850,000 $6.9M No change
MERSANA THERAPEUTICS INC 0.37% 4,250,000 $6.1M New
ABCL Abcellera Biologics Inc. 0.20% 1,126,915 $3.3M No change
IOBTQ Io Biotech Inc. 0.19% 3,354,449 $3.1M No change
MQ Marqeta Inc. 0.10% 441,558 $1.7M No change
DMRA Damora Therapeutics Inc. filed as GALECTO INC 0.03% 99,913 $465K No change

Portfolio Sells Q3 2024 → Q4 2024

CORT Corcept Therapeutics Inc. Sold out 0.00% −5.54
CABO Cable One Inc. Sold out 0.00% −2.06
ALNY Alnylam Pharmaceuticals Inc. Sold out 0.00% −1.62
BAM Brookfield Asset Mgmt-A Sold out 0.00% −1.47
BABA Alibaba Group Holding-SP ADR Reduce -9.7% 2.32% −0.32
MGX Metagenomi Therapeutics Inc. Sold out 0.00% −0.19
VRDN Viridian Therapeutics Inc. Reduce -5.7% 2.61% −0.08
SPRO Spero Therapeutics Inc. Sold out 0.00% −0.03
CRNX Crinetics Pharmaceuticals Inc. Reduce -4.0% 2.97% +0.43
BN Brookfield Corp. Reduce -19.8% 9.73% +0.52
EWTX Edgewise Therapeutics Inc. Reduce -9.9% 8.08% +0.73
CRM Salesforce Inc. Reduce -20.3% 5.95% +0.94

Portfolio Buys Q3 2024 → Q4 2024

RXRX Recursion Pharmaceuticals-A New 4.14% +4.14
ASML ASML Holding NV-NY Reg SHS Add +24.4% 6.96% +1.44
AVBP Arrivent Biopharma Inc. Add +1.0% 2.45% +0.70
CBLL Ceribell Inc. New 0.52% +0.52
MERSANA THERAPEUTICS INC New 0.37% +0.37
MRUS Merus NV Add +7.1% 1.91% +0.17
CRGX Cargo Therapeutics Inc. Add +7.8% 1.45% +0.04
CLDX Celldex Therapeutics Inc. Add +3.8% 1.53% −0.10
ZBIO Zenas Biopharma Inc. Add +39.1% 0.79% −0.17

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 25$1.7BEWTX, ASML, COAG, BN, MPLT
Q1 2026 22$1.2BEWTX, BN, ASML, MIRM, MPLT
Q4 2025 24$1.3BBN, EWTX, ASML, MIRM, CRM
Q3 2025 27$1.6BVTI, BN, ASML, MIRM, EWTX
Q2 2025 29$1.4BVTI, BN, ASML, CRM, MIRM
Q1 2025 31$1.3BVTI, BN, EWTX, ASML, CRM
Q4 2024 34$1.7BVTI, BN, TEM, EWTX, ASML
Q3 2024 37$2.0BVTI, TEM, BN, EWTX, CORT
Q2 2024Amended 38$1.9BVTI, BN, TEM, ASML, CRM
Q1 2024 35$1.4BASML, BN, CRM, EPC, CORT