Novo Holdings A/S

In its 13F for Q2 2025 (holdings as of June 30, 2025, filed August 14, 2025), Novo Holdings A/S reported 29 stock positions worth $1.4 billion. Its top holding was VG Morningstar TS MKT ETF-US (VTI) at 22.3% of the portfolio, followed by Brookfield (BN, 10.2%) and ASML Holding NV-NY Reg SHS (ASML, 9.4%). Compared with Q1 2025, it opened 3 new positions, sold out of 5, added to 10 and reduced 3. The biggest buy was a new position in Enliven Therapeutics (ELVN) and the biggest sale an exit from Amicus Therapeutics (FOLD).

Most Recent 13F
Q2 2026
Location
HELLERUP, G7
CIK
0001388325
Portfolio Value
$1.4B (Q2 2025)
SEC Filing
0001415889-25-021889 ↗ filed Aug 14, 2025

Holdings Value

0$500.0M$1.0B$1.5B$2.0B$2.5B Q1 2024: $1.4B Q1 2024 Q2 2024: $1.9B Q2 2024 Q3 2024: $2.0B Q3 2024 Q4 2024: $1.7B Q4 2024 Q1 2025: $1.3B Q1 2025 Q2 2025: $1.4B $1.4B Q2 2025 Q3 2025: $1.6B Q3 2025 Q4 2025: $1.3B Q4 2025 Q1 2026: $1.2B Q1 2026 Q2 2026: $1.7B Q2 2026

Holdings 29 stocks · $1.4B

VTI VG Morningstar TS MKT ETF-US 22.28% 1,038,550 $315.6M No change
BN Brookfield Corp. 10.18% 2,330,830 $144.2M No change
ASML ASML Holding NV-NY Reg SHS 9.38% 165,836 $132.9M No change
CRM Salesforce Inc. 6.36% 330,187 $90.0M Add +21.0%
MIRM Mirum Pharmaceuticals Inc. 5.39% 1,500,055 $76.3M Add +0.0%
EWTX Edgewise Therapeutics Inc. 4.95% 5,350,000 $70.1M No change
INSM Insmed Inc. 4.83% 680,000 $68.4M Reduce -6.2%
RXRX Recursion Pharmaceuticals-A 3.45% 9,665,128 $48.9M No change
CRNX Crinetics Pharmaceuticals Inc. 3.15% 1,550,000 $44.6M Add +21.6%
BABA Alibaba Group Holding-SP ADR 2.98% 372,327 $42.2M No change
AVBP Arrivent Biopharma Inc. 2.88% 1,872,142 $40.8M No change
MRUS Merus NV 2.78% 750,000 $39.5M Reduce -5.0%
BMRN Biomarin Pharmaceutical Inc. 2.56% 660,000 $36.3M Add +34.7%
BPMC Blueprint Medicines Corp. 2.40% 264,956 $34.0M Add +15.8%
VRDN Viridian Therapeutics Inc. 2.35% 2,380,000 $33.3M Add +5.8%
PHVS Pharvaris NV 2.14% 1,725,000 $30.4M No change
PCVX Vaxcyte Inc. 2.10% 916,160 $29.8M Add +0.1%
CLDX Celldex Therapeutics Inc. 1.72% 1,200,000 $24.4M No change
ZBIO Zenas Biopharma Inc. 1.54% 2,250,000 $21.8M Add +1.6%
ELVN Enliven Therapeutics Inc. 1.54% 1,084,432 $21.8M New
APGE Apogee Therapeutics Inc. 1.38% 449,392 $19.5M New
CBLL Ceribell Inc. 1.19% 900,000 $16.9M Add +2.3%
VALN Valneva SE - ADR 0.95% 2,375,000 $13.5M New
FDMT 4D Molecular Therapeutics Inc. 0.52% 2,000,000 $7.4M Add +2.6%
IOBTQ Io Biotech Inc. 0.33% 3,354,449 $4.7M No change
LANZATECH GLOBAL INC 0.30% 15,814,845 $4.3M No change
MQ Marqeta Inc. 0.18% 441,558 $2.6M No change
ABCL Abcellera Biologics Inc. 0.16% 652,529 $2.2M Reduce -42.1%
DMRA Damora Therapeutics Inc. filed as GALECTO INC 0.02% 99,913 $341K No change

Portfolio Sells Q1 2025 → Q2 2025

FOLD Amicus Therapeutics Inc. Sold out 0.00% −1.71
VERV Verve Therapeutics Inc. Sold out 0.00% −1.04
RCKT Rocket Pharmaceuticals Inc. Sold out 0.00% −0.56
LXEO Lexeo Therapeutics Inc. Sold out 0.00% −0.30
KYTX Kyverna Therapeutics Inc. Sold out 0.00% −0.27
ABCL Abcellera Biologics Inc. Reduce -42.1% 0.16% −0.03
MRUS Merus NV Reduce -5.0% 2.78% +0.26
INSM Insmed Inc. Reduce -6.2% 4.83% +0.63

Portfolio Buys Q1 2025 → Q2 2025

ELVN Enliven Therapeutics Inc. New 1.54% +1.54
APGE Apogee Therapeutics Inc. New 1.38% +1.38
VALN Valneva SE - ADR New 0.95% +0.95
BPMC Blueprint Medicines Corp. Add +15.8% 2.40% +0.86
CRM Salesforce Inc. Add +21.0% 6.36% +0.79
MIRM Mirum Pharmaceuticals Inc. Add +0.0% 5.39% +0.25
ZBIO Zenas Biopharma Inc. Add +1.6% 1.54% +0.21
FDMT 4D Molecular Therapeutics Inc. Add +2.6% 0.52% +0.04
VRDN Viridian Therapeutics Inc. Add +5.8% 2.35% +0.04
BMRN Biomarin Pharmaceutical Inc. Add +34.7% 2.56% −0.07
CBLL Ceribell Inc. Add +2.3% 1.19% −0.10
CRNX Crinetics Pharmaceuticals Inc. Add +21.6% 3.15% −0.11
PCVX Vaxcyte Inc. Add +0.1% 2.10% −0.53

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 25$1.7BEWTX, ASML, COAG, BN, MPLT
Q1 2026 22$1.2BEWTX, BN, ASML, MIRM, MPLT
Q4 2025 24$1.3BBN, EWTX, ASML, MIRM, CRM
Q3 2025 27$1.6BVTI, BN, ASML, MIRM, EWTX
Q2 2025 29$1.4BVTI, BN, ASML, CRM, MIRM
Q1 2025 31$1.3BVTI, BN, EWTX, ASML, CRM
Q4 2024 34$1.7BVTI, BN, TEM, EWTX, ASML
Q3 2024 37$2.0BVTI, TEM, BN, EWTX, CORT
Q2 2024Amended 38$1.9BVTI, BN, TEM, ASML, CRM
Q1 2024 35$1.4BASML, BN, CRM, EPC, CORT