Orion Investment Co

In its 13F for Q3 2025 (holdings as of September 30, 2025, filed November 13, 2025), Orion Investment Co reported 70 stock positions worth $314.7 million. Its top holding was Microsoft (MSFT) at 17.4% of the portfolio, followed by Palantir Technologies Class A (PLTR, 7.8%) and Qualcomm (QCOM, 6.4%). Compared with Q2 2025, it opened 2 new positions, sold out of 2, added to 26 and reduced 15. The biggest buy was Ionis Pharmaceuticals (IONS, shares +3%) and the biggest sale an exit from Blueprint Medicines (BPMC).

Most Recent 13F
Q2 2026
Location
ST. LOUIS, MO
CIK
0002033920
Portfolio Value
$314.7M (Q3 2025)
SEC Filing
0002033920-25-000005 ↗ filed Nov 13, 2025

Holdings Value

0$100.0M$200.0M$300.0M$400.0M Q2 2024: $251.0M Q2 2024 Q3 2024: $257.2M Q3 2024 Q4 2024: $250.7M Q4 2024 Q1 2025: $244.6M Q1 2025 Q2 2025: $282.5M Q2 2025 Q3 2025: $314.7M $314.7M Q3 2025 Q4 2025: $328.2M Q4 2025 Q1 2026: $315.1M Q1 2026 Q2 2026: $342.7M Q2 2026

Holdings 70 stocks · $314.7M
MSFT Microsoft Corp. 17.37% 105,512 $54.7M Add +0.1%
PLTR Palantir Technologies Inc. Class A 7.79% 134,364 $24.5M Reduce -0.1%
QCOM Qualcomm Inc. 6.39% 120,914 $20.1M Reduce -0.3%
REGN Regeneron Pharmaceuticals 5.47% 30,637 $17.2M Add +1.2%
IONQ Ionq Inc. 5.38% 275,234 $16.9M Add +1.4%
IONS Ionis Pharmaceuticals Inc. 4.67% 224,705 $14.7M Add +3.4%
PH Parker Hannifin Corp. 3.32% 13,765 $10.4M Add +0.4%
CMI Cummins Inc. 3.05% 22,711 $9.6M Add +0.4%
XOM Exxon Mobil Corp. 3.04% 84,768 $9.6M Add +0.7%
PG The Procter & Gamble Co. 2.89% 59,102 $9.1M Add +0.5%
ABT Abbott Laboratories 2.71% 63,659 $8.5M Reduce -0.9%
NEE Nextera Energy Inc. 2.45% 102,140 $7.7M Add +0.4%
SHOP Shopify Inc. Class A 2.30% 48,722 $7.2M Add +9.5%
HSY The Hershey Co. 2.28% 38,356 $7.2M Add +1.9%
GD General Dynamics Corp. 2.16% 19,907 $6.8M Add +0.5%
RGLD Royal Gold Inc. 1.77% 27,730 $5.6M Add +2.3%
BIIB Biogen Inc. 1.76% 39,429 $5.5M Add +19.8%
ASML ASML Holding NV-NY Reg SHS 1.64% 5,325 $5.2M Add +35.0%
INTC Intel Corp. 1.59% 149,536 $5.0M Reduce -0.6%
CCJ Cameco Corp. 1.35% 50,580 $4.2M Add +11.7%
RGTI Rigetti Computing Inc. 1.32% 139,230 $4.1M Add +52.3%
IOVA Iovance Biotherapeutics Inc. 1.28% 1,851,784 $4.0M Reduce -20.8%
CDNS Cadence Design SYS Inc. 1.16% 10,426 $3.7M Add +1.9%
AAPL Apple Inc. 1.16% 14,313 $3.6M No change
HII Huntington Ingalls Industrie 1.15% 12,556 $3.6M Add +1.2%
VOO Vanguard S&P 500 ETF 1.11% 5,713 $3.5M Add +0.9%
CNI Canadian Natl Railway Co. 0.99% 33,113 $3.1M Reduce -0.5%
ATO Atmos Energy Corp. 0.96% 17,667 $3.0M Add +13.9%
NEM Newmont Corp. 0.75% 27,920 $2.4M Add +5.7%
EFX Equifax Inc. 0.72% 8,887 $2.3M No change
NOW ServiceNow Inc. 0.71% 2,411 $2.2M Add +8.7%
PANW Palo Alto Networks Inc. 0.68% 10,492 $2.1M Add +1.9%
MRK Merck & Co. Inc. 0.55% 20,574 $1.7M Reduce -2.8%
IBOC International Bancshares CRP 0.50% 5,610 $1.6M No change
SR Spire Inc. 0.46% 17,704 $1.4M Reduce -3.3%
ABBV Abbvie Inc. 0.45% 6,116 $1.4M No change
AEE Ameren Corporation 0.45% 13,427 $1.4M Reduce -1.7%
AVGO Broadcom Inc. 0.41% 3,886 $1.3M New
EMR Emerson Electric Co. 0.38% 9,196 $1.2M No change
BMY Bristol-Myers Squibb Co. 0.35% 24,458 $1.1M Reduce -3.0%
GOOGL Alphabet Inc. Class A 0.34% 4,425 $1.1M No change
AMZN Amazon.com Inc. 0.34% 4,896 $1.1M Add +1.0%
EPD Enterprise Products Partners 0.33% 33,177 $1.0M Add +61.7%
OKLO Oklo Inc. 0.30% 8,428 $941K New
JNJ Johnson & Johnson 0.29% 4,973 $922K No change
BRK.B Berkshire Hathaway Inc. Class B 0.27% 1,678 $844K Reduce -10.7%
ARLP Alliance Resource Partners 0.23% 28,475 $720K Reduce -2.5%
CBSH Commerce Bancshares Inc. 0.21% 11,242 $672K No change
GOOG Alphabet Inc. Class C 0.19% 2,450 $597K No change
PYPL PayPal Holdings Inc. 0.19% 8,859 $594K No change
SHEL Shell PLC-ADR 0.18% 7,989 $571K No change
SO The Southern Co. 0.18% 5,845 $554K Reduce -2.8%
MO Altria Group Inc. 0.17% 8,296 $548K No change
AFL Aflac Inc. 0.16% 4,400 $491K No change
WMT Walmart Inc. 0.15% 4,656 $480K No change
META Meta Platforms Inc. Class A 0.14% 595 $437K No change
PFE Pfizer Inc. 0.13% 16,600 $423K No change
BA The Boeing Co. 0.13% 1,904 $411K No change
MKC McCormick & Co.-Non VTG SHRS 0.13% 6,120 $409K Reduce -3.9%
KO The Coca-Cola Co. 0.13% 6,083 $403K No change
LLY Eli Lilly & Co. 0.11% 471 $359K No change
HD Home Depot Inc. 0.10% 800 $324K No change
GRMN Garmin Ltd. 0.09% 1,200 $295K No change
CVX Chevron Corp. 0.09% 1,817 $282K Reduce -2.7%
ORCL Oracle Corp. 0.09% 995 $280K No change
UNP Union Pacific Corp. 0.09% 1,165 $275K No change
CAT Caterpillar Inc. 0.09% 575 $274K No change
MCD McDonald's Corp. 0.08% 860 $261K No change
PM Philip Morris International 0.08% 1,578 $256K No change
PEP Pepsico Inc. 0.08% 1,752 $246K No change

Portfolio Sells Q2 2025 → Q3 2025
BPMC Blueprint Medicines Corp. Sold out 0.00% −4.82
QCOM Qualcomm Inc. Reduce -0.3% 6.39% −0.45
ABT Abbott Laboratories Reduce -0.9% 2.71% −0.38
CNI Canadian Natl Railway Co. Reduce -0.5% 0.99% −0.23
IOVA Iovance Biotherapeutics Inc. Reduce -20.8% 1.28% −0.15
UNH Unitedhealth Group Inc. Sold out 0.00% −0.12
BMY Bristol-Myers Squibb Co. Reduce -3.0% 0.35% −0.06
BRK.B Berkshire Hathaway Inc. Class B Reduce -10.7% 0.27% −0.05
MRK Merck & Co. Inc. Reduce -2.8% 0.55% −0.04
ARLP Alliance Resource Partners Reduce -2.5% 0.23% −0.04
MKC McCormick & Co.-Non VTG SHRS Reduce -3.9% 0.13% −0.04
SO The Southern Co. Reduce -2.8% 0.18% −0.02
AEE Ameren Corporation Reduce -1.7% 0.45% −0.02
SR Spire Inc. Reduce -3.3% 0.46% −0.01
CVX Chevron Corp. Reduce -2.7% 0.09% −0.01
INTC Intel Corp. Reduce -0.6% 1.59% +0.40
PLTR Palantir Technologies Inc. Class A Reduce -0.1% 7.79% +1.30

Portfolio Buys Q2 2025 → Q3 2025
IONS Ionis Pharmaceuticals Inc. Add +3.4% 4.67% +1.63
IONQ Ionq Inc. Add +1.4% 5.38% +1.25
RGTI Rigetti Computing Inc. Add +52.3% 1.32% +0.93
ASML ASML Holding NV-NY Reg SHS Add +35.0% 1.64% +0.52
SHOP Shopify Inc. Class A Add +9.5% 2.30% +0.48
CMI Cummins Inc. Add +0.4% 3.05% +0.42
AVGO Broadcom Inc. New 0.41% +0.41
OKLO Oklo Inc. New 0.30% +0.30
BIIB Biogen Inc. Add +19.8% 1.76% +0.29
NEM Newmont Corp. Add +5.7% 0.75% +0.20
CCJ Cameco Corp. Add +11.7% 1.35% +0.16
GD General Dynamics Corp. Add +0.5% 2.16% +0.11
ATO Atmos Energy Corp. Add +13.9% 0.96% +0.11
EPD Enterprise Products Partners Add +61.7% 0.33% +0.10
HII Huntington Ingalls Industrie Add +1.2% 1.15% +0.09
HSY The Hershey Co. Add +1.9% 2.28% +0.07
RGLD Royal Gold Inc. Add +2.3% 1.77% +0.06
CDNS Cadence Design SYS Inc. Add +1.9% 1.16% +0.05
VOO Vanguard S&P 500 ETF Add +0.9% 1.11% −0.03
AMZN Amazon.com Inc. Add +1.0% 0.34% −0.03
NEE Nextera Energy Inc. Add +0.4% 2.45% −0.05
PANW Palo Alto Networks Inc. Add +1.9% 0.68% −0.07
PH Parker Hannifin Corp. Add +0.4% 3.32% −0.07
NOW ServiceNow Inc. Add +8.7% 0.71% −0.10
REGN Regeneron Pharmaceuticals Add +1.2% 5.47% −0.15
XOM Exxon Mobil Corp. Add +0.7% 3.04% −0.18
PG The Procter & Gamble Co. Add +0.5% 2.89% −0.43
MSFT Microsoft Corp. Add +0.1% 17.37% −1.20

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 73$342.7MMSFT, QCOM, INTC, REGN, IONS
Q1 2026 69$315.1MMSFT, REGN, PLTR, IONS, QCOM
Q4 2025 68$328.2MMSFT, PLTR, REGN, QCOM, IONS
Q3 2025 70$314.7MMSFT, PLTR, QCOM, REGN, IONQ
Q2 2025 70$282.5MMSFT, QCOM, PLTR, REGN, BPMC
Q1 2025 68$244.6MMSFT, REGN, QCOM, PLTR, XOM
Q4 2024 65$250.7MMSFT, REGN, QCOM, IONQ, PG
Q3 2024 66$257.2MMSFT, REGN, QCOM, PG, BPMC
Q2 2024 64$251.0MMSFT, REGN, QCOM, BPMC, IONS