Orion Investment Co
In its 13F for Q4 2025 (holdings as of December 31, 2025, filed February 11, 2026), Orion Investment Co reported 68 stock positions worth $328.2 million. Its top holding was Microsoft (MSFT) at 15.6% of the portfolio, followed by Palantir Technologies Class A (PLTR, 7.3%) and Regeneron Pharmaceuticals (REGN, 7.2%). Compared with Q3 2025, it opened 1 new position, sold out of 3, added to 27 and reduced 19. The biggest buy was Regeneron Pharmaceuticals (REGN, shares +1%) and the biggest sale Abbott Laboratories (ABT, shares −0%).
- Most Recent 13F
- Q2 2026
- Location
- ST. LOUIS, MO
- CIK
- 0002033920
- Portfolio Value
- $328.2M (Q4 2025)
- SEC Filing
- 0002033920-26-000001 ↗ filed Feb 11, 2026
Holdings Value
Holdings 68 stocks · $328.2M
| MSFT Microsoft Corp. | 15.55% | 105,549 | $51.0M | Add +0.0% |
| PLTR Palantir Technologies Inc. Class A | 7.28% | 134,468 | $23.9M | Add +0.1% |
| REGN Regeneron Pharmaceuticals | 7.25% | 30,812 | $23.8M | Add +0.6% |
| QCOM Qualcomm Inc. | 6.29% | 120,663 | $20.6M | Reduce -0.2% |
| IONS Ionis Pharmaceuticals Inc. | 5.43% | 225,161 | $17.8M | Add +0.2% |
| IONQ Ionq Inc. | 3.79% | 277,184 | $12.4M | Add +0.7% |
| PH Parker Hannifin Corp. | 3.69% | 13,763 | $12.1M | Reduce -0.0% |
| CMI Cummins Inc. | 3.54% | 22,785 | $11.6M | Add +0.3% |
| XOM Exxon Mobil Corp. | 3.11% | 84,744 | $10.2M | Reduce -0.0% |
| PG The Procter & Gamble Co. | 2.58% | 59,115 | $8.5M | Add +0.0% |
| NEE Nextera Energy Inc. | 2.51% | 102,769 | $8.3M | Add +0.6% |
| ABT Abbott Laboratories | 2.43% | 63,649 | $8.0M | Reduce -0.0% |
| SHOP Shopify Inc. Class A | 2.43% | 49,480 | $8.0M | Add +1.6% |
| HSY The Hershey Co. | 2.13% | 38,391 | $7.0M | Add +0.1% |
| BIIB Biogen Inc. | 2.11% | 39,404 | $6.9M | Reduce -0.1% |
| GD General Dynamics Corp. | 2.04% | 19,912 | $6.7M | Add +0.0% |
| RGLD Royal Gold Inc. | 2.02% | 29,798 | $6.6M | Add +7.5% |
| ASML ASML Holding NV-NY Reg SHS | 1.74% | 5,327 | $5.7M | Add +0.0% |
| INTC Intel Corp. | 1.68% | 149,264 | $5.5M | Reduce -0.2% |
| IOVA Iovance Biotherapeutics Inc. | 1.54% | 1,856,934 | $5.1M | Add +0.3% |
| CCJ Cameco Corp. | 1.46% | 52,238 | $4.8M | Add +3.3% |
| HII Huntington Ingalls Industrie | 1.29% | 12,476 | $4.2M | Reduce -0.6% |
| AAPL Apple Inc. | 1.19% | 14,354 | $3.9M | Add +0.3% |
| VOO Vanguard S&P 500 ETF | 1.12% | 5,843 | $3.7M | Add +2.3% |
| RGTI Rigetti Computing Inc. | 1.09% | 161,270 | $3.6M | Add +15.8% |
| CDNS Cadence Design SYS Inc. | 1.02% | 10,684 | $3.3M | Add +2.5% |
| CNI Canadian Natl Railway Co. | 0.97% | 32,353 | $3.2M | Reduce -2.3% |
| ATO Atmos Energy Corp. | 0.95% | 18,658 | $3.1M | Add +5.6% |
| ARWR Arrowhead Pharmaceuticals Inc. | 0.94% | 46,370 | $3.1M | New |
| NEM Newmont Corp. | 0.86% | 28,172 | $2.8M | Add +0.9% |
| MRK Merck & Co. Inc. | 0.66% | 20,574 | $2.2M | No change |
| PANW Palo Alto Networks Inc. | 0.59% | 10,499 | $1.9M | Add +0.1% |
| EFX Equifax Inc. | 0.59% | 8,887 | $1.9M | No change |
| NOW ServiceNow Inc. | 0.56% | 12,000 | $1.8M | Reduce -0.5% |
| IBOC International Bancshares CRP | 0.51% | 5,610 | $1.7M | No change |
| SR Spire Inc. | 0.45% | 17,704 | $1.5M | No change |
| ABBV Abbvie Inc. | 0.43% | 6,116 | $1.4M | No change |
| GOOGL Alphabet Inc. Class A | 0.42% | 4,379 | $1.4M | Reduce -1.0% |
| AVGO Broadcom Inc. | 0.41% | 3,922 | $1.4M | Add +0.9% |
| AEE Ameren Corporation | 0.41% | 13,327 | $1.3M | Reduce -0.7% |
| EMR Emerson Electric Co. | 0.37% | 9,196 | $1.2M | No change |
| BMY Bristol-Myers Squibb Co. | 0.36% | 22,148 | $1.2M | Reduce -9.4% |
| AMZN Amazon.com Inc. | 0.35% | 4,920 | $1.1M | Add +0.5% |
| EPD Enterprise Products Partners | 0.35% | 35,367 | $1.1M | Add +6.6% |
| JNJ Johnson & Johnson | 0.31% | 4,858 | $1.0M | Reduce -2.3% |
| BRK.B Berkshire Hathaway Inc. Class B | 0.26% | 1,678 | $843K | No change |
| ARLP Alliance Resource Partners | 0.24% | 34,475 | $801K | Add +21.1% |
| GOOG Alphabet Inc. Class C | 0.23% | 2,410 | $756K | Reduce -1.6% |
| CBSH Commerce Bancshares Inc. | 0.19% | 11,804 | $618K | Add +5.0% |
| OKLO Oklo Inc. | 0.18% | 8,303 | $596K | Reduce -1.5% |
| SHEL Shell PLC-ADR | 0.18% | 7,989 | $587K | No change |
| SO The Southern Co. | 0.16% | 5,845 | $510K | No change |
| WMT Walmart Inc. | 0.15% | 4,506 | $502K | Reduce -3.2% |
| LLY Eli Lilly & Co. | 0.15% | 461 | $495K | Reduce -2.1% |
| AFL Aflac Inc. | 0.15% | 4,400 | $485K | No change |
| MO Altria Group Inc. | 0.15% | 8,296 | $478K | No change |
| KO The Coca-Cola Co. | 0.13% | 6,083 | $425K | No change |
| BA The Boeing Co. | 0.13% | 1,904 | $413K | No change |
| PFE Pfizer Inc. | 0.13% | 16,600 | $413K | No change |
| MKC McCormick & Co.-Non VTG SHRS | 0.12% | 5,990 | $408K | Reduce -2.1% |
| META Meta Platforms Inc. Class A | 0.12% | 595 | $393K | No change |
| CAT Caterpillar Inc. | 0.10% | 575 | $329K | No change |
| CVX Chevron Corp. | 0.08% | 1,817 | $277K | No change |
| HD Home Depot Inc. | 0.08% | 800 | $275K | No change |
| UNP Union Pacific Corp. | 0.08% | 1,165 | $269K | No change |
| MCD McDonald's Corp. | 0.08% | 850 | $260K | Reduce -1.2% |
| PM Philip Morris International | 0.08% | 1,578 | $253K | No change |
| GRMN Garmin Ltd. | 0.07% | 1,200 | $243K | No change |
Portfolio Sells Q3 2025 → Q4 2025
| ABT Abbott Laboratories | Reduce -0.0% | 2.43% | −0.28 |
| PYPL PayPal Holdings Inc. | Sold out | 0.00% | −0.19 |
| NOW ServiceNow Inc. | Reduce -0.5% | 0.56% | −0.14 |
| OKLO Oklo Inc. | Reduce -1.5% | 0.18% | −0.12 |
| QCOM Qualcomm Inc. | Reduce -0.2% | 6.29% | −0.10 |
| ORCL Oracle Corp. | Sold out | 0.00% | −0.09 |
| PEP Pepsico Inc. | Sold out | 0.00% | −0.08 |
| AEE Ameren Corporation | Reduce -0.7% | 0.41% | −0.04 |
| CNI Canadian Natl Railway Co. | Reduce -2.3% | 0.97% | −0.02 |
| MKC McCormick & Co.-Non VTG SHRS | Reduce -2.1% | 0.12% | −0.01 |
| MCD McDonald's Corp. | Reduce -1.2% | 0.08% | −0.00 |
| WMT Walmart Inc. | Reduce -3.2% | 0.15% | +0.00 |
| JNJ Johnson & Johnson | Reduce -2.3% | 0.31% | +0.01 |
| BMY Bristol-Myers Squibb Co. | Reduce -9.4% | 0.36% | +0.01 |
| LLY Eli Lilly & Co. | Reduce -2.1% | 0.15% | +0.04 |
| GOOG Alphabet Inc. Class C | Reduce -1.6% | 0.23% | +0.04 |
| XOM Exxon Mobil Corp. | Reduce -0.0% | 3.11% | +0.07 |
| GOOGL Alphabet Inc. Class A | Reduce -1.0% | 0.42% | +0.08 |
| INTC Intel Corp. | Reduce -0.2% | 1.68% | +0.08 |
| HII Huntington Ingalls Industrie | Reduce -0.6% | 1.29% | +0.14 |
| BIIB Biogen Inc. | Reduce -0.1% | 2.11% | +0.36 |
| PH Parker Hannifin Corp. | Reduce -0.0% | 3.69% | +0.37 |
Portfolio Buys Q3 2025 → Q4 2025
| REGN Regeneron Pharmaceuticals | Add +0.6% | 7.25% | +1.77 |
| ARWR Arrowhead Pharmaceuticals Inc. | New | 0.94% | +0.94 |
| IONS Ionis Pharmaceuticals Inc. | Add +0.2% | 5.43% | +0.76 |
| CMI Cummins Inc. | Add +0.3% | 3.54% | +0.50 |
| IOVA Iovance Biotherapeutics Inc. | Add +0.3% | 1.54% | +0.27 |
| RGLD Royal Gold Inc. | Add +7.5% | 2.02% | +0.25 |
| SHOP Shopify Inc. Class A | Add +1.6% | 2.43% | +0.13 |
| NEM Newmont Corp. | Add +0.9% | 0.86% | +0.11 |
| CCJ Cameco Corp. | Add +3.3% | 1.46% | +0.11 |
| ASML ASML Holding NV-NY Reg SHS | Add +0.0% | 1.74% | +0.10 |
| NEE Nextera Energy Inc. | Add +0.6% | 2.51% | +0.06 |
| AAPL Apple Inc. | Add +0.3% | 1.19% | +0.03 |
| EPD Enterprise Products Partners | Add +6.6% | 0.35% | +0.02 |
| ARLP Alliance Resource Partners | Add +21.1% | 0.24% | +0.02 |
| AVGO Broadcom Inc. | Add +0.9% | 0.41% | +0.01 |
| VOO Vanguard S&P 500 ETF | Add +2.3% | 1.12% | +0.00 |
| AMZN Amazon.com Inc. | Add +0.5% | 0.35% | +0.00 |
| ATO Atmos Energy Corp. | Add +5.6% | 0.95% | −0.01 |
| CBSH Commerce Bancshares Inc. | Add +5.0% | 0.19% | −0.03 |
| PANW Palo Alto Networks Inc. | Add +0.1% | 0.59% | −0.09 |
| GD General Dynamics Corp. | Add +0.0% | 2.04% | −0.11 |
| CDNS Cadence Design SYS Inc. | Add +2.5% | 1.02% | −0.15 |
| HSY The Hershey Co. | Add +0.1% | 2.13% | −0.15 |
| RGTI Rigetti Computing Inc. | Add +15.8% | 1.09% | −0.23 |
| PG The Procter & Gamble Co. | Add +0.0% | 2.58% | −0.30 |
| PLTR Palantir Technologies Inc. Class A | Add +0.1% | 7.28% | −0.51 |
| IONQ Ionq Inc. | Add +0.7% | 3.79% | −1.59 |
| MSFT Microsoft Corp. | Add +0.0% | 15.55% | −1.81 |
All Filings
| Quarter | Positions | 13F Reported Value | Top Holdings |
|---|---|---|---|
| Q2 2026 | 73 | $342.7M | MSFT, QCOM, INTC, REGN, IONS |
| Q1 2026 | 69 | $315.1M | MSFT, REGN, PLTR, IONS, QCOM |
| Q4 2025 | 68 | $328.2M | MSFT, PLTR, REGN, QCOM, IONS |
| Q3 2025 | 70 | $314.7M | MSFT, PLTR, QCOM, REGN, IONQ |
| Q2 2025 | 70 | $282.5M | MSFT, QCOM, PLTR, REGN, BPMC |
| Q1 2025 | 68 | $244.6M | MSFT, REGN, QCOM, PLTR, XOM |
| Q4 2024 | 65 | $250.7M | MSFT, REGN, QCOM, IONQ, PG |
| Q3 2024 | 66 | $257.2M | MSFT, REGN, QCOM, PG, BPMC |
| Q2 2024 | 64 | $251.0M | MSFT, REGN, QCOM, BPMC, IONS |