TRV GP V, LLC

In its 13F for Q4 2024 (holdings as of December 31, 2024, filed February 13, 2025), TRV GP V, LLC reported 3 stock positions worth $294.0 million. Its top holding was Septerna (SEPN) at 48.4% of the portfolio, followed by Rapport Therapeutics (RAPP, 43.1%) and Cargo Therapeutics (CRGX, 8.5%).

Most Recent 13F
Q2 2026
Location
Boston, MA
CIK
0001990717
Portfolio Value
$294.0M (Q4 2024)
SEC Filing
0000950123-25-002037 ↗ filed Feb 13, 2025

Holdings Value

0$100.0M$200.0M$300.0M$400.0M$500.0M Q4 2024: $294.0M $294.0M Q4 2024 Q1 2025: $125.1M Q1 2025 Q2 2025: $165.7M Q2 2025 Q3 2025: $353.5M Q3 2025 Q4 2025: $429.2M Q4 2025 Q1 2026: $401.0M Q1 2026 Q2 2026: $498.2M Q2 2026

Holdings 3 stocks · $294.0M
SEPN Septerna Inc. 48.42% 6,215,591 $142.3M —
RAPP Rapport Therapeutics Inc. 43.06% 7,135,233 $126.6M —
CRGX Cargo Therapeutics Inc. 8.52% 1,737,216 $25.1M —

Portfolio Sells Q4 2024

No earlier filing to compare with.

Portfolio Buys Q4 2024

No earlier filing to compare with.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 3$498.2MRAPP, SEPN, MAZE
Q1 2026 3$401.0MRAPP, SEPN, MAZE
Q4 2025 3$429.2MRAPP, SEPN, MAZE
Q3 2025 3$353.5MRAPP, SEPN, MAZE
Q2 2025 4$165.7MRAPP, SEPN, MAZE, CRGX
Q1 2025 4$125.1MRAPP, SEPN, MAZE, CRGX
Q4 2024 3$294.0MSEPN, RAPP, CRGX