TRV GP V, LLC

In its 13F for Q2 2025 (holdings as of June 30, 2025, filed August 8, 2025), TRV GP V, LLC reported 4 stock positions worth $165.7 million. Its top holding was Rapport Therapeutics (RAPP) at 49.0% of the portfolio, followed by Septerna (SEPN, 39.7%) and Maze Therapeutics (MAZE, 7.0%). Its holdings were unchanged from Q1 2025.

Most Recent 13F
Q2 2026
Location
Boston, MA
CIK
0001990717
Portfolio Value
$165.7M (Q2 2025)
SEC Filing
0000950123-25-007373 ↗ filed Aug 8, 2025

Holdings Value

0$100.0M$200.0M$300.0M$400.0M$500.0M Q4 2024: $294.0M Q4 2024 Q1 2025: $125.1M Q1 2025 Q2 2025: $165.7M $165.7M Q2 2025 Q3 2025: $353.5M Q3 2025 Q4 2025: $429.2M Q4 2025 Q1 2026: $401.0M Q1 2026 Q2 2026: $498.2M Q2 2026

Holdings 4 stocks · $165.7M
RAPP Rapport Therapeutics Inc. 48.98% 7,135,233 $81.1M No change
SEPN Septerna Inc. 39.66% 6,215,591 $65.7M No change
MAZE Maze Therapeutics Inc. 7.04% 950,800 $11.7M No change
CRGX Cargo Therapeutics Inc. 4.32% 1,737,216 $7.2M No change

Portfolio Sells Q1 2025 → Q2 2025
None this quarter.

Portfolio Buys Q1 2025 → Q2 2025
None this quarter.

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 3$498.2MRAPP, SEPN, MAZE
Q1 2026 3$401.0MRAPP, SEPN, MAZE
Q4 2025 3$429.2MRAPP, SEPN, MAZE
Q3 2025 3$353.5MRAPP, SEPN, MAZE
Q2 2025 4$165.7MRAPP, SEPN, MAZE, CRGX
Q1 2025 4$125.1MRAPP, SEPN, MAZE, CRGX
Q4 2024 3$294.0MSEPN, RAPP, CRGX