Vyne Therapeutics Inc.

13F holders, Q3 2025 (September 30)
33holders −11
7new positions
18sold out
$0.34avg. 13F price*

At the end of Q3 2025, 33 institutions reported holding Vyne Therapeutics Inc. in their 13F filings, down 11 from Q2 2025. 7 opened new positions and 18 sold out. The largest holders were Baker Bros. Advisors LP ($285K), Acorn Capital Advisors, LLC ($199K) and Shay Capital LLC ($165K).

Company
Vyne Therapeutics Inc.
CUSIP
92941V308
Latest filing quarter
Q2 2026

History

Number of 13F holders

01020304050 Q1 2024: 30Q1 2024Q2 2024: 30Q2 2024Q3 2024: 32Q3 2024Q4 2024: 34Q4 2024Q1 2025: 37Q1 2025Q2 2025: 44Q2 2025Q3 2025: 33Q3 2025Q4 2025: 43Q4 2025Q1 2026: 45Q1 2026Q2 2026: 45Q2 2026

Total Exit/New Position Q2 2025 → Q3 2025

InstitutionsTotal Value
New Positions7$562K
Exits18$9.6M

All 13F filers, Q2 2025 → Q3 2025: 2,190,298 shares bought and 6,314,210 shares sold, net −4,123,912 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 33 holders

Baker Bros. Advisors LP 0.00% New 851,353 $285K
Acorn Capital Advisors, LLC 0.10% Reduce -20.4% 586,572 $199K
Shay Capital LLC 0.03% New 492,577 $165K
Acadian Asset Management LLC 0.00% Add +1891.3% 446,414 $148K
Ikarian Capital, LLC 0.02% No change 290,000 $97K
Two Sigma Investments, LP 0.00% New 220,788 $74K
Vanguard Group Inc. 0.00% Reduce -61.6% 190,383 $64K
Jane Street Group, LLC 0.00% Add +17.9% 147,120 $49K
Geode Capital Management, LLC 0.00% Add +2.8% 137,122 $46K
Boothbay Fund Management, LLC 0.00% No change 106,459 $36K
Bridgeway Capital Management, LLC 0.00% No change 76,958 $26K
Susquehanna International Group, LLP 0.00% Reduce -0.1% 57,763 $19K
Two Sigma Advisers, LP 0.00% New 56,600 $19K
Rangeley Capital, LLC 0.02% New 50,000 $17K
Corsair Capital Management, L.P. 0.00% Add +400.0% 50,000 $17K
BlackRock, Inc. 0.00% No change 44,405 $15K
Gsa Capital Partners LLP 0.00% Add +166.8% 35,921 $12K
Northern Trust Corp. 0.00% No change 23,110 $8K
Commonwealth Equity Services, LLC 0.00% No change 18,298 $6K
State Street Corp. 0.00% No change 15,765 $5K
Harvest Investment Services, LLC 0.00% Reduce -78.5% 11,059 $4K
UBS Group AG 0.00% New 5,572 $2K
Tower Research Capital LLC (TRC) 0.00% Add +28.3% 3,597 $1K
Royal Bank of Canada 0.00% No change 2,440 $1K
Bank of America Corp. 0.00% Add +4.3% 1,532 $513
Mb, Levis & Associates, LLC 0.00% No change 1,041 $349
Morgan Stanley 0.00% Reduce -73.3% 911 $305
JPMorgan Chase & Co. 0.00% No change 146 $49
Wells Fargo & Company 0.00% No change 65 $22
Truvestments Capital LLC 0.00% No change 25 $8
NFSG Corp 0.00% New 10 $3
Cwm, LLC 0.00% No change 500 $0
Centerpoint Advisors, LLC 0.00% No change 350 $0

"% of holder's portfolio" is VYNE THERAPEUTICS INC's weight in each manager's 13F, not the share of Vyne Therapeutics Inc. the manager owns.