Vyne Therapeutics Inc.

13F holders, Q2 2025 (June 30)
44holders +7
14new positions
7sold out
2famous investors
$1.65avg. 13F price*

At the end of Q2 2025, 44 institutions reported holding Vyne Therapeutics Inc. in their 13F filings, up 7 from Q1 2025. 14 opened new positions and 7 sold out. The largest holders were Cormorant Asset Management, LP ($2.3M), Citadel Advisors ($1.7M) and Acorn Capital Advisors, LLC ($1.2M). 2 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).

Company
Vyne Therapeutics Inc.
CUSIP
92941V308
Latest filing quarter
Q2 2026

History

Number of 13F holders

01020304050 Q1 2024: 30Q1 2024Q2 2024: 30Q2 2024Q3 2024: 32Q3 2024Q4 2024: 34Q4 2024Q1 2025: 37Q1 2025Q2 2025: 44Q2 2025Q3 2025: 33Q3 2025Q4 2025: 43Q4 2025Q1 2026: 45Q1 2026Q2 2026: 45Q2 2026

Total Exit/New Position Q1 2025 → Q2 2025

InstitutionsTotal Value
New Positions14$4.6M
Exits7$3.0M

All 13F filers, Q1 2025 → Q2 2025: 3,328,525 shares bought and 2,390,046 shares sold, net +938,479 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 44 holders

Cormorant Asset Management, LP 0.17% New 1,370,938 $2.3M
Citadel Advisors 0.00% Reduce -5.5% 1,040,070 $1.7M
Acorn Capital Advisors, LLC 0.79% Reduce -6.3% 736,572 $1.2M
Adage Capital Partners Gp, L.L.C. 0.00% Add +87.2% 644,134 $1.1M
DAFNA Capital Management LLC 0.29% No change 636,103 $1.0M
Kennedy Capital Management LLC 0.02% New 570,740 $942K
Vanguard Group Inc. 0.00% Add +4.3% 496,297 $819K
Palo Alto Investors LP 0.16% No change 445,434 $735K
Patient Square Capital LP 0.19% Add +23.3% 317,033 $523K
Ikarian Capital, LLC 0.16% New 290,000 $479K
Exome Asset Management LLC 0.28% Reduce -54.9% 208,970 $345K
Schonfeld Strategic Advisors LLC 0.00% Add +90.6% 161,951 $267K
Geode Capital Management, LLC 0.00% Reduce -0.1% 133,329 $220K
Jane Street Group, LLC 0.00% New 124,822 $206K
Tetragon Partners GP Ltd 0.05% New 115,384 $190K
Boothbay Fund Management, LLC 0.01% New 106,459 $176K
Squarepoint Ops LLC 0.00% New 78,474 $129K
Bridgeway Capital Management, LLC 0.00% Add +48.1% 76,958 $127K
Prelude Capital Management, LLC 0.01% Reduce -54.4% 64,584 $107K
Susquehanna International Group, LLP 0.00% Add +0.1% 57,814 $95K
XTX Topco Ltd 0.00% Add +72.2% 56,908 $94K
Harvest Investment Services, LLC 0.02% New 51,326 $85K
BlackRock, Inc. 0.00% Reduce -46.2% 44,405 $73K
HRT Financial LP 0.00% Add +60.2% 42,037 $69K
Velan Capital Investment Management LP 0.05% New 30,000 $50K
Northern Trust Corp. 0.00% Reduce -3.6% 23,110 $38K
Raymond James Financial Inc. 0.00% New 22,164 $37K
Acadian Asset Management LLC 0.00% New 22,418 $36K
Commonwealth Equity Services, LLC 0.00% No change 18,298 $30K
State Street Corp. 0.00% No change 15,765 $26K
Gsa Capital Partners LLP 0.00% New 13,466 $22K
Renaissance Technologies 0.00% Reduce -90.8% 10,543 $17K
Corsair Capital Management, L.P. 0.00% New 10,000 $17K
Morgan Stanley 0.00% Reduce -73.4% 3,411 $6K
Tower Research Capital LLC (TRC) 0.00% Reduce -34.7% 2,804 $5K
Royal Bank of Canada 0.00% No change 2,440 $4K
Bank of America Corp. 0.00% Reduce -91.4% 1,469 $2K
Mb, Levis & Associates, LLC 0.00% No change 1,041 $2K
Centerpoint Advisors, LLC 0.00% No change 350 $1K
Cwm, LLC 0.00% No change 500 $1K
JPMorgan Chase & Co. 0.00% Reduce -97.6% 146 $241
Wells Fargo & Company 0.00% No change 65 $107
Truvestments Capital LLC 0.00% No change 25 $41
Northwestern Mutual Wealth Management Co. 0.00% New 11 $18

"% of holder's portfolio" is VYNE THERAPEUTICS INC's weight in each manager's 13F, not the share of Vyne Therapeutics Inc. the manager owns.