Vyne Therapeutics Inc.

13F holders, Q4 2025 (December 31)
43holders +10
10new positions
3sold out
1famous investor
$0.58avg. 13F price*

At the end of Q4 2025, 43 institutions reported holding Vyne Therapeutics Inc. in their 13F filings, up 10 from Q3 2025. 10 opened new positions and 3 sold out. The largest holders were Shay Capital LLC ($942K), Anson Funds Management LP ($739K) and Deeter Investments LLP ($580K). One famous investor held it Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Vyne Therapeutics Inc.
CUSIP
92941V308
Latest filing quarter
Q2 2026

History

Number of 13F holders

01020304050 Q1 2024: 30Q1 2024Q2 2024: 30Q2 2024Q3 2024: 32Q3 2024Q4 2024: 34Q4 2024Q1 2025: 37Q1 2025Q2 2025: 44Q2 2025Q3 2025: 33Q3 2025Q4 2025: 43Q4 2025Q1 2026: 45Q1 2026Q2 2026: 45Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions10$1.6M
Exits3$328K

All 13F filers, Q3 2025 → Q4 2025: 4,499,927 shares bought and 1,690,084 shares sold, net +2,809,843 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 43 holders

Shay Capital LLC 0.15% Add +229.8% 1,624,349 $942K
Anson Funds Management LP 0.10% New 1,274,386 $739K
Deeter Investments LLP 0.13% — 1,000,000 $580K
Nantahala Capital Management, LLC 0.03% New 1,000,000 $580K
T3 Companies, LLC 0.71% — 945,000 $548K
Acadian Asset Management LLC 0.00% Add +43.0% 638,492 $370K
KVP Capital Advisors, LP 0.30% — 500,551 $290K
Vanguard Group Inc. 0.00% Add +65.2% 314,545 $182K
Ikarian Capital, LLC 0.02% Reduce -8.7% 264,912 $154K
ADAR1 Capital Management, LLC 0.01% New 253,791 $147K
Geode Capital Management, LLC 0.00% Add +64.2% 225,152 $131K
Two Sigma Investments, LP 0.00% Reduce -0.4% 220,000 $128K
Two Sigma Advisers, LP 0.00% Add +188.2% 163,100 $95K
Susquehanna International Group, LLP 0.00% Add +73.7% 100,341 $58K
Rangeley Capital, LLC 0.05% Add +100.0% 100,000 $58K
Boothbay Fund Management, LLC 0.00% Reduce -23.6% 81,371 $47K
XTX Topco Ltd 0.00% New 79,040 $46K
Jane Street Group, LLC 0.00% Reduce -50.8% 72,356 $42K
UBS Group AG 0.00% Add +1026.4% 62,761 $36K
Gsa Capital Partners LLP 0.00% Add +50.2% 53,961 $31K
BlackRock, Inc. 0.00% No change 44,405 $26K
Citadel Advisors 0.00% New 30,526 $18K
Virtu Financial LLC 0.00% New 25,327 $15K
FNY Investment Advisers, LLC 0.00% New 25,000 $14K
Northern Trust Corp. 0.00% No change 23,110 $13K
Commonwealth Equity Services, LLC 0.00% No change 18,298 $11K
State Street Corp. 0.00% No change 15,765 $9K
Harvest Investment Services, LLC 0.00% No change 11,059 $6K
Tower Research Capital LLC (TRC) 0.00% Reduce -0.8% 3,567 $2K
Royal Bank of Canada 0.00% Add +0.0% 2,441 $1K
Bank of America Corp. 0.00% Add +9.5% 1,677 $973
Acorn Capital Advisors, LLC 0.00% Reduce -99.8% 1,425 $827
Mb, Levis & Associates, LLC 0.00% No change 1,041 $604
Northwestern Mutual Wealth Management Co. 0.00% New 800 $464
Hurley Capital, LLC 0.00% New 561 $325
JPMorgan Chase & Co. 0.00% No change 146 $85
Wells Fargo & Company 0.00% No change 65 $38
Morgan Stanley 0.00% Reduce -95.3% 43 $25
Truvestments Capital LLC 0.00% No change 25 $15
NFSG Corp 0.00% No change 10 $6
Cwm, LLC 0.00% No change 500 $0
Centerpoint Advisors, LLC 0.00% No change 350 $0
Motiv8 Investments LLC 0.00% New 1 $0

"% of holder's portfolio" is VYNE THERAPEUTICS INC's weight in each manager's 13F, not the share of Vyne Therapeutics Inc. the manager owns.