Acadia PharmaceuticalsACAD
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 336 institutions reported holding Acadia Pharmaceuticals Inc. (ACAD) in their 13F filings, up 2 from Q3 2025. 36 opened new positions and 41 sold out. The largest holders were Baker Bros. Advisors LP ($1.1B), BlackRock, Inc. ($554.4M) and Vanguard Group Inc. ($404.8M). 9 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Jim Simons / Peter Brown (0.1% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Acadia Pharmaceuticals Inc.
- CUSIP
- 004225108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 36 | $40.1M |
| Exits | 41 | $51.7M |
All 13F filers, Q3 2025 → Q4 2025: 11,989,964 shares bought and 16,791,282 shares sold, net −4,801,318 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 336 holders
| Baker Bros. Advisors LP | 6.74% | No change | 42,896,690 | $1.1B |
| BlackRock, Inc. | 0.01% | Add +2.4% | 20,755,452 | $554.4M |
| Vanguard Group Inc. | 0.01% | Reduce -0.2% | 15,153,957 | $404.8M |
| State Street Corp. | 0.01% | Add +9.0% | 7,910,733 | $211.3M |
| RTW Investments, LP | 1.91% | No change | 7,144,524 | $190.8M |
| Point72 Asset Management | 0.15% | Add +127.2% | 3,377,311 | $90.2M |
| Geode Capital Management, LLC | 0.01% | Add +3.4% | 3,239,451 | $86.5M |
| Dimensional Fund Advisors LP | 0.02% | Add +4.4% | 2,920,974 | $78.0M |
| Palo Alto Investors LP | 9.24% | Add +0.7% | 2,484,031 | $66.3M |
| First Trust Advisors LP | 0.04% | Add +16.8% | 2,270,034 | $60.6M |
| Braidwell LP | 2.08% | Reduce -14.6% | 2,032,021 | $54.3M |
| Goldman Sachs Group Inc. | 0.01% | Reduce -25.3% | 1,570,051 | $41.9M |
| Fred Alger Management, LLC | 0.16% | Reduce -0.5% | 1,559,962 | $41.7M |
| Pictet Asset Management Holding SA | 0.04% | Add +5.8% | 1,547,103 | $41.5M |
| Renaissance Technologies | 0.06% | Add +5.7% | 1,532,596 | $40.9M |
| Norges Bank | 0.00% | — | 1,507,527 | $40.3M |
| Arrowstreet Capital, Limited Partnership | 0.02% | Reduce -8.9% | 1,502,617 | $40.1M |
| Trails Edge Capital Partners, LP | 9.37% | — | 1,419,406 | $37.9M |
| Citadel Advisors | 0.03% | Add +322.7% | 1,367,459 | $36.5M |
| Frazier Life Sciences Management, L.P. | 0.93% | Add +111.3% | 1,297,198 | $34.6M |
| Northern Trust Corp. | 0.00% | Reduce -5.2% | 1,235,829 | $33.0M |
| Bank of America Corp. | 0.00% | Add +37.6% | 1,221,445 | $32.6M |
| Qube Research & Technologies Ltd | 0.05% | Add +101.6% | 1,202,601 | $32.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -2.6% | 1,172,317 | $31.3M |
| Morgan Stanley | 0.00% | Reduce -3.9% | 1,141,974 | $30.5M |
| Two Sigma Investments, LP | 0.05% | Add +68.1% | 1,119,117 | $29.9M |
| Rockefeller Capital Management L.P. | 0.05% | Add +7.4% | 1,113,040 | $29.7M |
| Massachusetts Financial Services Co. | 0.01% | Reduce -3.4% | 1,072,483 | $28.6M |
| Nuveen, LLC | 0.01% | Add +10.8% | 1,057,527 | $28.2M |
| D. E. Shaw & Co. | 0.02% | Reduce -34.2% | 1,026,785 | $27.4M |
| Logos Global Management LP | 1.51% | New | 850,000 | $22.7M |
| Invesco Ltd. | 0.00% | Add +14.5% | 847,961 | $22.6M |
| Deutsche Bank AG | 0.01% | Reduce -45.6% | 828,594 | $22.1M |
| Emerald Advisers, LLC | 0.67% | Add +42.4% | 811,197 | $21.7M |
| UBS Group AG | 0.00% | Add +15.7% | 769,392 | $20.6M |
| Bank of New York Mellon Corp | 0.00% | Reduce -5.5% | 751,985 | $20.1M |
| Principal Financial Group Inc. | 0.01% | Add +7.0% | 745,356 | $19.9M |
| FMR LLC | 0.00% | Add +9.2% | 726,963 | $19.4M |
| Panagora Asset Management Inc. | 0.06% | Add +3.7% | 681,102 | $18.2M |
| Fisher Asset Management | 0.01% | Add +4.2% | 665,087 | $17.8M |
| Ameriprise Financial Inc. | 0.00% | Reduce -3.3% | 662,241 | $17.7M |
| Allspring Global Investments Holdings, LLC | 0.03% | Add +25.4% | 658,813 | $17.3M |
| Voya Investment Management LLC | 0.02% | Reduce -6.4% | 641,511 | $17.1M |
| Jupiter Asset Management Ltd. | 0.13% | Add +30.4% | 621,049 | $16.6M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -44.1% | 615,169 | $16.4M |
| Algert Global LLC | 0.26% | Add +53.6% | 614,410 | $16.4M |
| AQR Capital Management | 0.01% | Reduce -2.6% | 604,748 | $16.2M |
| Rice Hall James & Associates, LLC | 0.89% | Reduce -1.8% | 603,740 | $16.1M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.04% | Reduce -13.1% | 580,969 | $15.5M |
| Millennium Management | 0.01% | Reduce -62.7% | 553,674 | $14.8M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -0.3% | 532,533 | $14.2M |
| Marshall Wace, LLP | 0.01% | Reduce -79.1% | 493,379 | $13.2M |
| Prudential Financial Inc. | 0.02% | Reduce -46.6% | 485,880 | $13.0M |
| Emerald Mutual Fund Advisers Trust | 0.63% | Add +53.6% | 484,506 | $12.9M |
| Glenmede Trust Co. NA | 0.06% | — | 453,643 | $12.1M |
| Public Sector Pension Investment Board | 0.04% | Reduce -11.0% | 433,247 | $11.6M |
| Jacobs Levy Equity Management, Inc. | 0.04% | Reduce -50.0% | 371,047 | $9.9M |
| Two Sigma Advisers, LP | 0.02% | Add +276.2% | 370,200 | $9.9M |
| Barclays PLC | 0.00% | Reduce -15.3% | 368,304 | $9.8M |
| Rhumbline Advisers | 0.01% | Reduce -7.8% | 361,086 | $9.6M |
| Man Group plc | 0.02% | Reduce -7.7% | 348,160 | $9.3M |
| Edgestream Partners, L.P. | 0.24% | Add +35.2% | 316,239 | $8.4M |
| Legal & General Group Plc | 0.00% | Reduce -6.1% | 314,351 | $8.4M |
| Great Lakes Advisors, LLC | 0.07% | Reduce -31.1% | 313,536 | $8.4M |
| Tang Capital Management LLC | 0.40% | Reduce -80.0% | 300,000 | $8.0M |
| Trexquant Investment LP | 0.07% | Add +30.6% | 297,802 | $8.0M |
| Allianz Asset Management GmbH | 0.01% | Add +827.0% | 295,476 | $7.9M |
| Royal Bank of Canada | 0.00% | Reduce -67.7% | 290,854 | $7.8M |
| Janus Henderson Group PLC | 0.00% | Add +464.3% | 290,111 | $7.7M |
| JPMorgan Chase & Co. | 0.00% | Reduce -16.9% | 270,826 | $7.2M |
| Nordea Investment Management AB | 0.01% | Reduce -15.2% | 237,645 | $6.3M |
| Swiss National Bank | 0.00% | Add +2.5% | 232,904 | $6.2M |
| Lazard Asset Management LLC | 0.01% | Add +30.9% | 226,222 | $6.0M |
| F/m Investments LLC | 0.23% | Add +342.9% | 224,005 | $6.0M |
| Sphera Funds Management LTD. | 1.18% | Add +42.5% | 212,202 | $5.7M |
| Wells Fargo & Company | 0.00% | Add +38.7% | 209,188 | $5.6M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -2.7% | 205,433 | $5.5M |
| Rafferty Asset Management, LLC | 0.02% | Add +1.7% | 198,263 | $5.3M |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 0.00% | Add +173.3% | 194,146 | $5.2M |
| Victory Capital Management Inc. | 0.00% | Reduce -26.3% | 177,605 | $4.7M |
| Eversept Partners, LP | 0.26% | Add +7.5% | 176,594 | $4.7M |
| Franklin Resources Inc. | 0.00% | Reduce -54.7% | 171,483 | $4.6M |
| Birchview Capital, LP | 2.67% | No change | 171,000 | $4.6M |
| Ishara Investments LP | 4.97% | — | 160,000 | $4.3M |
| Alps Advisors Inc. | 0.02% | Add +58.5% | 158,197 | $4.2M |
| Alliancebernstein L.P. | 0.00% | Add +0.8% | 156,243 | $4.2M |
| Sei Investments Co. | 0.00% | Add +57.2% | 154,130 | $4.1M |
| Envestnet Asset Management Inc. | 0.00% | Add +1.7% | 152,163 | $4.1M |
| State of Wisconsin Investment Board | 0.01% | Reduce -20.5% | 150,386 | $4.0M |
| Hussman Strategic Advisors, Inc. | 0.95% | Add +16.7% | 147,000 | $3.9M |
| Russell Investments Group, Ltd. | 0.00% | Add +75.1% | 138,296 | $3.7M |
| Bridgewater Associates | 0.01% | Reduce -15.3% | 138,179 | $3.7M |
| Axecap Investments, LLC | 2.25% | Reduce -32.8% | 136,676 | $3.7M |
| Erste Asset Management GmbH | 0.03% | No change | 133,700 | $3.6M |
| American Century Companies Inc. | 0.00% | Reduce -69.2% | 128,998 | $3.4M |
| State Board of Administration of Florida Retirement System | 0.01% | No change | 128,689 | $3.4M |
| California State Teachers Retirement System | 0.00% | Add +25.9% | 126,807 | $3.4M |
| Segall Bryant & Hamill, LLC | 0.05% | New | 126,066 | $3.4M |
| Acadian Asset Management LLC | 0.01% | Add +83.1% | 119,742 | $3.2M |
| Martingale Asset Management L P | 0.07% | Add +9.0% | 109,319 | $2.9M |
"% of holder's portfolio" is ACAD's weight in each manager's 13F, not the share of Acadia Pharmaceuticals Inc. the manager owns.