AgenusAGEN
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 96 institutions reported holding Agenus Inc. (AGEN) in their 13F filings, up 9 from Q3 2025. 20 opened new positions and 10 sold out. The largest holders were Vanguard Group Inc. ($8.9M), Siren, L.L.C. ($3.3M) and Acadian Asset Management LLC ($1.9M). 6 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Agenus Inc.
- CUSIP
- 00847G804
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 20 | $4.1M |
| Exits | 10 | $771K |
All 13F filers, Q3 2025 → Q4 2025: 2,825,105 shares bought and 1,410,173 shares sold, net +1,414,932 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 96 holders
| Vanguard Group Inc. | 0.00% | Add +10.2% | 2,830,736 | $8.9M |
| Siren, L.L.C. | 0.10% | No change | 1,064,250 | $3.3M |
| Acadian Asset Management LLC | 0.00% | Add +203.5% | 622,484 | $1.9M |
| BlackRock, Inc. | 0.00% | Add +2.0% | 558,345 | $1.8M |
| Renaissance Technologies | 0.00% | Add +721.1% | 543,546 | $1.7M |
| Citadel Advisors | 0.00% | New | 423,242 | $1.3M |
| Geode Capital Management, LLC | 0.00% | Add +7.4% | 372,748 | $1.2M |
| Morgan Stanley | 0.00% | Reduce -48.1% | 285,198 | $896K |
| Susquehanna International Group, LLP | 0.00% | Add +22.4% | 233,674 | $734K |
| Millennium Management | 0.00% | Reduce -35.4% | 225,339 | $708K |
| Jump Financial, LLC | 0.01% | Add +20.4% | 170,407 | $535K |
| Panagora Asset Management Inc. | 0.00% | Add +29.3% | 163,148 | $512K |
| Marshall Wace, LLP | 0.00% | Add +29.6% | 146,800 | $461K |
| Raymond James Financial Inc. | 0.00% | Reduce -2.8% | 141,653 | $445K |
| State Street Corp. | 0.00% | Reduce -8.8% | 137,383 | $431K |
| D. E. Shaw & Co. | 0.00% | Add +11.6% | 127,638 | $401K |
| Walleye Capital LLC | 0.00% | Reduce -60.3% | 123,458 | $388K |
| UBS Group AG | 0.00% | Add +45.0% | 118,818 | $373K |
| Two Sigma Investments, LP | 0.00% | Add +14.4% | 117,117 | $368K |
| 683 Capital Management, LLC | 0.03% | New | 114,336 | $359K |
| Man Group plc | 0.00% | New | 114,204 | $359K |
| Point72 Asset Management | 0.00% | New | 108,220 | $340K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 100,500 | $316K |
| Northern Trust Corp. | 0.00% | Add +9.7% | 89,586 | $281K |
| Jane Street Group, LLC | 0.00% | Add +39.4% | 73,572 | $231K |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | New | 67,959 | $213K |
| Canada Pension Plan Investment Board | 0.00% | New | 66,100 | $208K |
| Goldman Sachs Group Inc. | 0.00% | Add +35.1% | 61,749 | $194K |
| Susquehanna Portfolio Strategies, LLC | 0.00% | Reduce -64.7% | 59,413 | $187K |
| Squarepoint Ops LLC | 0.00% | Add +294.9% | 55,142 | $173K |
| ExodusPoint Capital Management, LP | 0.00% | New | 47,461 | $149K |
| Barclays PLC | 0.00% | Add +352.8% | 46,273 | $145K |
| Avestar Capital, LLC | 0.01% | No change | 41,000 | $129K |
| Qube Research & Technologies Ltd | 0.00% | New | 39,895 | $125K |
| Engineers Gate Manager LP | 0.00% | Add +0.1% | 35,279 | $111K |
| Virtu Financial LLC | 0.00% | New | 34,385 | $108K |
| Two Sigma Advisers, LP | 0.00% | New | 34,245 | $108K |
| Graham Capital Management, L.P. | 0.00% | Reduce -42.2% | 31,706 | $100K |
| Ovata Capital Management Ltd | 0.01% | New | 30,800 | $97K |
| Captrust Financial Advisors | 0.00% | Reduce -1.9% | 30,087 | $94K |
| Key Client Fiduciary Advisors, LLC | 0.03% | Reduce -30.3% | 27,348 | $86K |
| Osaic Holdings, Inc. | 0.00% | Reduce -20.1% | 27,139 | $85K |
| HighTower Advisors, LLC | 0.00% | Reduce -0.6% | 25,142 | $79K |
| T. Rowe Price Associates Inc. | 0.00% | New | 24,500 | $77K |
| LPL Financial LLC | 0.00% | Add +20.3% | 23,326 | $73K |
| Group One Trading LLC | 0.00% | New | 22,239 | $70K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -1.6% | 19,831 | $62K |
| Lighthouse Investment Partners, LLC | 0.00% | New | 18,720 | $59K |
| HSBC Holdings PLC | 0.00% | No change | 17,056 | $54K |
| Quadrature Capital Ltd | 0.00% | New | 17,121 | $54K |
| Bank of Montreal | 0.00% | Add +0.0% | 16,207 | $51K |
| Sherbrooke Park Advisers LLC | 0.12% | Reduce -7.0% | 15,390 | $48K |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -0.0% | 15,061 | $47K |
| Prelude Capital Management, LLC | 0.00% | New | 14,500 | $46K |
| Redwood Family Wealth LLC | 0.04% | — | 14,140 | $44K |
| Bank of America Corp. | 0.00% | Reduce -96.4% | 13,246 | $42K |
| R Squared Ltd | 0.02% | New | 13,129 | $41K |
| Post Resch Tallon Group Inc. | 0.03% | Reduce -36.3% | 12,750 | $40K |
| AQR Capital Management | 0.00% | Reduce -57.6% | 11,576 | $36K |
| Values First Advisors, Inc. | 0.02% | Reduce -17.0% | 11,065 | $35K |
| NewEdge Advisors, LLC | 0.00% | Reduce -76.2% | 10,596 | $33K |
| Wells Fargo & Company | 0.00% | Reduce -23.6% | 10,184 | $32K |
| MSA Advisors, LLC | 0.01% | No change | 10,000 | $31K |
| EP Wealth Advisors, LLC | 0.00% | — | 10,000 | $31K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +51.5% | 8,402 | $26K |
| FMR LLC | 0.00% | Reduce -4.6% | 5,429 | $17K |
| First Command Advisory Services, Inc. | 0.00% | No change | 3,530 | $11K |
| Pinnacle Wealth Planning Services, Inc. | 0.00% | New | 3,373 | $11K |
| Royal Bank of Canada | 0.00% | Reduce -83.4% | 2,129 | $7K |
| CoreCap Advisors, LLC | 0.00% | No change | 2,000 | $6K |
| Cwm, LLC | 0.00% | Reduce -61.4% | 1,917 | $6K |
| Optiver Holding B.V. | 0.00% | Add +6765.0% | 1,373 | $4K |
| Chilton Capital Management LLC | 0.00% | No change | 1,058 | $3K |
| Covestor Ltd | 0.00% | No change | 1,011 | $3K |
| Northwestern Mutual Wealth Management Co. | 0.00% | Reduce -10.6% | 633 | $2K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 621 | $2K |
| Game Plan Financial Advisors, LLC | 0.00% | No change | 585 | $2K |
| Rhumbline Advisers | 0.00% | No change | 538 | $2K |
| Huntington National Bank | 0.00% | No change | 500 | $2K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -86.5% | 433 | $1K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 410 | $1K |
| JPMorgan Chase & Co. | 0.00% | Reduce -98.7% | 382 | $1K |
| Jones Financial Companies LLLP | 0.00% | No change | 371 | $1K |
| Rialto Wealth Management, LLC | 0.00% | No change | 305 | $958 |
| Fortitude Family Office, LLC | 0.00% | No change | 296 | $929 |
| EverSource Wealth Advisors, LLC | 0.00% | No change | 274 | $860 |
| Atlantic Union Bankshares Corp | 0.00% | No change | 250 | $785 |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 100 | $314 |
| BNP Paribas Financial Markets | 0.00% | Add +24.7% | 96 | $301 |
| Allworth Financial LP | 0.00% | Add +625.0% | 58 | $183 |
| Root Financial Partners, LLC | 0.00% | No change | 25 | $79 |
| IFP Advisors, Inc | 0.00% | Reduce -6.3% | 15 | $47 |
| Horizon Financial Services, LLC | 0.00% | New | 9 | $28 |
| Arax Advisory Partners | 0.00% | Reduce -99.3% | 5 | $16 |
| Parallel Advisors, LLC | 0.00% | Reduce -79.2% | 5 | $16 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -98.4% | 5 | $16 |
"% of holder's portfolio" is AGEN's weight in each manager's 13F, not the share of Agenus Inc. the manager owns.