Applied TherapeuticsAPLT

13F holders, Q3 2025 (September 30)
70holders −5
11new positions
16sold out
3famous investors
$0.60avg. 13F price*

At the end of Q3 2025, 70 institutions reported holding Applied Therapeutics Inc. (APLT) in their 13F filings, down 5 from Q2 2025. 11 opened new positions and 16 sold out. The largest holders were T. Rowe Price Investment Management, Inc. ($12.8M), Vestal Point Capital, LP ($8.6M) and Propel Bio Management, LLC ($6.8M). 3 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).

Company
Applied Therapeutics Inc.
CUSIP
03828A101
Latest filing quarter
Q4 2025

History

Number of 13F holders

050100150 Q1 2024: 89Q1 2024Q2 2024: 94Q2 2024Q3 2024: 126Q3 2024Q4 2024: 119Q4 2024Q1 2025: 90Q1 2025Q2 2025: 75Q2 2025Q3 2025: 70Q3 2025Q4 2025: 52Q4 2025

Total Exit/New Position Q2 2025 → Q3 2025

InstitutionsTotal Value
New Positions11$2.6M
Exits16$1.3M

All 13F filers, Q2 2025 → Q3 2025: 14,385,247 shares bought and 7,682,169 shares sold, net +6,703,078 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 70 holders

T. Rowe Price Investment Management, Inc. 0.01% Add +14.6% 21,403,300 $12.8M
Vestal Point Capital, LP 0.39% Add +23.9% 14,250,000 $8.6M
Propel Bio Management, LLC 6.83% No change 11,285,420 $6.8M
Knoll Capital Management, LLC 2.52% No change 7,799,687 $4.7M
Vanguard Group Inc. 0.00% Add +7.8% 5,102,689 $3.1M
Simplify Asset Management Inc. 0.06% No change 4,487,505 $2.7M
BlackRock, Inc. 0.00% Reduce -26.4% 3,843,733 $2.3M
PNC Financial Services Group, Inc. 0.00% New 2,901,184 $1.8M
Pathstone Holdings, LLC 0.01% No change 2,643,540 $1.6M
Marshall Wace, LLP 0.00% Add +64.7% 2,542,688 $1.5M
Adage Capital Partners Gp, L.L.C. 0.00% Add +82.5% 2,211,629 $1.3M
Rock Springs Capital Management LP 0.07% No change 2,075,991 $1.3M
Franklin Resources Inc. 0.00% No change 2,003,338 $1.2M
Millennium Management 0.00% Reduce -1.9% 1,907,214 $1.2M
UBS Group AG 0.00% Add +129.4% 1,905,625 $1.2M
Geode Capital Management, LLC 0.00% Add +32.0% 1,278,156 $773K
Qube Research & Technologies Ltd 0.00% Reduce -36.0% 1,167,269 $706K
Morgan Stanley 0.00% Add +108.2% 713,315 $431K
Hudson Bay Capital Management LP 0.00% New 673,764 $408K
Deutsche Bank AG 0.00% Reduce 0.0% 622,226 $380K
State Street Corp. 0.00% Add +47.1% 518,518 $314K
Susquehanna International Group, LLP 0.00% Reduce -18.7% 477,157 $289K
Rockefeller Capital Management L.P. 0.00% New 391,897 $237K
Hennion & Walsh Asset Management, Inc. 0.01% Reduce -1.8% 282,848 $171K
Birchview Capital, LP 0.10% Reduce -19.6% 225,000 $136K
Royal Bank of Canada 0.00% Add +15241.3% 202,812 $122K
Two Sigma Investments, LP 0.00% Reduce -66.5% 198,933 $120K
Northern Trust Corp. 0.00% Reduce -0.9% 173,715 $105K
Squarepoint Ops LLC 0.00% Add +1445.1% 158,865 $96K
Goldman Sachs Group Inc. 0.00% Reduce -78.8% 155,141 $94K
AQR Capital Management 0.00% Reduce -61.8% 109,687 $66K
Scientech Research LLC 0.02% New 105,110 $64K
CreativeOne Wealth, LLC 0.00% Reduce -4.0% 100,012 $60K
HRT Financial LP 0.00% Add +71.8% 94,870 $57K
Bank of New York Mellon Corp 0.00% No change 79,418 $48K
Group One Trading LLC 0.00% Reduce -33.8% 75,261 $46K
Tudor Investment Corporation 0.00% No change 57,454 $35K
Virtu Financial LLC 0.00% New 51,017 $31K
Sphera Funds Management LTD. 0.01% No change 50,000 $30K
Adams Wealth Management 0.00% No change 38,637 $22K
CacheTech Inc. 0.00% No change 38,637 $22K
Tower Research Capital LLC (TRC) 0.00% Reduce -5.2% 34,355 $21K
Point72 Asia (Singapore) Pte. Ltd. 0.00% New 32,702 $20K
Roble, Belko & Company, Inc 0.00% No change 30,841 $19K
Ethic Inc. 0.00% Reduce -5.0% 27,193 $16K
China Universal Asset Management Co., Ltd. 0.00% Reduce -11.2% 25,243 $15K
XTX Topco Ltd 0.00% New 23,579 $14K
Wolverine Trading, LLC 0.00% New 20,405 $12K
FMR LLC 0.00% Reduce -2.0% 17,482 $11K
Cresset Asset Management, LLC 0.00% New 17,091 $10K
Cerity Partners LLC 0.00% Reduce -42.5% 16,803 $10K
SG Americas Securities, LLC 0.00% Reduce -30.3% 16,404 $10K
Vanguard Personalized Indexing Management, LLC 0.00% Add +39.8% 16,244 $10K
Bank of America Corp. 0.00% Reduce -35.8% 11,670 $7K
Perennial Investment Advisors, LLC 0.00% No change 11,600 $7K
Stratos Wealth Advisors, LLC 0.00% Reduce -13.3% 10,500 $6K
Algorithmic Investment Models, LLC 0.00% New 10,403 $6K
JPMorgan Chase & Co. 0.00% Add +284.6% 7,631 $5K
Citigroup Inc. 0.00% Reduce -8.1% 6,841 $4K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +1.8% 5,568 $3K
Barclays PLC 0.00% Reduce -52.6% 5,265 $3K
AlphaQuest LLC 0.00% No change 4,661 $3K
BNP Paribas Financial Markets 0.00% Reduce -57.6% 3,475 $2K
Capital Advisors, Ltd. LLC 0.00% No change 2,367 $1K
Sunbelt Securities, Inc. 0.00% No change 1,000 $605
SBI Securities Co., Ltd. 0.00% Reduce -92.4% 823 $498
Rhumbline Advisers 0.00% No change 544 $329
Parallel Advisors, LLC 0.00% New 100 $60
Federation des caisses Desjardins du Quebec 0.00% No change 84 $51
Cwm, LLC 0.00% Reduce -93.2% 376 $0

"% of holder's portfolio" is APLT's weight in each manager's 13F, not the share of Applied Therapeutics Inc. the manager owns.