Caris Life SciencesCAI
13F holders, Q4 2025 (December 31)186holders +48
73new positions
27sold out
8famous investors
$26.95avg. 13F price*
At the end of Q4 2025, 186 institutions reported holding Caris Life Sciences Inc. (CAI) in their 13F filings, up 48 from Q3 2025. 73 opened new positions and 27 sold out. The largest holders were J. H. Whitney Equity Partners VI, LLC ($546.5M), Sixth Street Partners Management Company, L.P. ($523.0M) and FMR LLC ($383.6M). 8 famous investors held it, including Philippe Laffont (0.7% of Coatue Management's portfolio), Steve Cohen (0.1% of Point72 Asset Management's portfolio) and Israel Englander (0.1% of Millennium Management's portfolio).
- Company
- Caris Life Sciences Inc.
- CUSIP
- 142152107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 73 | $184.6M |
| Exits | 27 | $275.1M |
All 13F filers, Q3 2025 → Q4 2025: 31,701,118 shares bought and 19,478,391 shares sold, net +12,222,727 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 186 holders
| J. H. Whitney Equity Partners VI, LLC | 100.00% | — | 20,256,615 | $546.5M |
| Sixth Street Partners Management Company, L.P. | 53.72% | Reduce -20.5% | 19,385,399 | $523.0M |
| FMR LLC | 0.02% | Add +47.6% | 14,217,768 | $383.6M |
| Coatue Management | 0.66% | Reduce -3.2% | 9,819,992 | $264.9M |
| T. Rowe Price Investment Management, Inc. | 0.16% | Add +14.7% | 9,205,959 | $248.4M |
| Braidwell LP | 8.08% | Add +6.8% | 7,816,142 | $210.9M |
| PointState Capital LP | 3.10% | Add +73.0% | 6,718,707 | $181.3M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -30.3% | 4,827,965 | $130.3M |
| Neuberger Berman Group LLC | 0.08% | Reduce -12.5% | 3,800,922 | $102.5M |
| Millennium Management | 0.07% | Reduce -7.3% | 3,652,647 | $98.5M |
| Orbimed Advisors LLC | 1.72% | Add +2.7% | 3,116,011 | $84.1M |
| Citadel Advisors | 0.06% | New | 3,113,956 | $84.0M |
| JPMorgan Chase & Co. | 0.00% | Add +185.0% | 2,445,281 | $66.0M |
| BlackRock, Inc. | 0.00% | Add +266.4% | 2,371,236 | $64.0M |
| UBS Group AG | 0.01% | Add +825.9% | 2,183,980 | $58.9M |
| Point72 Asset Management | 0.08% | Add +656.2% | 1,864,860 | $50.3M |
| Morgan Stanley | 0.00% | Add +17.0% | 1,794,991 | $48.4M |
| Balyasny Asset Management L.P. | 0.09% | Add +23902.9% | 1,660,280 | $44.8M |
| Longaeva Partners L.P. | 4.88% | Add +17.4% | 1,509,745 | $40.7M |
| Ameriprise Financial Inc. | 0.01% | Reduce -10.4% | 1,505,080 | $40.6M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.01% | Add +31.7% | 1,470,295 | $39.7M |
| Canada Pension Plan Investment Board | 0.03% | Add +10.7% | 1,464,558 | $39.5M |
| Clearbridge Investments, LLC | 0.03% | Add +2.5% | 1,416,207 | $38.2M |
| Perceptive Advisors LLC | 0.56% | Add +3.5% | 1,136,206 | $30.7M |
| FIL Ltd | 0.02% | Add +397.0% | 1,122,775 | $30.3M |
| Bank of America Corp. | 0.00% | Add +161.4% | 1,122,748 | $30.3M |
| Invesco Ltd. | 0.00% | Add +28.5% | 1,033,115 | $27.9M |
| Marshall Wace, LLP | 0.03% | Add +1108.5% | 1,002,734 | $27.1M |
| Massachusetts Financial Services Co. | 0.01% | Reduce -3.1% | 941,639 | $25.4M |
| Champlain Investment Partners, LLC | 0.26% | New | 939,365 | $25.3M |
| Ghisallo Capital Management LLC | 1.02% | Reduce -19.4% | 845,332 | $22.8M |
| TD Asset Management Inc | 0.02% | Add +248.1% | 773,852 | $20.9M |
| Woodline Partners LP | 0.08% | No change | 723,163 | $19.5M |
| Rock Springs Capital Management LP | 0.95% | Reduce -13.4% | 687,500 | $18.5M |
| BNP Paribas Financial Markets | 0.01% | Add +57052.2% | 685,826 | $18.5M |
| Zevenbergen Capital Investments LLC | 0.33% | New | 543,185 | $14.7M |
| Seven Grand Managers, LLC | 1.02% | Add +395.1% | 495,095 | $13.4M |
| ARK Investment Management | 0.07% | Add +66.6% | 408,725 | $11.0M |
| Geode Capital Management, LLC | 0.00% | Reduce -6.4% | 372,979 | $10.1M |
| Goldman Sachs Group Inc. | 0.00% | Add +24.1% | 350,142 | $9.4M |
| Renaissance Technologies | 0.01% | Add +46.6% | 329,900 | $8.9M |
| Meridiem Capital Partners LP | 0.47% | New | 278,063 | $7.5M |
| Franklin Resources Inc. | 0.00% | Add +23.8% | 268,615 | $7.2M |
| State Street Corp. | 0.00% | Add +67.8% | 260,645 | $7.0M |
| Schonfeld Strategic Advisors LLC | 0.03% | New | 247,407 | $6.7M |
| Lazard Asset Management LLC | 0.01% | Reduce -12.5% | 242,779 | $6.6M |
| Holocene Advisors, LP | 0.01% | Add +39.0% | 237,897 | $6.4M |
| Picton Mahoney Asset Management | 0.06% | Add +3415.4% | 218,305 | $5.9M |
| Qube Research & Technologies Ltd | 0.01% | Add +532.0% | 206,993 | $5.6M |
| Worldquant Millennium Advisors LLC | 0.02% | Add +1771.4% | 188,861 | $5.1M |
| Tudor Investment Corporation | 0.03% | Reduce -31.1% | 182,382 | $4.9M |
| Jane Street Group, LLC | 0.01% | Add +1071.6% | 170,997 | $4.6M |
| Walleye Capital LLC | 0.03% | Reduce -49.2% | 162,915 | $4.4M |
| Oddo BHF Asset Management Sas | 0.17% | New | 162,313 | $4.4M |
| State of Wisconsin Investment Board | 0.01% | No change | 150,000 | $4.0M |
| Creative Planning | 0.00% | New | 149,856 | $4.0M |
| Parkman Healthcare Partners LLC | 0.32% | New | 125,000 | $3.4M |
| HRT Financial LP | 0.01% | New | 122,939 | $3.3M |
| Norges Bank | 0.00% | — | 110,294 | $3.0M |
| Jump Financial, LLC | 0.04% | New | 103,005 | $2.8M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -7.5% | 101,816 | $2.8M |
| Raymond James Financial Inc. | 0.00% | Add +2.8% | 97,518 | $2.6M |
| TD Waterhouse Canada Inc. | 0.02% | New | 92,653 | $2.5M |
| Pura Vida Investments, LLC | 9.07% | No change | 89,940 | $2.4M |
| Trexquant Investment LP | 0.02% | New | 82,705 | $2.2M |
| Dark Forest Capital Management LP | 0.10% | Add +146.9% | 78,163 | $2.1M |
| Sumitomo Mitsui Trust Group, Inc. | 0.00% | Add +26.5% | 75,330 | $2.0M |
| Burkehill Global Management, LP | 0.14% | No change | 75,000 | $2.0M |
| Engineers Gate Manager LP | 0.02% | Add +224.2% | 71,403 | $1.9M |
| Gotham Asset Management | 0.01% | Add +102.3% | 67,186 | $1.8M |
| Quantinno Capital Management LP | 0.00% | Reduce -10.1% | 64,922 | $1.8M |
| Squarepoint Ops LLC | 0.00% | New | 64,397 | $1.7M |
| Hamilton Lane Advisors LLC | 0.87% | New | 58,725 | $1.6M |
| Amova Asset Management Americas, Inc. | 0.02% | Add +15.5% | 54,719 | $1.5M |
| Barclays PLC | 0.00% | Add +1603.4% | 54,117 | $1.5M |
| Caption Management, LLC | 0.06% | New | 50,888 | $1.4M |
| Bank of New York Mellon Corp | 0.00% | Add +102.7% | 50,403 | $1.4M |
| Element Capital Management LLC | 0.70% | New | 50,000 | $1.3M |
| China Universal Asset Management Co., Ltd. | 0.10% | New | 45,976 | $1.2M |
| Mangrove Partners Im, LLC | 0.09% | New | 42,483 | $1.1M |
| VARCOV Co. | 0.43% | — | 40,037 | $1.1M |
| Maven Securities LTD | 0.14% | New | 40,000 | $1.1M |
| Northern Trust Corp. | 0.00% | Reduce -19.0% | 36,948 | $997K |
| Voloridge Investment Management, LLC | 0.00% | New | 35,050 | $946K |
| Vanguard Group Inc. | 0.00% | Reduce -80.9% | 33,505 | $904K |
| Envestnet Asset Management Inc. | 0.00% | New | 31,029 | $837K |
| Citigroup Inc. | 0.00% | Reduce -36.6% | 30,725 | $829K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | New | 30,157 | $814K |
| Bessemer Group Inc. | 0.00% | New | 26,670 | $719K |
| Group One Trading LLC | 0.02% | New | 26,343 | $711K |
| LPL Financial LLC | 0.00% | Add +60.8% | 25,711 | $694K |
| Deutsche Bank AG | 0.00% | No change | 25,290 | $682K |
| PEAK6 LLC | 0.02% | New | 24,800 | $669K |
| Sei Investments Co. | 0.00% | New | 24,451 | $660K |
| Sandia Investment Management LP | 1.60% | Add +174.4% | 23,600 | $637K |
| Rhumbline Advisers | 0.00% | Add +8.8% | 23,381 | $631K |
| WPWealth LLP | 0.10% | Reduce -0.1% | 23,025 | $621K |
| Nuveen, LLC | 0.00% | No change | 22,413 | $605K |
| PDT Partners, LLC | 0.04% | New | 22,016 | $594K |
| Oak Ridge Investments LLC | 0.04% | New | 21,820 | $589K |
| Alliancebernstein L.P. | 0.00% | Reduce -98.3% | 20,387 | $550K |
| Diversified Trust Co. | 0.01% | New | 20,000 | $540K |
| MSA Advisors, LLC | 0.13% | No change | 19,200 | $518K |
| Magnetar Financial LLC | 0.01% | New | 17,493 | $472K |
| Boothbay Fund Management, LLC | 0.01% | New | 16,490 | $445K |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 0.03% | Add +86.7% | 15,546 | $419K |
| Gsa Capital Partners LLP | 0.04% | New | 15,235 | $411K |
| Renaissance Capital LLC | 0.28% | Reduce -49.3% | 14,429 | $389K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | New | 13,711 | $370K |
| Victory Capital Management Inc. | 0.00% | New | 13,263 | $358K |
| Lighthouse Investment Partners, LLC | 0.01% | New | 13,251 | $358K |
| US Bancorp \de | 0.00% | Add +2.1% | 12,989 | $350K |
| New York State Common Retirement Fund | 0.00% | New | 12,900 | $348K |
| ProShare Advisors LLC | 0.00% | New | 12,462 | $336K |
| Americana Partners, LLC | 0.01% | No change | 12,433 | $335K |
| Edmond DE Rothschild Holding S.A. | 0.00% | Add +63.5% | 12,265 | $331K |
| Michael & Susan Dell Foundation | 0.01% | New | 12,235 | $330K |
| Temasek Holdings (Private) Ltd | 0.00% | New | 12,235 | $330K |
| Axq Capital, LP | 0.07% | New | 12,212 | $329K |
| Clal Insurance Enterprises Holdings Ltd | 0.00% | New | 11,930 | $322K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +15.0% | 11,932 | $322K |
| Northwest & Ethical Investments L.P. | 0.01% | New | 10,600 | $290K |
| Knollwood Investment Advisory, LLC | 0.03% | New | 10,445 | $282K |
| CastleKnight Management LP | 0.02% | No change | 10,436 | $282K |
| Lykos Global Management, LP | 0.19% | — | 10,000 | $270K |
| Brevan Howard Capital Management LP | 0.01% | New | 9,767 | $264K |
| HSBC Holdings PLC | 0.00% | New | 9,601 | $261K |
| Treasurer of the State of North Carolina | 0.00% | Reduce -5.7% | 9,496 | $256K |
| Summit Trail Advisors, LLC | 0.00% | New | 9,292 | $251K |
| Triton Wealth Management, PLLC | 0.09% | Add +3.9% | 10,918 | $251K |
| Royal Bank of Canada | 0.00% | Add +115.4% | 9,244 | $250K |
| Wells Fargo & Company | 0.00% | Add +408.2% | 8,995 | $243K |
| Courier Capital LLC | 0.01% | New | 8,550 | $231K |
| Occudo Quantitative Strategies LP | 0.02% | New | 8,355 | $225K |
| Federation des caisses Desjardins du Quebec | 0.00% | New | 7,925 | $214K |
| Perbak Capital Partners LLP | 0.06% | Reduce -26.6% | 7,851 | $212K |
| Legal & General Group Plc | 0.00% | Add +199.6% | 6,881 | $186K |
| Public Employees Retirement System of Ohio | 0.00% | Reduce -2.5% | 6,821 | $184K |
| Bellevue Group AG | 0.00% | Reduce -33.2% | 6,418 | $173K |
| GF Fund Management Co. LTD. | 0.00% | New | 5,543 | $150K |
| Adams Street Partners LLC | 0.05% | New | 4,894 | $132K |
| Quantbot Technologies LP | 0.00% | New | 4,622 | $125K |
| Simplex Trading, LLC | 0.00% | Add +15.5% | 4,599 | $124K |
| Osaic Holdings, Inc. | 0.00% | Add +808.7% | 4,089 | $110K |
| Aquatic Capital Management LLC | 0.00% | New | 3,817 | $103K |
| Federated Hermes, Inc. | 0.00% | New | 3,000 | $81K |
| Aster Capital Management (DIFC) Ltd | 0.03% | New | 2,488 | $67K |
| Russell Investments Group, Ltd. | 0.00% | No change | 1,995 | $54K |
| MetLife Investment Management, LLC | 0.00% | Add +84.0% | 1,654 | $45K |
| Amalgamated Bank | 0.00% | Add +0.6% | 1,471 | $40K |
| California State Teachers Retirement System | 0.00% | Add +8.0% | 1,411 | $38K |
| Olistico Wealth, LLC | 0.02% | New | 1,152 | $31K |
| Bokf, NA | 0.00% | No change | 1,131 | $31K |
| Global Retirement Partners, LLC | 0.00% | Add +99900.0% | 1,000 | $27K |
| MAI Capital Management | 0.00% | New | 1,000 | $27K |
| Daiwa Securities Group Inc. | 0.00% | New | 850 | $23K |
| Sterling Capital Management LLC | 0.00% | Add +18.2% | 844 | $23K |
| Comerica Bank | 0.00% | Add +4.1% | 689 | $19K |
| Los Angeles Capital Management LLC | 0.00% | New | 565 | $18K |
| STRS Ohio | 0.00% | Add +1.3% | 543 | $15K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -63.6% | 446 | $12K |
| Brown Brothers Harriman & Co. | 0.00% | No change | 344 | $9K |
| Trust Co. of Vermont | 0.00% | New | 330 | $9K |
| Ascentis Wealth Management, LLC | 0.00% | No change | 200 | $5K |
| NewEdge Advisors, LLC | 0.00% | No change | 200 | $5K |
| Cwm, LLC | 0.00% | Reduce -77.5% | 175 | $5K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -79.5% | 175 | $5K |
| Versant Capital Management, Inc | 0.00% | New | 146 | $4K |
| Ancora Advisors LLC | 0.00% | New | 145 | $4K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +508.7% | 140 | $4K |
| J.Safra Asset Management Corp | 0.00% | Add +542.9% | 135 | $4K |
| GAMMA Investing LLC | 0.00% | New | 97 | $3K |
| Arax Advisory Partners | 0.00% | Reduce -56.7% | 94 | $3K |
| Cornerstone Planning Group LLC | 0.00% | New | 78 | $2K |
| Financial Management Professionals, Inc. | 0.00% | No change | 71 | $2K |
| Rockefeller Capital Management L.P. | 0.00% | New | 35 | $944 |
| SageView Advisory Group, LLC | 0.00% | New | 32 | $864 |
| Farther Finance Advisors, LLC | 0.00% | New | 29 | $782 |
| Jones Financial Companies LLLP | 0.00% | Reduce -82.1% | 25 | $675 |
| UMB Bank, n.a. | 0.00% | New | 6 | $162 |
| Cedar Mountain Advisors, LLC | 0.00% | No change | 5 | $135 |
| Rothschild Investment LLC | 0.00% | New | 3 | $81 |
| IFP Advisors, Inc | 0.00% | New | 3 | $81 |
| Allworth Financial LP | 0.00% | New | 2 | $54 |
| DekaBank Deutsche Girozentrale | 0.00% | New | 146,100 | $0 |
| Covestor Ltd | 0.00% | New | 16 | $0 |
"% of holder's portfolio" is CAI's weight in each manager's 13F, not the share of Caris Life Sciences Inc. the manager owns.