Caris Life SciencesCAI
13F holders, Q1 2026 (March 31)202holders +16
51new positions
35sold out
10famous investors
$17.84avg. 13F price*
At the end of Q1 2026, 202 institutions reported holding Caris Life Sciences Inc. (CAI) in their 13F filings, up 16 from Q4 2025. 51 opened new positions and 35 sold out. The largest holders were FMR LLC ($550.4M), J. H. Whitney Equity Partners VI, LLC ($326.4M) and Sixth Street Partners Management Company, L.P. ($257.2M). 10 famous investors held it, including Stanley Druckenmiller (1.2% of Duquesne Family Office's portfolio), Philippe Laffont (0.6% of Coatue Management's portfolio) and Joel Greenblatt (0.0% of Gotham Asset Management's portfolio).
- Company
- Caris Life Sciences Inc.
- CUSIP
- 142152107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 51 | $75.8M |
| Exits | 35 | $216.4M |
All 13F filers, Q4 2025 → Q1 2026: 35,282,572 shares bought and 30,769,434 shares sold, net +4,513,138 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 202 holders
| FMR LLC | 0.03% | Add +116.5% | 30,785,585 | $550.4M |
| J. H. Whitney Equity Partners VI, LLC | 100.00% | Reduce -9.9% | 18,256,615 | $326.4M |
| Sixth Street Partners Management Company, L.P. | 36.19% | Reduce -25.8% | 14,385,399 | $257.2M |
| Coatue Management | 0.60% | No change | 9,819,992 | $175.6M |
| Braidwell LP | 5.45% | Add +2.5% | 8,009,447 | $143.2M |
| PointState Capital LP | 3.06% | Add +9.6% | 7,360,446 | $131.6M |
| T. Rowe Price Investment Management, Inc. | 0.07% | Reduce -39.3% | 5,588,257 | $99.9M |
| BlackRock, Inc. | 0.00% | Add +104.8% | 4,857,112 | $86.8M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -9.4% | 4,371,771 | $78.2M |
| Vanguard Portfolio Management LLC | 0.00% | — | 3,758,462 | $67.2M |
| Neuberger Berman Group LLC | 0.05% | Reduce -5.5% | 3,590,586 | $64.2M |
| Vanguard Capital Management LLC | 0.00% | — | 3,329,021 | $59.5M |
| JPMorgan Chase & Co. | 0.00% | Add +41.5% | 3,460,215 | $58.3M |
| Orbimed Advisors LLC | 1.14% | Reduce -9.9% | 2,806,811 | $50.2M |
| UBS Group AG | 0.01% | Add +25.7% | 2,745,811 | $49.1M |
| Los Angeles Capital Management LLC | 0.16% | Add +405139.3% | 2,289,602 | $40.9M |
| Duquesne Family Office | 1.15% | New | 1,894,450 | $33.9M |
| BNP Paribas Financial Markets | 0.02% | Add +135.4% | 1,614,286 | $28.9M |
| Clearbridge Investments, LLC | 0.02% | Add +9.6% | 1,551,774 | $27.7M |
| FIL Ltd | 0.02% | Add +37.7% | 1,546,091 | $27.6M |
| Millennium Management | 0.02% | Reduce -58.2% | 1,527,756 | $27.3M |
| Canada Pension Plan Investment Board | 0.02% | Reduce -9.7% | 1,322,752 | $23.7M |
| Invesco Ltd. | 0.00% | Add +18.3% | 1,222,278 | $21.9M |
| Champlain Investment Partners, LLC | 0.27% | Add +28.6% | 1,207,963 | $21.6M |
| Capital World Investors | 0.00% | New | 1,180,173 | $21.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -21.8% | 1,149,133 | $20.5M |
| Morgan Stanley | 0.00% | Reduce -39.9% | 1,079,417 | $19.3M |
| State Street Corp. | 0.00% | Add +277.9% | 984,953 | $17.6M |
| Point72 Asset Management | 0.03% | Reduce -50.8% | 918,331 | $16.4M |
| Geode Capital Management, LLC | 0.00% | Add +108.7% | 778,532 | $13.9M |
| Gotham Asset Management | 0.04% | Add +1008.0% | 744,426 | $13.3M |
| Woodline Partners LP | 0.05% | No change | 723,163 | $12.9M |
| TD Asset Management Inc | 0.01% | Reduce -13.4% | 670,388 | $12.0M |
| Nuveen, LLC | 0.00% | Add +2860.7% | 663,578 | $11.9M |
| Zevenbergen Capital Investments LLC | 0.31% | Add +12.3% | 610,233 | $10.9M |
| Sei Investments Co. | 0.01% | Add +2348.6% | 598,712 | $10.7M |
| Rock Springs Capital Management LP | 0.59% | Reduce -18.1% | 563,000 | $10.1M |
| Bank of America Corp. | 0.00% | Reduce -53.4% | 523,268 | $9.4M |
| Trexquant Investment LP | 0.06% | Add +493.1% | 490,536 | $8.8M |
| Renaissance Technologies | 0.01% | Add +36.4% | 449,900 | $8.0M |
| Goldman Sachs Group Inc. | 0.00% | Add +17.2% | 410,340 | $7.3M |
| Ameriprise Financial Inc. | 0.00% | Reduce -72.9% | 408,079 | $7.3M |
| Lazard Asset Management LLC | 0.01% | Add +26.0% | 305,911 | $5.5M |
| Picton Mahoney Asset Management | 0.05% | Add +27.8% | 278,977 | $5.0M |
| Massachusetts Financial Services Co. | 0.00% | Reduce -71.5% | 267,950 | $4.8M |
| Ghisallo Capital Management LLC | 0.12% | Reduce -70.4% | 250,000 | $4.5M |
| Federated Hermes, Inc. | 0.01% | Add +7871.7% | 239,150 | $4.3M |
| Bank of New York Mellon Corp | 0.00% | Add +359.6% | 231,661 | $4.1M |
| Parkman Healthcare Partners LLC | 0.43% | Add +83.9% | 229,912 | $4.1M |
| Arrowstreet Capital, Limited Partnership | 0.00% | New | 210,593 | $3.8M |
| Worldquant Millennium Advisors LLC | 0.01% | Add +3.1% | 194,710 | $3.5M |
| Qube Research & Technologies Ltd | 0.00% | Reduce -9.4% | 187,480 | $3.4M |
| Northern Trust Corp. | 0.00% | Add +371.1% | 174,065 | $3.1M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +50.8% | 153,512 | $2.7M |
| Quantinno Capital Management LP | 0.00% | Add +117.0% | 140,909 | $2.5M |
| Aquatic Capital Management LLC | 0.07% | Add +3570.3% | 140,097 | $2.5M |
| State of Wisconsin Investment Board | 0.01% | Reduce -9.1% | 136,334 | $2.4M |
| D. E. Shaw & Co. | 0.00% | New | 129,577 | $2.3M |
| Man Group plc | 0.00% | New | 128,971 | $2.3M |
| Oddo BHF Asset Management Sas | 0.08% | Reduce -32.5% | 109,539 | $2.0M |
| Engineers Gate Manager LP | 0.02% | Add +43.9% | 102,757 | $1.8M |
| Tudor Investment Corporation | 0.01% | Reduce -45.0% | 100,327 | $1.8M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 96,581 | $1.7M |
| Raymond James Financial Inc. | 0.00% | Reduce -7.5% | 90,233 | $1.6M |
| Pura Vida Investments, LLC | 10.81% | No change | 89,940 | $1.6M |
| Smartleaf Asset Management LLC | 0.06% | New | 94,051 | $1.6M |
| Alliancebernstein L.P. | 0.00% | Add +180.0% | 57,076 | $1.5M |
| XTX Topco Ltd | 0.02% | New | 78,506 | $1.4M |
| Creative Planning | 0.00% | Reduce -48.0% | 77,998 | $1.4M |
| Citadel Advisors | 0.00% | Reduce -97.5% | 77,810 | $1.4M |
| Citigroup Inc. | 0.00% | Add +151.2% | 77,180 | $1.4M |
| Burkehill Global Management, LP | 0.07% | No change | 75,000 | $1.3M |
| Rhumbline Advisers | 0.00% | Add +219.2% | 74,622 | $1.3M |
| Barclays PLC | 0.00% | Add +37.5% | 74,423 | $1.3M |
| Twinbeech Capital LP | 0.11% | New | 58,100 | $1.0M |
| Sumitomo Mitsui Trust Group, Inc. | 0.00% | Reduce -24.7% | 56,744 | $1.0M |
| Envestnet Asset Management Inc. | 0.00% | Add +72.8% | 53,607 | $958K |
| Susquehanna International Group, LLP | 0.00% | New | 53,066 | $949K |
| Natixis | 0.00% | New | 52,778 | $944K |
| China Universal Asset Management Co., Ltd. | 0.07% | Add +8.9% | 50,069 | $895K |
| Renaissance Capital LLC | 0.60% | Add +201.4% | 43,484 | $826K |
| New York State Common Retirement Fund | 0.00% | Add +254.3% | 45,700 | $817K |
| Franklin Resources Inc. | 0.00% | Reduce -83.3% | 44,975 | $804K |
| Dark Forest Capital Management LP | 0.07% | Reduce -44.9% | 43,080 | $770K |
| LPL Financial LLC | 0.00% | Add +63.5% | 42,041 | $752K |
| CastleKnight Management LP | 0.03% | Add +293.2% | 41,036 | $734K |
| Entropy Technologies, LP | 0.03% | New | 40,503 | $724K |
| Police & Firemen's Retirement System of New Jersey | 0.01% | Add +231.0% | 39,497 | $706K |
| Treasurer of the State of North Carolina | 0.00% | Add +310.8% | 39,005 | $697K |
| Americana Partners, LLC | 0.02% | Add +208.6% | 38,367 | $686K |
| Deutsche Bank AG | 0.00% | Add +51.4% | 38,290 | $685K |
| Amova Asset Management Americas, Inc. | 0.01% | Reduce -34.0% | 36,133 | $646K |
| Caption Management, LLC | 0.03% | Reduce -34.5% | 33,332 | $596K |
| Diversified Trust Co. | 0.01% | Add +62.5% | 32,500 | $581K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +0.6% | 30,350 | $543K |
| AQR Capital Management | 0.00% | New | 28,994 | $518K |
| Legal & General Group Plc | 0.00% | Add +318.3% | 28,781 | $515K |
| Park Avenue Securities LLC | 0.00% | New | 27,937 | $500K |
| Dimensional Fund Advisors LP | 0.00% | New | 27,492 | $492K |
| Public Employees Retirement System of Ohio | 0.00% | Add +288.8% | 26,519 | $474K |
| Oak Ridge Investments LLC | 0.03% | Add +19.6% | 26,106 | $467K |
| Charles Schwab Investment Management Inc. | 0.00% | New | 25,331 | $453K |
| Russell Investments Group, Ltd. | 0.00% | Add +1166.6% | 25,269 | $452K |
| State Board of Administration of Florida Retirement System | 0.00% | New | 24,293 | $434K |
| WPWealth LLP | 0.06% | No change | 23,025 | $412K |
| Edmond DE Rothschild Holding S.A. | 0.01% | Add +84.4% | 22,615 | $404K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 22,584 | $404K |
| Axq Capital, LP | 0.05% | Add +81.2% | 22,125 | $396K |
| PDT Partners, LLC | 0.02% | No change | 22,016 | $394K |
| Perbak Capital Partners LLP | 0.10% | Add +180.2% | 22,001 | $393K |
| Amundi | 0.00% | New | 20,972 | $375K |
| Verition Fund Management LLC | 0.00% | New | 20,000 | $358K |
| MSA Advisors, LLC | 0.10% | No change | 19,200 | $343K |
| Courier Capital LLC | 0.02% | Add +122.2% | 19,000 | $340K |
| Royal Bank of Canada | 0.00% | Add +101.8% | 18,651 | $333K |
| Group One Trading LLC | 0.01% | Reduce -31.0% | 18,173 | $325K |
| Wells Fargo & Company | 0.00% | Add +91.8% | 17,250 | $308K |
| HSBC Holdings PLC | 0.00% | Add +71.8% | 16,494 | $294K |
| TD Waterhouse Canada Inc. | 0.00% | Reduce -84.6% | 14,300 | $273K |
| American Century Companies Inc. | 0.00% | New | 14,940 | $267K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +7.3% | 14,717 | $263K |
| Savant Capital, LLC | 0.00% | New | 13,803 | $247K |
| Victory Capital Management Inc. | 0.00% | Add +4.1% | 13,802 | $247K |
| Natixis Advisors, LLC | 0.00% | New | 13,759 | $246K |
| Perigon Wealth Management, LLC | 0.00% | New | 13,500 | $241K |
| Northwest & Ethical Investments L.P. | 0.01% | Add +17.9% | 12,500 | $238K |
| IMC-Chicago, LLC | 0.00% | New | 12,919 | $231K |
| ProShare Advisors LLC | 0.00% | Add +1.3% | 12,622 | $226K |
| Jacobs Levy Equity Management, Inc. | 0.00% | New | 12,340 | $221K |
| Summit Trail Advisors, LLC | 0.00% | Add +32.5% | 12,317 | $220K |
| Quantum Portfolio Management LLC | 0.10% | New | 12,280 | $220K |
| Michael & Susan Dell Foundation | 0.01% | No change | 12,235 | $219K |
| Temasek Holdings (Private) Ltd | 0.00% | No change | 12,235 | $219K |
| Bessemer Group Inc. | 0.00% | Reduce -55.5% | 11,880 | $212K |
| Wedmont Private Capital | 0.01% | New | 10,715 | $209K |
| Jones Financial Companies LLLP | 0.00% | Add +49084.0% | 12,296 | $208K |
| Triton Wealth Management, PLLC | 0.08% | No change | 10,918 | $206K |
| Xponance LLC | 0.00% | New | 10,921 | $195K |
| Jefferies Financial Group Inc. | 0.00% | New | 10,745 | $192K |
| Knollwood Investment Advisory, LLC | 0.02% | No change | 10,445 | $187K |
| Emerald Advisers, LLC | 0.01% | New | 10,422 | $186K |
| Federation des caisses Desjardins du Quebec | 0.00% | Reduce -12.5% | 6,932 | $124K |
| Bellevue Group AG | 0.00% | No change | 6,418 | $115K |
| GF Fund Management Co. LTD. | 0.00% | Add +14.3% | 6,337 | $113K |
| Osaic Holdings, Inc. | 0.00% | Add +45.0% | 5,928 | $106K |
| California State Teachers Retirement System | 0.00% | Add +254.5% | 5,002 | $89K |
| Blue Owl Capital Holdings LP | 0.02% | New | 4,711 | $84K |
| Quantbot Technologies LP | 0.00% | Reduce -16.6% | 3,855 | $69K |
| MetLife Investment Management, LLC | 0.00% | Add +113.8% | 3,536 | $63K |
| Quadrant Capital Group LLC | 0.00% | New | 2,884 | $52K |
| Simplex Trading, LLC | 0.00% | Reduce -42.0% | 2,669 | $48K |
| STRS Ohio | 0.00% | Add +301.3% | 2,179 | $39K |
| Sterling Capital Management LLC | 0.00% | Add +128.3% | 1,927 | $34K |
| Ancora Advisors LLC | 0.00% | Add +1226.2% | 1,923 | $34K |
| Versant Capital Management, Inc | 0.00% | Add +1100.7% | 1,753 | $31K |
| Fifth Third Bancorp | 0.00% | New | 1,749 | $31K |
| PNC Financial Services Group, Inc. | 0.00% | Add +839.4% | 1,644 | $29K |
| US Bancorp \de | 0.00% | Reduce -88.4% | 1,511 | $27K |
| Olistico Wealth, LLC | 0.01% | Add +23.5% | 1,423 | $25K |
| Bokf, NA | 0.00% | No change | 1,131 | $20K |
| MAI Capital Management | 0.00% | Add +3.5% | 1,035 | $19K |
| Arax Advisory Partners | 0.00% | Add +825.5% | 870 | $16K |
| Cwm, LLC | 0.00% | Add +394.9% | 866 | $15K |
| Zions Bancorporation, National Association | 0.00% | New | 848 | $15K |
| J.Safra Asset Management Corp | 0.00% | Add +420.0% | 702 | $13K |
| Albion Financial Group | 0.00% | New | 678 | $12K |
| CX Institutional | 0.00% | New | 684 | $12K |
| GAMMA Investing LLC | 0.00% | Add +535.0% | 616 | $11K |
| Vanguard Global Advisers, LLC | 0.00% | — | 525 | $9K |
| Quent Capital, LLC | 0.00% | New | 516 | $9K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -0.5% | 444 | $8K |
| Nisa Investment Advisors, LLC | 0.00% | New | 422 | $8K |
| Brown Brothers Harriman & Co. | 0.00% | No change | 344 | $6K |
| Covestor Ltd | 0.00% | Add +1800.0% | 304 | $5K |
| Signaturefd, LLC | 0.00% | New | 220 | $4K |
| Ascentis Wealth Management, LLC | 0.00% | No change | 200 | $4K |
| NewEdge Advisors, LLC | 0.00% | No change | 200 | $4K |
| Owl Creek Wealth Partners LLC | 0.00% | — | 190 | $3K |
| Larson Financial Group LLC | 0.00% | New | 152 | $3K |
| Farther Finance Advisors, LLC | 0.00% | Add +355.2% | 132 | $3K |
| Rockefeller Capital Management L.P. | 0.00% | Add +285.7% | 135 | $2K |
| First Horizon Corp. | 0.00% | New | 107 | $2K |
| Advisory Services Network, LLC | 0.00% | New | 100 | $2K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -29.3% | 99 | $2K |
| Financial Management Professionals, Inc. | 0.00% | Add +28.2% | 91 | $2K |
| Cornerstone Planning Group LLC | 0.00% | No change | 78 | $1K |
| Clearstead Trust, LLC | 0.00% | New | 73 | $1K |
| Allworth Financial LP | 0.00% | Add +2850.0% | 59 | $1K |
| Huntington National Bank | 0.00% | New | 36 | $644 |
| EverSource Wealth Advisors, LLC | 0.00% | New | 34 | $608 |
| Essential Partners LLC | 0.00% | New | 33 | $590 |
| UMB Bank, n.a. | 0.00% | Add +400.0% | 30 | $536 |
| MassMutual Private Wealth & Trust, FSB | 0.00% | New | 29 | $519 |
| Caitong International Asset Management Co., Ltd | 0.00% | New | 24 | $429 |
| Rothschild Investment LLC | 0.00% | Add +533.3% | 19 | $340 |
| IFP Advisors, Inc | 0.00% | Add +100.0% | 6 | $107 |
| Freestone Grove Partners LP | 0.00% | New | 6 | $107 |
| Cedar Mountain Advisors, LLC | 0.00% | No change | 5 | $89 |
| Wealth Preservation Advisors, LLC | 0.00% | New | 3 | $54 |
| Transamerica Financial Advisors, LLC | 0.00% | New | 3 | $53 |
| Activest Wealth Management | 0.00% | New | 1 | $18 |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 146,100 | $0 |
"% of holder's portfolio" is CAI's weight in each manager's 13F, not the share of Caris Life Sciences Inc. the manager owns.