Climb BioCLYM

13F holders, Q4 2025 (December 31)
65holders −3
14new positions
18sold out
4famous investors
$5.04avg. 13F price*

At the end of Q4 2025, 65 institutions reported holding Climb Bio Inc. (CLYM) in their 13F filings, down 3 from Q3 2025. 14 opened new positions and 18 sold out. The largest holders were Ra Capital Management, L.P. ($77.7M), MPM Bioimpact LLC ($10.7M) and T. Rowe Price Associates Inc. ($7.7M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Climb Bio Inc.
CUSIP
28658R106
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150 Q1 2024: 21Q1 2024Q2 2024: 47Q2 2024Q3 2024: 71Q3 2024Q4 2024: 79Q4 2024Q1 2025: 75Q1 2025Q2 2025: 69Q2 2025Q3 2025: 68Q3 2025Q4 2025: 65Q4 2025Q1 2026: 80Q1 2026Q2 2026: 108Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions14$23.4M
Exits18$6.0M

All 13F filers, Q3 2025 → Q4 2025: 10,660,166 shares bought and 24,599,095 shares sold, net −13,938,929 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 65 holders

Ra Capital Management, L.P. 0.80% Reduce -64.0% 11,293,828 $77.7M
MPM Bioimpact LLC 1.22% New 2,671,480 $10.7M
T. Rowe Price Associates Inc. 0.00% Add +265.1% 1,923,639 $7.7M
ADAR1 Capital Management, LLC 0.43% Add +972.8% 1,432,475 $5.7M
Vanguard Group Inc. 0.00% Add +1.9% 1,340,504 $5.4M
Affinity Asset Advisors, LLC 0.39% No change 1,300,000 $5.2M
Kynam Capital Management, LP 0.27% No change 1,028,341 $4.1M
Great Point Partners LLC 1.27% New 979,534 $3.9M
Sphera Funds Management LTD. 0.78% Add +114.4% 932,247 $3.7M
Point72 Asset Management 0.00% New 716,680 $2.9M
Driehaus Capital Management LLC 0.02% New 600,946 $2.4M
Two Sigma Investments, LP 0.00% Add +402.9% 566,712 $2.3M
Peapod Lane Capital LLC 1.93% Add +0.7% 565,992 $2.3M
Nan Fung Trinity (hk) Ltd. 0.15% No change 463,654 $1.9M
Susquehanna International Group, LLP 0.00% Add +212.6% 445,342 $1.8M
Kotler Kevin 1.18% — 400,000 $1.6M
BlackRock, Inc. 0.00% Reduce -47.1% 389,309 $1.6M
Renaissance Technologies 0.00% Reduce -40.3% 320,600 $1.3M
Geode Capital Management, LLC 0.00% Reduce -0.3% 310,756 $1.2M
Marshall Wace, LLP 0.00% Add +32.2% 304,015 $1.2M
Millennium Management 0.00% Reduce -37.2% 296,314 $1.2M
TD Asset Management Inc 0.00% Add +175.4% 246,200 $985K
Citadel Advisors 0.00% New 239,043 $956K
Goldman Sachs Group Inc. 0.00% Add +205.1% 224,883 $900K
683 Capital Management, LLC 0.07% New 201,652 $807K
Jane Street Group, LLC 0.00% Add +135.3% 187,403 $750K
Bridgeway Capital Management, LLC 0.01% Add +45.8% 159,300 $637K
Morgan Stanley 0.00% Add +72.0% 148,538 $594K
Manufacturers Life Insurance Company, The 0.00% Add +261.5% 140,617 $567K
Ameriprise Financial Inc. 0.00% New 139,529 $558K
State Street Corp. 0.00% Add +25.0% 128,900 $516K
Two Sigma Advisers, LP 0.00% Add +54.1% 124,700 $499K
Northern Trust Corp. 0.00% Reduce -0.6% 124,670 $499K
ArchPoint Investors 0.12% New 121,400 $486K
Squadron Capital Management LLC 0.18% — 100,000 $400K
OMERS ADMINISTRATION Corp 0.00% New 85,466 $342K
Seven Fleet Capital Management LP 0.21% — 76,400 $306K
UBS Group AG 0.00% Reduce -82.4% 71,323 $285K
LPL Financial LLC 0.00% Add +1.6% 62,000 $248K
Barclays PLC 0.00% Add +149.9% 61,853 $247K
Hudson Bay Capital Management LP 0.00% New 48,736 $195K
XTX Topco Ltd 0.00% Add +19.4% 34,852 $139K
Qube Research & Technologies Ltd 0.00% Reduce -5.5% 34,596 $138K
Citizens Financial Group Inc. 0.00% Reduce -38.8% 28,168 $113K
HSBC Holdings PLC 0.00% Add +107.2% 24,744 $99K
Prelude Capital Management, LLC 0.01% Reduce -51.1% 19,918 $80K
Balyasny Asset Management L.P. 0.00% New 14,236 $57K
Chicago Partners Investment Group LLC 0.00% Add +6.1% 10,962 $55K
Vanguard Personalized Indexing Management, LLC 0.00% Reduce -23.5% 11,127 $45K
Blair William & Co. 0.00% New 11,000 $44K
Virtu Financial LLC 0.00% New 10,655 $43K
Scientech Research LLC 0.03% New 10,428 $42K
Citigroup Inc. 0.00% Reduce -96.9% 10,331 $41K
Persistent Asset Partners Ltd 0.02% Reduce -67.3% 9,228 $37K
FMR LLC 0.00% Reduce -11.1% 6,349 $25K
Bank of America Corp. 0.00% Reduce -12.0% 5,063 $20K
Tower Research Capital LLC (TRC) 0.00% Reduce -74.7% 3,357 $13K
Harbour Investments, Inc. 0.00% No change 2,000 $8K
Osaic Holdings, Inc. 0.00% Reduce -97.3% 600 $2K
Nisa Investment Advisors, LLC 0.00% No change 573 $2K
BNP Paribas Financial Markets 0.00% Reduce -72.3% 513 $2K
Royal Bank of Canada 0.00% Reduce -41.0% 408 $1K
JPMorgan Chase & Co. 0.00% Reduce -99.8% 46 $184
Deutsche Bank AG 0.00% No change 1 $4
Cwm, LLC 0.00% Reduce -72.9% 29 $0

"% of holder's portfolio" is CLYM's weight in each manager's 13F, not the share of Climb Bio Inc. the manager owns.