Cytomx TherapeuticsCTMX
13F holders, Q4 2025 (December 31)122holders +19
34new positions
20sold out
3famous investors
$4.26avg. 13F price*
At the end of Q4 2025, 122 institutions reported holding Cytomx Therapeutics Inc. (CTMX) in their 13F filings, up 19 from Q3 2025. 34 opened new positions and 20 sold out. The largest holders were FMR LLC ($105.2M), Venrock Adviser, LLC ($66.3M) and Perceptive Advisors LLC ($41.2M). 3 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Cytomx Therapeutics Inc.
- CUSIP
- 23284F105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 34 | $25.1M |
| Exits | 20 | $67.5M |
All 13F filers, Q3 2025 → Q4 2025: 37,258,297 shares bought and 31,498,851 shares sold, net +5,759,446 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 122 holders
| FMR LLC | 0.01% | Add +60.4% | 24,688,109 | $105.2M |
| Venrock Adviser, LLC | 3.27% | No change | 15,561,500 | $66.3M |
| Perceptive Advisors LLC | 0.76% | No change | 9,680,185 | $41.2M |
| Kynam Capital Management, LP | 2.49% | Add +145.9% | 8,966,077 | $38.2M |
| Vanguard Group Inc. | 0.00% | Reduce -5.3% | 8,475,584 | $36.1M |
| Commodore Capital LP | 2.18% | No change | 7,692,300 | $32.8M |
| Point72 Asset Management | 0.04% | Add +27.6% | 5,189,538 | $22.1M |
| State Street Corp. | 0.00% | Add +697.1% | 5,140,931 | $21.9M |
| Baker Bros. Advisors LP | 0.11% | No change | 4,250,826 | $18.1M |
| ADAR1 Capital Management, LLC | 1.33% | Add +3.4% | 4,182,769 | $17.8M |
| Balyasny Asset Management L.P. | 0.03% | Reduce -1.0% | 3,872,202 | $16.5M |
| Financial Engines Advisors L.L.C. | 0.03% | Add +177.2% | 3,828,717 | $16.3M |
| BlackRock, Inc. | 0.00% | Add +54.0% | 3,669,393 | $15.6M |
| Orbimed Advisors LLC | 0.31% | Reduce -58.3% | 3,525,650 | $15.0M |
| Ikarian Capital, LLC | 1.75% | Reduce -5.9% | 3,172,616 | $13.5M |
| Vivo Capital, LLC | 0.79% | No change | 2,884,615 | $12.3M |
| Eversept Partners, LP | 0.60% | New | 2,507,090 | $10.7M |
| Goldman Sachs Group Inc. | 0.00% | Add +449.6% | 2,460,944 | $10.5M |
| Woodline Partners LP | 0.04% | No change | 2,337,005 | $10.0M |
| Two Sigma Investments, LP | 0.01% | Add +113.9% | 1,560,755 | $6.6M |
| Geode Capital Management, LLC | 0.00% | Reduce -2.8% | 1,525,666 | $6.5M |
| Dimensional Fund Advisors LP | 0.00% | Add +185.9% | 1,289,656 | $5.5M |
| Marshall Wace, LLP | 0.00% | Add +4.7% | 1,156,936 | $4.9M |
| Qube Research & Technologies Ltd | 0.01% | Add +766.2% | 1,061,128 | $4.5M |
| Stempoint Capital LP | 0.76% | New | 1,036,311 | $4.4M |
| Susquehanna International Group, LLP | 0.01% | Add +267.0% | 981,598 | $4.2M |
| Boothbay Fund Management, LLC | 0.10% | Reduce -27.7% | 894,663 | $3.8M |
| Bank of America Corp. | 0.00% | Reduce -12.8% | 876,305 | $3.7M |
| Acadian Asset Management LLC | 0.01% | Add +30.9% | 856,056 | $3.6M |
| Exome Asset Management LLC | 1.57% | No change | 745,305 | $3.2M |
| Elmind Capital, LP | 0.88% | — | 700,000 | $3.0M |
| Jane Street Group, LLC | 0.00% | Add +51.3% | 607,218 | $2.6M |
| Assenagon Asset Management S.A. | 0.00% | Reduce -18.8% | 592,696 | $2.5M |
| First Trust Advisors LP | 0.00% | Add +5.3% | 423,168 | $1.8M |
| Northern Trust Corp. | 0.00% | Add +6.5% | 415,178 | $1.8M |
| Morgan Stanley | 0.00% | Add +25.6% | 401,191 | $1.7M |
| Silverarc Capital Management, LLC | 0.24% | New | 385,974 | $1.6M |
| Schulhoff & Co. Inc. | 0.67% | New | 374,850 | $1.6M |
| UBS Group AG | 0.00% | Add +1128.9% | 370,739 | $1.6M |
| Citadel Advisors | 0.00% | Reduce -81.0% | 342,304 | $1.5M |
| Barclays PLC | 0.00% | Add +22485.6% | 336,525 | $1.4M |
| Two Sigma Advisers, LP | 0.00% | Add +738.8% | 335,524 | $1.4M |
| Bank of New York Mellon Corp | 0.00% | Add +29.9% | 328,248 | $1.4M |
| Raymond James Financial Inc. | 0.00% | Add +8.0% | 316,971 | $1.4M |
| Millennium Management | 0.00% | Reduce -79.1% | 289,653 | $1.2M |
| Rafferty Asset Management, LLC | 0.00% | New | 273,584 | $1.2M |
| Ameriprise Financial Inc. | 0.00% | Add +45.0% | 229,599 | $989K |
| Prelude Capital Management, LLC | 0.06% | No change | 206,526 | $880K |
| Informed Momentum Co LLC | 0.10% | New | 203,823 | $868K |
| HighVista Strategies LLC | 0.21% | Reduce -24.6% | 193,941 | $826K |
| Sei Investments Co. | 0.00% | New | 124,124 | $529K |
| LPL Financial LLC | 0.00% | Add +30.9% | 113,440 | $483K |
| Canada Pension Plan Investment Board | 0.00% | New | 104,200 | $444K |
| Aspire Growth Partners LLC | 0.30% | No change | 102,254 | $436K |
| NLB Skladi, upravljanje premozenja, d.o.o. | 0.02% | — | 100,000 | $426K |
| Profund Advisors LLC | 0.01% | New | 98,633 | $420K |
| Citigroup Inc. | 0.00% | Add +1142.0% | 96,326 | $410K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 87,800 | $374K |
| Gsa Capital Partners LLP | 0.03% | Reduce -84.7% | 81,886 | $349K |
| Velan Capital Investment Management LP | 0.20% | No change | 80,000 | $341K |
| HRT Financial LP | 0.00% | New | 71,867 | $306K |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -22.4% | 68,687 | $293K |
| Miller Financial Services LLC | 0.34% | Add +1.5% | 68,000 | $290K |
| Virtus Investment Advisers, LLC | 0.07% | New | 63,491 | $270K |
| Brooklyn Investment Group | 0.01% | New | 61,474 | $258K |
| Congress Park Capital LLC | 0.07% | Reduce -43.3% | 58,922 | $251K |
| Merit Financial Group, LLC | 0.00% | No change | 53,243 | $227K |
| SG Americas Securities, LLC | 0.00% | New | 53,109 | $226K |
| Timothy G. Youngquist 2020 Irrevocable Trust | 0.19% | — | 51,155 | $218K |
| Hudson Bay Capital Management LP | 0.00% | New | 50,990 | $217K |
| Squarepoint Ops LLC | 0.00% | Add +4.5% | 49,897 | $213K |
| Seven Fleet Capital Management LP | 0.14% | — | 48,898 | $208K |
| Susquehanna Portfolio Strategies, LLC | 0.00% | No change | 48,012 | $205K |
| XTX Topco Ltd | 0.01% | Add +63.9% | 47,991 | $204K |
| Formidable Asset Management, LLC | 0.03% | Reduce -61.3% | 45,763 | $195K |
| Tidal Investments LLC | 0.00% | Reduce -61.3% | 45,763 | $195K |
| Baader Bank Aktiengesellschaft | 0.02% | New | 45,000 | $192K |
| Private Advisor Group, LLC | 0.00% | No change | 44,002 | $187K |
| Lighthouse Investment Partners, LLC | 0.00% | New | 32,040 | $136K |
| Cambria Investment Management, L.P. | 0.01% | New | 31,332 | $133K |
| Empowered Funds, LLC | 0.00% | New | 31,332 | $133K |
| China Universal Asset Management Co., Ltd. | 0.01% | New | 27,609 | $118K |
| Truvestments Capital LLC | 0.02% | Add +60.4% | 27,428 | $117K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -0.7% | 26,765 | $114K |
| Engineers Gate Manager LP | 0.00% | New | 26,539 | $113K |
| Mangrove Partners Im, LLC | 0.01% | New | 26,265 | $112K |
| HB Wealth Management, LLC | 0.00% | New | 25,000 | $107K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +826366.7% | 24,794 | $106K |
| JPMorgan Chase & Co. | 0.00% | Add +50.8% | 24,363 | $104K |
| Simplex Trading, LLC | 0.00% | New | 24,051 | $102K |
| Jefferies Financial Group Inc. | 0.00% | Reduce -55.1% | 23,764 | $101K |
| Ethos Financial Group, LLC | 0.01% | No change | 23,697 | $101K |
| Mariner, LLC | 0.00% | Add +116.4% | 22,180 | $94K |
| Invesco Ltd. | 0.00% | Reduce -2.0% | 21,976 | $94K |
| State of Wyoming | 0.01% | New | 21,511 | $92K |
| Jain Global LLC | 0.00% | Reduce -37.0% | 21,212 | $90K |
| Osaic Holdings, Inc. | 0.00% | Add +16.2% | 19,410 | $83K |
| Sanctuary Advisors, LLC | 0.00% | Reduce -44.7% | 19,140 | $82K |
| Forefront Analytics, LLC | 0.07% | Add +3.3% | 18,699 | $80K |
| Twinbeech Capital LP | 0.01% | New | 17,600 | $75K |
"% of holder's portfolio" is CTMX's weight in each manager's 13F, not the share of Cytomx Therapeutics Inc. the manager owns.